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203 Results Found

  • Article
  • Open Access
1 Citations
921 Views
35 Pages

2 December 2025

Understanding and improving web performance is essential for enhancing user experience, yet existing approaches remain largely correlation-based and lack causal interpretability. To address this limitation, we propose a causal-inference-driven framew...

  • Article
  • Open Access
4 Citations
2,731 Views
24 Pages

Causal Pathway Extraction from Web-Board Documents

  • Chaveevan Pechsiri and
  • Rapepun Piriyakul

3 November 2021

This research aim is to extract causal pathways, particularly disease causal pathways, through cause-effect relation (CErel) extraction from web-board documents. The causal pathways benefit people with a comprehensible representation approach to dise...

  • Article
  • Open Access
3 Citations
5,142 Views
13 Pages

A Causal Web between Chronotype and Metabolic Health Traits

  • John A. Williams,
  • Dominic Russ,
  • Laura Bravo-Merodio,
  • Victor Roth Cardoso,
  • Samantha C. Pendleton,
  • Furqan Aziz,
  • Animesh Acharjee and
  • Georgios V. Gkoutos

1 July 2021

Observational and experimental evidence has linked chronotype to both psychological and cardiometabolic traits. Recent Mendelian randomization (MR) studies have investigated direct links between chronotype and several of these traits, often in isolat...

  • Article
  • Open Access
5 Citations
4,993 Views
16 Pages

A Comprehensive Framework for Measuring the Immediate Impact of TV Advertisements: TV-Impact

  • Afra Arslan,
  • Koray Tecimer,
  • Hacer Turgut,
  • Ömür Bali,
  • Arda Yücel,
  • Gülfem Isiklar Alptekin and
  • Günce Keziban Orman

25 January 2024

Measuring the immediate impact of television advertisements (TV ads) on online traffic poses significant challenges in many aspects. Nonetheless, a comprehensive consideration is essential to fully grasp consumer reactions to TV ads. So far, the meas...

  • Proceeding Paper
  • Open Access
2 Citations
2,437 Views
9 Pages

The Circular Economy set a frame to govern sustainable growth. Laspias river basin (Thrace) is characterized by various land and water uses and pressures posed directly and/or indirectly on the riverine system which acts as a burdened receptor. The a...

  • Article
  • Open Access
6 Citations
2,877 Views
25 Pages

19 February 2025

The Internet of Things (IoT) is developing quickly, which has led to the development of new opportunities in many different fields. As the number of IoT devices continues to expand, particularly in transportation and healthcare, the need for efficien...

  • Article
  • Open Access
2,376 Views
20 Pages

27 February 2023

In the digital age, many sources of textual content are devoted to studying and expressing many sorts of relationships, including employer–employee, if–then, part–whole, product–producer, and cause–effect relations/causa...

  • Review
  • Open Access
7 Citations
7,124 Views
10 Pages

18 March 2016

Researchers have a long history in the conduct of evaluations of road safety countermeasures. However, despite the strengths of some evaluative road safety evaluations that align with previous and current thinking on program evaluation, few published...

  • Systematic Review
  • Open Access
4 Citations
3,625 Views
15 Pages

9 June 2023

There is increasing pressure on organisations and countries to manage the financial risks associated with climate change. This paper summarises research on climate change, credit risk and the associated losses, and specifically identifies methods tha...

  • Article
  • Open Access
11 Citations
5,430 Views
14 Pages

A recently emerged sustainable information society has ceased to be only a consumer and has become a web-based information source. Society’s online behaviour is tracked, recorded, processed, aggregated, and monetised. As a society, we are becom...

  • Article
  • Open Access
15 Citations
5,831 Views
24 Pages

Bibliometric Analysis of Granger Causality Studies

  • Weng Siew Lam,
  • Weng Hoe Lam,
  • Saiful Hafizah Jaaman and
  • Pei Fun Lee

7 April 2023

Granger causality provides a framework that uses predictability to identify causation between time series variables. This is important to policymakers for effective policy management and recommendations. Granger causality is recognized as the primary...

  • Perspective
  • Open Access
8 Citations
7,008 Views
13 Pages

Epistemology is the main branch of philosophy that studies the nature of knowledge, but how is new knowledge created? In this perspective article, I introduce a novel method of knowledge discovery that synthesizes online findings from current and pri...

  • Article
  • Open Access
1 Citations
2,781 Views
23 Pages

Harnessing Digital Marketing Analytics for Knowledge-Driven Digital Transformation in the Hospitality Industry

  • Dimitrios P. Reklitis,
  • Marina C. Terzi,
  • Damianos P. Sakas and
  • Panagiotis Reklitis

7 October 2025

In the digitally saturated hospitality environment, research on digital transformation remains dominated by macro-level adoption trends and user-generated content, while the potential of micro-level web-behavioural data remains largely untapped. Rece...

  • Article
  • Open Access
1,382 Views
32 Pages

4 November 2025

Considering the current prediction from the Food and Agriculture Organization, food production needs an increase of over 70 percent by 2050, and the agriculture sector requires a boost that is also obtained by integrating novelty technologies and met...

  • Proceeding Paper
  • Open Access
2,191 Views
26 Pages

Wage Rates and Job Requirements Prediction: An Application to Logistics Online Job Postings Using Search Tools and Web Scraping

  • Khoa Huu Dang Tran,
  • Huong Quynh Nguyen,
  • Hang My Hanh Le,
  • Lina Doan Tran and
  • Nhi To Yen Tran

This paper predicts offered wage rates and job requirements in the logistics industry by utilizing data from online job postings collected through two methods: search tools and web scraping. We apply conventional estimation techniques, such as ordina...

  • Systematic Review
  • Open Access
12 Citations
3,725 Views
16 Pages

The Nebulous Association between Cognitive Impairment and Falls in Older Adults: A Systematic Review of the Literature

  • Victoire Leroy,
  • Valérie Martinet,
  • Oumashankar Nunkessore,
  • Christel Dentel,
  • Hélène Durand,
  • David Mockler,
  • François Puisieux,
  • Bertrand Fougère and
  • Yaohua Chen

Background: In older people, dementia is a well-established risk factor for falls. However, the association and the causal relationship between falls and the earlier stages of cognitive impairment remains unclear. The purpose of the study was to revi...

  • Systematic Review
  • Open Access
2 Citations
2,564 Views
31 Pages

11 November 2024

Background/Objectives: Directed acyclic graphs (DAGs) inform the epidemiologic statistical modeling confounders to determine close to true causal relationships in a study context. They inform the inclusion of the predictive model variables that affec...

  • Article
  • Open Access
1 Citations
3,824 Views
22 Pages

A Versatile and Efficient Novel Approach for Mendelian Randomization Analysis with Application to Assess the Causal Effect of Fetal Hemoglobin on Anemia in Sickle Cell Anemia

  • Janaka S. S. Liyanage,
  • Jeremie H. Estepp,
  • Kumar Srivastava,
  • Sara R. Rashkin,
  • Vivien A. Sheehan,
  • Jane S. Hankins,
  • Clifford M. Takemoto,
  • Yun Li,
  • Yuehua Cui and
  • Guolian Kang
  • + 3 authors

12 October 2022

Mendelian randomization (MR) is increasingly employed as a technique to assess the causation of a risk factor on an outcome using observational data. The two-stage least-squares (2SLS) procedure is commonly used to examine the causation using genetic...

  • Article
  • Open Access
222 Views
17 Pages

10 February 2026

Root cause fault diagnostic reasoning is critical for ensuring the safety and reliability of airborne systems, where timely and accurate fault isolation can significantly reduce downtime and maintenance costs. However, the inherent complexity of faul...

  • Article
  • Open Access
475 Views
18 Pages

Provisioning Tacit Knowledge from a Human Resources Management Perspective: A Preliminary Causal Loop Diagram

  • Mario Aguilar-Fernández,
  • Graciela Salgado-Escobar,
  • Luvis P. León-Romero,
  • Brenda García-Jarquín and
  • Misaela Francisco-Márquez

8 January 2026

The aim of this research is to develop a preliminary causal loop diagram (PCLD) of the tacit knowledge (TK) provisioning in a firm, from the knowledge-based human resource management (KB-HRM) perspective, which facilitates understanding phenomenon dy...

  • Article
  • Open Access
6 Citations
4,222 Views
19 Pages

29 April 2022

This paper constructed a robust methodology to investigate the impact of news regarding macroeconomic policies on exchange rate fluctuations, and to examined the applicability of qualitative information alongside historical data to predict exchange r...

  • Article
  • Open Access
19 Citations
6,201 Views
7 Pages

Genetically Predicted Milk Intake and Risk of Neurodegenerative Diseases

  • Zhizhong Zhang,
  • Mengmeng Wang,
  • Shuai Yuan,
  • Susanna C. Larsson and
  • Xinfeng Liu

23 August 2021

Milk intake has been associated with risk of neurodegenerative diseases in observational studies. Nevertheless, whether the association is causal remains unknown. We adopted Mendelian randomization design to evaluate the potential causal association...

  • Article
  • Open Access
4 Citations
2,411 Views
22 Pages

26 March 2021

One of the main barriers when implementing social innovation deemed to be significant is the agency barrier. The purpose of this research is to diagnose the structurally conditioned and awareness agency barriers that occur during the implementation o...

  • Review
  • Open Access
26 Citations
11,189 Views
17 Pages

The Drivers-Pressures-State-Impact-Response Model to Structure Cause−Effect Relationships between Agriculture and Aquatic Ecosystems

  • Alexandre Troian,
  • Mário Conill Gomes,
  • Tales Tiecher,
  • Julio Berbel and
  • Carlos Gutiérrez-Martín

20 August 2021

Different segments of society have shown interest in understanding the effects of human activities on ecosystems. To this end, the aim of this article is to analyze the scientific literature on the application of the Drivers-Pressures-State-Impact-Re...

  • Review
  • Open Access
4 Citations
3,957 Views
12 Pages

Machine Learning Algorithms to Estimate Propensity Scores in Health Policy Evaluation: A Scoping Review

  • Luís Lourenço,
  • Luciano Weber,
  • Leandro Garcia,
  • Vinicius Ramos and
  • João Souza

(1) Background: Quasi-experimental design has been widely used in causal inference for health policy impact evaluation. However, due to the non-randomized treatment used, there is great potential for bias in the assessment of the results, which can b...

  • Review
  • Open Access
194 Views
20 Pages

Economic Evaluation of Multi-Objective Schistosomiasis Control Through Systemic Causality: Theoretical Advances and Governance Implications

  • Menghua Yu,
  • Xinyue Liu,
  • Na Shi,
  • Jiaqi Su,
  • Lefei Han,
  • Jian He,
  • Yaoqian Wang,
  • Suying Guo,
  • Wangping Deng and
  • Xiaoxi Zhang
  • + 6 authors

Schistosomiasis elimination is increasingly constrained less by the technical efficacy of single interventions than by systemic dynamics in coupled human–animal–environment settings, including nonlinear feedback, spatial heterogeneity, an...

  • Abstract
  • Open Access
1,048 Views
2 Pages

Vitamin D and Cardiovascular Disease Risk: Using Outcomes to Guide Future Nutrition Science

  • Diego Moretti,
  • Lorraine Brennan,
  • Mairead Kiely and
  • Jayne Woodside

Despite positive associations between micronutrient intake, status, and health outcomes, many randomized controlled trials (RCT) of vitamins are null. Standards to establish causality in biological systems include the Bradford Hill criteria, the expe...

  • Article
  • Open Access
809 Views
17 Pages

Exploring the Global and Regional Factors Influencing the Density of Trachurus japonicus in the South China Sea

  • Mingshuai Sun,
  • Yaquan Li,
  • Zuozhi Chen,
  • Youwei Xu,
  • Yutao Yang,
  • Yan Zhang,
  • Yalan Peng and
  • Haoda Zhou

21 July 2025

In this cross-disciplinary investigation, we uncover a suite of previously unexamined factors and their intricate interplay that hold causal relationships with the distribution of Trachurus japonicus in the northern reaches of the South China Sea, th...

  • Case Report
  • Open Access
767 Views
8 Pages

Prenatal Diagnosis of 6q Terminal Deletion Associated with Coffin–Siris Syndrome: Phenotypic Delineation and Review

  • Christian Peña-Padilla,
  • David Alejandro Martínez-Ceccopieri,
  • Evelin Montserrat García-Hernández,
  • Lucina Bobadilla-Morales and
  • Jorge Román Corona-Rivera

10 November 2025

Chromosome 6q deletion syndrome is a rare entity that has a highly variable clinical presentation and size of deletions. The most frequent manifestations of 6q terminal deletion are intellectual disability, facial dysmorphism, brain structural anomal...

  • Review
  • Open Access
23 Citations
5,225 Views
16 Pages

Radon Exposure and Neurodegenerative Disease

  • Silvia Gómez-Anca and
  • Juan Miguel Barros-Dios

Background: To carry out a systematic review of scientific literature about the association between radon exposure and neurodegenerative diseases. Methods: We performed a bibliographic search in the following databases: Pub med (Medline), Cochrane, B...

  • Systematic Review
  • Open Access
1,195 Views
15 Pages

4 December 2025

Background/Objectives: The association between gastroesophageal reflux disease (GERD) and extraesophageal malignancies remains unclear. This study aimed to systematically evaluate the relationship between GERD and these cancers. Methods: PubMed, Emba...

  • Article
  • Open Access
8 Citations
8,275 Views
35 Pages

Authors focus on ontology-based multidimensional data warehousing and mining methodologies, addressing various issues on organizing, reporting and documenting diabetic cases and their associated ailments, including causalities. Map and other diagnost...

  • Article
  • Open Access
10 Citations
5,587 Views
12 Pages

Background: Various health benefits from the ownership of companion dogs have been studied from a One Health perspective. However, the preventive effects on depression are unclear, with inconsistent results across studies. We hypothesized that hetero...

  • Systematic Review
  • Open Access
2,249 Views
10 Pages

The Association Between Chronic Obstructive Pulmonary Disease (COPD) and Migraine: Systematic Review and Meta-Analysis

  • Saleem Alshehri,
  • Maha Saad Zain Al-Abeden,
  • Mona Aldukain,
  • Ali Aldukain,
  • Dhai Almuteri,
  • Assal Hobani,
  • Abdulmalik Barakat and
  • Nora Alzoum

18 November 2024

Background/Objectives: Migraine and chronic obstructive pulmonary disease (COPD) are both common chronic conditions that may share underlying pathophysiological mechanisms despite presenting with distinct clinical features. Understanding the associat...

  • Systematic Review
  • Open Access
453 Views
12 Pages

Micro- and Nanoplastics as a Potential Risk Factor for Stroke: A Systematic Review

  • Jakub Kufel,
  • Miłosz Korbaś,
  • Julita Janiec,
  • Zofia Pankowska,
  • Marta Młynek,
  • Aleksandra Gaweł and
  • Adam Mitręga

14 February 2026

Environmental pollution with micro- and nanoplastics (MNPs) is an escalating global health concern. Despite growing evidence of MNPs’ presence in the human body, their impact on cerebrovascular diseases remains poorly understood. This study aim...

  • Review
  • Open Access
7 Citations
3,340 Views
26 Pages

Genomic and Precision Medicine Approaches in Atherosclerotic Cardiovascular Disease: From Risk Prediction to Therapy—A Review

  • Andreas Mitsis,
  • Elina Khattab,
  • Michaella Kyriakou,
  • Stefanos Sokratous,
  • Stefanos G. Sakellaropoulos,
  • Stergios Tzikas,
  • Nikolaos P. E. Kadogou and
  • George Kassimis

Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of global morbidity and mortality, prompting significant interest in individualized prevention and treatment strategies. This review synthesizes recent advances in genomic and pre...

  • Article
  • Open Access
9 Citations
6,490 Views
18 Pages

agReg-SNPdb: A Database of Regulatory SNPs for Agricultural Animal Species

  • Selina Klees,
  • Felix Heinrich,
  • Armin Otto Schmitt and
  • Mehmet Gültas

17 August 2021

Transcription factors (TFs) govern transcriptional gene regulation by specifically binding to short DNA motifs, known as transcription factor binding sites (TFBSs), in regulatory regions, such as promoters. Today, it is well known that single nucleot...

  • Article
  • Open Access
10 Citations
3,562 Views
7 Pages

Chronic Lumbar Pain and Insomnia in College-Aged Students

  • Katsumi Hamaoka,
  • Ryouta Ashizawa,
  • Mitsumasa Hida,
  • Ippei Suganuma and
  • Yoshinobu Yoshimoto

Insomnia in college students has a significant impact on academic performance and mental health (e.g., depression). Although the mechanisms underlying insomnia and chronic pain are becoming clearer, only a few studies on college students have examine...

  • Review
  • Open Access
22 Citations
4,264 Views
30 Pages

8 June 2020

Urban Sustainability and Smartness Understanding (USSU) can be defined by a group of sociopsychological determinants (such as awareness, perception, attitude and behavior) which shapes the relationship between human beings and the environment in whic...

  • Review
  • Open Access
58 Citations
15,262 Views
20 Pages

Advanced digital data-driven applications have evolved and significantly impacted the transportation sector in recent years. This systematic review examines natural language processing (NLP) approaches applied to aviation safety-related domains. The...

  • Article
  • Open Access
18 Citations
5,094 Views
15 Pages

Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents

  • Robert J. Reynolds,
  • Ryan T. Scott,
  • Russell T. Turner,
  • Urszula T. Iwaniec,
  • Mary L. Bouxsein,
  • Lauren M. Sanders and
  • Erik L. Antonsen

As part of the risk management plan for human system risks at the US National Aeronautics and Space Administration (NASA), the NASA Human Systems Risk Board uses causal diagrams (in the form of directed, acyclic graphs, or DAGs) to communicate the co...

  • Review
  • Open Access
6 Citations
7,671 Views
27 Pages

Hyperuricemia and Insulin Resistance: Interplay and Potential for Targeted Therapies

  • Opeyemi. O. Deji-Oloruntoba,
  • James Onoruoiza Balogun,
  • Taiwo. O. Elufioye and
  • Simeon Okechukwu Ajakwe

Hyperuricemia, defined as elevated serum uric acid (SUA) levels (>6.8 mg/dL), is traditionally linked to gout and nephrolithiasis but is increasingly implicated in insulin resistance (IR) and type 2 diabetes mellitus (T2DM). Epidemiological studie...

  • Systematic Review
  • Open Access
3 Citations
8,387 Views
15 Pages

Fibromyalgia and Skin Disorders: A Systematic Review

  • Martina D’Onghia,
  • Jacopo Ciaffi,
  • Laura Calabrese,
  • Linda Tognetti,
  • Elisa Cinotti,
  • Pietro Rubegni,
  • Bruno Frediani and
  • Francesco Ursini

27 July 2024

Background: Fibromyalgia is a complex multifaceted syndrome primarily characterised by chronic musculoskeletal pain, fatigue, and functional symptoms. Although FM is known to be associated with several comorbidities, the aim of this systematic review...

  • Review
  • Open Access
42 Citations
21,675 Views
12 Pages

Menstrual Cycle and Sport Injuries: A Systematic Review

  • Núria Martínez-Fortuny,
  • Alejandra Alonso-Calvete,
  • Iria Da Cuña-Carrera and
  • Rocío Abalo-Núñez

The presence of female athletes has only increased in recent years, as has the incidence of injuries in female sports activities. These injuries are conditioned by multiple factors, including hormonal agents. It is estimated that the menstrual cycle...

  • Article
  • Open Access
579 Views
32 Pages

1 February 2026

The main purpose of this study was to conduct a bibliometric analysis of scientific knowledge and trends in modern finance. To this end, the analysis was based on the keywords: “finance”, “automation”, and “ESG”. T...

  • Review
  • Open Access
578 Views
32 Pages

Pathogenetic Gut Microbiota in Aortic Diseases: Evidence and Mechanisms Across Aneurysm, Dissection, and Inflammatory Aortopathies

  • Leon Smółka,
  • Miłosz Strugała,
  • Karolina Blady,
  • Bartosz Pomianowski,
  • Karolina Kursa and
  • Agata Stanek

9 February 2026

Aortic diseases, including abdominal aortic aneurysm (AAA), thoracic aortic aneurysm (TAA), aortic dissection (AD), and Takayasu arteritis (TAK), are characterized by vascular remodeling and chronic immune–inflammatory activation, with AD often...

  • Systematic Review
  • Open Access
20 Citations
13,260 Views
11 Pages

Moral Distress and Emotional Exhaustion in Healthcare Professionals: A Systematic Review and Meta-Analysis

  • Alejandro Orgambídez,
  • Yolanda Borrego,
  • F. Javier Alcalde and
  • Auxiliadora Durán

12 February 2025

Background/Objectives: Moral distress is commonly experienced by healthcare professionals (i.e., nurses) as ethical conflict. Previous literature suggests that moral distress contributes to emotional exhaustion in these professionals. We aimed to syn...

  • Article
  • Open Access
36 Citations
7,015 Views
14 Pages

Association between Stigma and Anxiety, Depression, and Psychological Distress among Japanese Women Undergoing Infertility Treatment

  • Rie Yokota,
  • Tsuyoshi Okuhara,
  • Hiroko Okada,
  • Eiko Goto,
  • Keiko Sakakibara and
  • Takahiro Kiuchi

Japan has the highest number of cases of infertility treatment in the world. Studies have indicated that women undergoing infertility treatment feel stigmatized and suffer from psychological symptoms such as anxiety and depression. However, in Japan,...

  • Review
  • Open Access
773 Views
26 Pages

28 November 2025

This study maps how the scholarly literature examines government actions in relation to carbon emissions, rather than estimating the impact of specific policies. We conduct a bibliometric science-mapping using the Web of Science Core Collection (2010...

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