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6,026 Results Found

  • Article
  • Open Access
2 Citations
2,228 Views
12 Pages

5 January 2023

CO2 lasers have been generally used in oral soft-tissue surgery. Although an increase in power enhances the depth of ablation, the specific correlation between units of power and ablative depth has not been stated. This study aimed to explore ablativ...

  • Article
  • Open Access
13 Citations
3,332 Views
19 Pages

22 February 2022

The most widely used filler in EPDM-based thermal insulation materials is asbestos which is hazardous to health and environment. The main motivation of this study was to develop improved EPDM-based materials by partially or completely replacing asbes...

  • Article
  • Open Access
828 Views
19 Pages

Influence of Mullite and Halloysite Reinforcement on the Ablation Properties of an Epoxy Composite

  • Robert Szczepaniak,
  • Michał Piątkiewicz,
  • Dominik Gryc,
  • Paweł Przybyłek,
  • Grzegorz Woroniak and
  • Joanna Piotrowska-Woroniak

28 July 2025

This paper explores the impact of applying a powder additive in the form of halloysite and mullite on the thermal protection properties of a composite. The authors used CES R70 epoxy resin with CES H72 hardener, modified by varying the amount of powd...

  • Article
  • Open Access
27 Citations
5,315 Views
17 Pages

Synthesis of Silicon Hybrid Phenolic Resins with High Si-Content and Nanoscale Phase Separation Structure

  • Wenjie Yuan,
  • Fenghua Chen,
  • Shan Li,
  • Youpei Du,
  • Zhenhua Luo,
  • Yanan Sun,
  • Hao Li and
  • Tong Zhao

10 September 2020

In this paper, a set of silicon hybrid phenolic resins (SPF) with high Si-content were prepared by mixing phenolic resins with self-synthesized silicon resins. In order to obtain the nanoscale phase structure, condensation degree and the amount of Si...

  • Article
  • Open Access
13 Citations
3,193 Views
12 Pages

Improved Ablative Properties of Nanodiamond-Reinforced Carbon Fiber–Epoxy Matrix Composites

  • Umar Farooq,
  • Muhammad Umair Ali,
  • Shaik Javeed Hussain,
  • Muhammad Shakeel Ahmad,
  • Amad Zafar,
  • Usman Ghafoor and
  • Tayyab Subhani

22 June 2021

The influence of nanodiamonds (NDs) on the thermal and ablative performance of carbon-fiber-reinforced–epoxy matrix compositeswas explored. The ablative response of the composites with 0.2 wt% and 0.4 wt% NDs was studied through pre-and post-burning...

  • Article
  • Open Access
10 Citations
2,318 Views
13 Pages

Effects of MWCNTs on Char Layer Structure and Physicochemical Reaction in Ethylene Propylene Diene Monomer Insulators

  • Zhiheng Chen,
  • Shida Han,
  • Yuan Ji,
  • Hong Wu,
  • Shaoyun Guo,
  • Ning Yan and
  • Hongyan Li

26 July 2022

As one of the most promising ablative fillers, multi-walled carbon nanotubes (MWCNTs) have been used to improve the ablative resistance of Ethylene–Propylene–Diene Monomer (EPDM) insulators by facilitating the carbothermal reduction react...

  • Article
  • Open Access
4 Citations
2,177 Views
16 Pages

24 August 2023

Drug resistance to anticancer drugs is a serious complication in patients with cancer. Typically, drug resistance occurs due to amino acid substitutions (AAS) in drug target proteins. The study aimed at developing and validating a new approach to the...

  • Article
  • Open Access
28 Citations
6,245 Views
11 Pages

28 July 2021

In this paper, we are focusing on comparing results obtained for polymer elements manufactured with injection molding and additive manufacturing techniques. The analysis was performed for fused deposition modeling (FDM) and single screw injection mol...

  • Article
  • Open Access
16 Citations
4,235 Views
16 Pages

Enhancing Thermal Insulation of EPDM Ablators via Constructing Alternating Planar Architectures

  • Hongjian Qu,
  • Le Wang,
  • Kun Hui,
  • Cheng Bian,
  • Hongyan Li,
  • Yiwen Guan,
  • Tao Luan and
  • Ning Yan

12 April 2022

Ethylene–propylene–diene monomer (EPDM) composites were usually enhanced with ablative additives to protect solid rocket motor (SRMs) casings. However, the poor thermal insulation caused by the high thermal conductive ablative fillers can...

  • Article
  • Open Access
559 Views
18 Pages

Development and Characterization of New Ablative Materials Based on Polysiloxane Resin and Graphite Felt

  • George Pelin,
  • George-Cătălin Cristea,
  • Cristina-Elisabeta Pelin,
  • Maria Sonmez,
  • Alina Dragomirescu and
  • Sorina Ilina

24 December 2025

This study focused on the development of a new concept for ablative thermal protection material, using a relatively new polymer matrix based on polysiloxane resin, which exhibits high-performance thermal properties. As a reinforcing element, graphite...

  • Article
  • Open Access
19 Citations
4,093 Views
16 Pages

Development of a Mucoadhesive and In Situ Gelling Formulation Based on κ-Carrageenan for Application on Oral Mucosa and Esophagus Walls. I. A Functional In Vitro Characterization

  • Barbara Vigani,
  • Angela Faccendini,
  • Silvia Rossi,
  • Giuseppina Sandri,
  • Maria Cristina Bonferoni,
  • Matteo Gentile and
  • Franca Ferrari

12 February 2019

Oral mucositis and esophagitis represent the most frequent and clinically significant complications of cytoreductive chemotherapy and radiotherapy, which severely compromise the patient quality of life. The local application of polymeric gels could p...

  • Article
  • Open Access
11 Citations
5,462 Views
10 Pages

Floor antibacterial technology prevents the human body from cross-infection with bacterial diseases. The most commonly used approach to endow daily-used floors with antibacterial properties is to apply a thin film of antibacterial agents on the parqu...

  • Article
  • Open Access
4 Citations
2,362 Views
23 Pages

New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs

  • Thalia Delgado,
  • Denisa Veselá,
  • Hana Dostálová,
  • Vladimír Kryštof,
  • Veronika Vojáčková,
  • Radek Jorda,
  • Alejandro Castro,
  • Jeanluc Bertrand,
  • Gildardo Rivera and
  • Cristian O. Salas
  • + 3 authors

Bcr-Abl is an oncoprotein with aberrant tyrosine kinase activity involved in the progression of chronic myeloid leukemia (CML) and has been targeted by inhibitors such as imatinib and nilotinib. However, despite their efficacy in the treatment of CML...

  • Article
  • Open Access
9 Citations
4,159 Views
17 Pages

A New in Silico Antibody Similarity Measure Both Identifies Large Sets of Epitope Binders with Distinct CDRs and Accurately Predicts Off-Target Reactivity

  • Astrid Musnier,
  • Thomas Bourquard,
  • Amandine Vallet,
  • Laetitia Mathias,
  • Gilles Bruneau,
  • Mohammed Akli Ayoub,
  • Ophélie Travert,
  • Yannick Corde,
  • Nathalie Gallay and
  • Anne Poupon
  • + 5 authors

28 August 2022

Developing a therapeutic antibody is a long, tedious, and expensive process. Many obstacles need to be overcome, such as biophysical properties (issues of solubility, stability, weak production yields, etc.), as well as cross-reactivity and subsequen...

  • Article
  • Open Access
9 Citations
3,704 Views
24 Pages

Interpretation of Latent Codes in InfoGAN with SAR Images

  • Zhenpeng Feng,
  • Miloš Daković,
  • Hongbing Ji,
  • Xianda Zhou,
  • Mingzhe Zhu,
  • Xiyang Cui and
  • Ljubiša Stanković

24 February 2023

Generative adversarial networks (GANs) can synthesize abundant photo-realistic synthetic aperture radar (SAR) images. Some modified GANs (e.g., InfoGAN) are even able to edit specific properties of the synthesized images by introducing latent codes....

  • Article
  • Open Access
21 Citations
3,538 Views
15 Pages

9 July 2020

Ceramifiable ethylene propylene diene monomer (EPDM) composites with fiber network structures were prepared by using aramid fiber (AF), ammonium polyphosphate (APP), and silicate glass frits (SGF). The effect of AF on the curing characteristic of the...

  • Article
  • Open Access
1 Citations
1,301 Views
11 Pages

Nuclear density functional theory (DFT) is able to reproduce the saturation properties of nuclear matter, as well as properties of finite nuclei. Consequently, the DFT calculations are applicable to nuclei across a wide range of masses on the nuclear...

  • Article
  • Open Access
17 Citations
5,159 Views
23 Pages

On the Data-Driven Modeling of Reactive Extrusion

  • Ruben Ibañez,
  • Fanny Casteran,
  • Clara Argerich,
  • Chady Ghnatios,
  • Nicolas Hascoet,
  • Amine Ammar,
  • Philippe Cassagnau and
  • Francisco Chinesta

15 June 2020

This paper analyzes the ability of different machine learning techniques, able to operate in the low-data limit, for constructing the model linking material and process parameters with the properties and performances of parts obtained by reactive pol...

  • Article
  • Open Access
25 Citations
6,737 Views
20 Pages

24 February 2022

The rheological properties of blood depend highly on the properties of its red blood cells: concentration, membrane elasticity, and aggregation. These properties affect the viscosity of blood as well as its shear thinning behavior. Using an experimen...

  • Article
  • Open Access
39 Citations
6,427 Views
9 Pages

16 October 2020

Processing parameters in electrospinning allow us to control the properties of fibers on a molecular level and are able to tailor them for specific applications. In this study, we investigate how relative humidity (RH) affects the mechanical properti...

  • Article
  • Open Access
3 Citations
2,844 Views
20 Pages

Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets

  • Filippo Basagni,
  • Maria Luisa Di Paolo,
  • Giorgio Cozza,
  • Lisa Dalla Via,
  • Francesca Fagiani,
  • Cristina Lanni,
  • Michela Rosini and
  • Anna Minarini

4 November 2023

Oxidative stress and neuroinflammation play a pivotal role in triggering the neurodegenerative pathological cascades which characterize neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. In search for potential eff...

  • Article
  • Open Access
18 Citations
3,438 Views
18 Pages

Analyzing the Effect of Particle Shape on Deformation Mechanism during Cutting Simulation of SiC P/Al Composites

  • Jiakang Zhou,
  • Jieqiong Lin,
  • Mingming Lu,
  • Xian Jing,
  • Yubo Jin and
  • Dunlan Song

12 August 2021

To analyze the effect of particle shape on deformational behavior in the cutting simulation process for metal matrix composites (MMCs), two 2D mesoscopic-based finite element (FE) models reinforced with randomly distributed circular and irregular pol...

  • Article
  • Open Access
2 Citations
1,587 Views
14 Pages

Fasciola gigantica Recombinant Abelson Tyrosine Protein Kinase (rFgAbl) Regulates Various Functions of Buffalo Peripheral Blood Mononuclear Cells

  • Min Zhao,
  • Yu Zou,
  • Wanting Chen,
  • Dongqi Wu,
  • Chengjun Xian,
  • Haoqing Yang,
  • Jiacheng Tan,
  • Wenda Di,
  • Wende Wu and
  • Dongying Wang

10 January 2025

Fasciola gigantica can modulate host immune mechanisms through excretory–secretory products (ESP). As one of the components of ESP, it is unknown whether Abelson tyrosine protein kinase (Abl) is involved in parasite–host immune interaction. To invest...

  • Article
  • Open Access
29 Citations
5,112 Views
15 Pages

Rosmarinic Acid Attenuates Rotenone-Induced Neurotoxicity in SH-SY5Y Parkinson’s Disease Cell Model through Abl Inhibition

  • Xiao Han,
  • Bing Han,
  • Yue Zhao,
  • Gang Li,
  • Tian Wang,
  • Jie He,
  • Wenxiao Du,
  • Xiaolin Cao,
  • Jing Gan and
  • Wei Zheng
  • + 1 author

26 August 2022

Rosmarinic acid (RA) is a natural polyphenolic compound with antioxidative property. With the present study, we aimed to evaluate the neuroprotective role of RA on Parkinson’s disease using rotenone induced SH-SY5Y cell model of Parkinson&rsquo...

  • Article
  • Open Access
6 Citations
2,477 Views
21 Pages

Cr-Free Anticorrosive Primers for Marine Propeller Applications

  • Annie Wang,
  • Karnika De Silva,
  • Mark Jones and
  • Wei Gao

1 February 2024

Marine propellers work under severe service conditions, where they commonly suffer from mechanical, electrochemical, and biological corrosion damage. The major mechanical corrosion involves cavitation, erosion, and impingement corrosion. On the other...

  • Article
  • Open Access
19 Citations
10,585 Views
18 Pages

A Portable Sensing System for Electronic Tongue Operations

  • Karen Twomey,
  • Andreas Truemper and
  • Kilian Murphy

23 November 2006

A portable, low cost sensing system is described which interfaces to an electronictongue sensor. The sensor used is a voltammetric sensor which monitors electrochemicalreactions that occur in solutions. The sensor is able to test a range of liquids w...

  • Editorial
  • Open Access
3 Citations
4,430 Views
3 Pages

Advances in Natural Polymers: Extraction Methods and Applications

  • Cornelia Vasile,
  • Gabriel Aguirre-Álvarez and
  • Xiao-Feng Sun

1 July 2024

Biomass-based alternatives for the manufacturing of bioplastic materials are important aspects of a more sustainable future; their physicochemical properties need to be able to compete with the existing market to establish them as a viable alternativ...

  • Article
  • Open Access
8 Citations
6,829 Views
14 Pages

Assembly of 1D Granular Structures from Sulfonated Polystyrene Microparticles

  • Alexander Mikkelsen,
  • Ahmet Kertmen,
  • Khobaib Khobaib,
  • Michal Rajňák,
  • Juraj Kurimský and
  • Zbigniew Rozynek

21 October 2017

Being able to systematically modify the electric properties of nano- and microparticles opens up new possibilities for the bottom-up fabrication of advanced materials such as the fabrication of one-dimensional (1D) colloidal and granular materials. F...

  • Review
  • Open Access
273 Citations
25,116 Views
28 Pages

3 July 2018

Poly(3-hydroxybutyrate-co-3-hydroxyvalerate), PHBV, is a microbial biopolymer with excellent biocompatible and biodegradable properties that make it a potential candidate for substituting petroleum-derived polymers. However, it lacks mechanical stren...

  • Review
  • Open Access
5 Citations
5,909 Views
23 Pages

Chronic myeloid leukemia is a multistep, multi-lineage myeloproliferative disease that originates from a translocation event between chromosome 9 and chromosome 22 within the hematopoietic stem cell compartment. The resultant fusion protein BCR::ABL1...

  • Article
  • Open Access
2,316 Views
29 Pages

Use of a Yeast Protein-Based Intumescent Fire Retardant Bioadditive as Thermal and Mechanical Reinforcement for a PVAc Adhesive for Wood Products

  • Marcela Vidal-Vega,
  • Mario Núñez-Decap,
  • Diógenes Hernández-Espinoza and
  • Arturo Fernández-Pérez

15 February 2025

In this study, an intumescent fire retardant (IFR) bioadditive was designed based on a commercial Saccharomyces cerevisiae yeast protein matrix. Lignosulfonate was used as a cohesive reinforcement of its polymeric structure, along with magnesium hydr...

  • Article
  • Open Access
12 Citations
2,859 Views
28 Pages

Multifunctional Hydrogels Based on Cellulose and Modified Lignin for Advanced Wounds Management

  • Diana Elena Ciolacu,
  • Raluca Nicu,
  • Dana Mihaela Suflet,
  • Daniela Rusu,
  • Raluca Nicoleta Darie-Nita,
  • Natalia Simionescu,
  • Georgeta Cazacu and
  • Florin Ciolacu

Considering the complex process of wound healing, it is expected that an optimal wound dressing should be able to overcome the multiple obstacles that can be encountered in the wound healing process. An ideal dressing should be biocompatible, biodegr...

  • Proceeding Paper
  • Open Access
189 Views
6 Pages

13 November 2025

Acute lymphoblastic leukemia (ALL) is the most common cancer in childhood; 30–50% of its cases are caused by the BCR-ABL1 fusion gene as a driver oncogene. In this research work, a study of the cytotoxic properties of phthalimido-1,3-thiazole d...

  • Article
  • Open Access
20 Citations
4,414 Views
26 Pages

Synthesis, Biological Activity, and Molecular Modelling Studies of Naphthoquinone Derivatives as Promising Anticancer Candidates Targeting COX-2

  • Povilas Kavaliauskas,
  • Felipe Stambuk Opazo,
  • Waldo Acevedo,
  • Ruta Petraitiene,
  • Birutė Grybaitė,
  • Kazimieras Anusevičius,
  • Vytautas Mickevičius,
  • Sergey Belyakov and
  • Vidmantas Petraitis

27 April 2022

Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-associated mortalities worldwide. Therefore, it is crucial to develop a novel therapeutic option targeting localized and metastatic NSCLC. In this paper, we describe the synthesis a...

  • Article
  • Open Access
4 Citations
2,610 Views
25 Pages

21 January 2025

In this paper, magnetic permeability sensors able to perform structural health monitoring of magnetic steels, by means of determining residual strain and stress amplitude and gradient distribution, responsible for crack initiation, are presented. The...

  • Article
  • Open Access
80 Citations
11,046 Views
20 Pages

Lactic Fermentation as an Efficient Tool to Enhance the Antioxidant Activity of Tropical Fruit Juices and Teas

  • Amandine Fessard,
  • Ashish Kapoor,
  • Jessica Patche,
  • Sophie Assemat,
  • Mathilde Hoarau,
  • Emmanuel Bourdon,
  • Theeshan Bahorun and
  • Fabienne Remize

Tropical fruits like pineapple, papaya, mango, and beverages such as green or black teas, represent an underestimated source of antioxidants that could exert health-promoting properties. Most food processing technologies applied to fruit beverages or...

  • Review
  • Open Access
104 Citations
8,169 Views
23 Pages

Graphene Optical Biosensors

  • Zongwen Li,
  • Wenfei Zhang and
  • Fei Xing

Graphene shows great potential in biosensing owing to its extraordinary optical, electrical and physical properties. In particular, graphene possesses unique optical properties, such as broadband and tunable absorption, and strong polarization-depend...

  • Article
  • Open Access
34 Citations
4,284 Views
16 Pages

Development of a Mucoadhesive and an in Situ Gelling Formulation Based on κ-Carrageenan for Application on Oral Mucosa and Esophagus Walls. II. Loading of a Bioactive Hydroalcoholic Extract

  • Barbara Vigani,
  • Silvia Rossi,
  • Matteo Gentile,
  • Giuseppina Sandri,
  • Maria Cristina Bonferoni,
  • Valeria Cavalloro,
  • Emanuela Martino,
  • Simona Collina and
  • Franca Ferrari

5 March 2019

The aim of the present work was to load a Hibiscus sabdariffa (HS) hydroalcoholic extract into in situ gelling formulations for the treatment of oral mucositis and esophagitis. Such formulations, selected as the most promising options in a previous w...

  • Article
  • Open Access
22 Citations
4,762 Views
18 Pages

An In Situ Gelling System for the Local Treatment of Inflammatory Bowel Disease (IBD). The Loading of Maqui (Aristotelia chilensis) Berry Extract as an Antioxidant and Anti-Inflammatory Agent

  • Marika Tenci,
  • Silvia Rossi,
  • Valentina Giannino,
  • Barbara Vigani,
  • Giuseppina Sandri,
  • Maria Cristina Bonferoni,
  • Maria Daglia,
  • Luigi Maria Longo,
  • Cristina Macelloni and
  • Franca Ferrari

The aim of the present work was the development of an innovative in situ gelling system, to be applied on the mucosa of the distal colon via rectal route. The system consisted of three polymers having different functions: gellan (GG), able to jellify...

  • Article
  • Open Access
13 Citations
4,644 Views
15 Pages

Optimizing Viscoelastic Properties of Rubber Compounds for Ballistic Applications

  • Janis Karl,
  • Franziska Kirsch,
  • Norbert Faderl,
  • Leonhard Perko and
  • Teresa Fras

5 November 2020

Using interlayers of rubber adds a positive effect to the synergy of disruptor–absorber armors. Emerging from its viscoelasticity the material is able to transform mechanical stress into heat. The dynamic mechanical properties of elastomers dep...

  • Review
  • Open Access
4 Citations
3,489 Views
20 Pages

14 September 2021

Shape-from-Focus (SFF) methods have been developed for about twenty years. They able to obtain the shape of 3D objects from a series of partially focused images. The plane to which the microscope or camera is focused intersects the 3D object in a con...

  • Article
  • Open Access
65 Citations
6,189 Views
22 Pages

19 November 2020

In metal forming, the plastic behavior of metallic alloys is directly related to their formability, and it has been traditionally characterized by simplified models of the flow curves, especially in the analysis by finite element simulation and analy...

  • Article
  • Open Access
15 Citations
4,030 Views
28 Pages

Optimization of an Injectable, Resorbable, Bioactive Cement Able to Release the Anti-Osteoclastogenic Biomolecule ICOS-Fc for the Treatment of Osteoporotic Vertebral Compression Fractures

  • Federica Banche-Niclot,
  • Ilaria Corvaglia,
  • Caterina Cavalera,
  • Elena Boggio,
  • Casimiro Luca Gigliotti,
  • Umberto Dianzani,
  • Antzela Tzagiollari,
  • Nicholas Dunne,
  • Antonio Manca and
  • Chiara Vitale-Brovarone
  • + 1 author

2 January 2023

Vertebral compression fractures are typical of osteoporosis and their treatment can require the injection of a cement through a minimally invasive procedure to restore vertebral body height. This study reports the development of an injectable calcium...

  • Abstract
  • Open Access
1,236 Views
2 Pages

The Role of Boron on the Microstructure and Properties of a Ni-Si-B Cast Alloy

  • Gonçalo M. Gorito,
  • Manuel F. Vieira and
  • Laura M. M. Ribeiro

Ni-Si-B alloys stand out for their high corrosion resistance and mechanical properties at high temperatures, able them to compete with austenitic stainless steels for applications in aerospace, aeronautical, nuclear, chemical, automotive, as well as...

  • Article
  • Open Access
12 Citations
9,668 Views
17 Pages

2 November 2016

Vitamin C is widely use in cosmetics and pharmaceutics products for its active properties. However ascorbic acid shows unfavourable chemical instability such as oxidation leading to formulation problems. Therefore, carriers, such as micro- and nanopa...

  • Article
  • Open Access
2 Citations
2,862 Views
28 Pages

27 May 2022

A new scheme called AUSMAS (Advection Upstream Splitting Method for All Speeds) is proposed for both high speed and low speed simulation cases. For the cases of low speed, it controls the checkerboard decoupling by keeping the coefficient of the pres...

  • Article
  • Open Access
8 Citations
2,948 Views
23 Pages

12 September 2024

Additive manufacturing has profoundly influenced the aerospace industry since its inception, offering unmatched design freedom, cost reduction, rapid prototyping, and enhanced supply-chain efficiency. High-performance polymers like ULTEM™ and P...

  • Article
  • Open Access
7 Citations
3,161 Views
10 Pages

Action of Extracellular Proteases of Aspergillus flavus and Aspergillus ochraceus Micromycetes on Plasma Hemostasis Proteins

  • Alexander A. Osmolovskiy,
  • Laura Schmidt,
  • Anastasia V. Orekhova,
  • Sergey K. Komarevtsev,
  • Valeriana G. Kreyer,
  • Sergey V. Shabunin and
  • Nikolay S. Egorov

2 August 2021

In this study, we investigated the properties of proteolytic enzymes of two species of Aspergillus, Aspergillus flavus 1 (with a high degree of pathogenicity) and Aspergillus ochraceus L-1 (a conditional pathogen), and their effects on various compon...

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