Acarus siro L. and Tyrophagus putrescentiae (Schrank) (Sarcoptiformes: Acaridae) are cosmopolitan mite species in food storage and processing environments, infesting a wide variety of commodities. In the current study, the diatomaceous earths (DEs) I...
Stainless-steel fibre hybrid spun yarns are becoming increasingly popular due to their wide range of applications. In this aspect, the cost-effective and scalable processing of such yarns is highly important. Stainless-steel staple fibres are relativ...
The dynamic regulation of fiber stress distribution in the yarn-forming triangle area is critical for controlling variable composite yarn structures, including siro and sirofil composite yarns. In this study, comparison analyses of the variable geome...
Background/Objectives: The concurrent circulation of SARS-CoV-2 with influenza A and B viruses and respiratory syncytial virus (RSV) represents a new diagnostic challenge in the post-COVID-19 area, especially considering that these infections have ov...
This study aimed to evaluate the antibacterial effect of three final irrigation protocols and to compare their ability to remove the smear layer and debris from the root canal. Methods: Sixty-three single-rooted human teeth were inoculated with Enter...
Cheyletus malaccensis Oudemans and Cheyletus eruditus (Schrank) are predators of stored-grain pests in China. The psocid Liposcelis bostrychophila Badonnel is prone to outbreaks in depots. To assess the potential of large-scale breeding with Acarus s...
The Maasai Mara and the wider Mau River Basin in East Africa provide fundamental ecosystem services that support people, wildlife, livestock and agriculture. The historical indigenous land use of the Mara and wider Mau basin was wildlife conservation...
In the original article [...]
Bioprospecting of novel antibiotics has been the conventional norm of research fostered by researchers worldwide to combat drug resistance. With the exhaustion of incessant leads, the search for new chemical entities moves into uncharted territories...
The reuse and recycling of critical raw materials is limited, as waste electrical and electronic recycling focuses on base and precious metals, and device component reuse is in its infancy. To help to address this issue this paper provides the concep...
Objective: Transcatheter aortic valve implant (TAVI) is the gold standard for the high-surgical-risk group of patients with aortic valve disease and it is an alternative to surgery in patients at intermediate risk. Lethal complications can occur, and...
Studies on animals and humans have amply demonstrated the therapeutic efficacy of botulinum neurotoxins (BoNTs) in many pathologies [...]
Considering the high vulnerability of existing masonry buildings, which often have strategic or cultural value, professionals and specialized engineers are frequently required to model complex historical buildings. The approaches proposed by National...
Background. The in-hospital reduction in low-density lipoprotein cholesterol (LDL-C) levels following acute coronary syndrome (ACS) is recommended in the current clinical guidelines. However, the efficacy of proprotein convertase subtilisin–kex...
Background: The present work aimed to determine whether a relationship exists between inflammatory parameters and the development of vasospasm (VS) and Takotsubo cardiomyopathy (TTC), as well as clinical outcome, in patients suffering from spontaneou...
Microbial secondary metabolites are an important source of antibiotics currently available for combating drug-resistant pathogens. These important secondary metabolites are produced by various microorganisms, including Actinobacteria. Actinobacteria...
In recent years, numerous studies have highlighted the significant use of botulinum neurotoxins (BoNTs) in the human therapy of various motor and autonomic disorders. The therapeutic action is exerted with the selective cleavage of specific sites of...
Botulinum neurotoxins (BoNTs) are toxins produced by the bacteria Clostridium botulinum, the causing agent for botulism, in different serotypes, seven of which (A–G) are well characterized, while others, such as H or FA, are still debated. BoNT...
Conduction system pacing (CSP) encompassing His bundle (HBP) and left bundle branch area pacing (LBBAP) is gaining increasing attention in the electrophysiology community. These relatively novel physiological pacing modalities have the potential to o...
Background: Coronavirus Disease 2019 (COVID-19) is the main discussed topic worldwide in 2020 and at the beginning of the Italian epidemic, scientists tried to understand the virus diffusion and the epidemic curve of positive cases with controversial...
Botulinum neurotoxin type A (BoNT/A) is a major therapeutic agent that has been proven to be a successful treatment for different neurological disorders, with emerging novel therapeutic indications each year. BoNT/A exerts its action by blocking SNAR...
Botulinum toxins (BoNTs) are a true wonder of nature [...]
Xeomin® is a commercial formulation of botulinum neurotoxin type A (BoNT/A) clinically authorized for treating neurological disorders, such as blepharospasm, cervical dystonia, limb spasticity, and sialorrhea. We have previously demonstrated that...
The action of botulinum neurotoxins (BoNTs) at the neuromuscular junction has been extensively investigated and knowledge gained in this field laid the foundation for the use of BoNTs in human pathologies characterized by excessive muscle contraction...
Clinical use of neurotoxins from Clostridium botulinum is well established and is continuously expanding, including in treatment of pain conditions. Background: The serotype A (BoNT/A) has been widely investigated, and current data demonstrate that i...
Botulinum neurotoxin A (BoNT/A) is a toxin produced by the naturally-occurring Clostridium botulinum that causes botulism. The potential of BoNT/A as a useful medical intervention was discovered by scientists developing a vaccine to protect against b...
The development of artillery in Europe at the end of the Middle Ages brought a necessary change in military architecture. This change was a radical rethinking of the entire geometry and architectural design of city walls which required an increase in...
Botulinum neurotoxins (BoNTs) are potent inhibitors of synaptic vesicle fusion and transmitter release. The natural target of BoNTs is the peripheral neuromuscular junction (NMJ) where, by blocking the release of acetylcholine (ACh), they functionall...
DPY19L3 has been identified as a C-mannosyltransferase for thrombospondin type-1 repeat domain-containing proteins. In this study, we focused on the role of DPY19L3 in the myogenic differentiation of C2C12 mouse myoblast cells. We carried out DPY19L3...
Ecological surveys of living things based on DNAs from environmental samples are attractive. However, despite simplicity of water sampling from the target environment, it is still necessary to transport the samples to the laboratory for DNA analysis...
Background: The inhibition of PCSK9 lowered LDL cholesterol levels, reducing the risk of cardiovascular events. However, the effect on patients who have undergone surgical myocardial revascularization has not yet been evaluated. Methods: From January...
Syntheticdata generation methods are used to transform the original data into privacy-compliant synthetic copies (twin data). With our proposed approach, synthetic data can be simulated in the same size as the input data or in any size, and in the ca...
Clostridium botulinum strains produce seven antigenically distinct botulinum neurotoxins (BoNTs), referred to as serotypes A–G, and a hybrid toxin called F/A [...]
Botulinum neurotoxins (BoNTs) are known to inhibit synaptic transmission by targeting SNARE proteins, but their selectivity toward central excitatory and inhibitory pathways is not yet fully understood. In this study, the interaction of serotypes A (...
A numerical model based on the heuristic molecule (HM) concept is proposed to evaluate the in-plane and Coulomb-like shear behavior of masonry panels. The model extends the well-established Rigid-Body-Spring Model (RBSM), which demonstrated good effe...
Background: COPD patients may be prone to cerebral small vessel disease resulting in perivascular white matter lesions and consequent cognitive decline. The pathophysiological background of these observations is not completely understood. It is hypot...
Point-of-care ultrasonography (POCUS) has become an integral part of intensive and emergency care. Despite the widespread use and availability of multipurpose ultrasound devices, the regular assessment of intracranial circulatory conditions has not b...
Background/Objectives: Combining calcineurin inhibitors (CNIs) with mTOR inhibitors has been explored to reduce CNI exposure. However, the safety of this early conversion approach remains uncertain, and the optimal therapeutic targets for tacrolimus...
Chlorantraniliprole is an effective pesticide against a plethora of pests, but its efficacy against stored-product pests is very poorly explored. In this study we treated concrete surfaces with four different doses of chlorantraniliprole (0.01, 0.05,...
This work presents a novel self-organizing control method for mega constellations to meet the continuous Earth observation requirements. In order to decrease the TT&C pressure caused by numerous satellites, constellation satellites are not contro...
Most fungal species are commensals and non-pathogenic to plants, humans, or animals. However, several species of the Alternaria, Aspergillus, Trichophyton, and Microsporum genera are common causes of disease, even for immunocompetent individuals. Bes...
Canine atopic dermatitis (AD) is a chronic allergic skin disease in which various immunological markers have been investigated. While peripheral eosinophil counts, serum allergen-specific immunoglobulin E (IgE), and cytokines have each been evaluated...
Biogas production within cooperatives and energy clusters that include both food businesses and biogas plants seems to be a good way to both improve financial health and increase energy self-sufficiency. The paper assesses the financial health of mor...
Cheyletus malaccensis Oudemans is a predatory mite inhabiting grain depots in China. The relationship between temperature and the population growth rate of C. malaccensis is useful for predicting its population dynamics. Age-stage, two-sex life table...
11 October 2021
The northern Italian region of Lombardy has been severely affected by the COVID-19 pandemic since its arrival in Europe. However, there are only a few published studies of the possible influence of social and cultural factors on its prevalence in the...
The study presents a didactic experience for the deep refurbishment and the revitalization of the San Siro neighborhood in Milan (Italy). The public housing is a significative example of the 20th-century architecture (also named “Italian Modern...
Before insects can be used widely as an alternative source of dietary protein, their allerginicity should be investigated. Therefore, the aim of our study was to assess the potential adverse reactions of the immune system of dogs against Tenebrio mol...
This study conducted a multi-directional evaluation of the chemical potential and biological properties of selected European fungal species of the genus Phellinus. We investigated 30 samples belonging to 22 Phellinus species. Fruiting bodies were col...
Urban transportation systems encounter distinctive challenges during planned major city events characterized by large gatherings that disrupt traffic patterns. The surge in private car usage for attending such events leads to a sudden increase in tra...
Sitophilus oryzae, Tribolium castaneum, Tribolium confusum, Oryzaephilus surinamensis, Rhyzopertha dominica, Tenebrio molitor, Trogoderma granarium, Acarus siro, and Alphitobius diaperinus represent significant arthropod stored-product pests worldwid...
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