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15,341 Results Found

  • Article
  • Open Access
11 Citations
5,673 Views
13 Pages

QoS-Based DWBA Algorithm for NG-EPON

  • Ammar Rafiq and
  • Muhammad Faisal Hayat

The next-generation Ethernet passive optical network (NG-EPON) is basically classified into two architectures on the basis of the wavelength sharing by the optical network units (ONUs). The single scheduling domain (SSD) and multi-scheduling domain (...

  • Article
  • Open Access
9 Citations
3,173 Views
16 Pages

28 February 2021

The structure, stability, and bonding character of fifteen (Ng-H-Ng)+ and (Ng-H-Ng’)+ (Ng, Ng’ = He-Xe) compounds were explored by theoretical calculations performed at the coupled cluster level of theory. The nature of the stabilizing interactions w...

  • Article
  • Open Access
8 Citations
6,433 Views
20 Pages

21 March 2014

The primary design goal of (r)evolutionary NG-PON1&2 was the provisioning of an ever increasing capacity to cope with video-dominated traffic and handle the explosion of mobile data traffic by means of offloading. Recently, however, questions on...

  • Article
  • Open Access
54 Citations
9,300 Views
19 Pages

Life Cycle GHG of NG-Based Fuel and Electric Vehicle in China

  • Xunmin Ou,
  • Xiliang Zhang,
  • Xu Zhang and
  • Qian Zhang

22 May 2013

This paper compares the greenhouse gas (GHG) emissions of natural gas (NG)- based fuels to the GHG emissions of electric vehicles (EVs) powered with NG-to-electricity in China. A life-cycle model is used to account for full fuel cycle and use-phase...

  • Article
  • Open Access
929 Views
11 Pages

Evaluation of the NG-Test CARBA 5 for Rapid Detection of Carbapenemases in Clinical Isolates of Klebsiella pneumoniae

  • Bojan Rakonjac,
  • Momčilo Djurić,
  • Danijela Djurić-Petković,
  • Jelena Dabić,
  • Marko Simonović,
  • Marija Milić and
  • Aleksandra Arsović

Background: Carbapenem-resistant Klebsiella pneumoniae (CRKp) is a critical global health threat due to its multidrug resistance, primarily driven by carbapenemase production. Rapid and accurate detection of carbapenemases is essential for effective...

  • Article
  • Open Access
13 Citations
3,062 Views
17 Pages

CK2 Activity Mediates the Aggressive Molecular Signature of Glioblastoma Multiforme by Inducing Nerve/Glial Antigen (NG)2 Expression

  • Beate M. Schmitt,
  • Anne S. Boewe,
  • Claudia Götz,
  • Stephan E. Philipp,
  • Steffi Urbschat,
  • Joachim Oertel,
  • Michael D. Menger,
  • Matthias W. Laschke and
  • Emmanuel Ampofo

2 April 2021

Nerve/glial antigen (NG)2 expression crucially determines the aggressiveness of glioblastoma multiforme (GBM). Recent evidence suggests that protein kinase CK2 regulates NG2 expression. Therefore, we investigated in the present study whether CK2 inhi...

  • Article
  • Open Access
1 Citations
1,965 Views
20 Pages

Enhancing Tactile Internet Reliability: AI-Driven Resilience in NG-EPON Networks

  • Andrew Tanny Liem,
  • I-Shyan Hwang,
  • Razat Kharga and
  • Chin-Hung Teng

26 September 2024

To guarantee the reliability of Tactile Internet (TI) applications such as telesurgery, which demand extremely high reliability and are experiencing rapid expansion, we propose a novel smart resilience mechanism for Next-Generation Ethernet Passive O...

  • Article
  • Open Access
9 Citations
3,765 Views
19 Pages

Protein Kinase CK2 Regulates Nerve/Glial Antigen (NG)2-Mediated Angiogenic Activity of Human Pericytes

  • Beate M. Schmitt,
  • Anne S. Boewe,
  • Vivien Becker,
  • Lisa Nalbach,
  • Yuan Gu,
  • Claudia Götz,
  • Michael D. Menger,
  • Matthias W. Laschke and
  • Emmanuel Ampofo

25 June 2020

Protein kinase CK2 is a crucial regulator of endothelial cell proliferation, migration and sprouting during angiogenesis. However, it is still unknown whether this kinase additionally affects the angiogenic activity of other vessel-associated cells....

  • Article
  • Open Access
15 Citations
3,520 Views
16 Pages

Evaluation of Simulated AVIRIS-NG Imagery Using a Spectral Reconstruction Method for the Retrieval of Leaf Chlorophyll Content

  • Bhagyashree Verma,
  • Rajendra Prasad,
  • Prashant K. Srivastava,
  • Prachi Singh,
  • Anushree Badola and
  • Jyoti Sharma

25 July 2022

The leaf chlorophyll content (LCC) is a vital parameter that indicates plant production, stress, and nutrient availability. It is critically needed for precision farming. There are several multispectral images available freely, but their applicabilit...

  • Article
  • Open Access
793 Views
22 Pages

Performance Evaluation of Closed Crankcase Ventilation System in an Industrial NG Engine

  • Arturo Quintero Castillo,
  • Juan Felipe Rodríguez,
  • Bret Windom and
  • Daniel B. Olsen

19 August 2025

This study evaluates the impact of a Closed Crankcase Ventilation (CCV) system on Caterpillar G3516J NG engine performance and emissions, focusing on engine performance, methane (CH4) emissions, oil consumption, and oil particle size distribution. Th...

  • Article
  • Open Access
27 Citations
4,971 Views
26 Pages

Potentials of Airborne Hyperspectral AVIRIS-NG Data in the Exploration of Base Metal Deposit—A Study in the Parts of Bhilwara, Rajasthan

  • Arindam Guha,
  • Uday Kumar Ghosh,
  • Joyasree Sinha,
  • Amin Beiranvand Pour,
  • Ratnakar Bhaisal,
  • Snehamoy Chatterjee,
  • Nikhil Kumar Baranval,
  • Nisha Rani,
  • K. Vinod Kumar and
  • Pamaraju V. N. Rao

27 May 2021

In this study, we have processed the spectral bands of airborne hyperspectral data of Advanced Visible Infrared Imaging Spectrometer-Next Generation (AVIRIS-NG) data for delineating the surface signatures associated with the base metal mineralization...

  • Proceeding Paper
  • Open Access
1,814 Views
7 Pages

AVIRIS-NG Data for Geological Applications in Southeastern Parts of Aravalli Fold Belt, Rajasthan

  • Sameeksha Mishra,
  • Shovan L. Chattoraj,
  • Alen Benny,
  • Richa U. Sharma and
  • P. K. Champati Ray

Advanced techniques using high resolution hyperspectral remote sensing data has recently evolved as an emerging tool with potential to aid mineral exploration. In this study, pertinently, five mosaicked scenes of Airborne Visible InfraRed Imaging Spe...

  • Article
  • Open Access
7 Citations
7,210 Views
21 Pages

12 August 2017

A comparison between efforts to detect methane anomalies by a simple band ratio approach from the Airborne Visual Infrared Imaging Spectrometer-Classic (AVIRIS-C) data for the Kern Front oil field, Central California, and the Coal Oil Point marine hy...

  • Article
  • Open Access
18 Citations
19,203 Views
18 Pages

Activation Process of ONU in EPON/GPON/XG-PON/NG-PON2 Networks

  • Tomas Horvath,
  • Petr Munster,
  • Vaclav Oujezsky and
  • Josef Vojtech

16 October 2018

This article presents a numerical implementation of the activation process for gigabit and 10 gigabit next generation and Ethernet passive optical networks. The specifications are completely different because GPON, XG-PON and NG-PON2 were developed b...

  • Article
  • Open Access
15 Citations
6,388 Views
15 Pages

Improved Boreal Forest Wildfire Fuel Type Mapping in Interior Alaska Using AVIRIS-NG Hyperspectral Data

  • Christopher William Smith,
  • Santosh K. Panda,
  • Uma Suren Bhatt and
  • Franz J. Meyer

27 February 2021

In Alaska the current wildfire fuel map products were generated from low spatial (30 m) and spectral resolution (11 bands) Landsat 8 satellite imagery which resulted in map products that not only lack the granularity but also have insufficient accura...

  • Article
  • Open Access
56 Citations
8,239 Views
17 Pages

Species-Level Classification and Mapping of a Mangrove Forest Using Random Forest—Utilisation of AVIRIS-NG and Sentinel Data

  • Mukunda Dev Behera,
  • Surbhi Barnwal,
  • Somnath Paramanik,
  • Pulakesh Das,
  • Bimal Kumar Bhattyacharya,
  • Buddolla Jagadish,
  • Parth S. Roy,
  • Sujit Madhab Ghosh and
  • Soumit Kumar Behera

21 May 2021

Although studies on species-level classification and mapping using multisource data and machine learning approaches are plenty, the use of data with ideal placement of central wavelength and bandwidth at appropriate spatial resolution, for the classi...

  • Article
  • Open Access
10 Citations
3,418 Views
15 Pages

Molecular Typing of Neisseria gonorrhoeae Clinical Isolates in Russia, 2018–2019: A Link Between penA Alleles and NG-MAST Types

  • Ilya Kandinov,
  • Ekaterina Dementieva,
  • Dmitry Kravtsov,
  • Alexander Chestkov,
  • Alexey Kubanov,
  • Victoria Solomka,
  • Dmitry Deryabin,
  • Dmitry Gryadunov and
  • Boris Shaskolskiy

12 November 2020

This work aimed to study penA gene polymorphisms in clinical isolates of Neisseria gonorrhoeae collected in Russia in 2018–2019 and the contribution of the penA allele type to susceptibility to β-lactam antibiotics. A total of 182 isolates...

  • Communication
  • Open Access
1,173 Views
8 Pages

2 September 2025

Background: Bone tissue decalcification is essential for histopathological evaluation, but conventional methods using inorganic acids degrade nucleic acids, limiting molecular testing. EDTA is known to better preserve DNA, but its suitability for nex...

  • Article
  • Open Access
7 Citations
1,977 Views
22 Pages

Assessing Greenhouse Gas Monitoring Capabilities Using SolAtmos End-to-End Simulator: Application to the Uvsq-Sat NG Mission

  • Cannelle Clavier,
  • Mustapha Meftah,
  • Alain Sarkissian,
  • Frédéric Romand,
  • Odile Hembise Fanton d’Andon,
  • Antoine Mangin,
  • Slimane Bekki,
  • Pierre-Richard Dahoo,
  • Patrick Galopeau and
  • Franck Lefèvre
  • + 2 authors

18 April 2024

Monitoring atmospheric concentrations of greenhouse gases (GHGs) like carbon dioxide and methane in near real time and with good spatial resolution is crucial for enhancing our understanding of the sources and sinks of these gases. A novel approach c...

  • Communication
  • Open Access
50 Citations
6,421 Views
9 Pages

Expanding the CRISPR Toolbox in P. patens Using SpCas9-NG Variant and Application for Gene and Base Editing in Solanaceae Crops

  • Florian Veillet,
  • Laura Perrot,
  • Anouchka Guyon-Debast,
  • Marie-Paule Kermarrec,
  • Laura Chauvin,
  • Jean-Eric Chauvin,
  • Jean-Luc Gallois,
  • Marianne Mazier and
  • Fabien Nogué

4 February 2020

Genome editing has become a major tool for both functional studies and plant breeding in several species. Besides generating knockouts through the classical CRISPR-Cas9 system, recent development of CRISPR base editing holds great and exciting opport...

  • Article
  • Open Access
7 Citations
2,939 Views
15 Pages

Emergence of Azithromycin-Resistant Neisseria gonorrhoeae Isolates Belonging to the NG-MAST Genogroup 12302 in Russia

  • Ilya Kandinov,
  • Ekaterina Dementieva,
  • Marina Filippova,
  • Alexandra Vinokurova,
  • Sofya Gorshkova,
  • Alexey Kubanov,
  • Victoria Solomka,
  • Julia Shagabieva,
  • Dmitry Deryabin and
  • Boris Shaskolskiy
  • + 1 author

The goal of this work was to determine the factors affecting the emergence of azithromycin-resistant Neisseria gonorrhoeae isolates in Russia, where azithromycin was never recommended for the treatment of gonococcal infections. Clinical N. gonorrhoea...

  • Article
  • Open Access
21 Citations
9,871 Views
17 Pages

CSI NGS Portal: An Online Platform for Automated NGS Data Analysis and Sharing

  • Omer An,
  • Kar-Tong Tan,
  • Ying Li,
  • Jia Li,
  • Chan-Shuo Wu,
  • Bin Zhang,
  • Leilei Chen and
  • Henry Yang

Next-generation sequencing (NGS) has been a widely-used technology in biomedical research for understanding the role of molecular genetics of cells in health and disease. A variety of computational tools have been developed to analyse the vastly grow...

  • Article
  • Open Access
3 Citations
1,373 Views
20 Pages

NiFe2O4 and TiO2 are widely studied for photoelectrochemical (PEC) applications due to their unique properties. Nitrogen-doped graphene (NG) and metal–organic frameworks (MOFs), such as MIL-100(Fe) (where MIL stands for Materials of Lavoisier I...

  • Article
  • Open Access
15 Citations
4,707 Views
20 Pages

28 April 2020

The Gordon-Ng models are tools that have been used to estimate and evaluate the performance of various types of chillers for several years. A 550 TR centrifugal chiller plant facility was available to collect data from July and September 2018. The au...

  • Article
  • Open Access
813 Views
19 Pages

Immersive content streaming services are becoming increasingly popular on video on demand (VoD) platforms due to the growing interest in extended reality (XR) and spatial experiences. Unlike traditional VoD, immersive VoD (IVoD) offers more engaging...

  • Article
  • Open Access
18 Citations
4,226 Views
9 Pages

Comparison of the NG-Test Carba 5, Colloidal Gold Immunoassay (CGI) Test, and Xpert Carba-R for the Rapid Detection of Carbapenemases in Carbapenemase-Producing Organisms

  • Danxia Gu,
  • Zelin Yan,
  • Chang Cai,
  • Jiaping Li,
  • Yanyan Zhang,
  • Yuchen Wu,
  • Jiaxing Yang,
  • Yonglu Huang,
  • Rong Zhang and
  • Yongning Wu

Carbapenem-resistant Enterobacterales (CRE) are increasingly recognized as an urgent public health concern. The rapid and accurate identification of carbapenemases could provide insights into antimicrobial therapy and infection control. In this study...

  • Article
  • Open Access
2 Citations
1,806 Views
17 Pages

17 August 2022

The inter-cycle sleep design previously proposed as a power-saving scheme for next-generation Ethernet passive optical networks (NG-EPONs) is able to effectively decrease the power consumption of heavy-load traffic. However, with a medium to high tra...

  • Article
  • Open Access
6 Citations
2,824 Views
13 Pages

Green and Scalable Fabrication of Sandwich-like NG/SiOx/NG Homogenous Hybrids for Superior Lithium-Ion Batteries

  • Guilong Liu,
  • Yilin Wei,
  • Tiantian Li,
  • Yingying Gu,
  • Donglei Guo,
  • Naiteng Wu,
  • Aimiao Qin and
  • Xianming Liu

11 September 2021

SiOx is considered as a promising anode for next-generation Li-ions batteries (LIBs) due to its high theoretical capacity; however, mechanical damage originated from volumetric variation during cycles, low intrinsic conductivity, and the complicated...

  • Article
  • Open Access
14 Citations
2,742 Views
16 Pages

24 November 2021

Using a fairly structurally flexible and, therefore, very suitable for this type of research, superphane molecule, we demonstrate that the inclusion of a noble gas atom (Ng = He, Ne, Ar, and Kr) inside it and, thus, the formation of the Ng@superphane...

  • Article
  • Open Access
40 Citations
8,147 Views
17 Pages

19 March 2015

Ab initio and density functional theory-based computations are performed to investigate the structure and stability of H3SiNgNSi and HSiNgNSi compounds (Ng = Xe, Rn). They are thermochemically unstable with respect to the dissociation channel produc...

  • Review
  • Open Access
19 Citations
12,379 Views
25 Pages

NG2 Glia: Novel Roles beyond Re-/Myelination

  • Roberta Parolisi and
  • Enrica Boda

4 July 2018

Neuron-glia antigen 2-expressing glial cells (NG2 glia) serve as oligodendrocyte progenitors during development and adulthood. However, recent studies have shown that these cells represent not only a transitional stage along the oligodendroglial line...

  • Article
  • Open Access
4 Citations
2,457 Views
14 Pages

Inhibition of CK2 Reduces NG2 Expression in Juvenile Angiofibroma

  • Anne S. Boewe,
  • Silke Wemmert,
  • Philipp Kulas,
  • Bernhard Schick,
  • Claudia Götz,
  • Selina Wrublewsky,
  • Mathias Montenarh,
  • Michael D. Menger,
  • Matthias W. Laschke and
  • Emmanuel Ampofo

Juvenile angiofibroma (JA) is a rare fibrovascular neoplasm predominately found within the posterior nasal cavity of adolescent males. JA expresses the proteoglycan nerve–glial antigen (NG)2, which crucially determines the migratory capacity of...

  • Review
  • Open Access
7 Citations
4,883 Views
13 Pages

Immunotherapeutic Targeting of NG2/CSPG4 in Solid Organ Cancers

  • Hongyu Zhang,
  • Zhenyu Wu,
  • Deyu Hu,
  • Min Yan,
  • Jing Sun,
  • Jiejuan Lai and
  • Lianhua Bai

26 June 2022

Neuro-glia antigen 2/chondroitin sulfate proteoglycan 4 (NG2/CSPG4, also called MCSP, HMW-MAA, MSK16, MCSPG, MEL-CSPG, or gp240) is a large cell-surface antigen and an unusual cell membrane integral glycoprotein frequently expressed on undifferentiat...

  • Article
  • Open Access
1,586 Views
18 Pages

This essay defies the literary ghettoization of Asian-authored narratives and interrogates the space delineated as mainstream American feminist literature by placing Ng’s Everything in dialogue with Kate Chopin’s The Awakening and Kingsto...

  • Review
  • Open Access
10 Citations
4,848 Views
18 Pages

27 May 2024

Next-Generation Sequencing (NGS) techniques have revolutionized veterinary medicine for cats and dogs, offering insights across various domains. In veterinary parasitology, NGS enables comprehensive profiling of parasite populations, aiding in unders...

  • Article
  • Open Access
2 Citations
4,013 Views
15 Pages

Helpful Criteria When Implementing NGS Panels in Childhood Lymphoblastic Leukemia

  • Nerea Vega-Garcia,
  • Rocío Benito,
  • Elena Esperanza-Cebollada,
  • Marta Llop,
  • Cristina Robledo,
  • Clara Vicente-Garcés,
  • Javier Alonso,
  • Eva Barragán,
  • Guerau Fernández and
  • Jesús M. Hernández-Sánchez
  • + 18 authors

26 November 2020

The development of Next-Generation Sequencing (NGS) has provided useful diagnostic, prognostic, and therapeutic strategies for individualized management of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) patients. Consequently, NGS is rapidly...

  • Article
  • Open Access
12 Citations
4,344 Views
16 Pages

A Clonal NG2-Glia Cell Response in a Mouse Model of Multiple Sclerosis

  • Sonsoles Barriola,
  • Fernando Pérez-Cerdá,
  • Carlos Matute,
  • Ana Bribián and
  • Laura López-Mascaraque

21 May 2020

NG2-glia, also known as oligodendrocyte precursor cells (OPCs), have the potential to generate new mature oligodendrocytes and thus, to contribute to tissue repair in demyelinating diseases like multiple sclerosis (MS). Once activated in response to...

  • Review
  • Open Access
37 Citations
7,227 Views
18 Pages

FFPE-Based NGS Approaches into Clinical Practice: The Limits of Glory from a Pathologist Viewpoint

  • Filippo Cappello,
  • Valentina Angerilli,
  • Giada Munari,
  • Carlotta Ceccon,
  • Marianna Sabbadin,
  • Fabio Pagni,
  • Nicola Fusco,
  • Umberto Malapelle and
  • Matteo Fassan

The introduction of next-generation sequencing (NGS) in the molecular diagnostic armamentarium is deeply changing pathology practice and laboratory frameworks. NGS allows for the comprehensive molecular characterization of neoplasms, in order to prov...

  • Article
  • Open Access
1 Citations
1,388 Views
18 Pages

Dynamic of H2NG in Distribution Systems

  • Cristian Nicolae Eparu,
  • Doru Bogdan Stoica,
  • Adrian Neacsa,
  • Renata Radulescu,
  • Dragos Chiritescu,
  • Alina Petronela Prundurel and
  • Bogdan Ionete

12 January 2024

The reduction in GHG emissions has become one of the most important objectives in Europe. One of these clean technologies in the quest for large-scale decarbonisation is the blending of hydrogen and natural gas (H2NG). The significance of this articl...

  • Article
  • Open Access
2 Citations
1,942 Views
15 Pages

A Novel Digital PCR Assay for Accurate Detection and Differentiation of Focal and Non-Focal Subtypes of Mesenchymal–Epithelial Transition (MET) Gene Amplification in Lung Cancer

  • Raymond C. M. Shek,
  • Peggy S. N. Li,
  • Shelley C. M. Leung,
  • H. T. Chu,
  • F. Hioe,
  • Victor W. L. Tang,
  • Y. H. Lui,
  • Larry R. S. Lam,
  • Joshua H. Y. Ng and
  • Raiden T. S. Wong
  • + 3 authors

26 February 2025

Background/Objectives: Mesenchymal–epithelial transition (MET) gene amplification is a critical biomarker in non-small cell lung cancer (NSCLC), significantly influencing treatment decisions and prognostic evaluations. However, current detectio...

  • Article
  • Open Access
4 Citations
4,254 Views
14 Pages

Prospects of GPU Tensor Core Correlation for the SMA and the ngEHT

  • Wei Yu,
  • John W. Romein,
  • L. Jonathan Dursi,
  • Ru-Sen Lu,
  • Adrian Pope,
  • Gareth Callanan,
  • Dominic W. Pesce,
  • Lindy Blackburn,
  • Bruce Merry and
  • Ranjani Srinivasan
  • + 2 authors

11 January 2023

Building on the base of the existing telescopes of the Event Horizon Telescope (EHT) and ALMA, the next-generation EHT (ngEHT) aspires to deploy ∼10 more stations. The ngEHT targets an angular resolution of ∼15 microarcseconds. This resolutio...

  • Article
  • Open Access
1 Citations
2,278 Views
11 Pages

Characterization of Robertsonian and Reciprocal Translocations in Cattle through NGS

  • Alessandra Iannuzzi,
  • Ramona Pistucci,
  • Angela Perucatti,
  • Michele Zannotti,
  • Leopoldo Iannuzzi and
  • Pietro Parma

26 September 2023

This study presents a novel approach that combines next-generation sequencing (NGS) and cytogenetic technologies for identifying chromosomes involved in chromosomal anomalies. This research focuses on a chromosome anomaly discovered in male Alpine Gr...

  • Brief Report
  • Open Access
4 Citations
3,361 Views
7 Pages

BRCA1/2 NGS Somatic Testing in Clinical Practice: A Short Report

  • Francesco Pepe,
  • Pasquale Pisapia,
  • Gianluca Russo,
  • Mariantonia Nacchio,
  • Pierlorenzo Pallante,
  • Elena Vigliar,
  • Carmine De Angelis,
  • Luigi Insabato,
  • Claudio Bellevicine and
  • Sabino De Placido
  • + 2 authors

28 November 2021

High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of all ovarian carcinomas. HGSOC harboring BRCA1/2 germline or somatic mutations are sensitive to the poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPi). Therefore,...

  • Article
  • Open Access
12 Citations
4,133 Views
15 Pages

Targeted NGS Yields Plentiful Ultra-Rare Variants in Inborn Errors of Immunity Patients

  • Alice Grossi,
  • Maurizio Miano,
  • Marina Lanciotti,
  • Francesca Fioredda,
  • Daniela Guardo,
  • Elena Palmisani,
  • Paola Terranova,
  • Giuseppe Santamaria,
  • Francesco Caroli and
  • Roberta Caorsi
  • + 4 authors

24 August 2021

Inborn errors of immunity (IEI) include a large group of inherited diseases sharing either poor, dysregulated, or absent and/or acquired function in one or more components of the immune system. Next-generation sequencing (NGS) has driven a rapid incr...

  • Article
  • Open Access
5 Citations
2,170 Views
21 Pages

Impact of Developmental Changes of GABAA Receptors on Interneuron-NG2 Glia Transmission in the Hippocampus

  • Linda Patt,
  • Dario Tascio,
  • Catia Domingos,
  • Aline Timmermann,
  • Ronald Jabs,
  • Christian Henneberger,
  • Christian Steinhäuser and
  • Gerald Seifert

30 August 2023

NG2 glia receive synaptic input from neurons, but the functional impact of this glial innervation is not well understood. In the developing cerebellum and somatosensory cortex the GABAergic input might regulate NG2 glia differentiation and myelinatio...

  • Review
  • Open Access
1 Citations
955 Views
13 Pages

Keep an Eye on Next Generation Sequencing (NGS) Technology: Secondary Findings and Differential Diagnosis in Inherited Retinal Dystrophies (IRDs)

  • Fabiana D’Esposito,
  • Matteo Capobianco,
  • Caterina Gagliano,
  • Alessandro Avitabile,
  • Giuseppe Gagliano,
  • Gabriella Esposito,
  • Edoardo Dammino,
  • Antonio Carotenuto and
  • Marco Zeppieri

Background: Next Generation Sequencing (NGS) Technology has represented a revolution in the molecular characterization of Inherited Retinal Dystrophies (IRDs), which are among the most genetically and phenotypically heterogeneous conditions. NGS has...

  • Article
  • Open Access
8 Citations
3,348 Views
10 Pages

Comparison between Immunocytochemistry, FISH and NGS for ALK and ROS1 Rearrangement Detection in Cytological Samples

  • Diane Frankel,
  • Isabelle Nanni,
  • L’Houcine Ouafik,
  • Clara Camilla,
  • Eric Pellegrino,
  • Nathalie Beaufils,
  • Laurent Greillier,
  • Hervé Dutau,
  • Philippe Astoul and
  • Elise Kaspi
  • + 1 author

12 September 2022

The detection of ROS1 and ALK rearrangements is performed for advanced-stage non-small cell lung cancer. Several techniques can be used on cytological samples, such as immunocytochemistry (ICC), fluorescence in situ hybridization (FISH) and, more rec...

  • Article
  • Open Access
18 Citations
4,573 Views
15 Pages

Comparison of NGS and MFC Methods: Key Metrics in Multiple Myeloma MRD Assessment

  • Katharina Kriegsmann,
  • Michael Hundemer,
  • Nicole Hofmeister-Mielke,
  • Philipp Reichert,
  • Calin-Petru Manta,
  • Mohamed H.S. Awwad,
  • Sandra Sauer,
  • Uta Bertsch,
  • Britta Besemer and
  • Roland Fenk
  • + 10 authors

18 August 2020

In order to meet the challenges in data evaluation and comparability between studies in multiple myeloma (MM) minimal residual disease (MRD) assessment, the goal of the current study was to provide a step-by-step evaluation of next-generation sequenc...

  • Article
  • Open Access
18 Citations
8,623 Views
33 Pages

Framework for Adoption of Next-Generation Sequencing (NGS) Globally in the Oncology Area

  • Denis Horgan,
  • Yosr Hamdi,
  • Jonathan A. Lal,
  • Teresia Nyawira,
  • Salomé Meyer,
  • Dominique Kondji,
  • Ngiambudulu M. Francisco,
  • Roselle De Guzman,
  • Anupriya Paul and
  • Branka Bernard
  • + 15 authors

2 February 2023

Radical new possibilities of improved treatment of cancer are on offer from an advanced medical technology already demonstrating its significance: next-generation sequencing (NGS). This refined testing provides unprecedentedly precise diagnoses and p...

  • Review
  • Open Access
1 Citations
1,973 Views
43 Pages

NGS Approaches in Clinical Diagnostics: From Workflow to Disease-Specific Applications

  • Desiree Brancato,
  • Simone Treccarichi,
  • Francesca Bruno,
  • Elvira Coniglio,
  • Mirella Vinci,
  • Salvatore Saccone,
  • Francesco Calì and
  • Concetta Federico

1 October 2025

Next-Generation Sequencing (NGS) techniques have become a cornerstone of molecular diagnostics, enabling high-throughput, parallel analysis of multiple disease-associated genes. Their targeted design allows streamlined interpretation and optimised di...

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