88,586 Results Found

Benzoxazole derivative K313 has previously been reported to possess anti-inflammatory effects in lipopolysaccharide-induced RAW264.7 macrophages. To date, there have been no related reports on the anticancer effects of K313. In this study, we found t...

Various k-special functions such as k-gamma function, k-beta function and k-hypergeometric functions have been introduced and investigated. Recently, the k-gamma function of a matrix argument and k-beta function of matrix arguments have been presente...

Vitamin K and its essential role in coagulation (vitamin K [Koagulation]) have been well established and accepted the world over. Many countries have a Recommended Daily Intake (RDI) for vitamin K based on early research, and its necessary role in th...

We introduce and investigate binary (k,k)-designs, a special case of T-designs. Our combinatorial interpretation relates (k,k)-designs to the binary orthogonal arrays. We derive a general linear programming bound and propose as a consequence a univer...

Many different number systems have been the topic of research. One of the recently studied number systems is that of hybrid numbers, which are generalizations of other number systems. In this work, we introduce and study the hybrid hyper k-Pell, hybr...

Let R be a commutative ring with nonzero identity and k≥2 be a fixed integer. The k-zero-divisor hypergraph Hk(R) of R consists of the vertex set Z(R,k), the set of all k-zero-divisors of R, and the hyperedges of the form {a1,a2,a3,…,ak}, where a1,a2...

Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K can be present in various isoforms, distinguishable by two main structures, namely, phylloquinone (K1) and menaquinones (K2). The difference in structure betwe...

The contribution of non-exchangeable soil K in the total K availability may be essential to K deficient soils; however, less attention has been paid so far for proposing soil tests that assess the bioavailable structural K that is solubilized by soil...

Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin K dependent proteins. Beyond its well-known effects on blood coagulation, it also exerts relevant effects on bone and the vascular system. In this review, we...

For a given positive integer k, the k-circle formation problem asks a set of autonomous, asynchronous robots to form disjoint circles having k robots each at distinct locations, centered at a set of fixed points in the Euclidean plane. The robots are...

Inspired by prior research on fractional calculus, we introduce new fractional integral and derivative operators: the (ρ1,ρ2,k1,k2,φ)-proportional integral and the (ρ1,ρ2,k1,k2,φ)-proportional Hilfer fractional derivative. Num...

The isomorphism of Karoubi-Villamayor K-groups with smooth K-groups for monoid algebras over quasi stable locally convex algebras is established. We prove that the Quillen K-groups are isomorphic to smooth K-groups for monoid algebras over quasi-stab...

Preeclampsia (PE) is a severe pregnancy disorder with a pathophysiology not yet completely understood and without curative therapy. The histone modifications H3K4me3 and H3K9ac, as well as galectin-2 (Gal-2), are known to be decreased in PE. To gain...

In this study, firstly the definitions and basic algebraic properties of k-Oresme and k-Oresme–Lucas sequences are given. Then, various summation formulae are derived with the help of the first and second derivatives of two polynomials with k-O...

Potassium (K) is an essential macronutrient for maintaining crop productivity, but the economic benefit of K fertilizer often has been neglected. We collected a database from 60 maize field experimental sites in Northeast China between 2005 and 2012...

The paper firstly establishes the so-called n-times iterated connected sum of a simple closed k-surface in Z 3 , denoted by C k n , k ∈ { 6 , 18 , 26 } . Secondly, for a simple closed 18-surface M S S 18 , we prov...

Background/Objectives: We investigated the impact of ossification of the posterior longitudinal ligament (OPLL) and cervical alignment on K-line assessment, proposed the K-line edge category for transitioning from K-line (+) to (−), and demonst...

k-nearest neighbors (k-NN), which is known to be a simple and efficient approach, is a non-parametric supervised classifier. It aims to determine the class label of an unknown sample by its k-nearest neighbors that are stored in a training set. The k...

Among many clustering algorithms, the K-means clustering algorithm is widely used because of its simple algorithm and fast convergence. However, the K-value of clustering needs to be given in advance and the choice of K-value directly affect the conv...

Vitamin K is essential for blood coagulation and plays an important role in extrahepatic metabolism, such as in bone and blood vessels, and in energy metabolism. This review discusses the assessment of vitamin K sufficiency and the role of vitamin K...

Given a connected graph G=(V(G),E(G)), a set S⊆V(G) is said to be a k-metric generator for G if any pair of different vertices in V(G) is distinguished by at least k elements of S. A metric generator of minimum cardinality among all k-metric generato...

Whole genome sequences of two Acinetobacter baumannii clinical isolates, 48-1789 and MAR24, revealed that they carry the KL106 and KL112 capsular polysaccharide (CPS) biosynthesis gene clusters, respectively, at the chromosomal K locus. The KL106 and...

Our present investigation is mainly based on the k-hypergeometric functions which are constructed by making use of the Pochhammer k-symbol in Diaz et al. 2007, which are one of the vital generalizations of hypergeometric functions. In this study, we...

Let D=(V(D),A(D)) be a finite, simple digraph and k a positive integer. A function f:V(D)→{0,1,2,…,k+1} is called a [k]-Roman dominating function (for short, [k]-RDF) if f(AN−[v])≥|AN−(v)|+k for any vertex v∈V(D), wher...

In this paper we carry out a reliability study of the consecutive-k1 and k2-out-of-n systems with independent and identically distributed components ordered in a line. More precisely, we obtain the generating function of the structure’s reliabi...

In this paper, we define the notion of almost repdigit as a positive integer whose digits are all equal except for at most one digit, and we search all terms of the k-generalized Fibonacci sequence which are almost repdigits. In particular, we find a...

Members of the PIP4K/PIP5K family of proteins, which generate the highly important secondary messenger phosphatidylinositol-4,5-bisphosphate, play central roles in regulating diverse signaling pathways. In eukaryotic organisms, multiple isozymes and...

In this paper, we expound on the hypergeometric series solutions for the second-order non-homogeneous k-hypergeometric differential equation with the polynomial term. The general solutions of this equation are obtained in the form of k-hypergeometric...

The mechanistic target of rapamycin (mTOR) is a master regulator of protein translation, metabolism, cell growth and proliferation. It forms two complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 is frequently deregulated in many cancers, incl...

This article reviews the literature concerning the largely forgotten tobamovirus gene products for which no functions have been ascribed. One of these gene products is the 54 kDa protein, representing the RNA-dependent RNA polymerase segment of the 1...

The K+ transporter KT/HAK/KUP (K+ transporter/high-affinity K+/K+ uptake) family has a critical effect on K+ uptake and translocation in plants under different environmental conditions. However, the functional analysis of KT/HAK/KUP members in sweet...

Adenovirus makes extensive use of alternative RNA splicing to produce a complex set of spliced viral mRNAs. Studies aimed at characterizing the interactions between the virus and the host cell RNA splicing machinery have identified three viral protei...

Let k ≥ 1 be an integer and denote ( F k , n ) n as the k-Fibonacci sequence whose terms satisfy the recurrence relation F k , n = k F k , n − 1 + F k , n − 2 , with initial conditions F k...

Recently, the notion of a classical k-metric, which make the triangle inequality to a more general axiom: d(x,z)≤k(d(x,y)+d(y,z)), has been presented and is applied in many fields. In this paper, the definitions of an (L,M)-fuzzy k-pseudo metric a...

Two new initialization methods for K-means clustering are proposed. Both proposals are based on applying a divide-and-conquer approach for the K-means‖ type of an initialization strategy. The second proposal also uses multiple lower-dimensional subsp...

Chemotherapy remains the most common cancer treatment. Although chemotherapeutic drugs induce tumor cell senescence, they are often associated with post-therapy tumor recurrence by inducing the senescence-associated secretory phenotype (SASP). Theref...

In this paper, with the help of the Hardy and Dedekind sums we will give many properties of the sum B 1 ( h , k ) , which was defined by Cetin et al. Then we will give the connections of this sum with the other well-known finite sums such...

Let k be a positive integer, and set [ k ] : = { 1 , 2 , … , k } . For a graph G, a k-rainbow dominating function (or kRDF) of G is a mapping f : V ( G ) → 2 [ k ] in such a way that, for any vertex v &isin...

Vitamin K is a group of lipophilic molecules. Forms of vitamin K play an essential role in the activation of specific proteins involved in blood clotting cascade or bone metabolism. Another molecule belonging to the fat-soluble vitamins group that al...

Given an integer k ≥ 2, a k-path is a path on k vertices. A set of vertices in a graph G is called a k-path vertex cover if it includes at least one vertex of every k-path of G. A minimum k-path vertex cover in G is a k-path vertex cover having th...

We introduce and discuss the concept of n-ary K-increasing fusion functions and n-ary K-increasing aggregation functions, K being a subset of the index set {1,…,n} indicating in which variables a considered function is increasing. It is also a...

The monotonicity of multi-valued operators serves as a guideline to prove the existence of the results in this article. This theory focuses on the existence of solutions without continuity and compactness conditions. We study these results for the (k...

Nowadays there is a large amount of information at our disposal, which is increasing day by day, and right now the question is not whether we have a method to process it, but which method is most effective, faster and best. When processing large data...

In this study, we present our improved RANS results of the missile aerodynamic flow computation involving leading edge vortex separation. We have used our in-house tailored version of the open source finite volume solver FlowPsi. An ongoing study in...

In this paper, the concept of a k-(quasi) pseudo metric is generalized to the L-fuzzy case, called a pointwise k-(quasi) pseudo metric, which is considered to be a map d:J(LX)×J(LX)⟶[0,∞) satisfying some conditions. What is more, it is proved that th...

Neutrosophic sets and soft sets are two different mathematical tools for representing vagueness and uncertainty. We apply these models in combination to study vagueness and uncertainty in K-algebras. We introduce the notion of single-valued neutrosop...

Lymphocytes express potassium channels that regulate physiological cell functions, such as activation, proliferation and migration. Expression levels of K2P5.1 (TASK2; KCNK5) channels belonging to the family of two-pore domain potassium channels have...

This study investigated whether alterations in the expression of genes integral to the c-Jun N-terminal kinase (JNK) signaling pathway play a role in the pathogenesis of colorectal cancer (CRC). It analyzed the expression of genes encoding two JNK is...

Exposure to moderately high temperature enables plants to acquire thermotolerance to high temperatures that might otherwise be lethal. In Arabidopsis thaliana, histone H3 lysine 27 trimethylation (H3K27me3) at the heat shock protein 17.6C (HSP17.6C)...

Stimulus-dependent elevation of intracellular Ca2+ affects gene expression via well-documented calmodulin-mediated signaling pathways. Recently, we found that the addition of extra- and intracellular Ca2+ chelators increased, rather than decreased, t...