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Most Cited

  • Review
  • Open Access
621 Citations
64,420 Views
54 Pages

15 November 2023

Antibiotics have revolutionized medicine, saving countless lives since their discovery in the early 20th century. However, the origin of antibiotics is now overshadowed by the alarming rise in antibiotic resistance. This global crisis stems from the...

  • Review
  • Open Access
365 Citations
67,801 Views
31 Pages

18 July 2023

Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively st...

  • Review
  • Open Access
357 Citations
70,679 Views
11 Pages

The Role of AI in Drug Discovery: Challenges, Opportunities, and Strategies

  • Alexandre Blanco-González,
  • Alfonso Cabezón,
  • Alejandro Seco-González,
  • Daniel Conde-Torres,
  • Paula Antelo-Riveiro,
  • Ángel Piñeiro and
  • Rebeca Garcia-Fandino

Artificial intelligence (AI) has the potential to revolutionize the drug discovery process, offering improved efficiency, accuracy, and speed. However, the successful application of AI is dependent on the availability of high-quality data, the addres...

  • Review
  • Open Access
218 Citations
17,831 Views
68 Pages

Nitrogen Containing Heterocycles as Anticancer Agents: A Medicinal Chemistry Perspective

  • Adarsh Kumar,
  • Ankit Kumar Singh,
  • Harshwardhan Singh,
  • Veena Vijayan,
  • Deepak Kumar,
  • Jashwanth Naik,
  • Suresh Thareja,
  • Jagat Pal Yadav,
  • Prateek Pathak and
  • Maria Grishina
  • + 5 authors

14 February 2023

Cancer is one of the major healthcare challenges across the globe. Several anticancer drugs are available on the market but they either lack specificity or have poor safety, severe side effects, and suffer from resistance. So, there is a dire need to...

  • Review
  • Open Access
175 Citations
26,292 Views
22 Pages

22 December 2023

In the dynamic landscape of drug discovery, Computer-Aided Drug Design (CADD) emerges as a transformative force, bridging the realms of biology and technology. This paper overviews CADDs historical evolution, categorization into structure-based and l...

  • Review
  • Open Access
152 Citations
22,262 Views
42 Pages

Current Overview of Metal Nanoparticles’ Synthesis, Characterization, and Biomedical Applications, with a Focus on Silver and Gold Nanoparticles

  • Ana Flavia Burlec,
  • Andreia Corciova,
  • Monica Boev,
  • Denisa Batir-Marin,
  • Cornelia Mircea,
  • Oana Cioanca,
  • Gabriela Danila,
  • Marius Danila,
  • Anca Florentina Bucur and
  • Monica Hancianu

4 October 2023

Metal nanoparticles (NPs) have garnered considerable attention, due to their unique physicochemical properties, that render them promising candidates for various applications in medicine and industry. This article offers a comprehensive overview of t...

  • Review
  • Open Access
151 Citations
21,028 Views
20 Pages

17 March 2023

In recent years, biodegradable polymers have gained the attention of many researchers for their promising applications, especially in drug delivery, due to their good biocompatibility and designable degradation time. Poly (lactic-co-glycolic acid) (P...

  • Review
  • Open Access
143 Citations
35,013 Views
21 Pages

A Review of Pickering Emulsions: Perspectives and Applications

  • Fernanda Brito de Carvalho-Guimarães,
  • Kamila Leal Correa,
  • Tatiane Pereira de Souza,
  • Jesus Rafael Rodríguez Amado,
  • Roseane Maria Ribeiro-Costa and
  • José Otávio Carréra Silva-Júnior

15 November 2022

Pickering emulsions are systems composed of two immiscible fluids stabilized by organic or inorganic solid particles. These solid particles of certain dimensions (micro- or nano-particles), and desired wettability, have been shown to be an alternativ...

  • Review
  • Open Access
131 Citations
30,659 Views
34 Pages

Exploring the Benefits of Phycocyanin: From Spirulina Cultivation to Its Widespread Applications

  • Raquel Fernandes,
  • Joana Campos,
  • Mónica Serra,
  • Javier Fidalgo,
  • Hugo Almeida,
  • Ana Casas,
  • Duarte Toubarro and
  • Ana I. R. N. A. Barros

14 April 2023

Large-scale production of microalgae and their bioactive compounds has steadily increased in response to global demand for natural compounds. Spirulina, in particular, has been used due to its high nutritional value, especially its high protein conte...

  • Review
  • Open Access
122 Citations
12,539 Views
23 Pages

Potential of Copper and Copper Compounds for Anticancer Applications

  • Peng Ji,
  • Peng Wang,
  • Hao Chen,
  • Yajing Xu,
  • Jianwen Ge,
  • Zechong Tian and
  • Zhirong Yan

3 February 2023

Inducing cancer cell death has always been a research hotspot in life sciences. With the continuous deepening and diversification of related research, the potential value of metal elements in inducing cell death has been explored. Taking iron as an e...

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Pharmaceuticals - ISSN 1424-8247