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Molecules, Volume 19, Issue 11

November 2014 - 128 articles

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Articles (128)

  • Article
  • Open Access
70 Citations
10,338 Views
10 Pages

Antifungal Compounds Produced by Colletotrichum gloeosporioides, an Endophytic Fungus from Michelia champaca

  • Vanessa Mara Chapla,
  • Maria Luiza Zeraik,
  • Ioanis Hcristos Leptokarydis,
  • Geraldo Humberto Silva,
  • Vanderlan Silva Bolzani,
  • Maria Claudia M. Young,
  • Ludwig Heinrich Pfenning and
  • Angela Regina Araújo

21 November 2014

In this study, eight endophytic fungi were isolated from the leaves, stems and roots of Michelia champaca. The isolates were screened and evaluated for their antifungal, anticancer and acetylcholinesterase (AChE) inhibitory activities. All of the ext...

  • Article
  • Open Access
67 Citations
10,742 Views
23 Pages

Volatile Profiling of Aromatic Traditional Medicinal Plant, Polygonum minus in Different Tissues and Its Biological Activities

  • Rafidah Ahmad,
  • Syarul Nataqain Baharum,
  • Hamidun Bunawan,
  • Minki Lee,
  • Normah Mohd Noor,
  • Emelda Roseleena Rohani,
  • Norashikin Ilias and
  • Noraziah Mohamad Zin

20 November 2014

The aim of this research was to identify the volatile metabolites produced in different organs (leaves, stem and roots) of Polygonum minus, an important essential oil producing crop in Malaysia. Two methods of extraction have been applied: Solid Phas...

  • Article
  • Open Access
35 Citations
8,325 Views
16 Pages

Synthesis and Biological Evaluation of New Pleuromutilin Derivatives as Antibacterial Agents

  • Ruo-Feng Shang,
  • Guan-Hua Wang,
  • Xi-Ming Xu,
  • Si-Jie Liu,
  • Chao Zhang,
  • Yun-Peng Yi,
  • Jian-Ping Liang and
  • Yu Liu

19 November 2014

Several pleuromutilin derivatives possessing thiadiazole moieties were synthesized via acylation reactions under mild conditions. The in vitro antibacterial activities of the derivatives against methicillin-resistant S. aureus, methicillin-resistant...

  • Article
  • Open Access
84 Citations
43,666 Views
12 Pages

Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts

  • Chung-Hsun Chang,
  • Wen-Chung Tsai,
  • Ya-Hui Hsu and
  • Jong-Hwei Su Pang

19 November 2014

BPC 157, a pentadecapeptide derived from human gastric juice, has been demonstrated to promote the healing of different tissues, including skin, muscle, bone, ligament and tendon in many animal studies. However, the underlying mechanism has not been...

  • Article
  • Open Access
27 Citations
9,291 Views
19 Pages

Composition and Antioxidant Activity of the Anthocyanins of the Fruit of Berberis heteropoda Schrenk

  • Li-Li Sun,
  • Wan Gao,
  • Meng-Meng Zhang,
  • Cheng Li,
  • Ai-Guo Wang,
  • Ya-Lun Su and
  • Teng-Fei Ji

19 November 2014

In present study, the anthocyanin composition and content of the fruit of B. heteropoda Schrenk were determined for the first time. The total anthocyanins were extracted from the fruit of B. heteropoda Schrenk using 0.5% HCl in 80% methanol and were...

  • Article
  • Open Access
63 Citations
7,992 Views
17 Pages

Aroma-Active Compounds in Jinhua Ham Produced With Different Fermentation Periods

  • Xiao-Sheng Liu,
  • Jian-Bin Liu,
  • Zheng-Mao Yang,
  • Huan-Lu Song,
  • Ye Liu and
  • Ting-Ting Zou

19 November 2014

The aroma-active compounds in Jinhua ham processed and stored for 9, 12, 15 and 18 months were extracted by dynamic headspace sampling (DHS) and solvent-assisted flavor evaporation (SAFE) and analyzed by gas chromatography-olfactometry-mass spectrome...

  • Article
  • Open Access
23 Citations
8,956 Views
23 Pages

Vernonia kotschyana Roots: Therapeutic Potential via Antioxidant Activity

  • Alexandru Vasincu,
  • Berit S. Paulsen,
  • Drissa Diallo,
  • Ioana Vasincu,
  • Ana C. Aprotosoaie,
  • Veronica Bild,
  • Christiana Charalambous,
  • Andreas I. Constantinou,
  • Anca Miron and
  • Cristina M. Gavrilescu

19 November 2014

The roots of Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae) are used in Malian traditional medicine in the treatment of gastroduodenal ulcers and gastritis. Since oxidative stress is involved in gastric ulceration, the aim of this study was to s...

  • Review
  • Open Access
42 Citations
15,591 Views
15 Pages

Synthetic Applications of Intramolecular Thiol-Ene “Click” Reactions

  • Eoin M. Scanlan,
  • Vincent Corcé and
  • Aoife Malone

19 November 2014

The intermolecular thiol-ene reaction is emerging as a highly efficient; free-radical mediated “click” process with diverse applications in biofunctionalisation and materials science. The related intramolecular thiol-ene reactions offer significant p...

  • Article
  • Open Access
7 Citations
9,105 Views
20 Pages

Spectral and Kinetic Properties of Radicals Derived from Oxidation of Quinoxalin-2-One and Its Methyl Derivative

  • Konrad Skotnicki,
  • Julio R. De la Fuente,
  • Alvaro Cañete and
  • Krzysztof Bobrowski

19 November 2014

The kinetics and spectral characteristics of the transients formed in the reactions of •OH and •N3 with quinoxalin-2(1H)-one (Q), its methyl derivative, 3-methylquinoxalin-2(1H)-one (3-MeQ) and pyrazin-2-one (Pyr) were studied by pulse radiolysis in...

  • Article
  • Open Access
18 Citations
9,409 Views
8 Pages

Anti-Cholinesterase Activity of Lycopodium Alkaloids from Vietnamese Huperzia squarrosa (Forst.) Trevis

  • Nguyen Ngoc Chuong,
  • Nguyen Thi Thu Huong,
  • Tran Manh Hung and
  • Tran Cong Luan

19 November 2014

A series of Lycopodium alkaloids, namely lycosquarosine A (1), acetylaposerratinine (2), huperzine A (3), huperzine B (4), 8α-hydrophlemariurine B (5), and huperzinine (6), has been isolated from Vietnamese Huperzia squarrosa. Among them, lycosquaros...

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Molecules - ISSN 1420-3049