Molecules 2014, 19(11), 17478-17535; https://doi.org/10.3390/molecules191117478
A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.
Qing Xia 1,†, Huazheng Zhang 2,†, Xuefei Sun 1, Haijuan Zhao 1, Lingfang Wu 1, Dan Zhu 1, Guanghui Yang 1, Yanyan Shao 1, Xiaoxue Zhang 1, Xin Mao 1, Lanzhen Zhang 1,*
and Gaimei She 1,*
and Gaimei She 1,*
1
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China
2
School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China
â€
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 11 July 2014 / Revised: 13 August 2014 / Accepted: 15 August 2014 / Published: 30 October 2014
(This article belongs to the Section Metabolites)
Abstract
Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and 13C-NMR spectral data. View Full-TextKeywords:
Ganoderma; triterpenes; chemical structure; 13C-NMR data; bioactivity
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Xia, Q.; Zhang, H.; Sun, X.; Zhao, H.; Wu, L.; Zhu, D.; Yang, G.; Shao, Y.; Zhang, X.; Mao, X.; Zhang, L.; She, G. A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.. Molecules 2014, 19, 17478-17535.
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