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Molecules, Volume 19, Issue 10

October 2014 - 100 articles

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Articles (100)

  • Article
  • Open Access
21 Citations
8,342 Views
11 Pages

Accumulation of Kaempferitrin and Expression of Phenyl-Propanoid Biosynthetic Genes in Kenaf (Hibiscus cannabinus)

  • Shicheng Zhao,
  • Xiaohua Li,
  • Dong Ha Cho,
  • Mariadhas Valan Arasu,
  • Naif Abdullah Al-Dhabi and
  • Sang Un Park

23 October 2014

Kenaf (Hibiscus cannabinus) is cultivated worldwide for its fiber; however, the medicinal properties of this plant are currently attracting increasing attention. In this study, we investigated the expression levels of genes involved in the biosynthes...

  • Review
  • Open Access
62 Citations
13,305 Views
28 Pages

New Developments in Spin Labels for Pulsed Dipolar EPR

  • Alistair J. Fielding,
  • Maria Grazia Concilio,
  • Graham Heaven and
  • Michael A. Hollas

23 October 2014

Spin labelling is a chemical technique that enables the integration of a molecule containing an unpaired electron into another framework for study. Given the need to understand the structure, dynamics, and conformational changes of biomacromolecules,...

  • Article
  • Open Access
24 Citations
9,055 Views
26 Pages

Structural Diversity of Copper(II) Complexes with N-(2-Pyridyl)Imidazolidin-2-Ones(Thiones) and Their in Vitro Antitumor Activity

  • Łukasz Balewski,
  • Franciszek Sączewski,
  • Patrick J. Bednarski,
  • Maria Gdaniec,
  • Ewa Borys and
  • Anna Makowska

23 October 2014

Six series of structurally different mono- and binuclear copper(II) complexes 5–10 were obtained by reacting N-(2-pyridyl)imidazolidin-2-ones (1a–l), N,N'-bis(2-pyridyl)imidazolidin-2-ones (2a,b), N-acyl-N'(2-pyridyl)imidazolodin-2-ones (3a–j) and...

  • Article
  • Open Access
21 Citations
10,007 Views
14 Pages

23 October 2014

Deuterated polyethylene targets have been irradiated by means of a 1016 W/cm2 laser using 600 J pulse energy, 1315 nm wavelength, 300 ps pulse duration and 70 micron spot diameter. The plasma parameters were measured using on-line diagnostics based o...

  • Article
  • Open Access
47 Citations
7,860 Views
12 Pages

22 October 2014

As one of the most important components of Panax ginseng, ginsenoside Rg1 has certain anti-aging effects, improving the activity of learning and memory. Studies have showed that ginsenoside Rg1 improves the memory impairment associated with Alzheimer...

  • Article
  • Open Access
38 Citations
10,161 Views
13 Pages

Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

  • Kristoff T. Homan,
  • Emily Wu,
  • Alessandro Cannavo,
  • Walter J. Koch and
  • John J. G. Tesmer

22 October 2014

G protein-coupled receptor kinases (GRKs) have been implicated in human diseases ranging from heart failure to diabetes. Previous studies have identified several compounds that selectively inhibit GRK2, such as paroxetine and balanol. Far fewer selec...

  • Letter
  • Open Access
19 Citations
8,018 Views
9 Pages

Efficient Synthesis of Kinsenoside and Goodyeroside A by a Chemo-Enzymatic Approach

  • Yang Zhang,
  • Yihong Xia,
  • Yongji Lai,
  • Fang Tang,
  • Zengwei Luo,
  • Yongbo Xue,
  • Guangmin Yao,
  • Yonghui Zhang and
  • Jinwen Zhang

22 October 2014

Kinsenoside (1) and goodyeroside A (2), two naturally occurring stereoisomers with diverse biological activities, have been synthesized efficiently by a chemo-enzymatic approach with a total yield of 12.7%. The aglycones, (R)- and (S)-3-hydroxy-γ-but...

  • Article
  • Open Access
62 Citations
8,835 Views
17 Pages

Antioxidant, 5-Lipoxygenase Inhibitory and Cytotoxic Activities of Compounds Isolated from the Ferula lutea Flowers

  • Mansour Znati,
  • Hichem Ben Jannet,
  • Sylvie Cazaux,
  • Jean Pierre Souchard,
  • Féthia Harzallah Skhiri and
  • Jalloul Bouajila

22 October 2014

A phytochemical investigation of the Ferula lutea (Poir.) Maire flowers has led to the isolation of a new compound, (E)-5-ethylidenefuran-2(5H)-one-5-O-β-D-glucopyranoside (1), designated ferunide, 4-hydroxy-3-methylbut-2-enoic acid (2), reported for...

  • Article
  • Open Access
9 Citations
6,366 Views
11 Pages

22 October 2014

Formation of mixed-ligand Pd2+ complexes between canonical nucleoside 5'-monophosphates and five metal-ion-binding nucleoside analogs has been studied by 1H-NMR spectroscopy to test the ability of these nucleoside surrogates to discriminate between...

  • Article
  • Open Access
5 Citations
7,847 Views
10 Pages

The Use of Headspace Solid-Phase Microextraction (HS-SPME) to Assess the Quality and Stability of Fruit Products: An Example Using Red Mombin Pulp (Spondias purpurea L.)

  • Katieli Martins Todisco,
  • Victor Costa Castro-Alves,
  • Deborah Dos Santos Garruti,
  • José Maria Correia da Costa and
  • Edmar Clemente

21 October 2014

The present study aimed to evaluate the volatiles profile of red mombin (Spondias purpurea) pulp and its powder produced by spray-drying (SD) as an example to show utility of headspace solid-phase microextraction (HS-SPME) in the analysis of paramete...

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Molecules - ISSN 1420-3049Creative Common CC BY license