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475 Results Found

  • Review
  • Open Access

Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors

  • Carol Yen,
  • John W. Epling,
  • Michelle Rockwell and
  • Monifa Vaughn-Cooke

Diagnostic errors have been a critical concern in healthcare, leading to substantial financial burdens and serious threats to patient safety. The Improving Diagnosis in Health Care report by the National Academies of Sciences, Engineering, and Medici...

  • Perspective
  • Open Access
1,134 Views
16 Pages

Prehabilitation: A Catalyst for Transforming Toward Value-Based, Personalized Perioperative Health and Care

  • Brenda H. van Koningsveld-Couperus,
  • Thijs de Rooij,
  • Nico L. van Meeteren,
  • Benedikt Preckel,
  • Markus W. Hollmann and
  • Gertrude J. Nieuwenhuijs-Moeke

24 September 2025

The growing strain on global healthcare systems, driven by aging populations, rising prevalence of chronic diseases, and workforce shortages, has increased interest in strategies that enhance perioperative outcomes and healthcare sustainability. From...

  • Article
  • Open Access
5 Citations
4,114 Views
14 Pages

Reduction in Temperature-Dependent Fiber-Optic Gyroscope Bias Drift by Using Multifunctional Integrated Optical Chip Fabricated on Pre-Annealed LiNbO3

  • Ercan Karagöz,
  • Fatma Yasemin Aşık,
  • Mutlu Gökkavas,
  • Erkut Emin Akbaş,
  • Aylin Yertutanol,
  • Ekmel Özbay and
  • Şadan Özcan

11 November 2024

The refractive index change obtained after annealed proton exchange (APE) in lithium niobate (LiNbO3) crystals depends on both the proton exchange process carried out in hot acid and the structure of the crystals. In devices produced by the APE metho...

  • Protocol
  • Open Access
222 Views
15 Pages

One Health Approach to Nutritional Status and Well-Being in Food Supply Chain Workers: A Study Protocol

  • Mariacristina Siotto,
  • Carola Cocco,
  • Chiara Bertoncini,
  • Alessandro Guerrini,
  • Valeria Habib,
  • Erika Antonacci,
  • Elisabetta Ruco and
  • Irene Giovanna Aprile

The agri-food supply chain is a relevant contributor to the Italian economy but shows a high incidence of occupational injuries and musculoskeletal disorders, such as lower back pain. Repetitive manual handling and biomechanical overload highlight th...

  • Article
  • Open Access
8 Citations
3,375 Views
26 Pages

1 November 2019

The transportation sector is undergoing electrification to gain advantages such as lighter weight, improved reliability, and enhanced efficiency. As contributors to the safety of embedded critical functions in electrified systems, better sizing of el...

  • Review
  • Open Access
3,231 Views
34 Pages

Review of Challenges in Heat Exchanger Network Development for Electrified Industrial Energy Systems

  • Stanislav Boldyryev,
  • Oleksandr S. Ivashchuk,
  • Goran Krajačić and
  • Volodymyr M. Atamanyuk

12 July 2025

Shifting towards electrified industrial energy systems is pivotal for meeting global decarbonization objectives, especially since process heat is a significant contributor to greenhouse gas emissions in the industrial sector. This review examines the...

  • Perspective
  • Open Access
21 Citations
4,783 Views
16 Pages

Mobile-Energy-as-a-Service (MEaaS): Sustainable Electromobility via Integrated Energy–Transport–Urban Infrastructure

  • Mahinda Vilathgamuwa,
  • Yateendra Mishra,
  • Tan Yigitcanlar,
  • Ashish Bhaskar and
  • Clevo Wilson

27 February 2022

The transport sector is one of the leading contributors of anthropogenic climate change. Particularly, internal combustion engine (ICE) dominancy coupled with heavy private motor vehicle dependency are among the main issues that need to be addressed...

  • Article
  • Open Access
1 Citations
3,173 Views
16 Pages

Set When the Sun Rises, Rise When the Sun Sets: Climate Impact on Health, Safety, and Wellbeing of Smallholder Farmers in Vietnam

  • Miranda Dally,
  • Thuy Thi Thu Tran,
  • Thanh Le Nhat Nguyen,
  • Quynh Nguyen,
  • Lee S. Newman,
  • Mike Van Dyke,
  • Marcela Tamayo-Ortiz,
  • James Crooks,
  • Lyndsay Krisher and
  • Megan Cherewick

7 September 2024

Vietnam is a country most at risk for experiencing climate change effects, especially increasing temperatures. Agricultural production is one of the biggest contributors to Vietnam’s economy. Recent research has explored how climate change will...

  • Review
  • Open Access
5 Citations
5,412 Views
20 Pages

Application of Digital Twin Technology in Smart Agriculture: A Bibliometric Review

  • Rajesh Gund,
  • Chetan M. Badgujar,
  • Sathishkumar Samiappan and
  • Sindhu Jagadamma

22 August 2025

Digital twin technology is reshaping modern agriculture. Digital twins are the virtual replicas of real-world farming systems, which are continuously updated with real-time data, and are revolutionizing the monitoring, simulation, and optimization of...

  • Article
  • Open Access
157 Views
18 Pages

16 January 2026

Background: Post-exercise recovery involves coordinated metabolic restoration and redox rebalancing. Although dietary polyphenols have been proposed to facilitate recovery, the metabolic mechanisms underlying their effects—particularly during t...

  • Article
  • Open Access
24 Citations
10,493 Views
19 Pages

Using Crowdsourced Trajectories for Automated OSM Data Entry Approach

  • Anahid Basiri,
  • Pouria Amirian and
  • Peter Mooney

15 September 2016

The concept of crowdsourcing is nowadays extensively used to refer to the collection of data and the generation of information by large groups of users/contributors. OpenStreetMap (OSM) is a very successful example of a crowd-sourced geospatial data...

  • Article
  • Open Access
3 Citations
2,567 Views
15 Pages

Health Risk Assessment of Ambient Volatile Organic Compounds in a Border City in Canada

  • Taraneh Mihankhah,
  • Yushan Su,
  • Tianchu Zhang,
  • Jonathan Wang,
  • James Gilmore,
  • Michael Noble,
  • Anthony Munoz,
  • Chris Charron and
  • Xiaohong Xu

28 August 2024

This study characterizes cancer and non-cancer risks due to inhalation exposure to volatile organic compounds (VOCs) in a border city of Windsor in southern Ontario, Canada, using hourly ambient concentrations collected from 17 November 2021 to 17 Ma...

  • Article
  • Open Access
16 Citations
4,749 Views
17 Pages

15 October 2019

Global warming is now considered to be one of the greatest challenges worldwide. International environmental agreements have been developed in response to climate change since the 1970s. The construction industry is considered one of the main contrib...

  • Proceeding Paper
  • Open Access
4 Citations
1,738 Views
3 Pages

Oxidative Stress Applied in Diabetes Mellitus-A New Paradigm

  • Anca Pantea Stoian,
  • Grigorina Mitrofan,
  • Florian Colceag,
  • Cristian Serafinceanu,
  • Eugenia Eftimie Totu,
  • Veronica Mocanu,
  • Daniela Mănuc and
  • Elena Mihaela Cărăuşu

Although obesity and a sedentary lifestyle are well-known risk factors for type 2 diabetes, at molecular level, the oxidative stress is regarded as the primary contributor to the pathogenic process. Our work intends to evidence how the thinking model...

  • Article
  • Open Access
9 Citations
3,090 Views
16 Pages

Quality of GNSS Traces from VGI: A Data Cleaning Method Based on Activity Type and User Experience

  • Aitor Àvila Callau,
  • Yolanda Pérez-Albert and
  • David Serrano Giné

VGI (Volunteered Geographic Information) refers to spatial data collected, created, and shared voluntarily by users. Georeferenced tracks are one of the most common components of VGI, and, as such, are not free from errors. The cleaning of GNSS (Glob...

  • Article
  • Open Access
8 Citations
2,067 Views
18 Pages

Evaluation of PM Chemical Composition in Thessaloniki, Greece Based on Air Quality Simulations

  • Dimitrios Theodoros Tsiaousidis,
  • Natalia Liora,
  • Serafim Kontos,
  • Anastasia Poupkou,
  • Dimitris Akritidis and
  • Dimitrios Melas

25 June 2023

The average PM10 daily levels over the urban area of Thessaloniki, Greece, usually exceed the air quality limits and therefore the improved PM chemical composition and air quality modeling results that will facilitate the design of the most appropria...

  • Article
  • Open Access
3 Citations
1,862 Views
25 Pages

Success Evaluation Index Model for Running Healthcare Projects in Hong Kong: A Delphi Approach

  • Goodenough D. Oppong,
  • Albert Ping-Chuen Chan,
  • Man-Wai Chan,
  • Amos Darko and
  • Michael A. Adabre

22 January 2025

Hospital projects or healthcare projects (HPs) are major contributors of greenhouse gas emissions, high energy consumption, and environmental pollution. These problems serve as a clarion call for the development of a standardized list of metrics that...

  • Article
  • Open Access
2 Citations
2,021 Views
16 Pages

28 February 2025

Remotely piloted aircraft are a fast-emerging sector of the aviation industry. Although technical failures have been the largest cause of accident occurrences for Remotely Piloted Aircraft Systems (RPASs), if they are to follow the path of convention...

  • Article
  • Open Access
25 Citations
3,794 Views
15 Pages

Heavy metal pollution has become a great concern due to its adverse effects on the ecological system and human health. The present study investigated the concentrations of six common heavy metals (Cr, Cu, Zn, As, Cd, and Pb) in the Tianjin coastal ar...

  • Article
  • Open Access
4 Citations
3,471 Views
15 Pages

6 November 2019

We utilized a high dimensional financial network to investigate the systemic risk contagion between different industries in China and to explore the impacts of monetary policy and industry heterogeneity factors. The empirical results suggest that the...

  • Article
  • Open Access
2 Citations
1,854 Views
23 Pages

11 May 2024

Groundwater-influenced ecosystems (GIEs) are increasingly vulnerable due to groundwater extraction, land-use practices, and climate change. These ecosystems receive groundwater inflow as a portion of their baseflow or water budget, which can maintain...

  • Review
  • Open Access
83 Citations
13,678 Views
19 Pages

8 November 2019

The pathogenesis of an increasing number of chronic diseases is being attributed to effects of the immune system. However, its role in the development and maintenance of anorexia nervosa is seemingly under-appreciated. Yet, in examining the available...

  • Review
  • Open Access
2,740 Views
19 Pages

Oral health is crucial to overall health, and periodontal disease (PDD) is a chronic inflammatory disease. Over the past decade, PDD has been recognized as a significant contributor to systemic inflammation. Here, we relate our seminal work defining...

  • Article
  • Open Access
4 Citations
3,732 Views
13 Pages

Plant-Based Nutritional Supplementation Attenuates LPS-Induced Low-Grade Systemic Activation

  • Jin Yu,
  • Hong Zhu,
  • Saeid Taheri,
  • William Mondy,
  • Stephen Perry and
  • Mark S. Kindy

Plant-based nutritional supplementation has been shown to attenuate and reduce mortality in the processes of both acute and chronic disorders, including diabetes, obesity, cardiovascular disease, cancer, inflammatory diseases, and neurological and ne...

  • Article
  • Open Access
1,195 Views
26 Pages

6 June 2025

Open Source Software (OSS) development is a complex socio-technical system in which collaborator attitudes influence the outcomes. This study empirically analyzes the impact of participant sentiment (positive, neutral, negative) on productivity, defi...

  • Article
  • Open Access
12 Citations
5,372 Views
20 Pages

Life Cycle Assessment of Spinach Produced in Central and Southern Italy

  • Ester Foppa Pedretti,
  • Kofi Armah Boakye-Yiadom,
  • Elena Valentini,
  • Alessio Ilari and
  • Daniele Duca

7 September 2021

Environmental sustainability continues to attract global interest, especially due to the issue of climate change. The agri-food sector is considered a major contributor to climate change as processes and activities within the sector can negatively im...

  • Article
  • Open Access
3 Citations
2,288 Views
26 Pages

A Case Study on the Convection Initiation Mechanisms over the Northern Edge of Tarim Basin, Xinjiang, Northwest China

  • Aerzuna Abulimiti,
  • Qi Sun,
  • Lin Yuan,
  • Yongqiang Liu,
  • Junqiang Yao,
  • Lianmei Yang,
  • Jie Ming and
  • Abuduwaili Abulikemu

3 October 2023

The convection initiation (CI) mechanisms of severe storms have received increasing attention because severe storms have been occurring more frequently around the globe in recent years. In this work, the CI mechanisms of severe convective weather ass...

  • Article
  • Open Access
1 Citations
5,537 Views
19 Pages

23 February 2024

In this convergent parallel mixed-methods study, we investigated the early impact of the COVID-19 stay-at-home mandate in Illinois on 16 caregivers of children with autism. Our goal was to understand contributors to caregivers’ stress by integr...

  • Article
  • Open Access
1 Citations
633 Views
15 Pages

30 September 2025

Investigating atmospheric volatile organic compounds (VOCs) is critical for understanding their sources, chemical reactivity, and impacts on air quality, climate, and human health, especially in remote regions like the Tibetan Plateau where baseline...

  • Article
  • Open Access
4 Citations
8,693 Views
16 Pages

Acceleration of Trading System Back End with FPGAs Using High-Level Synthesis Flow

  • Sunil Puranik,
  • Mahesh Barve,
  • Swapnil Rodi and
  • Rajendra Patrikar

FPGA technology is widely used in the finance domain. We describe the design of a financial trading system order processing component using FPGAs, implemented with high-level synthesis (HLS) flow. The order processing component is the major contribut...

  • Article
  • Open Access
9 Citations
3,231 Views
19 Pages

24 August 2022

Mitochondrial dysfunction and oxidative stress are major contributors to the pathophysiology of neurodegenerative diseases, including Alzheimer’s disease (AD). However, the mechanisms driving mitochondrial dysfunction and oxidative stress are u...

  • Article
  • Open Access
1 Citations
469 Views
17 Pages

Composition, Sources, and Health Risks of Polycyclic Aromatic Hydrocarbons in Commonly Consumed Fish and Crayfish from Caohai Lake, Southwest China

  • Yupei Hao,
  • Tianyao Yang,
  • Xueqin Wei,
  • Xu Zhang,
  • Xiongyi Miao,
  • Gaohai Xu,
  • Sheping Yang,
  • Xiaohua Zhou,
  • Huifang Zhao and
  • Wei Bao

17 December 2025

This study investigated the occurrence, sources, and health risks of 16 polycyclic aromatic hydrocarbons (PAHs) in commonly consumed fish and crayfish from the Caohai Lake, a typical plateau lake in southwest China. Four dominant species (crucian car...

  • Article
  • Open Access
2 Citations
3,511 Views
24 Pages

Systemic LPS Administration Stimulates the Activation of Non-Neuronal Cells in an Experimental Model of Spinal Muscular Atrophy

  • Eleni Karafoulidou,
  • Evangelia Kesidou,
  • Paschalis Theotokis,
  • Chrystalla Konstantinou,
  • Maria-Konstantina Nella,
  • Iliana Michailidou,
  • Olga Touloumi,
  • Eleni Polyzoidou,
  • Ilias Salamotas and
  • Nikolaos Grigoriadis
  • + 3 authors

4 May 2024

Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by deficiency of the survival motor neuron (SMN) protein. Although SMA is a genetic disease, environmental factors contribute to disease progression. Common pathogen components such...

  • Article
  • Open Access
28 Citations
5,260 Views
21 Pages

Estimating Occupancy Levels in Enclosed Spaces Using Environmental Variables: A Fitness Gym and Living Room as Evaluation Scenarios

  • Andree Vela,
  • Joanna Alvarado-Uribe,
  • Manuel Davila,
  • Neil Hernandez-Gress and
  • Hector G. Ceballos

18 November 2020

The understanding of occupancy patterns has been identified as a key contributor to achieve improvements in energy efficiency in buildings since occupancy information can benefit different systems, such as HVAC (Heating, Ventilation, and Air Conditio...

  • Article
  • Open Access
2 Citations
4,368 Views
16 Pages

1 December 2021

Quality of care is a complex performance measure of healthcare performance that considers the influence of several contributors. This study enlarges our understanding of how such influences occur. We analyze individual and organizational level charac...

  • Article
  • Open Access
5 Citations
4,071 Views
20 Pages

The integration of sustainability rating systems in healthcare projects and healthcare building envelope specifications is a growing concern in the construction industry, especially in the arid region. The external facade of healthcare buildings is o...

  • Article
  • Open Access
15 Citations
3,120 Views
16 Pages

16 April 2022

Rice-crayfish system has been extensively promoted in China in recent years. However, the presence of toxic elements in soil may threaten the quality of agricultural products. In this study, eight toxic elements were determined in multi-medium includ...

  • Article
  • Open Access
1 Citations
2,208 Views
25 Pages

18 April 2023

In this study, a fuzzy bi-level chance constraint programming (FBCP) model is developed for urban ecological management in Xiamen, China. FBCP has advantages in balancing trade-offs between multiple decision makers and can address fuzzy and stochasti...

  • Article
  • Open Access
3 Citations
1,646 Views
21 Pages

An Analytical Model of IaaS Architecture for Determining Resource Utilization

  • Slawomir Hanczewski,
  • Maciej Stasiak and
  • Michal Weissenberg

26 April 2024

Cloud computing has become a major component of the modern IT ecosystem. A key contributor to this has been the development of Infrastructure as a Service (IaaS) architecture, in which users’ virtual machines (VMs) are run on the service provid...

  • Article
  • Open Access
29 Citations
4,747 Views
24 Pages

22 August 2022

This study aims to design a 16.4 MW photovoltaic solar system located in the Brazilian Northeast and quantify the associated greenhouse gas emissions and environmental payback. The energy system was designed to minimize the Levelized Cost of Energy....

  • Article
  • Open Access
10 Citations
3,334 Views
15 Pages

Cannabinoid CB1 Receptor Deletion from Catecholaminergic Neurons Protects from Diet-Induced Obesity

  • Raj Kamal Srivastava,
  • Inigo Ruiz de Azua,
  • Andrea Conrad,
  • Martin Purrio and
  • Beat Lutz

20 October 2022

High-calorie diets and chronic stress are major contributors to the development of obesity and metabolic disorders. These two risk factors regulate the activity of the sympathetic nervous system (SNS). The present study showed a key role of the canna...

  • Article
  • Open Access
2 Citations
1,468 Views
17 Pages

Endocannabinoid Tone and Oxylipins in Rheumatoid Arthritis and Osteoarthritis—A Novel Target for the Treatment of Pain and Inflammation?

  • Jost Klawitter,
  • Andrew D. Clauw,
  • Jennifer A. Seifert,
  • Jelena Klawitter,
  • Bridget Tompson,
  • Cristina Sempio,
  • Susan L. Ingram,
  • Uwe Christians and
  • Larry W. Moreland

Inflammation is a complicated physiological process that contributes to a variety of disorders including osteoarthritis (OA) and rheumatoid arthritis (RA). Endocannabinoids and the endocannabinoid system (ECS) play a pivotal role in the physiological...

  • Article
  • Open Access
1 Citations
714 Views
10 Pages

Interleukin-2 Receptor as a Marker of Oxidative Stress in Paediatric Patients with Chronic Kidney Disease or Hypertension

  • Nataša Marčun Varda,
  • Mirjam Močnik,
  • Martina Filipič,
  • Evgenija Homšak,
  • Mateja Svetej and
  • Sonja Golob Jančič

28 April 2025

Background/Objectives: Oxidative stress and systemic inflammation are significant contributors to the development and progression of cardiovascular disease, causing adverse effects on vascular health and atherosclerosis from an early age. Patients wi...

  • Article
  • Open Access
21 Citations
5,844 Views
22 Pages

Use of Automated Change Detection and VGI Sources for Identifying and Validating Urban Land Use Change

  • A.-M. Olteanu-Raimond,
  • L. See,
  • M. Schultz,
  • G. Foody,
  • M. Riffler,
  • T. Gasber,
  • L. Jolivet,
  • A. le Bris,
  • Y. Meneroux and
  • M. Gombert
  • + 2 authors

7 April 2020

Land use and land cover (LULC) mapping is often undertaken by national mapping agencies, where these LULC products are used for different types of monitoring and reporting applications. Updating of LULC databases is often done on a multi-year cycle d...

  • Article
  • Open Access
7 Citations
3,018 Views
41 Pages

Comprehensive Resilience Assessment Framework for Water Distribution Networks

  • Joana Carneiro,
  • Dália Loureiro,
  • Marta Cabral and
  • Dídia Covas

14 September 2024

A novel comprehensive resilience assessment framework for drinking water systems is proposed integrating different resilience perspectives (i.e., robustness, autonomy, flexibility, reliability, preparedness and recovery), oriented by objectives, crit...

  • Review
  • Open Access
15 Citations
6,350 Views
18 Pages

RAAS: A Convergent Player in Ischemic Heart Failure and Cancer

  • Texali C. Garcia-Garduño,
  • Jorge R. Padilla-Gutierrez,
  • Diego Cambrón-Mora and
  • Yeminia Valle

The current global prevalence of heart failure is estimated at 64.34 million cases, and it is expected to increase in the coming years, especially in countries with a medium-low sociodemographic index where the prevalence of risk factors is increasin...

  • Article
  • Open Access
3 Citations
2,995 Views
14 Pages

Single-Cell Kinetic Modeling of β-Lapachone Metabolism in Head and Neck Squamous Cell Carcinoma

  • Andrew D. Raddatz,
  • Cristina M. Furdui,
  • Erik A. Bey and
  • Melissa L. Kemp

Head and neck squamous cell carcinoma (HNSCC) cells are highly heterogeneous in their metabolism and typically experience elevated reactive oxygen species (ROS) levels such as superoxide and hydrogen peroxide (H2O2) in the tumor microenvironment. Tum...

  • Article
  • Open Access
4 Citations
1,825 Views
13 Pages

Discordance Between Triglycerides, Remnant Cholesterol and Systemic Inflammation in Patients with Schizophrenia

  • Jeffrey Wang,
  • Maaike Kockx,
  • Gabrielle J. Pennings,
  • Tim Lambert,
  • Vincent Chow and
  • Leonard Kritharides

18 December 2024

Background/Objectives: Hypertriglyceridaemia and systemic inflammation are prevalent in patients with schizophrenia and contribute to an increased risk of cardiovascular disease. Although elevated triglycerides (TGs) and remnant cholesterol are linke...

  • Article
  • Open Access
1,402 Views
19 Pages

8 September 2025

This study demonstrates how mathematical ideas can be developed through genuine applications to problems that are attractive to the learners of mathematics due to consistency with their life experiences. To this end, the paper provides several exampl...

  • Review
  • Open Access
93 Citations
8,750 Views
24 Pages

Migration/Invasion of Malignant Gliomas and Implications for Therapeutic Treatment

  • Ching-Ann Liu,
  • Chia-Yu Chang,
  • Kuo-Wei Hsueh,
  • Hong-Lin Su,
  • Tzyy-Wen Chiou,
  • Shinn-Zong Lin and
  • Horng-Jyh Harn

Malignant tumors of the central nervous system (CNS) are among cancers with the poorest prognosis, indicated by their association with tumors of high-level morbidity and mortality. Gliomas, the most common primary CNS tumors that arise from neuroglia...

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