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25,971 Results Found

  • Article
  • Open Access
44 Citations
8,580 Views
25 Pages

12 January 2022

The severity of the 2007–2008 economic crisis and the spatial heterogeneity of its impact have accelerated the study of regional economic resilience. The economic crisis has affected most parts of the world, and its impact is highly heterogeneo...

(This article belongs to the Collection Economic Inequality, Regional Disparities and Sustainable Development)
  • Article
  • Open Access
3 Citations
1,249 Views
17 Pages

10 October 2025

Background/Objectives: This study analyzes how Health and Fitness Awareness influences quality of life (QOL), mediated by Health Behavior Action and Safety Behavior Practice, within the Social Determinants of Health (SDH) framework. Methods: Accordin...

  • Article
  • Open Access
23 Citations
6,186 Views
24 Pages

Sociodemographic and Regional Determinants of Dietary Patterns in Russia

  • Sergey Maksimov,
  • Natalia Karamnova,
  • Svetlana Shalnova and
  • Oksana Drapkina

An empirical assessment of diets using a posteriori analysis allows us to define actual dietary patterns (DPs) in the food consumption structure of a population. This study represents an a posteriori assessment of DPs for the Russian population in ge...

(This article belongs to the Section Health Behavior, Chronic Disease and Health Promotion)
  • Feature Paper
  • Article
  • Open Access
1,382 Views
15 Pages

1 April 2026

Inclusive insurance plays a critical role in reducing household vulnerability in developing countries such as Indonesia. This study investigates the factors influencing inclusive insurance participation across regencies in the Special Region of Yogya...

  • Article
  • Open Access
6 Citations
1,525 Views
27 Pages

2 November 2025

This study investigates the regional drivers shaping the development of short food supply chains (SFSCs). SFSCs are increasingly recognized as sustainable alternatives to industrial food systems; however, their development dynamics at the regional le...

(This article belongs to the Special Issue Regional Economics, Policies and Sustainable Development)
  • Proceeding Paper
  • Open Access
4 Citations
1,437 Views
15 Pages

Exploring Regional Determinants of Tourism Success in the Eurozone: An Unsupervised Machine Learning Approach

  • Charalampos Agiropoulos,
  • James Ming Chen,
  • George Galanos and
  • Thomas Poufinas

This paper presents an initial analysis of the factors influencing tourism success at the NUTS 2 regional level across the Eurozone from 2010 to 2019. Utilizing an extensive dataset that includes economic, demographic, and tourism-specific indicators...

(This article belongs to the Proceedings of The 10th International Conference on Time Series and Forecasting)
  • Review
  • Open Access
8 Citations
3,813 Views
19 Pages

8 August 2024

The second dose of measles-containing vaccines (MCV2) has significant programmatic relevance in the current immunisation landscape because it serves as both an opportunity to reduce measles immunity gaps and strengthen second year of life vaccination...

(This article belongs to the Special Issue New Insight in Vaccination and Public Health)
  • Article
  • Open Access
1 Citations
1,756 Views
18 Pages

30 April 2025

Traditional high-precision satellite orbits rely on globally dense and evenly distributed ground tracking stations, while the accuracy of precise orbit determination (POD) based on a regional network cannot compare with that of a global network. Low...

  • Review
  • Open Access
51 Citations
6,785 Views
26 Pages

Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Salmonella Serovars

  • Aqsa Shaheen,
  • Anam Tariq,
  • Mazhar Iqbal,
  • Osman Mirza,
  • Abdul Haque,
  • Thomas Walz and
  • Moazur Rahman

26 November 2021

Quinolone resistance in bacterial pathogens has primarily been associated with mutations in the quinolone resistance-determining regions (QRDRs) of bacterial type-II topoisomerases, which are DNA gyrase and topoisomerase IV. Depending on the position...

(This article belongs to the Special Issue Multi-Drug Resistant Gram-Negative Microorganisms: Epidemiology, Treatment and Alternative Approach)
  • Article
  • Open Access
355 Views
15 Pages

15 September 2026

Agricultural cooperatives are widely regarded as engines of rural development, yet their role in advancing the economic, social, and environmental pillars of sustainability within specialized subsectors such as beekeeping remains empirically underexp...

  • Article
  • Open Access
5 Citations
4,925 Views
17 Pages

A Novel Synthetic Antibody Library with Complementarity-Determining Region Diversities Designed for an Improved Amplification Profile

  • Xuelian Bai,
  • Moonseon Jang,
  • Nam Ju Lee,
  • Thi Thu Ha Nguyen,
  • Mooyoung Jung,
  • Jeong Yeon Hwang and
  • Hyunbo Shim

Antibody discovery by phage display consists of two phases, i.e., the binding phase and the amplification phase. Ideally, the selection process is dominated by the former, and all the retrieved clones are amplified equally during the latter. In reali...

(This article belongs to the Special Issue Application of In Silico Techniques in Drug Design)
  • Article
  • Open Access
18 Citations
7,551 Views
15 Pages

This study aims to identify the landscape ecological determinants related to Oncomelania hupensis distribution, map the potential high risk of O. hupensis habitats at the microscale, and assess the effects of two environmental control strategies. Sam...

(This article belongs to the Special Issue Environmental Determinants of Infectious Disease Transmission)
  • Perspective
  • Open Access
25 Citations
8,477 Views
19 Pages

An Opportunity to END TB: Using the Sustainable Development Goals for Action on Socio-Economic Determinants of TB in High Burden Countries in WHO South-East Asia and the Western Pacific Regions

  • Srinath Satyanarayana,
  • Pruthu Thekkur,
  • Ajay M. V. Kumar,
  • Yan Lin,
  • Riitta A. Dlodlo,
  • Mohammed Khogali,
  • Rony Zachariah and
  • Anthony David Harries

The progress towards ending tuberculosis (TB) by 2035 is less than expected in 11 high TB burden countries in the World Health Organization South-East Asia and Western Pacific regions. Along with enhancing measures aimed at achieving universal access...

(This article belongs to the Special Issue Innovation and Evidence for Achieving TB Elimination in the Asia–Pacific Region)
  • Article
  • Open Access
8 Citations
4,245 Views
17 Pages

The Role of Regional Determinants in the Deployment of Renewable Energy in Farms. The Case of Spain

  • María J. Ruiz-Fuensanta,
  • María-Jesús Gutiérrez-Pedrero and
  • Miguel-Ángel Tarancón

25 October 2019

We provide a multilevel logit model based on panel data which allows a capturing of the determinants of investment in their capacity for generating renewable energy in farms. As a novelty, we focus on regional determinants in order to assess the role...

(This article belongs to the Collection Power System and Sustainability)
  • Article
  • Open Access
9 Citations
4,842 Views
19 Pages

Regional Patterns of Pesticide Consumption Determinants in the European Union

  • Raluca Georgiana Robu,
  • Ana-Maria Holobiuc,
  • Alina Petronela Alexoaei,
  • Valentin Cojanu and
  • Dumitru Miron

21 January 2023

This article contributes to the discussion about the socioeconomic factors that reinforce pesticide dependence in the European Union and hinder the transition to more sustainable agricultural practices in light of the European Union’s Green Dea...

(This article belongs to the Special Issue Sustainable Food System in the European Union)
  • Article
  • Open Access
19 Citations
4,009 Views
14 Pages

14 June 2018

Controlling the rapid growth of residential energy demand and enhancing energy efficiency are key policy issues in Japan. Thus, this study aims to estimate a residential energy demand function by conducting a stochastic frontier analysis and analyze...

  • Article
  • Open Access
3 Citations
3,104 Views
18 Pages

High-Throughput Sequencing of Complementarity Determining Region 3 in the Heavy Chain of B-Cell Receptor in Renal Transplant Recipients: A Preliminary Report

  • Tsai-Hung Wu,
  • Hsien-Tzung Liao,
  • Tzu-Hao Li,
  • Hung-Cheng Tsai,
  • Niang-Cheng Lin,
  • Cheng-Yen Chen,
  • Shih-Feng Tsai,
  • Tzu-Hao Huang,
  • Chang-Youh Tsai and
  • Chia-Li Yu

25 May 2022

Background: Graft failure resulting from rejection or any other adverse event usually originates from an aberrant and/or exaggerated immune response and is often catastrophic in renal transplantation. So, it is essential to monitor patients’ im...

(This article belongs to the Special Issue Recent Advances of Kidney Transplantation)
  • Article
  • Open Access
3 Citations
2,029 Views
12 Pages

Dysfunction of Complementarity Determining Region 1 Encoded by T Cell Receptor Beta Variable Gene Is Potentially Associated with African Swine Fever Virus Infection in Pigs

  • Jiayu Li,
  • Huiyan Xing,
  • Kai Liu,
  • Ninglin Fan,
  • Kaixiang Xu,
  • Heng Zhao,
  • Deling Jiao,
  • Taiyun Wei,
  • Wenjie Cheng and
  • Hong-Jiang Wei
  • + 6 authors

The beta T-cell receptor (TRB) expressed by beta T cells is essential for foreign antigen recognition. The TRB locus contains a TRBV family that encodes three complementarity determining regions (CDRs). CDR1 is associated with antigen recognition and...

(This article belongs to the Section Virology)
  • Article
  • Open Access
149 Views
19 Pages

10 October 2026

Background: Fluoroquinolone resistance in methicillin-resistant Staphylococcus aureus (MRSA) involves multiple mechanisms, including quinolone resistance-determining region (QRDR) mutations and efflux pump activity. However, the relationship between...

(This article belongs to the Collection Staphylococcus—Molecular Pathogenesis, Virulence Regulation and Antibiotics Resistance)
  • Article
  • Open Access
3 Citations
3,924 Views
13 Pages

30 March 2024

This study assessed the suitability of the complementarity-determining region 2 (CDR2) of the nanobody (Nb) as a template for the derivation of nanobody-derived peptides (NDPs) targeting active-state β2-adrenergic receptor (β2AR) conformati...

(This article belongs to the Special Issue Functional Peptides and Their Interactions)
  • Article
  • Open Access
3 Citations
2,560 Views
14 Pages

Quinolone Resistance in Gallibacterium anatis Determined by Mutations in Quinolone Resistance-Determining Region

  • Kasper Rømer Villumsen,
  • Toloe Allahghadry,
  • Magdalena Karwańska,
  • Joachim Frey and
  • Anders Miki Bojesen

Control of the important pathogen, Gallibacterium anatis, which causes salpingitis and peritonitis in poultry, relies on treatment using antimicrobial compounds. Among these, quinolones and fluoroquinolones have been used extensively, leading to a ri...

(This article belongs to the Section Mechanism and Evolution of Antibiotic Resistance)
  • Article
  • Open Access
8 Citations
4,652 Views
18 Pages

In this study, official data from Russia’s regions for the period from 2015 to 2019 were analysed on the basis of 12 predictor variables in order to explain the regional raw milk price. Model training and hyperparameter optimisation were perfor...

(This article belongs to the Special Issue The Application of Machine Learning in Agriculture)
  • Article
  • Open Access
3 Citations
2,473 Views
21 Pages

Investigating the IgM and IgG B Cell Receptor Repertoires and Expression of Ultralong Complementarity Determining Region 3 in Colostrum and Blood from Holstein-Friesian Cows at Calving

  • Tess E. Altvater-Hughes,
  • Harold P. Hodgins,
  • Douglas C. Hodgins,
  • Cathy A. Bauman,
  • Marlene A. Paibomesai and
  • Bonnie A. Mallard

2 October 2024

In cattle, colostral maternal immunoglobulins and lymphocytes transfer across the neonate’s intestinal epithelium to provide protection against pathogens. This study aimed to compare repertoires of B cell populations in blood and colostrum in c...

(This article belongs to the Section Cattle)
  • Article
  • Open Access
14 Citations
4,910 Views
22 Pages

23 December 2020

New ventures play an important role in promoting regional economic growth, employment and innovative development. In China, the new business model centered on the sharing economy has grown rapidly in a short time, especially with regard to car-sharin...

(This article belongs to the Collection Sustainable Transport Economics, Behaviour and Policy)
  • Article
  • Open Access
23 Citations
8,310 Views
27 Pages

16 November 2020

Researchers and practitioners argue that in the global context of the Fourth Industrial Revolution, also labelled Industry 4.0, the regional dimension of industrial development remains equally essential. A region that effectively implements the conce...

(This article belongs to the Special Issue Manufacturing Energy Efficiency and Industry 4.0)
  • Article
  • Open Access
13 Citations
7,712 Views
25 Pages

The rapid development of the Chinese economy has stimulated consumer demand and brought huge opportunities for the retail industry. Previous studies have emphasized the importance of estimating regional consumption potentiality. However, the determin...

  • Feature Paper
  • Article
  • Open Access
3 Citations
3,344 Views
11 Pages

3 September 2020

Background. Suicide mortality increased in Greece after the 2008 financial crisis. This study aimed to explore the regional variation of suicide mortality before and after the economic crisis, and its correlation with socio-economic and mental health...

(This article belongs to the Special Issue Epidemiology and Public Health in Applied Sciences)
  • Article
  • Open Access
3 Citations
1,199 Views
26 Pages

24 October 2025

Effective carbon emission control at the provincial level is essential for advancing the high-quality development of the national economy under the “dual carbon” targets. Although Hubei Province is endowed with abundant natural resources...

  • Article
  • Open Access
552 Views
29 Pages

Tourism seasonality remains one of the most persistent structural challenges of Mediterranean destinations, intensifying environmental, economic and social pressures during peak months while leaving tourism capacity underused in the remainder of the...

  • Systematic Review
  • Open Access
10 Citations
2,912 Views
37 Pages

25 November 2025

Accelerating the diffusion of renewable energy requires clear evidence on which determinants enable or hinder deployment across contexts. This study aims to identify the most frequently discussed contemporary determinants of renewable energy deployme...

(This article belongs to the Special Issue Technologies for a Sustainable Future: Towards Sustainable Energy Supply)
  • Article
  • Open Access
6 Citations
5,573 Views
27 Pages

25 April 2019

Traffic calming, as a traffic engineering discipline, is becoming an increasingly important aspect of the road engineering process. One of the traffic calming treatments are pedestrian refuges—raised islands located on or at the road centreline...

(This article belongs to the Special Issue Multi-Criteria Decision-Making Techniques for Improvement Sustainability Engineering Processes)
  • Article
  • Open Access
13 Citations
4,962 Views
19 Pages

Residential energy consumption (REC) has become increasingly important in constructing an energy-saving and environment-friendly society in China. The main purpose of this study is to provide a more in-depth analysis of the determinants of REC from a...

(This article belongs to the Section Environmental Science and Engineering)
  • Article
  • Open Access
8 Citations
3,787 Views
13 Pages

Recently, the signs of extreme droughts, which were thought of as exceptional and unlikely, are being detected worldwide. It is necessary to prepare countermeasures against extreme droughts; however, current definitions of extreme drought are just us...

(This article belongs to the Special Issue Meteorological Extremes in Korea: Prediction, Assessment, and Impact)
  • Article
  • Open Access
3 Citations
4,817 Views
23 Pages

16 February 2017

To provide a reference for risk management of water sources, this study screens the key risk supervision areas around river-type water sources (hereinafter referred to as the water sources) threatened by multiple fixed risk sources (the risk sources)...

(This article belongs to the Section Environmental Sustainability and Applications)
  • Article
  • Open Access
36 Citations
3,942 Views
15 Pages

20 September 2018

It is accepted that improving water efficiency is a key task for China in achieving water sustainability, as the knowledge of water efficiency and its determinants can provide critical information for water policy formulation. To this end, this paper...

(This article belongs to the Special Issue Hydroeconomic Analysis for Sustainable Water Management)
  • Article
  • Open Access
4 Citations
3,282 Views
16 Pages

2 October 2024

Understanding the spatial distribution and sustainable development of rural tourism is essential for promoting balanced regional growth and formulating optimized policy strategies. This study aims to provide insights into sustainable development and...

(This article belongs to the Special Issue Rural Economy and Sustainable Community Development)
  • Article
  • Open Access
8 Citations
3,929 Views
15 Pages

Determinants of Public Knowledge, Attitude, and Practice on Antibiotic Use in Saudi Arabia: A Regional Cross-Sectional Study

  • Wadia S. Alruqayb,
  • Fahad H. Baali,
  • Manar Althbiany,
  • Alanoud Alharthi,
  • Sara Alnefaie,
  • Raghad Alhaji,
  • Reem Alshehri,
  • Wael Y. Khawagi,
  • Monther A. Alshahrani and
  • Abdullah A. Alshehri
  • + 1 author

Background: Antibiotic resistance (AMR) is a critical global and national health challenge, largely driven by the misuse and overuse of antibiotics. Understanding the public′s knowledge and practices regarding antibiotic use is essential for in...

  • Article
  • Open Access
12 Citations
4,589 Views
21 Pages

The Role of Cohesion Policy Funds in Decreasing the Health Gaps Measured by the EURO-HEALTHY Population Health Index

  • Paula Santana,
  • Ângela Freitas,
  • Cláudia Costa,
  • Iwa Stefanik,
  • Gonçalo Santinha,
  • Thomas Krafft and
  • Eva Pilot

Social, economic, and environmental differences across the European Union significantly affect opportunities to move forward in achieving greater equity in health. Cohesion Policy (CP) funds can contribute positively through investments in the main d...

(This article belongs to the Special Issue A More Sustainable and Healthier Future for All: What Works?)
  • Article
  • Open Access
8 Citations
3,825 Views
22 Pages

4 February 2021

This study aimed to explore the state transition of regional innovation capacity (RIC) and analyze the heterogeneous effects of determinants in an innovative subject and environment of RIC state transition based on the data collected from 30 province...

(This article belongs to the Section Economic and Business Aspects of Sustainability)
  • Article
  • Open Access
2 Citations
2,851 Views
10 Pages

Regional Body Composition and Strength, Not Total Body Composition, Are Determinants of Performance in Climbers

  • Fernando Carrasco,
  • Maria Jose Arias-Tellez,
  • Ignacio Solar-Altamirano,
  • Jorge Inostroza and
  • Gabriela Carrasco

Objective: To compare the body composition of Chilean climbers of different performance levels and to determine the relation between the forearm and upper-trunk lean mass and the handgrip and upper-body traction strength, respectively. Methods: A cro...

(This article belongs to the Special Issue Applied Sport Physiology and Performance—4th Edition)
  • Article
  • Open Access
10 Citations
3,264 Views
17 Pages

19 September 2023

Livestock products provide essential micro-nutrients and animal protein to rural residents. Upgrading the consumption pattern of livestock products is not only crucial for improving rural residents’ health and quality of life but also for achie...

(This article belongs to the Special Issue Political and Economic Development in Rural Areas of Developing Countries)
  • Article
  • Open Access
1 Citations
1,395 Views
13 Pages

Double-End Location Technology of Partial Discharge in Cables Based on Frequency-Domain Reflectometry

  • Wang Miao,
  • Hongjing Liu,
  • Ci Song,
  • Hongda Li,
  • Nan He,
  • Jingzhu Teng,
  • Baoqin Cao,
  • Ruonan Bai,
  • Xianglong Li and
  • Haibao Mu

30 July 2025

To realize the region determination and accurate location of cable partial discharge, this paper proposes a cable partial discharge double-end location technique based on frequency-domain reflectometry. The cable partial discharge double-end location...

(This article belongs to the Section Fault Diagnosis & Sensors)
  • Article
  • Open Access
2 Citations
6,153 Views
14 Pages

Effect of Hepatitis C Virus Genotype 1b Core and NS5A Mutations on Response to Peginterferon Plus Ribavirin Combination Therapy

  • Shingo Nakamoto,
  • Fumio Imazeki,
  • Makoto Arai,
  • Shin Yasui,
  • Masato Nakamura,
  • Yuki Haga,
  • Reina Sasaki,
  • Tatsuo Kanda,
  • Hiroshi Shirasawa and
  • Osamu Yokosuka

7 September 2015

We examined whether hepatitis C virus (HCV) genotype 1b core- and NS5A-region mutations are associated with response to peginterferon α-2b plus ribavirin combination therapy. A total of 103 patients with high HCV genotype 1b viral loads (≥100 KIU/mL)...

(This article belongs to the Special Issue Viral Hepatitis Research)
  • Article
  • Open Access
420 Views
27 Pages

Understanding the impact of neighborhood-level factors on stroke prevalence is crucial for addressing existing disparities. However, there is a distinct lack of ecological studies at the census tract level that investigate the social determinants of...

  • Article
  • Open Access
8 Citations
3,378 Views
19 Pages

The Relationship between ROP Funds and Sustainable Development—A Case Study for Poland

  • Łukasz Mach,
  • Karina Bedrunka,
  • Ireneusz Dąbrowski and
  • Paweł Frącz

6 May 2021

The aim of this research is to analyse the correlation between public intervention in Poland within the Regional Operational Programmes and the key macroeconomic variables for the sustainable development of regions, i.e., the labour market, with part...

(This article belongs to the Special Issue Green Economy and Sustainable Development)
  • Article
  • Open Access
1 Citations
1,223 Views
23 Pages

5 March 2026

This study examines the socioeconomic and behavioral determinants, together with spatial heterogeneity, influencing the adoption of solar irrigation pumps in Bangladesh. Five study regions of Bangladesh were sampled using stratified random sampling t...

(This article belongs to the Section Economic and Business Aspects of Sustainability)
  • Communication
  • Open Access
18 Citations
3,622 Views
10 Pages

Immune-Escape Mutations Are Prevalent among Patients with a Coexistence of HBsAg and Anti-HBs in a Tertiary Liver Center in the United States

  • Mukarram Jamat Ali,
  • Pir Ahmed Shah,
  • Khalil Ur Rehman,
  • Satinder Kaur,
  • Vera Holzmayer,
  • Gavin A. Cloherty,
  • Mary C. Kuhns and
  • Daryl T. Y. Lau

30 April 2024

The concurrent seropositivity of HBsAg and anti-HBs has been described among patients with chronic hepatitis B (CHB), but its prevalence is variable. HBV S-gene mutations can affect the antigenicity of HBsAg. Patients with mutations in the ‘&al...

(This article belongs to the Special Issue Viral Genetic Variation)
  • Article
  • Open Access
2 Citations
1,862 Views
27 Pages

22 June 2025

Carbon transfer embodies the spatial redistribution of carbon emissions resulting from interregional economic activities and trade. In recent years, accelerated regional integration and deepening specialization within industrial chains have rendered...

  • Article
  • Open Access
21 Citations
2,277 Views
15 Pages

Upper Bounds of the Third Hankel Determinant for Bi-Univalent Functions in Crescent-Shaped Domains

  • Qasim Ali Shakir,
  • Adel Salim Tayyah,
  • Daniel Breaz,
  • Luminita-Ioana Cotîrlă,
  • Eleonora Rapeanu and
  • Fethiye Müge Sakar

29 September 2024

This paper investigates the third Hankel determinant, denoted H3(1), for functions within the subclass RS∑*(λ) of bi-univalent functions associated with crescent-shaped regions φ⦅z=z+1+z2. The primary aim of this study is to est...

(This article belongs to the Section B: Mathematics)
  • Article
  • Open Access
4 Citations
1,891 Views
11 Pages

21 May 2024

In Apis mellifera, csd is the primary gene involved in sex determination: haploid hemizygous eggs develop as drones, while females develop from eggs heterozygous for the csd gene. If diploid eggs are homozygous for the csd gene, diploid drones will d...

(This article belongs to the Section Animal Genetics and Genomics)

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