- Article
Nitro-Oleic Acid (NO2-OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis
- Simon Braumann,
- Wibke Schumacher,
- Nam Gyu Im,
- Felix Sebastian Nettersheim,
- Dennis Mehrkens,
- Senai Bokredenghel,
- Alexander Hof,
- Richard Julius Nies,
- Christoph Adler and
- Simon Geißen
- + 8 authors
Nitro-oleic acid (NO2-OA), a nitric oxide (NO)- and nitrite (NO2−)-derived electrophilic fatty acid metabolite, displays anti-inflammatory and anti-fibrotic signaling actions and therapeutic benefit in murine models of ischemia-reperfusion, atrial fi...