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14,953 Results Found

  • Article
  • Open Access
264 Views
17 Pages

Developing an Index to Measure Structural Racism: Methodological Process, Challenges, and Considerations

  • Christopher M. Amissah,
  • Alisha A. Crump,
  • Yu-Hua Fu,
  • Sheela Khadka,
  • Jennifer Contreras,
  • Salene M. W. Jones,
  • Bryce B. Reeve and
  • Ester Villalonga-Olives

Access to valid and reliable measures of structural racism is essential for addressing health inequities, yet few validated ecological-level indices exist for assessing structural racism affecting Black and Hispanic populations in the United States....

  • Article
  • Open Access
8 Citations
3,256 Views
16 Pages

In 2017, Quebec’s Auditor General reported several major issues regarding government-funded French as a second language (FSL) courses, especially those intended for adult students with limited or interrupted formal education (SLIFE). To this da...

  • Project Report
  • Open Access
1 Citations
1,856 Views
12 Pages

Methodological and Practical Challenges in Synthesizing Occupational Cancer Studies

  • Soyeon Ahn,
  • Laura A. McClure,
  • Paulo S. Pinheiro,
  • Diana Hernandez,
  • Devina J. Boga,
  • Henna Ukani,
  • Jennifer V. Chavez,
  • Jorge A. Quintela Fernandez,
  • Alberto J. Caban-Martinez and
  • David J. Lee
  • + 1 author

Studies examining occupational exposures and cancer risk frequently report mixed findings; it is thus imperative for researchers to synthesize study results and identify any potential sources that explain such variabilities in study findings. However...

  • Communication
  • Open Access
1 Citations
3,906 Views
13 Pages

Methodological Challenges in Studying Trust in Natural Resources Management

  • Antonia Sohns,
  • Gordon M. Hickey,
  • Jasper R. de Vries and
  • Owen Temby

26 November 2021

Trust has been identified as a central characteristic of successful natural resource management (NRM), particularly in the context of implementing participatory approaches to stakeholder engagement. Trust is, however, a multi-dimensional and multi-le...

  • Review
  • Open Access
24 Citations
7,866 Views
13 Pages

17 February 2017

Islands across the world have evolved at the interface between land and sea, thus comprising landscapes and seascapes. Many islands have also been influenced by anthropogenic factors, which have given rise to mosaics of anthromes (sensu Ellis and Ram...

  • Article
  • Open Access
3,044 Views
11 Pages

18 October 2023

In Romania, the neo-pagan communities are being organized and are working to define their identity in the middle of a Christian environment. In turn, individuals claiming to be neopagans begin to assert themselves in the public space. While the neopa...

  • Article
  • Open Access
1 Citations
1,998 Views
16 Pages

25 June 2024

This article is methodological in nature, addressing and discussing the challenges the research team encountered in constructing a new international well-being index called the World Love Index. This index represents the first quantitative operationa...

  • Review
  • Open Access
77 Citations
9,771 Views
15 Pages

Digital Twins in Healthcare: Methodological Challenges and Opportunities

  • Charles Meijer,
  • Hae-Won Uh and
  • Said el Bouhaddani

23 October 2023

One of the most promising advancements in healthcare is the application of digital twin technology, offering valuable applications in monitoring, diagnosis, and development of treatment strategies tailored to individual patients. Furthermore, digital...

  • Review
  • Open Access
5 Citations
5,432 Views
17 Pages

The investigation of the phenomenology of autobiographical memories (i.e., how a memory is subjectively experienced and its meaning) has provided an important contribution to our understanding of autobiographical remembering. Over the last two decade...

  • Feature Paper
  • Article
  • Open Access
17 Citations
5,523 Views
9 Pages

Economic Evaluation of Environmental Interventions: Reflections on Methodological Challenges and Developments

  • Laura Bojke,
  • Laetitia Schmitt,
  • James Lomas,
  • Gerry Richardson and
  • Helen Weatherly

Evaluation of the costs and outcomes associated with environmental policies and interventions is often required to inform public policy and allocate scarce resources. Methods to conduct assessments of cost-effectiveness have been developed in the con...

  • Article
  • Open Access
10 Citations
4,173 Views
20 Pages

The Methodological Quality and Challenges in Conducting Economic Evaluations of Newborn Screening: A Scoping Review

  • Pasquale Cacciatore,
  • Laurenske A. Visser,
  • Nasuh Buyukkaramikli,
  • Catharina P. B. van der Ploeg and
  • M. Elske van den Akker-van Marle

Cost-effectiveness (CEA) and cost–utility analyses (CUA) have become popular types of economic evaluations (EE) used for evidence-based decision-making in healthcare resource allocation. Newborn screening programs (NBS) can have significant cli...

  • Review
  • Open Access
50 Citations
3,797 Views
14 Pages

Oncologic Imaging and Radiomics: A Walkthrough Review of Methodological Challenges

  • Arnaldo Stanzione,
  • Renato Cuocolo,
  • Lorenzo Ugga,
  • Francesco Verde,
  • Valeria Romeo,
  • Arturo Brunetti and
  • Simone Maurea

5 October 2022

Imaging plays a crucial role in the management of oncologic patients, from the initial diagnosis to staging and treatment response monitoring. Recently, it has been suggested that its importance could be further increased by accessing a new layer of...

  • Article
  • Open Access
9 Citations
5,354 Views
14 Pages

This paper offers a critical appraisal of the methodological capacity of Discourse Studies (DS) in conducting urban research. Based on an extensive literature search, 125 publications that explicitly claim to utilise DS were reviewed. The results sho...

  • Article
  • Open Access
2 Citations
2,719 Views
16 Pages

4 April 2023

In recent decades, the landscape has given a new impulse to the renewal of spatial planning. This process has nevertheless raised several methodological issues about how to deal with sensitive non-functional aspects in spatial planning tools and proc...

  • Review
  • Open Access
2 Citations
3,379 Views
25 Pages

A Narrative Review of Life Cycle Assessments of Electric Vehicles: Methodological Challenges and Global Implications

  • Monika Zajemska,
  • Anna Biniek-Poskart,
  • Andrzej Skibiński,
  • Magdalena Skrzyniarz and
  • Jakub Rzącki

30 October 2025

Considering the rapid global shift towards electric mobility and the growing importance of life-cycle assessments (LCAs) in policy and investment decisions, a critical examination of the methodological challenges and broader implications of electric...

  • Review
  • Open Access
6 Citations
8,903 Views
19 Pages

Artificial Intelligence in Medical Education: A Narrative Review on Implementation, Evaluation, and Methodological Challenges

  • Annalisa Roveta,
  • Luigi Mario Castello,
  • Costanza Massarino,
  • Alessia Francese,
  • Francesca Ugo and
  • Antonio Maconi

11 September 2025

Artificial Intelligence (AI) is rapidly transforming medical education by enabling adaptive tutoring, interactive simulation, diagnostic enhancement, and competency-based assessment. This narrative review explores how AI has influenced learning proce...

  • Review
  • Open Access
13 Citations
3,938 Views
25 Pages

27 April 2021

Cascade genetic testing is indicated for family members of individuals testing positive on a genetic test, and is particularly relevant for child health because of their vulnerability and the long-term health and economic implications. Cascade testin...

  • Review
  • Open Access
2,496 Views
33 Pages

Longitudinal research provides critical insights into the evolving health trajectories of immigrants, capturing changes from initial arrival through to long-term settlement. However, longitudinal studies on immigrant health in Canada face persistent...

  • Review
  • Open Access
5 Citations
10,612 Views
20 Pages

Systematic reviews require labor-intensive screening processes—an approach prone to bottlenecks, delays, and scalability constraints in large-scale reviews. Large Language Models (LLMs) have recently emerged as a powerful alternative, capable o...

  • Review
  • Open Access
20 Citations
8,537 Views
30 Pages

Mapping South America’s Drylands through Remote Sensing—A Review of the Methodological Trends and Current Challenges

  • Khalil Ali Ganem,
  • Yongkang Xue,
  • Ariane de Almeida Rodrigues,
  • Washington Franca-Rocha,
  • Marceli Terra de Oliveira,
  • Nathália Silva de Carvalho,
  • Efrain Yury Turpo Cayo,
  • Marcos Reis Rosa,
  • Andeise Cerqueira Dutra and
  • Yosio Edemir Shimabukuro

4 February 2022

The scientific grasp of the distribution and dynamics of land use and land cover (LULC) changes in South America is still limited. This is especially true for the continent’s hyperarid, arid, semiarid, and dry subhumid zones, collectively known...

  • Article
  • Open Access
3 Citations
1,980 Views
23 Pages

Challenges That Need to Be Addressed before Starting New Emergency Remote Teaching at HEIs and Proposed Solutions

  • Simona Šinko,
  • Joan Navarro,
  • Xavier Solé-Beteta,
  • Agustín Zaballos and
  • Brigita Gajšek

29 January 2024

Emergency Remote Teaching (ERT) aims to swiftly adapt conventional face-to-face educational methods to alternative (typically virtual) formats during crises. The recent COVID-19 pandemic accentuated the vulnerability of traditional educational system...

  • Article
  • Open Access
351 Views
18 Pages

Considering the challenges of decarbonization, the energy transition, and the necessity to increase resource efficiency in the context of the circular economy, there is a need to develop sustainable solutions for the material and energy use of biogen...

  • Article
  • Open Access
1 Citations
1,390 Views
32 Pages

23 November 2023

The main objective of this research is to describe a multidisciplinary investigation part of an ongoing research project. The contribution focuses on the identification and selection of innovative technologies and operative methodologies capable of f...

  • Review
  • Open Access
6 Citations
5,061 Views
25 Pages

5′-UTR G-Quadruplex-Mediated Translation Regulation in Eukaryotes: Current Understanding and Methodological Challenges

  • Polina N. Kamzeeva,
  • Vera A. Alferova,
  • Vladimir A. Korshun,
  • Anna M. Varizhuk and
  • Andrey V. Aralov

30 January 2025

RNA G-quadruplexes (rG4s) in 5′-UTRs represent complex regulatory elements capable of both inhibiting and activating mRNA translation through diverse mechanisms in eukaryotes. This review analyzes the evolution of our understanding of 5′-...

  • Article
  • Open Access
5 Citations
4,664 Views
28 Pages

2 October 2021

The EU Biodiversity Strategy for 2020 was a driving force behind spatially explicit quantifications of Ecosystem Services (ES) in Europe. In Portugal, the MAES initiative (ptMAES–Mapping and Assessment of Ecosystem and their Services) was conducted i...

  • Article
  • Open Access
9 Citations
8,342 Views
33 Pages

10 February 2021

Mobile application development is a highly competitive environment; agile methodologies can enable teams to provide value faster, with higher quality and predictability, and a better attitude to deal with the continuous changes that will arise in the...

  • Article
  • Open Access
6 Citations
3,895 Views
13 Pages

21 August 2020

This article analyzes the challenges faced by the inhabitants of the island of Rapa Nui in connection with climate change-related environmental and socio-economic problems, and the survival of the islanders’ cultural identity and their very sus...

  • Review
  • Open Access
40 Citations
9,586 Views
28 Pages

Dithiocarbamates: Properties, Methodological Approaches and Challenges to Their Control

  • Claudia Campanale,
  • Mariangela Triozzi,
  • Annamaria Ragonese,
  • Daniela Losacco and
  • Carmine Massarelli

11 October 2023

Dithiocarbamates (DTCs) are a group of chemicals used primarily as fungicides, although they are exploited for various other applications. DTCs represent one of the oldest classes of broad-spectrum fungicides employed worldwide to control fungal dise...

  • Editorial
  • Open Access
4 Citations
9,855 Views
10 Pages

19 February 2020

Electoral psychology is defined as any model based on human psychology that is used to explain any electoral experience or outcome at the individual or aggregate level. Electoral psychology can also be an interface with other crucial aspects of the v...

  • Article
  • Open Access
834 Views
19 Pages

In mathematics, and in learning mathematics, representations (texts, formulae, and figures) play a vital role. Eye-tracking is a promising approach for studying how representations are attended to in the context of mathematics learning. The focus of...

  • Article
  • Open Access
20 Citations
9,047 Views
16 Pages

7 November 2019

Children with autism spectrum disorders often suffer from poor school inclusion, loneliness, and poor quality of life. Suitable support options for overcoming these risks are lacking, partly because children’s perspectives concerning their supp...

  • Article
  • Open Access
12 Citations
4,662 Views
18 Pages

EXPLORIA, STEAM Education at University Level as a New Way to Teach Engineering Mechanics in an Integrated Learning Process

  • Nicolás Montés,
  • Paula Aloy,
  • Teresa Ferrer,
  • Pantaleon D. Romero,
  • Sara Barquero and
  • Alfonso Martinez Carbonell

19 May 2022

The objective of our research is the implementation of STEAM (Science Technology Engineering Art Mathematics) learning in the bachelor of Engineering in industrial design and product development at CEU Cardenal Herrera University through the EXPLORIA...

  • Article
  • Open Access
6 Citations
3,277 Views
18 Pages

The Equilibrium Challenge, a New Way to Teach Engineering Mechanics in Architecture Degrees

  • Nicolás Montés,
  • Lucía Hilario,
  • Javier Rivera,
  • Ángel López,
  • Teresa Ferrer,
  • Pedro Verdejo,
  • Ignacio Juan and
  • Ana Ábalos

14 April 2023

Vocation is one of the determining factors taken into account by students when choosing their university studies. However, when the students start their studies, in their first year, they will find a series of basic subjects that barely motivate or s...

  • Article
  • Open Access
5 Citations
4,480 Views
22 Pages

Nutritional Inadequacy: Unraveling the Methodological Challenges for the Application of the Probability Approach or the EAR Cut-Point Method—A Pregnancy Perspective

  • Foteini Tsakoumaki,
  • Charikleia Kyrkou,
  • Apostolos P. Athanasiadis,
  • Georgios Menexes and
  • Alexandra-Maria Michaelidou

29 September 2021

The aim of this study was to unravel the methodological challenges when exploring nutritional inadequacy, involving 608 healthy pregnant women. The usual intake of twenty-one nutrients was recorded by employing a validated FFQ. Simulated datasets of...

  • Article
  • Open Access
2 Citations
1,367 Views
20 Pages

14 June 2025

The living lab methodology is widely used in innovation projects to drive user-centered development. While its benefits, such as co-creation and real-world validation, are well known, its implementation presents challenges that remain underexplored....

  • Review
  • Open Access
3,191 Views
24 Pages

Environmental DNA Metabarcoding in Marine Ecosystems: Global Advances, Methodological Challenges, and Applications in the MENA Region

  • Sandy K. Sawh,
  • Sarah Merabet,
  • Nayla Higazy,
  • Marwa Béji,
  • Johan Mølgård Sørensen,
  • Pedro Range,
  • Ahmad M. Alqudah and
  • Mohamed Nejib Daly Yahia

22 October 2025

Environmental DNA (eDNA) metabarcoding has transformed marine biodiversity monitoring by allowing non-invasive, cost-effective detection of species with high resolution across diverse marine habitats. A systematic literature search was conducted usin...

  • Review
  • Open Access
1 Citations
4,754 Views
26 Pages

13 August 2025

Since 2005, landscape ecology has emerged as a structured scientific field in the Democratic Republic of Congo, notably shaped by the contributions of Professor Jan Bogaert. The evolution of research in this field can be divided into three main phase...

  • Review
  • Open Access
6 Citations
2,774 Views
20 Pages

Chitosan as an Elicitor in Plant Tissue Cultures: Methodological Challenges

  • Moumita Roy Chowdhury,
  • Mizgin Mehmet,
  • Jit Mukherjee,
  • Anirban Jyoti Debnath and
  • Katarína Ražná

24 August 2025

Chitosan (CTS) is a biodegradable and biocompatible biopolymer derived from chitin. Thanks to its diverse biological activities and environmentally friendly nature, it has emerged as a promising agent in plant tissue culture. Recent studies have high...

  • Review
  • Open Access
35 Citations
6,822 Views
26 Pages

Risk Assessment of Combined Exposure to Multiple Chemicals at the European Food Safety Authority: Principles, Guidance Documents, Applications and Future Challenges

  • Irene Cattaneo,
  • Alexander D. Kalian,
  • Matteo R. Di Nicola,
  • Bruno Dujardin,
  • Sara Levorato,
  • Luc Mohimont,
  • Alexis V. Nathanail,
  • Edoardo Carnessechi,
  • Maria Chiara Astuto and
  • Jean Lou C. M. Dorne
  • + 7 authors

4 January 2023

Human health and animal health risk assessment of combined exposure to multiple chemicals use the same steps as single-substance risk assessment, namely problem formulation, exposure assessment, hazard assessment and risk characterisation. The main u...

  • Article
  • Open Access
3 Citations
6,097 Views
18 Pages

Addressing Challenges When Applying GRADE to Public Health Guidelines: A Scoping Review Protocol and Pilot Analysis

  • Lucia Kantorová,
  • Tereza Friessová,
  • Simona Slezáková,
  • Alena Langaufová,
  • Jiří Kantor,
  • Zachary Munn,
  • Timothy Hugh Barker,
  • Srinivasa Vittal Katikireddi,
  • Reem A. Mustafa and
  • Miloslav Klugar
  • + 13 authors

This is a protocol for a scoping review that aims to determine how guideline authors using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach have addressed previously identified challenges related to public hea...

  • Article
  • Open Access
22 Citations
7,549 Views
17 Pages

The Impact of a Challenge-Based Learning Experience in Physical Education on Students’ Motivation and Engagement

  • Luis Simón-Chico,
  • Alba González-Peño,
  • Ernesto Hernández-Cuadrado and
  • Evelia Franco

The present study investigated how challenge-based learning (CBL) in physical education (PE) may affect students’ basic psychological needs (BPNs), motivational regulations, engagement, and learning in comparison with a traditional teaching (TT...

  • Review
  • Open Access
14 Citations
6,450 Views
26 Pages

Cancer Stem Cells in Oral Squamous Cell Carcinoma: A Narrative Review on Experimental Characteristics and Methodological Challenges

  • Surendra Kumar Acharya,
  • Saptarsi Shai,
  • Yee Fan Choon,
  • Indrayadi Gunardi,
  • Firstine Kelsi Hartanto,
  • Kathreena Kadir,
  • Ajoy Roychoudhury,
  • Rahmi Amtha and
  • Vui King Vincent-Chong

16 September 2024

Cancer stem cells (CSCs) represent a subpopulation of cancer cells that are believed to initiate and drive cancer progression. In animal models, xenotransplanted CSCs have demonstrated the ability to produce tumors. Since their initial isolation in b...

  • Article
  • Open Access
2,468 Views
21 Pages

6 June 2025

This article offers a critical methodological reflection on the use of poetry workshops in migration research, positioning them as empowering, ethically complex, yet powerful research tools for studying migrant experience. While arts-based methods ha...

  • Feature Paper
  • Review
  • Open Access
25 Citations
7,080 Views
22 Pages

Life Cycle Assessment Applied to Nature-Based Solutions: Learnings, Methodological Challenges, and Perspectives from a Critical Analysis of the Literature

  • Pyrène Larrey-Lassalle,
  • Stéphanie Armand Decker,
  • Domenico Perfido,
  • Serkan Naneci and
  • Benedetto Rugani

27 April 2022

The use of life cycle assessment (LCA) allows work to go beyond the traditional scope of urban nature-based solutions (NBS), in which ecosystem services are provided to citizens, to include environmental impacts generated over the entire life cycle o...

  • Feature Paper
  • Review
  • Open Access
9 Citations
6,953 Views
34 Pages

Boar Sperm Motility Assessment Using Computer-Assisted Sperm Analysis: Current Practices, Limitations, and Methodological Challenges

  • Lenka Hackerova,
  • Aneta Pilsova,
  • Zuzana Pilsova,
  • Natalie Zelenkova,
  • Pavla Tymich Hegrova,
  • Barbora Klusackova,
  • Eva Chmelikova,
  • Marketa Sedmikova,
  • Ondrej Simonik and
  • Pavla Postlerova

22 January 2025

Spermatozoa are highly specialized male cells that are characterized by a unique ability to move, which is a critical factor for successful fertilization. The relative simplicity of motility assessment, especially in livestock, has made it a widely u...

  • Review
  • Open Access
35 Citations
4,261 Views
18 Pages

Challenges in the Use of AI-Driven Non-Destructive Spectroscopic Tools for Rapid Food Analysis

  • Wenyang Jia,
  • Konstantia Georgouli,
  • Jesus Martinez-Del Rincon and
  • Anastasios Koidis

10 March 2024

Routine, remote, and process analysis for foodstuffs is gaining attention and can provide more confidence for the food supply chain. A new generation of rapid methods is emerging both in the literature and in industry based on spectroscopy coupled wi...

  • Article
  • Open Access
5 Citations
3,206 Views
15 Pages

11 January 2024

Migrants of non-European origin tend to suffer more from diabetes, obesity and other chronic ailments compared to the native population. A group of female Turkish migrants in ill health, living in Denmark, were invited to join a session of eleven wee...

  • Review
  • Open Access
9 Citations
7,166 Views
23 Pages

9 November 2020

In recent years, the focus in safety management has shifted from failure-based analysis towards a more systemic perspective, redefining a successful or failed performance as a complex and emergent event rather than as a conclusion of singular errors...

  • Article
  • Open Access
4 Citations
2,769 Views
10 Pages

29 November 2021

Environmental education research needs to take into account the relational dimension of the ecological challenges of our time. It requires the development of methodological techniques that prioritize community concerns, and generally foster positive...

  • Review
  • Open Access
4 Citations
3,448 Views
15 Pages

Conceptual Cartography for the Systematic Study of Music Education Based on ICT or EdTech

  • Antonio León-Garrido,
  • Julio Manuel Barroso-Osuna and
  • Carmen Llorente-Cejudo

30 September 2022

Music and its study have always been present among people. Its learning is significant, as it provides benefits and helps in the acquisition of many abilities and skills. However, didactic, methodological, and pedagogical changes have begun to appear...

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