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1,745 Results Found

  • Article
  • Open Access
19 Citations
6,313 Views
10 Pages

Light Stimulation Parameters Determine Neuron Dynamic Characteristics

  • Alexander Erofeev,
  • Evgenii Gerasimov,
  • Anastasia Lavrova,
  • Anastasia Bolshakova,
  • Eugene Postnikov,
  • Ilya Bezprozvanny and
  • Olga L. Vlasova

5 September 2019

Optogenetics is a recently developed technique that is widely used to study neuronal function. In optogenetic experiments, neurons encode opsins (channelrhodopsins, halorhodopsins or their derivatives) by means of viruses, plasmids or genetic modific...

  • Article
  • Open Access
2 Citations
2,762 Views
17 Pages

Eye stimulation research plays a critical role in advancing our understanding of visual processing and developing new therapies for visual impairments. Despite its importance, researchers and clinicians still face challenges with the availability of...

  • Article
  • Open Access
1 Citations
3,072 Views
19 Pages

Analysis of Electric Field Stimulation in Blue Light Stressed 661W Cells

  • Sharanya Bola,
  • Pallavi Subramanian,
  • Daniela Calzia,
  • Andreas Dahl,
  • Isabella Panfoli,
  • Richard H. W. Funk and
  • Cora Roehlecke

8 February 2023

Though electrical stimulation is used as a therapeutic approach to treat retinal and spinal injuries, many protective mechanisms at cellular level have not been elucidated. We performed a detailed analysis of cellular events in blue light (Li) stress...

  • Article
  • Open Access
6 Citations
3,146 Views
13 Pages

Pre-Sowing Laser Light Stimulation Increases Yield and Protein and Crude Fat Contents in Soybean

  • Agnieszka Klimek-Kopyra,
  • Reinhard W. Neugschwandtner,
  • Anna Ślizowska,
  • Dominika Kot,
  • Jan Wincenty Dobrowolski,
  • Zbigniew Pilch and
  • Ewa Dacewicz

20 September 2022

Pre-sowing laser light stimulation is a method commonly used to increase the productivity of legume species. However, it has not been proved that single-laser light stimulation is a more effective technique for enhancing plant productivity and seed y...

  • Article
  • Open Access
1 Citations
1,802 Views
16 Pages

13 August 2023

The output signal from a photoacoustic cell based on a symmetrical Helmholtz resonator structure can be substantially increased if a counterphase light stimulation is applied to the cell cavities. However even slight differences in the intensity of t...

  • Review
  • Open Access
9 Citations
4,344 Views
28 Pages

Progress, Opportunities, and Challenges of Magneto-Plasmonic Nanoparticles under Remote Magnetic and Light Stimulation for Brain-Tissue and Cellular Regeneration

  • Muzhaozi Yuan,
  • Mackenzie Caitlin Harnett,
  • Tian-Hao Yan,
  • Elias Georgas,
  • Yi-Xian Qin,
  • Hong-Cai Zhou and
  • Ya Wang

29 June 2022

Finding curable therapies for neurodegenerative disease (ND) is still a worldwide medical and clinical challenge. Recently, investigations have been made into the development of novel therapeutic techniques, and examples include the remote stimulatio...

  • Article
  • Open Access
2,866 Views
19 Pages

Green Light and Transcranial Direct Current Stimulation in Migraine Patients: A Preliminary Randomized Control Trial

  • Amna Mahmood,
  • Mirza Obaid Baig,
  • Sumaiyah Obaid,
  • Turki Abualait and
  • Shahid Bashir

9 November 2025

Background: Migraine is a complex neurological condition characterized by a range of symptoms, such as intense to severe headaches, sensitivity to light and sound, and feelings of nausea and vomiting. The most common complaints regarding acute treatm...

  • Article
  • Open Access
13 Citations
6,782 Views
19 Pages

Photobiological Neuromodulation of Resting-State EEG and Steady-State Visual-Evoked Potentials by 40 Hz Violet Light Optical Stimulation in Healthy Individuals

  • Yoshihiro Noda,
  • Mayuko Takano,
  • Motoshi Hayano,
  • Xuemei Li,
  • Masataka Wada,
  • Shinichiro Nakajima,
  • Masaru Mimura,
  • Shinichiro Kondo and
  • Kazuo Tsubota

15 June 2021

Photobiological neuromodulation and its clinical application has been investigated in recent years. The response of the gamma-oscillation to human visual stimuli is known to be both burst and resonant in nature, and the coupling between alpha and gam...

  • Article
  • Open Access
12 Citations
3,304 Views
16 Pages

19 March 2021

The study aimed to determine the impact of laser light (L), magnetic stimulation (p) and silver nanocolloid (AgNC) on pumpkin seeds on the germination rate and content of photosynthetic pigments as well as the efficiency of photosynthesis and greenne...

  • Review
  • Open Access
3 Citations
3,880 Views
25 Pages

Review on Multispectral Photoacoustic Imaging Using Stimulated Raman Scattering Light Sources

  • Yuon Song,
  • Sang Min Park,
  • Yongjae Jeong,
  • Jeesu Kim and
  • Hwidon Lee

25 May 2025

Photoacoustic imaging is an advanced biomedical imaging technique that has been widely developed and applied in diverse biomedical studies. By generating optical-absorption-based signals with ultrasound resolution, it enables in vivo visualization of...

  • Article
  • Open Access
2 Citations
2,553 Views
11 Pages

20 November 2020

A novel temperature sensor designed on stimulate Brillouin scattering fast light in liquid-filled photonic crystal fibers is proposed. The time advancement and the Brillouin frequency shift of fast light are simulated according to the three-wave coup...

  • Article
  • Open Access
1,841 Views
14 Pages

Blue-Light Stimulation for Myopia Prevention: Only Retinal but Not Optic Disc Stimulation Modulates the Pattern ERG

  • Isabella Silke Elisabeth Mehler,
  • Sven Pascal Heinrich,
  • Daniel Böhringer,
  • Valentin Simon,
  • Tim Bleul,
  • Sebastian Küchlin,
  • Wolf Alexander Lagrèze and
  • Navid Farassat

1 September 2025

Blue-light stimulation of the optic disc has been suggested as a means of myopia prevention by activating dopaminergic amacrine cells via intrinsically photosensitive retinal ganglion cells. This prospective, adequately powered study investigated thi...

  • Article
  • Open Access
1 Citations
3,057 Views
18 Pages

The balance between cortical excitation and inhibition (E/I balance) in the cerebral cortex is critical for cognitive processing and neuroplasticity. Modulation of this balance has been linked to a wide range of neuropsychiatric and neurodegenerative...

  • Article
  • Open Access
5 Citations
4,264 Views
17 Pages

Responses to Intermittent Light Stimulation Late in the Night Phase Before Dawn

  • Sevag Kaladchibachi,
  • David C. Negelspach and
  • Fabian Fernandez

27 September 2018

The circadian clock is comprised of two oscillators that independently track sunset (evening) and sunrise (morning), though little is known about how light responses differ in each. Here, we quantified the morning oscillator’s responses to 19 s...

  • Article
  • Open Access
2 Citations
3,538 Views
13 Pages

Retinal Phosphenes Induced by Transorbital Electrical Stimulation: Influence of Light Adaptation, Electrode Montage, and View Direction

  • Alexander Hunold,
  • Daniela Ortega,
  • Stefanie Freitag,
  • Dietmar Link,
  • Andrea Antal,
  • Sascha Klee and
  • Jens Haueisen

21 May 2025

In this study, the perception of phosphenes was used as a surrogate identifier for stimulation sites for use in retinal-degenerative diseases. We aimed to investigate the influence of adaptation, electrode montage, and direction of view on electrical...

  • Review
  • Open Access
1 Citations
1,186 Views
22 Pages

1 September 2025

In mammals, the suprachiasmatic nucleus (SCN), located in the hypothalamus serves as the master biological clock and precisely regulates circadian rhythms through a complex network structure. As a central pacemaker, the SCN has two primary functions:...

  • Article
  • Open Access
21 Citations
5,769 Views
9 Pages

Early- and Late-Light Embryonic Stimulation Modulates Similarly Chicks’ Ability to Filter out Distractors

  • Cinzia Chiandetti,
  • Bastien S. Lemaire,
  • Elisabetta Versace and
  • Giorgio Vallortigara

8 June 2017

Chicks (Gallus gallus) learned to run from a starting box to a target located at the end of a runway. At test, colourful and bright distractors were placed just outside the starting box. Dark incubated chicks (maintained in darkness from fertilizatio...

  • Article
  • Open Access
2 Citations
2,168 Views
16 Pages

β-actin belongs to cytoskeletal structures that change dynamically in cells according to various stimuli. Human skin can be considered as an organ that is very frequently exposed to various stress factors, of which light plays an important role....

  • Communication
  • Open Access
1 Citations
2,683 Views
5 Pages

A Compact Avalanche-Transistor-Based Pulse Generator for Transcranial Infrared Light Stimulation (TILS) Experiments

  • Abraham Lopez,
  • Haley N. Strong,
  • Kendra I. McGlothen,
  • Dustin J. Hines and
  • R. Jacob Baker

A pulse generator using an avalanche transistor operating in current-mode second breakdown driving a 780 nm laser diode is reported. The laser diode is mounted on the skull of a mouse and used in transcranial infrared light stimulation (TILS) experim...

  • Article
  • Open Access
33 Citations
7,731 Views
14 Pages

Optogenetic Stimulation of Human Neural Networks Using Fast Ferroelectric Spatial Light Modulator—Based Holographic Illumination

  • Felix Schmieder,
  • Simon D. Klapper,
  • Nektarios Koukourakis,
  • Volker Busskamp and
  • Jürgen W. Czarske

19 July 2018

The generation and application of human stem-cell-derived functional neural circuits promises novel insights into neurodegenerative diseases. These networks are often studied using stem-cell derived random neural networks in vitro, with electrical st...

  • Review
  • Open Access
10 Citations
5,707 Views
22 Pages

17 March 2020

In this review article, we are going to present an overview on possible applications of light-addressable electrodes (LAE) as actuator/manipulation devices besides classical electrode structures. For LAEs, the electrode material consists of a semicon...

  • Article
  • Open Access
2 Citations
3,377 Views
12 Pages

Light-Dependent Effects of Prefrontal rTMS on Emotional Working Memory

  • Anne Weigand,
  • Lisa Edelkraut,
  • Markus Conrad,
  • Simone Grimm and
  • Malek Bajbouj

Growing evidence suggests that colored light exposure can affect several brain functions in addition to conscious visual perception. Blue as compared to green light has especially been shown to enhance alertness and vigilance, as well as cognitive fu...

  • Article
  • Open Access
3 Citations
2,214 Views
13 Pages

The BcWCL1 protein is a blue-light photoreceptor from the fungus Botrytis cinerea. This protein has a central role in B. cinerea circadian regulation and is an ortholog to WC-1 from Neurospora crassa. The BcWCL1 and WC-1 proteins have similar protein...

  • Article
  • Open Access
6 Citations
2,633 Views
17 Pages

26 December 2022

The influence of monochromatic green light stimulation on hatching performance and embryo development has been studied in chickens, but not geese. The liver has crucial functions in the regulation of energy metabolism during embryogenesis, but its in...

  • Article
  • Open Access
9 Citations
5,934 Views
18 Pages

A Method to Evaluate the Stimulation of a Real World Field of View by Means of a Spectroradiometric Analysis

  • Fabio Nardecchia,
  • Monica Barbalace,
  • Fabio Bisegna,
  • Chiara Burattini,
  • Franco Gugliermetti,
  • Andrea De Lieto Vollaro,
  • Ferdinando Salata and
  • Iacopo Golasi

10 November 2015

Stimulation elicited by a real world field of view is related to the color, the intensity and the direction of the information reaching the eye: different spectral power distributions of light trigger different responses. An evaluation of the stimula...

  • Editorial
  • Open Access
14 Citations
5,638 Views
5 Pages

16 January 2019

A new piece of equipment for LED (light emitting diode) brain photobiomodulation is introduced. Preliminary results from regional cerebral oxygen saturation and from thermography are shown before, during and after stimulation. The procedure offers a...

  • Article
  • Open Access
3 Citations
2,301 Views
18 Pages

Enhanced Recovery of Food-Grade Euglena gracilis Biomass Through Synergistic pH-Modified Chitosan Flocculation and Green Light Stimulation

  • Jiangyu Zhu,
  • Lan Yang,
  • Li Ding,
  • Zhengfei Yang,
  • Yongqi Yin,
  • Minato Wakisaka,
  • Shahram Ashouri,
  • Mohammadhadi Jazini and
  • Weiming Fang

The efficient and cost-effective harvesting of food-grade Euglena gracilis remains a critical challenge in microalgal food production. This study presents an innovative, food-safe approach integrating pH preconditioning, chitosan biopolymer flocculat...

  • Article
  • Open Access
6 Citations
3,192 Views
25 Pages

23 June 2022

The topological cues of fibrous scaffolds (in particular extracellular matrix (ECM)-mimetic nanofibers) have already proven to be a powerful tool for influencing neuronal morphology and behavior. Remote photothermal optical treatment provides additio...

  • Review
  • Open Access
25 Citations
5,792 Views
44 Pages

12 November 2021

Smart polymer-based micro/nanoassemblies have emerged as a promising alternative for transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) polymeric micro/nanocarrier (PC) strategies may help to conserve cargo activit...

  • Article
  • Open Access
5 Citations
3,170 Views
17 Pages

29 December 2022

A three-dimensional (3D) scaffold ideally provides hierarchical complexity and imitates the chemistry and mechanical properties of the natural cell environment. Here, we report on a stimuli-responsive photo-cross-linkable resin formulation for the fa...

  • Article
  • Open Access
4 Citations
2,648 Views
14 Pages

22 February 2022

Optogenetics is a versatile toolset for the functional investigation of excitable cells such as neurons and cardiomyocytes in vivo and in vitro. While monochromatic illumination of these cells for either stimulation or inhibition already enables a wi...

  • Proceeding Paper
  • Open Access
3 Citations
1,457 Views
14 Pages

Early-Stage Research to Characterize the Electrical Signal of Optically Stimulated Hydroponic Strawberries Using Machine Learning Techniques

  • Levi Garcia-Menchaca,
  • Carlos Guerra-Sánchez,
  • Néji Tarchoun,
  • Raouia Lebbihi,
  • Oscar Cruz-Dominguez,
  • Claudia Sifuentes-Gallardo,
  • Juan Gerardo Peréz-Martínez,
  • Mario Cleva,
  • José Ortega-Sigala and
  • Héctor Durán-Muñoz

Through the electrical signal generated by a plant, it is possible to identify water stress, pests on its roots, a sick plant, or even identify the optimal growing conditions. In particular, the optimal growing conditions in the strawberry plant can...

  • Review
  • Open Access
9 Citations
6,134 Views
14 Pages

Alzheimer’s disease (AD) represents a pressing global health challenge, with an anticipated surge in diagnoses over the next two decades. This progressive neurodegenerative disorder unfolds gradually, with observable symptoms emerging after two...

  • Article
  • Open Access
10 Citations
4,159 Views
12 Pages

Sub-Millisecond Photoinduced Dynamics of Free and EL222-Bound FMN by Stimulated Raman and Visible Absorption Spectroscopies

  • Yingliang Liu,
  • Aditya S. Chaudhari,
  • Aditi Chatterjee,
  • Prokopis C. Andrikopoulos,
  • Alessandra Picchiotti,
  • Mateusz Rebarz,
  • Miroslav Kloz,
  • Victor A. Lorenz-Fonfria,
  • Bohdan Schneider and
  • Gustavo Fuertes

12 January 2023

Time-resolved femtosecond-stimulated Raman spectroscopy (FSRS) provides valuable information on the structural dynamics of biomolecules. However, FSRS has been applied mainly up to the nanoseconds regime and above 700 cm−1, which covers only pa...

  • Article
  • Open Access
3 Citations
3,280 Views
17 Pages

28 June 2019

Liquid crystals (LCs) are organic materials characterized by the intermediate properties between those of an isotropic liquid and a crystal with a long range order. The LCs possess strong anisotropy of their optical and electro-optical properties. In...

  • Article
  • Open Access
1 Citations
1,189 Views
25 Pages

Improved Dual-Modality Bioequivalence Evaluation of Topical Formulations Within Human Skin Using Stimulated Raman Scattering Microscopy

  • Dandan Tu,
  • Nick-Sidney Lemberger,
  • Kristin Wallmeier,
  • Jackson Riseman,
  • Benjamin A. Kuzma,
  • Yuxiao Wei,
  • Ting Chean Khoo,
  • Elena Rantou,
  • Priyanka Ghosh and
  • Conor L. Evans
  • + 3 authors

Background: The use of optical microscopic techniques has gained increasing attention in recent years for studying the bioavailability (BA) and bioequivalence (BE) of topical drugs. Stimulated Raman scattering (SRS), one type of optical imaging techn...

  • Review
  • Open Access
12 Citations
14,302 Views
10 Pages

ACTH Stimulation Test for the Diagnosis of Secondary Adrenal Insufficiency: Light and Shadow

  • Maria Francesca Birtolo,
  • Simone Antonini,
  • Andrea Saladino,
  • Benedetta Zampetti,
  • Elisabetta Lavezzi,
  • Iacopo Chiodini,
  • Gherardo Mazziotti,
  • Andrea G. A. Lania and
  • Renato Cozzi

Secondary Adrenal Insufficiency (SAI) is a condition characterized by inappropriately low ACTH secretion due to a disease or injury to the hypothalamus or the pituitary. The evaluation when suspected is often challenging for the non-specific symptoms...

  • Review
  • Open Access
24 Citations
10,939 Views
46 Pages

Alzheimer’s disease (AD), as a neurodegenerative disorder, usually develops slowly but gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is recognized by WHO as a public health priority. Being a multifactoria...

  • Article
  • Open Access
26 Citations
5,943 Views
14 Pages

28 July 2018

This study is focused on the controllable reduction of the graphene oxide (GO) during the surface-initiated atom transfer radical polymerization technique of glycidyl methacrylate (GMA). The successful modification was confirmed using TGA-FTIR analys...

  • Article
  • Open Access
2 Citations
4,258 Views
11 Pages

Ultrasound Flow Imaging Study on Rat Brain with Ultrasound and Light Stimulations

  • Junhang Zhang,
  • Chen Gong,
  • Zihan Yang,
  • Fan Wei,
  • Xin Sun,
  • Jie Ji,
  • Yushun Zeng,
  • Chi-feng Chang,
  • Xunan Liu and
  • Qifa Zhou
  • + 2 authors

Functional ultrasound (fUS) flow imaging provides a non-invasive method for the in vivo study of cerebral blood flow and neural activity. This study used functional flow imaging to investigate rat brain’s response to ultrasound and colored-ligh...

  • Article
  • Open Access
17 Citations
5,218 Views
9 Pages

Fully Integrated Light-Sensing Stimulator Design for Subretinal Implants

  • Hosung Kang,
  • Wajahat H. Abbasi,
  • Seong-Woo Kim and
  • Jungsuk Kim

28 January 2019

This paper presents a fully integrated photodiode-based low-power and low-mismatch stimulator for a subretinal prosthesis. It is known that a subretinal prosthesis achieves 1600-pixel stimulators on a limited single-chip area that is implanted beneat...

  • Article
  • Open Access
892 Views
14 Pages

All-Light Remote Driving and Programming of Soft Actuator Based on Selective Laser Stimulation and Modification

  • Jingjing Zhang,
  • Hai Hu,
  • Wenliang Liang,
  • Zhijuan Fuyang,
  • Chenchu Zhang and
  • Deng Pan

9 May 2025

Soft robots are advantageous due to their flexibility, ability to interact with humans, and multifunctional adaptability. However, developing soft robots that are unrestrained and can be reprogrammed for reversible control without causing damage rema...

  • Proceeding Paper
  • Open Access
2,551 Views
4 Pages

Temperature-responsive Poly-N-isopropylacrylamide (PNIPAAm) hydrogels were modified with graphene oxide (GO) nanoparticles to increase the light absorption significantly and these gels can be heated and stimulated optothermically. These light-respons...

  • Article
  • Open Access
4 Citations
4,622 Views
8 Pages

2 June 2021

In pigs, it has been reported that increased farrowing rates and litter size have been induced by photostimulating the seminal doses for artificial insemination with red LED light. As the reproductive characteristics, production system, and outcome p...

  • Review
  • Open Access
16 Citations
5,475 Views
13 Pages

Neural Correlates of Delay Discounting in the Light of Brain Imaging and Non-Invasive Brain Stimulation: What We Know and What Is Missed

  • Andrea Stefano Moro,
  • Daniele Saccenti,
  • Mattia Ferro,
  • Simona Scaini,
  • Antonio Malgaroli and
  • Jacopo Lamanna

26 February 2023

In decision making, the subjective value of a reward declines with the delay to its receipt, describing a hyperbolic function. Although this phenomenon, referred to as delay discounting (DD), has been extensively characterized and reported in many an...

  • Article
  • Open Access
8 Citations
4,120 Views
15 Pages

Previous studies have demonstrated that monochromatic light affects plasma melatonin (MEL) levels, which in turn regulates hepatic insulin-like growth factor I (IGF-I) secretion via the Mel1c receptor. However, the intracellular signaling pathway ini...

  • Article
  • Open Access
12 Citations
4,143 Views
13 Pages

In this study, optoelectronic synaptic transistors based on indium–gallium–zinc oxide (IGZO) with a casein electrolyte-based electric double layer (EDL) were examined. The casein electrolyte played a crucial role in modulating synaptic pl...

  • Article
  • Open Access
1 Citations
2,246 Views
9 Pages

26 February 2021

In this study, the effects of a nocturnal light pulse on body weight, organ mass, gonadal function, and plasma levels of metabolites were determined in male mule ducks. In total, 32 15-week-old mule ducks were randomly allocated to either Group C (co...

  • Article
  • Open Access
18 Citations
3,961 Views
21 Pages

18 December 2022

Among all legumes sprouts’ active compounds, isoflavones seem to be the most important; nevertheless, their high content is not always associated with beneficial effects. These compounds may prevent or stimulate hormone-dependent cancers due to...

  • Review
  • Open Access
35 Citations
7,435 Views
29 Pages

26 December 2022

In a random laser (RL), optical feedback arises from multiple scattering instead of conventional mirrors. RLs generate a laser-like emission, and meanwhile take advantage of a simpler and more flexible laser configuration. The applicability of RLs as...

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