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  • Article
  • Open Access
117 Citations
13,192 Views
15 Pages

A Study of Thermal Stability of Hydroxyapatite

  • Natalia V. Bulina,
  • Svetlana V. Makarova,
  • Sergey G. Baev,
  • Alexander A. Matvienko,
  • Konstantin B. Gerasimov,
  • Olga A. Logutenko and
  • Vladimir S. Bystrov

24 November 2021

High-temperature powder sintering is an integral part of the dense ceramic manufacturing process. In order to find the optimal conditions for producing a ceramic product, the information about its behavior at high temperatures is required. However, t...

  • Article
  • Open Access
30 Citations
5,183 Views
14 Pages

Photoluminescent Properties of Hydroxyapatite and Hydroxyapatite/Multi-Walled Carbon Nanotube Composites

  • Edna X. Figueroa-Rosales,
  • Javier Martínez-Juárez,
  • Esmeralda García-Díaz,
  • Daniel Hernández-Cruz,
  • Sergio A. Sabinas-Hernández and
  • Maria J. Robles-Águila

17 July 2021

Hydroxyapatite (HAp) and hydroxyapatite/multi-walled carbon nanotube (MWCNT) composites were obtained by the co-precipitation method, followed by ultrasound-assisted and microwave radiation and thermal treatment at 250 °C. X-ray diffraction (XRD) con...

  • Article
  • Open Access
11 Citations
4,191 Views
17 Pages

Hydroxyapatite and Silicon-Modified Hydroxyapatite as Drug Carriers for 4-Aminopyridine

  • Laura Marincaș,
  • Graziella Liana Turdean,
  • Monica Toșa,
  • Zsolt Kovács,
  • Béla Kovács,
  • Réka Barabás,
  • Noémi-Izabella Farkas and
  • Liliana Bizo

15 September 2021

Adsorption and desorption properties of nano-hydroxyapatite (HAP) and silicon-modified hydroxyapatite (Si–HAP) were investigated with 4-aminopyridine (fampridine-4AP). The novelty of this research is the investigation of the suitability of the previo...

  • Article
  • Open Access
10 Citations
2,652 Views
12 Pages

Influence of the Components and Orientation of Hydroxyapatite Fibrous Substrates on Osteoblast Behavior

  • Shiao-Wen Tsai,
  • Yu-Wei Hsu,
  • Whei-Lin Pan,
  • Adhisankar Vadivelmurugan,
  • Pai-An Hwang and
  • Fu-Yin Hsu

29 September 2022

Synthetic hydroxyapatite has good biocompatibility, bioactivity and osteoconductive ability because its chemical properties and biological properties are similar to those of bioapatite in bone tissue. Strontium-substituted hydroxyapatite has better d...

  • Article
  • Open Access
22 Citations
5,673 Views
12 Pages

Synthesis and Properties of Zinc-Modified Hydroxyapatite

  • Daria Lytkina,
  • Anastasiya Gutsalova,
  • Dmitriy Fedorishin,
  • Natalya Korotchenko,
  • Rafik Akhmedzhanov,
  • Vladimir Kozik and
  • Irina Kurzina

Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue and are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone imp...

  • Article
  • Open Access
49 Citations
5,571 Views
18 Pages

Development of Iron-Doped Hydroxyapatite Coatings

  • Daniela Predoi,
  • Simona Liliana Iconaru,
  • Steluta Carmen Ciobanu,
  • Silviu-Adrian Predoi,
  • Nicolas Buton,
  • Christelle Megier and
  • Mircea Beuran

5 February 2021

It is known that iron is found as a trace element in bone tissue, the main inorganic constituent of which is hydroxyapatite. Therefore, iron-doped hydroxyapatite (HApFe) materials could be new alternatives for many biomedical applications. A facile d...

  • Feature Paper
  • Article
  • Open Access
21 Citations
5,527 Views
18 Pages

Multifunctional Hydroxyapatite Coated with Arthemisia absinthium Composites

  • Mariana Stefania Raita,
  • Simona Liliana Iconaru,
  • Andreea Groza,
  • Carmen Cimpeanu,
  • Gabriel Predoi,
  • Liliana Ghegoiu,
  • Monica Luminita Badea,
  • Mariana Carmen Chifiriuc,
  • Luminita Marutescu and
  • Daniela Predoi
  • + 4 authors

19 January 2020

There is significant research showing that essential oils extracted from the plants have antibacterial effects. The purpose of this study was to develop a biocomposite based on hydroxyapatite coated with Artemisia absinthium essential oil and to high...

  • Article
  • Open Access
3 Citations
3,054 Views
12 Pages

Intrafibrillar Growth of Hydroxyapatite Nanocrystals in Multiscale Collagen

  • Bingyu Xue,
  • Yidi Li,
  • Zhengyi Fu,
  • Hang Ping and
  • Kun Wang

18 April 2023

Collagen fibrils hierarchically assemble from microscale to macroscale, which endows the natural composite bone with good mechanical properties and remodeling functions. Revealing the intrafibrillar growth process of hydroxyapatite nanocrystals of co...

  • Article
  • Open Access
6 Citations
2,547 Views
13 Pages

Characterization and Evaluation of Silver Concentrations in Hydroxyapatite Powders

  • Néstor Méndez-Lozano,
  • Miguel Apatiga-Castro,
  • Alvaro de Jesús Ruíz-Baltazar,
  • Miguel de la Luz-Asunción and
  • Eduardo E. Pérez-Ramírez

11 September 2023

The goal of this study is to evaluate the influence of the concentration of silver on the structural and antimicrobial in vitro properties of silver-doped hydroxyapatite powders obtained using the precipitation method. Different concentrations of sil...

  • Article
  • Open Access
7 Citations
1,722 Views
16 Pages

Influence of Polymeric Blends on Bioceramics of Hydroxyapatite

  • Eduardo da Silva Gomes,
  • Antônia Millena de Oliveira Lima,
  • Sílvia Rodrigues Gavinho,
  • Manuel Pedro Fernandes Graça,
  • Susana Devesa and
  • Ana Angélica Mathias Macêdo

26 September 2023

Bioceramics are used to repair, rebuild, and replace parts of the human body, e.g., bones, joints and teeth, in the form of powder, coatings or prostheses. The synthetic hydroxyapatite [Ca10(PO4)6(OH)2 (HAP)] based on calcium phosphate has been widel...

  • Article
  • Open Access
1 Citations
1,610 Views
14 Pages

Rheological Behavior of Ion-Doped Hydroxyapatite Slurries

  • Zahid Abbas,
  • Massimiliano Dapporto,
  • Andreana Piancastelli,
  • Davide Gardini,
  • Anna Tampieri and
  • Simone Sprio

The present work investigates the rheological behavior of ceramic slurries made of hydroxyapatite powders doped with magnesium and strontium ions and selected as particularly relevant for biomedical applications. The incorporation of doping ions into...

  • Article
  • Open Access
9 Citations
2,983 Views
9 Pages

Uniaxial Hydroxyapatite Growth on a Self-Assembled Protein Scaffold

  • Alexander L. Danesi,
  • Dimitra Athanasiadou,
  • Ahmad Mansouri,
  • Alina Phen,
  • Mehrnoosh Neshatian,
  • James Holcroft,
  • Johan Bonde,
  • Bernhard Ganss and
  • Karina M. M. Carneiro

15 November 2021

Biomineralization is a crucial process whereby organisms produce mineralized tissues such as teeth for mastication, bones for support, and shells for protection. Mineralized tissues are composed of hierarchically organized hydroxyapatite crystals, wi...

  • Article
  • Open Access
617 Views
14 Pages

Elaboration of Natural Hydroxyapatite Coating by Plasma Spraying

  • Maya Kebaili,
  • Amina Ghedjemis,
  • Lilia Benchikh,
  • Yazid Aitferhat,
  • Ilyes Abacha,
  • Kamel Hebbache,
  • Cherif Belebchouche and
  • El Hadj Kadri

17 December 2025

Metallic implants used in orthopedics, such as titanium alloys, possess excellent mechanical strength but suffer from corrosion and poor bio-integration, often necessitating revision surgeries. Bioactive coatings, particularly hydroxyapatite, can enh...

  • Article
  • Open Access
10 Citations
3,037 Views
13 Pages

Synthesis and Biological Properties of Alanine-Grafted Hydroxyapatite Nanoparticles

  • Bruna Carolina Dorm,
  • Mônica Rosas Costa Iemma,
  • Benedito Domingos Neto,
  • Rauany Cristina Lopes Francisco,
  • Ivana Dinić,
  • Nenad Ignjatović,
  • Smilja Marković,
  • Marina Vuković,
  • Srečo Škapin and
  • Lidija Mančić
  • + 1 author

31 December 2022

Hydroxyapatite attracts great attention as hard tissues implant material for bones and teeth. Its application in reconstructive medicine depends on its biocompatibility, which is in a function of composition and surface properties. The insertion of a...

  • Review
  • Open Access
42 Citations
9,014 Views
16 Pages

Biomimetic Action of Zinc Hydroxyapatite on Remineralization of Enamel and Dentin: A Review

  • Andrea Butera,
  • Carolina Maiorani,
  • Simone Gallo,
  • Maurizio Pascadopoli,
  • Martina Quintini,
  • Marco Lelli,
  • Fabrizio Tarterini,
  • Ismaela Foltran and
  • Andrea Scribante

Biomimetic zinc–carbonate hydroxyapatite technology was developed to realize materials that mimic the natural hydroxyapatite of enamel and dentin and possess good activity in terms of affinity to adhere to these biological tissues. The chemical...

  • Review
  • Open Access
194 Citations
10,928 Views
24 Pages

Hydroxyapatite Nanoparticles in Drug Delivery: Physicochemistry and Applications

  • Sofía Lara-Ochoa,
  • Wendy Ortega-Lara and
  • Carlos Enrique Guerrero-Beltrán

Hydroxyapatite (HAP) has been the gold standard in the biomedical field due to its composition and similarity to human bone. Properties such as shape, size, morphology, and ionic substitution can be tailored through the use of different synthesis tec...

  • Review
  • Open Access
94 Citations
19,710 Views
19 Pages

Dental Applications of Systems Based on Hydroxyapatite Nanoparticles—An Evidence-Based Update

  • Silvia Balhuc,
  • Radu Campian,
  • Anca Labunet,
  • Marius Negucioiu,
  • Smaranda Buduru and
  • Andreea Kui

11 June 2021

Hydroxyapatite is one of the most studied biomaterials in the medical and dental field, because of its biocompatibility; it is the main constituent of the mineral part of teeth and bones. In dental science, hydroxyapatite nanoparticles (HAnps) or nan...

  • Article
  • Open Access
42 Citations
5,062 Views
19 Pages

Hydroxyapatite from Natural Sources for Medical Applications

  • Laura Madalina Cursaru,
  • Miruna Iota,
  • Roxana Mioara Piticescu,
  • Daniela Tarnita,
  • Sorin Vasile Savu,
  • Ionel Dănuț Savu,
  • Gabriela Dumitrescu,
  • Diana Popescu,
  • Radu-Gabriel Hertzog and
  • Mihaela Calin

22 July 2022

The aim of this work is to study the physical-chemical, mechanical, and biocompatible properties of hydroxyapatite obtained by hydrothermal synthesis, at relatively low temperatures and high pressures, starting from natural sources (Rapana whelk shel...

  • Article
  • Open Access
21 Citations
4,835 Views
16 Pages

Establishment of Collagen: Hydroxyapatite/BMP-2 Mimetic Peptide Composites

  • Liane Schuster,
  • Nina Ardjomandi,
  • Marita Munz,
  • Felix Umrath,
  • Christian Klein,
  • Frank Rupp,
  • Siegmar Reinert and
  • Dorothea Alexander

7 March 2020

Extensive efforts were undertaken to develop suitable biomaterials for tissue engineering (TE) applications. To facilitate clinical approval processes and ensure the success of TE applications, bioinspired concepts are currently focused on. Working o...

  • Review
  • Open Access
54 Citations
7,761 Views
22 Pages

Advanced Materials Based on Nanosized Hydroxyapatite

  • Ramón Rial,
  • Michael González-Durruthy,
  • Zhen Liu and
  • Juan M. Ruso

The development of new materials based on hydroxyapatite has undergone a great evolution in recent decades due to technological advances and development of computational techniques. The focus of this review is the various attempts to improve new hydr...

  • Article
  • Open Access
13 Citations
3,094 Views
17 Pages

Inhibitory Effect of Adsorption of Streptococcus mutans onto Scallop-Derived Hydroxyapatite

  • Momoko Usuda,
  • Mariko Kametani,
  • Masakazu Hamada,
  • Yuto Suehiro,
  • Saaya Matayoshi,
  • Rena Okawa,
  • Shuhei Naka,
  • Michiyo Matsumoto-Nakano,
  • Tatsuya Akitomo and
  • Ryota Nomura
  • + 9 authors

Hydroxyapatite adsorbs various substances, but little is known about the effects on oral bacteria of adsorption onto hydroxyapatite derived from scallop shells. In the present study, we analyzed the effects of adsorption of Streptococcus mutans onto...

  • Article
  • Open Access
22 Citations
3,931 Views
11 Pages

Preparation and Properties of Double-Crosslinked Hydroxyapatite Composite Hydrogels

  • Benbo Zhao,
  • Mingda Zhao,
  • Liming Li,
  • Shixiong Sun,
  • Heping Yu,
  • Yuan Cheng,
  • Yuedi Yang,
  • Yujiang Fan and
  • Yong Sun

1 September 2022

Natural polymer hydrogels have good mechanical properties and biocompatibility. This study designed hydroxyapatite-enhanced photo-oxidized double-crosslinked hydrogels. Hyaluronic acid (HA) and gelatin (Gel) were modified with methacrylate anhydride....

  • Review
  • Open Access
234 Citations
17,119 Views
42 Pages

Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review

  • Mythili Prakasam,
  • Janis Locs,
  • Kristine Salma-Ancane,
  • Dagnija Loca,
  • Alain Largeteau and
  • Liga Berzina-Cimdina

21 December 2015

In the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applic...

  • Article
  • Open Access
12 Citations
2,849 Views
15 Pages

An Evaluation of the Mechanical Properties of a Hybrid Composite Containing Hydroxyapatite

  • Leszek Klimek,
  • Karolina Kopacz,
  • Beata Śmielak and
  • Zofia Kula

23 June 2023

There is currently a lack of scientific reports on the use of composites based on UDMA resin containing HAp in conservative dentistry. The aim of this study was therefore to determine the effect of hydroxyapatite content on the properties of a hybrid...

  • Article
  • Open Access
13 Citations
3,759 Views
17 Pages

Incorporation of Chloramphenicol Loaded Hydroxyapatite Nanoparticles into Polylactide

  • Manuel Rivas,
  • Marc Pelechà,
  • Lourdes Franco,
  • Pau Turon,
  • Carlos Alemán,
  • Luis J. del Valle and
  • Jordi Puiggalí

11 October 2019

Chloramphenicol (CAM) has been encapsulated into hydroxyapatite nanoparticles displaying different morphologies and crystallinities. The process was based on typical precipitation of solutions containing phosphate and calcium ions and the addition of...

  • Review
  • Open Access
147 Citations
10,778 Views
21 Pages

Luminescent Hydroxyapatite Doped with Rare Earth Elements for Biomedical Applications

  • Ionela Andreea Neacsu,
  • Alexandra Elena Stoica,
  • Bogdan Stefan Vasile and
  • Ecaterina Andronescu

10 February 2019

One new, promising approach in the medical field is represented by hydroxyapatite doped with luminescent materials for biomedical luminescence imaging. The use of hydroxyapatite-based luminescent materials is an interesting area of research because o...

  • Article
  • Open Access
7 Citations
3,192 Views
15 Pages

Hydroxyapatite is known to have excellent catalytic properties for ethanol conversion and lactic acid conversion, and their properties are influenced by the elemental composition, such as Ca/P ratio and sodium content. However, few reports have been...

  • Review
  • Open Access
50 Citations
7,033 Views
23 Pages

Recent Trends in Hydroxyapatite Supplementation for Osteoregenerative Purposes

  • Ana Zastulka,
  • Simona Clichici,
  • Maria Tomoaia-Cotisel,
  • Aurora Mocanu,
  • Cecilia Roman,
  • Cristian-Doru Olteanu,
  • Bogdan Culic and
  • Teodora Mocan

3 February 2023

Bone regeneration has gained attention in the biomedical field, which has led to the development of materials and synthesis methods meant to improve osseointegration and cellular bone activity. The properties of hydroxyapatite, a type of calcium phos...

  • Article
  • Open Access
14 Citations
2,524 Views
15 Pages

Diffusion of Copper Ions in the Lattice of Substituted Hydroxyapatite during Heat Treatment

  • Natalia V. Bulina,
  • Natalya V. Eremina,
  • Olga B. Vinokurova,
  • Arcady V. Ishchenko and
  • Marina V. Chaikina

20 August 2022

The doping of hydroxyapatite with various substituent ions can give this material new and useful properties. Nonetheless, local distortions of structure after doping can change the properties of the material. In this work, the thermal stability of co...

  • Extended Abstract
  • Open Access
1 Citations
1,357 Views
2 Pages

Carbonated Hydroxyapatite Substituted with Magnesium for Stone Consolidation

  • Lorena Iancu,
  • Rodica-Mariana Ion,
  • Ramona Marina Grigorescu,
  • Paul Niculae Ghioca,
  • Bogdan Spurcaciu,
  • Madalina Elena David,
  • Ramona Elena Andrei,
  • Marius Ghiurea,
  • Raluca Maria Stirbescu and
  • Alin Bucurica

Carbonated hydroxyapatite (CHAp) is an inorganic compound with various applications that presents better homogeneity and consolidating effect than HAp [1]. [...]

  • Article
  • Open Access
55 Citations
7,880 Views
17 Pages

Properties of Basil and Lavender Essential Oils Adsorbed on the Surface of Hydroxyapatite

  • Daniela Predoi,
  • Andreea Groza,
  • Simona Liliana Iconaru,
  • Gabriel Predoi,
  • Florica Barbuceanu,
  • Regis Guegan,
  • Mikael Stefan Motelica-Heino and
  • Carmen Cimpeanu

24 April 2018

The research conducted in this study presented for the first time results of physico-chemical properties and in vitro antimicrobial activity of hydroxyapatite plant essential oil against Gram-positive bacteria (methicillin-resistant Staphylococcus au...

  • Article
  • Open Access
4 Citations
8,229 Views
14 Pages

Real-Time Protein and Cell Binding Measurements on Hydroxyapatite Coatings

  • A. M. Vilardell,
  • N. Cinca,
  • A. Jokinen,
  • N. Garcia-Giralt,
  • S. Dosta,
  • I. G. Cano and
  • J. M. Guilemany

Although a lot of in vitro and in vivo assays have been performed during the last few decades years for hydroxyapatite bioactive coatings, there is a lack of exploitation of real-time in vitro interaction measurements. In the present work, real-time...

  • Article
  • Open Access
13 Citations
4,329 Views
18 Pages

Preparation, Characterization, and Biological Properties of Hydroxyapatite from Bigeye Snapper (Priancanthus tayenus) Bone

  • Nunnuth Jindapon,
  • Phatthranit Klinmalai,
  • Utoomporn Surayot,
  • Nuttapol Tanadchangsaeng,
  • Woradej Pichaiaukrit,
  • Yuthana Phimolsiripol,
  • Chaluntorn Vichasilp and
  • Sutee Wangtueai

1 February 2023

The optimum condition of acid hydrolysis for hydroxyapatite extraction from bigeye snapper (Priancanthus tayenus) bone and the effects of extraction time (10–60 min) and HCl concentration (2.0–5.0% w/v) on yield and hydroxyapatite propert...

  • Article
  • Open Access
29 Citations
5,446 Views
12 Pages

9 November 2018

Hydroxyapatite crystallization for phosphorus recovery and removal from wastewater has attracted considerable attention for its potential economic and environmental benefits because hydroxyapatite can used as an effective compound fertilizer containi...

  • Article
  • Open Access
12 Citations
6,364 Views
13 Pages

Synthesis of Graphene Nanoribbons–Hydroxyapatite Nanocomposite Applicable in Biomedicine and Theranostics

  • Hassan Nosrati,
  • Rasoul Sarraf-Mamoory,
  • Amir Hossein Ahmadi and
  • Maria Canillas Perez

In order to investigate the effect of graphene nanoribbons on the final properties of hydroxyapatite-based nanocomposites, a solvothermal method was used at 180 °C and 5 h for the synthesis of graphene nanoribbons–hydroxyapatite nanopowders...

  • Article
  • Open Access
2 Citations
2,026 Views
20 Pages

Electrophoretic Deposition of Chitosan–Hydroxyapatite Films and Their Electrochemical Behavior in Artificial Plasma

  • J. P. Mata-Davila,
  • C. D. Arrieta-Gonzalez,
  • F. J. Perez-Arizmendi,
  • M. A. Dorta-Leon,
  • F. Brown-Bojorquez and
  • J. Porcayo-Calderon

30 October 2023

The electrochemical behavior of chitosan–hydroxyapatite films deposited on Ti CP was evaluated. Hydroxyapatite was synthesized from eggshell at different precipitation pH conditions. The films were deposited on the Ti CP surface from chitosan&n...

  • Review
  • Open Access
32 Citations
5,282 Views
14 Pages

Hydroxyapatite Use in Spine Surgery—Molecular and Clinical Aspect

  • Jakub Litak,
  • Wojciech Czyzewski,
  • Michał Szymoniuk,
  • Bartlomiej Pastuszak,
  • Joanna Litak,
  • Grzegorz Litak,
  • Cezary Grochowski,
  • Mansur Rahnama-Hezavah and
  • Piotr Kamieniak

15 April 2022

Hydroxyapatite possesses desirable properties as a scaffold in tissue engineering: it is biocompatible at a site of implantation, and it is degradable to non-toxic products. Moreover, its porosity enables infiltration of cells, nutrients and waste pr...

  • Proceeding Paper
  • Open Access
1,158 Views
4 Pages

Research of the Influence of Zinc Ions on Synthesis and Properties of Hydroxyapatite

  • Dmitriy Fedorishin,
  • Anastasiya Gutsalova,
  • Daria Lytkina and
  • Irina Kurzina

9 November 2020

Hydroxyapatites modified with metal ions are the main inorganic components of bone tissue that are approved for use as components for biocomposites and coatings for surgical implants. This study examined prototypes of functional materials for bone im...

  • Article
  • Open Access
8 Citations
2,725 Views
9 Pages

Surface Structure and Properties of Hydroxyapatite Coatings on NiTi Substrates

  • Ekaterina S. Marchenko,
  • Kirill M. Dubovikov,
  • Gulsharat A. Baigonakova,
  • Ivan I. Gordienko and
  • Alex A. Volinsky

31 March 2023

Hydroxyapatite coatings were deposited for 1, 2, and 3 h on NiTi substrates using plasma-assisted radio frequency sputtering. The matrix consisted of NiTi B2 and NiTi B19’ phases and Ti2Ni, Ni3Ti, and Ni4Ti3 intermetallic compounds. The surface...

  • Article
  • Open Access
11 Citations
4,033 Views
19 Pages

Hydroxyapatite-Coated SPIONs and Their Influence on Cytokine Release

  • Bernhard Friedrich,
  • Jean-Philippe Auger,
  • Silvio Dutz,
  • Iwona Cicha,
  • Eveline Schreiber,
  • Julia Band,
  • Aldo R. Boccacccini,
  • Gerhard Krönke,
  • Christoph Alexiou and
  • Rainer Tietze

Hydroxyapatite- or calcium phosphate-coated iron oxide nanoparticles have a high potential for use in many biomedical applications. In this study, a co-precipitation method for the synthesis of hydroxyapatite-coated nanoparticles (SPIONHAp), was used...

  • Article
  • Open Access
128 Citations
7,321 Views
13 Pages

Synthesis and Characterization of PLA-Micro-structured Hydroxyapatite Composite Films

  • Andreea Madalina Pandele,
  • Andreea Constantinescu,
  • Ionut Cristian Radu,
  • Florin Miculescu,
  • Stefan Ioan Voicu and
  • Lucian Toma Ciocan

8 January 2020

This article presents a facile synthesis method used to obtain new composite films based on polylactic acid and micro-structured hydroxyapatite particles. The composite films were synthesized starting from a polymeric solution in chloroform (12 wt.%)...

  • Article
  • Open Access
10 Citations
3,464 Views
15 Pages

Structural and Chemical Hierarchy in Hydroxyapatite Coatings

  • Karlis A. Gross,
  • Christiane Petzold,
  • Liene Pluduma-LaFarge,
  • Maris Kumermanis and
  • Håvard J. Haugen

7 October 2020

Hydroxyapatite coatings need similarly shaped splats as building blocks and then a homogeneous microstructure to unravel the structural and chemical hierarchy for more refined improvements to implant surfaces. Coatings were thermally sprayed with dif...

  • Article
  • Open Access
3 Citations
2,478 Views
17 Pages

Bioactive Hydroxyapatite Aerogels with Piezoelectric Particles

  • Catarina Tavares,
  • Tânia Vieira,
  • Jorge C. Silva,
  • João P. M. R. Borges and
  • M. Carmo Lança

Open-cell foams based on hydroxyapatite (HAp) can mimic the extracellular matrix (ECM) to better replace damaged hard tissues and assist in their regeneration processes. Aerogels of HAp nanowires (NW) with barium titanate (BT) particles were produced...

  • Article
  • Open Access
54 Citations
5,857 Views
16 Pages

Biomimetic Synthesis of Nanocrystalline Hydroxyapatite Composites: Therapeutic Potential and Effects on Bone Regeneration

  • Chih-Hsiang Fang,
  • Yi-Wen Lin,
  • Feng-Huei Lin,
  • Jui-Sheng Sun,
  • Yuan-Hung Chao,
  • Hung-Ying Lin and
  • Zwei-Chieng Chang

28 November 2019

The development of a novel alloplastic graft with both osteoinductive and osteoconductive properties is still necessary. In this study, we tried to synthesize a biomimetic hydroxyapatite microspheres (gelatin/nano-hydroxyapatite microsphere embedded...

  • Communication
  • Open Access
3 Citations
2,009 Views
8 Pages

Microwave-Assisted Hydrothermal Synthesis of Hydroxyapatite Flakes as Substrates for Titanium Dioxide Film Deposition

  • Néstor Méndez-Lozano,
  • Eduardo E. Pérez-Ramírez and
  • Miguel de la Luz-Asunción

28 May 2024

This article describes the synthesis of hydroxyapatite (HAp) flakes through a microwave-assisted hydrothermal method. These flakes suggest possible applications as a substrate for depositing titanium dioxide (TiO2) films using chemical vapor depositi...

  • Article
  • Open Access
26 Citations
3,732 Views
19 Pages

Iron in Hydroxyapatite: Interstitial or Substitution Sites?

  • Leon Avakyan,
  • Ekaterina Paramonova,
  • Vladimir Bystrov,
  • José Coutinho,
  • Sandrine Gomes and
  • Guillaume Renaudin

5 November 2021

Iron-doped hydroxyapatite (Fe-HAp) is regarded as a promising magnetic material with innate biocompatibility. Despite the many studies reported in the literature, a detailed theoretical description of Fe inclusions is still missing. There is even no...

  • Review
  • Open Access
9 Citations
6,121 Views
11 Pages

Overview on Adjunct Ingredients Used in Hydroxyapatite-Based Oral Care Products

  • Joachim Enax,
  • Bennett T. Amaechi,
  • Erik Schulze zur Wiesche and
  • Frederic Meyer

Hydroxyapatite, Ca5(PO4)3(OH), is a biomimetic active ingredient, which is used in commercial oral care products such as toothpastes and mouthwashes worldwide. Clinical studies (in vivo) as well as in situ and in vitro studies have shown the preventi...

  • Article
  • Open Access
5 Citations
1,907 Views
17 Pages

Synthesis of Hydroxyapatite-Gelatin Composite Hydrogel for Bone Tissue Application

  • José Luis Barrera Bernal,
  • Íñigo Gaytán Salvatella,
  • Bryan Iván Martín del Campo,
  • Marco Antonio Alvarez Perez and
  • David Masuoka-Ito

10 August 2025

Bone tissue engineering has gained attention recently as a method for regenerating bone critical-size defects. This work aims to synthesize a hydrogel based on gelatin, di-amine polyethylene glycol, Polyethylene Glycol-Polypropylene Glycol-Polyethyle...

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