42 Results Found

Moore’s law states that the performance of computers doubles about every two years. This has dramatic consequences for any modern high development and for satellites. The long development cycles cause these expensive assets to be obsolete befor...

Atmospheric aerosols represent an important component of the Earth’s climate system because they can contribute both positive and negative forcing to the energy budget. We are developing the Aerosol Radiometer for Global Observations of the Str...

In the present work, sedimentary microbial fuel cells (s-MFC) have been proposed as effective tools to power remote sensors in different aquatic environments, thanks to their ability to produce renewable and sustainable energy continuously and autono...

Membrane chromatography is routinely used to remove host cell proteins, viral particles, and aggregates during antibody downstream processing. The application of membrane chromatography to the field of antibody-drug conjugates (ADCs) has been applied...

Space exploration presents vast prospects for scientific, industrial, and economic progress. This paper introduces the MeSat mission as a pioneering approach to Mars exploration. The MeSat aims to deepen our understanding of Martian conditions and re...

Investigations about the feasibility of delivery systems with unmanned aerial vehicles (UAVs) or drones have been recently expanded, owing to the exponential demand for goods to be delivered in the recent years, which has been further increased by th...

Robot manipulators possess the capability to autonomously execute complex sequences of actions. Their proficiency in handling challenging and hazardous tasks has led to their widespread adoption across diverse sectors, including industry, business, h...

We propose a novel data hiding method in an audio host with a compressive sampling technique. An over-complete dictionary represents a group of watermarks. Each row of the dictionary is a Hadamard sequence representing multiple bits of the watermark....

At present, most small satellites are delivered as hosted payloads on large launch vehicles. Considering the current technological development, constellations of small satellites can provide a broad range of services operating at designated orbits. T...

The darknet (i.e., a set of unused IP addresses) is a very useful solution for observing the global trends of cyber threats and analyzing attack activities on the Internet. Since the darknet is not connected with real systems, in most cases, the inco...

Protein-shelled viruses have been thought as “tin cans” that merely carry the genomic cargo from cell to cell. However, through the years, it has become clear that viruses such as rhinoviruses and caliciviruses are active and dynamic stru...

With the advent of microservice-based software architectures, an increasing number of modern cloud environments and enterprises use operating system level virtualization, which is often referred to as container infrastructures. Docker Swarm is one of...

The Stratospheric Aerosol and Gas Experiment III (SAGE III) on the International Space Station (ISS) is widely accepted as a stable source for high-quality stratospheric ozone, aerosol, and water vapor measurements since it was installed on the ISS i...

Foot-and-mouth disease (FMD) remains one of the major threats to animal health worldwide. Its causative agent, the FMD virus (FMDV), affects cloven-hoofed animals, including farm animals and wildlife species, inflicting severe damage to the internati...

In this work, a reversible watermarking technique is proposed for DICOM (Digital Imaging and Communications in Medicine) image that offers high embedding capacity (payload), security and fidelity of the watermarked image. The goal is achieved by embe...

Reversible data hiding (RDH) has become a hot spot in recent years as it allows both the secret data and the raw host to be perfectly reconstructed, which is quite desirable in sensitive applications requiring no degradation of the host. A lot of RDH...

Most modern Earth and Universe observation spacecraft are now equipped with large lightweight and flexible structures, such as antennas, telescopes, and extendable elements. The trend of hosting more complex and bigger appendages, essential for high-...

Sustainability and resource optimization have spurred interest in giving a second life to used equipment, often discarded after limited use. Within this framework, we conducted a multidisciplinary, final-year engineering project to explore the revers...

The cultivation of cyanobacteria by exploiting available in situ resources represents a possible way to supply food and oxygen to astronauts during long-term crewed missions on Mars. Here, we evaluated the possibility of cultivating the extremophile...

Precise delivery of therapeutics to the target structures is essential for treatment efficiency and safety. Drug administration via conventional routes requires overcoming multiple transport barriers to achieve and maintain the local drug concentrati...

Carbon nanotubes (CNTs), owing to their high surface area-to-volume ratio and hollow core, can be employed as hosts for adsorbed and/or encapsulated molecules. At high temperatures, the ends of CNTs close spontaneously, which is relevant for several...

Metal-organic framework nanoparticles (MOF NPs) are promising guest-host materials with applications in separation, storage, catalysis, and drug delivery. However, on- and off-loading of guest molecules by porous MOF nanostructures are still poorly u...

Oncolytic virotherapy for cancer is an innovative therapeutic option where the ability of a virus to promote cell lysis is harnessed and reprogrammed to selectively destroy cancer cells. Such treatment modalities exhibited antitumor activity in precl...

Medical imaging is an active field of research that fosters the necessity for novel multimodal imaging probes. In this line, nanoparticle-based contrast agents are of special interest, since those can host functional entities either within their inte...

We report on the efficacy of the non-attenuated HER2-retargeted oHSV named R-337 against the immunologically hot CT26-HER2 tumor, and an insight into the basis of the immune protection. Preliminarily, we conducted an RNA immune profiling and immune c...

NUSES is a planned space mission aiming to test new observational and technological approaches related to the study of relatively low-energy cosmic rays, gamma rays, and high-energy astrophysical neutrinos. Two scientific payloads will be hosted onbo...

NUSES is a planned space mission aiming to test new observational and technological approaches related to the study of low-energy cosmic rays, gamma rays, and high-energy astrophysical neutrinos. Two scientific payloads will be hosted onboard the NUS...

Pancreatic cancer presents formidable challenges due to rapid progression and resistance to conventional treatments. Oncolytic viruses (OVs) selectively infect cancer cells and cause cancer cells to lyse, releasing molecules that can be identified by...

In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and transporting the mRNA payload into host cells. Despite their prominenc...

Cyclodextrins can serve as carriers for various payloads, utilizing their capacity to form unique host–guest inclusion complexes within their cavity and their versatile surface functionalization. Recently, cationic cyclodextrins have gained con...

Recent advancements in the field of in vitro transcribed mRNA (IVT-mRNA) vaccination have attracted considerable attention to such vaccination as a cutting-edge technique against infectious diseases including COVID-19 caused by SARS-CoV-2. While nume...

As key effector cells of the innate immune response, neutrophils are rapidly deployed to sites of inflammation where they deliver a payload of potent effector mechanisms that are essential for host defense against pathogens as well as tissue homeosta...

Lactic acid bacteria (LAB) are central to food, feed, and health biotechnology, yet their genomes have long resisted rapid, precise manipulation. This review charts the evolution of LAB genome-editing strategies from labor-intensive RecA-dependent do...

We designed a Network Exfiltration Detection System (NEDS) to detect data exfiltration as occurring in ransomware attacks. The NEDS operates on aggregated metadata, which is more privacy-friendly and allows analysis of large volumes of high-speed net...

Bacteriophages (phages), the most abundant biological entities on Earth, have long served as both model systems and therapeutic tools. Recent advances in synthetic biology and genetic engineering have revolutionized the capacity to tailor phages with...

Inhibition of AB5-type bacterial toxins can be achieved by heterobifunctional ligands (BAITs) that mediate assembly of supramolecular complexes involving the toxin’s pentameric cell membrane-binding subunit and an endogenous protein, serum amyloid P...

Liposomes started to be studied for drug delivery in 1970s, taking advantage of their ability to encapsulate hydrophilic and hydrophobic drugs using biodegradable and biocompatible molecules. Nowadays, they remain one of the most promising strategies...

An intrusion detection system (IDS) plays a critical role in maintaining network security by continuously monitoring network traffic and host systems to detect any potential security breaches or suspicious activities. With the recent surge in cyberat...

Recent advances have shown for the first time that it is possible to beat a human with an autonomous drone in a drone race. However, this solution relies heavily on external sensors, specifically on the use of a motion capture system. Thus, a truly a...

The lunar lava tubes are envisioned as possible hosting structures for a human base in the Moon’s equatorial regions, providing shelter from radiations, micrometeoroids, and temperature excursion. A first robotic mission is set to scout the hab...

The remotely operated vehicle (ROV), a vital deep-sea platform, offers key advantages, including operational duration via continuous umbilical power, high task adaptability, and zero human risk. It has become indispensable for deep-sea scientific res...

The Harmony satellite mission was recently approved as the next European Space Agency (ESA) Earth Explorer 10. The mission science objectives cover several applications related to solid earth, the cryosphere, upper-ocean dynamics and air–sea in...