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471 Results Found

  • Review
  • Open Access
20 Citations
3,952 Views
21 Pages

Three-dimensional printing (3DP) technology in pharmaceutical areas is leading to a significant change in controlled drug delivery and pharmaceutical product development. Pharmaceutical industries and academics are becoming increasingly interested in...

  • Article
  • Open Access
4 Citations
3,340 Views
19 Pages

Development of CNT-Based Nanocomposites with Ohmic Heating Capability towards Self-Healing Applications in Extrusion-Based 3D Printing Technologies

  • Niki Loura,
  • Eleni Gkartzou,
  • Aikaterini-Flora Trompeta,
  • Georgios Konstantopoulos,
  • Panagiotis A. Klonos,
  • Apostolos Kyritsis and
  • Costas A. Charitidis

17 November 2023

In the present study, a series of carbon-based nanocomposites based on recycled thermoplastic polyurethane (TPU) matrix and MWCNT fillers synthesized in a laboratory environment were prepared at various loadings and assessed in terms of their functio...

  • Feature Paper
  • Review
  • Open Access
28 Citations
7,812 Views
30 Pages

30 January 2024

Three-dimensional printed electrodes seem to overcome many structural and operational limitations compared to ones fabricated with conventional methods. Compared to other 3D printing techniques, direct ink writing (DIW), as a sub-category of extrusio...

  • Article
  • Open Access
22 Citations
5,564 Views
15 Pages

Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies

  • Felix Ditzinger,
  • Daniel J. Price,
  • Anita Nair,
  • Johanna Becker-Baldus,
  • Clemens Glaubitz,
  • Jennifer B. Dressman,
  • Christoph Saal and
  • Martin Kuentz

Amorphous formulation technologies to improve oral absorption of poorly soluble active pharmaceutical ingredients (APIs) have become increasingly prevalent. Currently, polymer-based amorphous formulations manufactured by spray drying, hot melt extrus...

  • Article
  • Open Access
2 Citations
1,830 Views
19 Pages

Effects of Cassava and Modified Starch on the Structural and Functional Characteristics of Peanut Protein-Based Meat Analogs

  • Yuhan Su,
  • Jiale Guan,
  • Shuhong Liu,
  • Yiqun Zhu,
  • Liangyan Hu,
  • Yifan Zhang,
  • Fei Lu and
  • Minpeng Zhu

17 August 2025

Meat analog manufacturing via high-moisture extrusion technology is a complex process wherein the properties of protein materials constitute a critical determining factor. In this study, we enhanced the fiber structure properties of high-moisture ext...

  • Article
  • Open Access
2,049 Views
15 Pages

The Formulation and Evaluation of Customized Prednisolone Gel Tablets Prepared by an Automated Extrusion-Based Material Deposition Method

  • Marina Tihhonova,
  • Andres Meos,
  • Sari Airaksinen,
  • Jaan Aruväli,
  • Niklas Sandler Topelius,
  • Jyrki Heinämäki and
  • Urve Paaver

Background/Objectives: An automated extrusion-based material deposition is a contemporary and rapid method for pharmaceutical dose-dispensing and preparing (printing) individualized solid dosage forms. The aim of this study was to investigate and gai...

  • Feature Paper
  • Article
  • Open Access
136 Citations
12,537 Views
11 Pages

A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks

  • Ratima Suntornnond,
  • Edgar Yong Sheng Tan,
  • Jia An and
  • Chee Kai Chua

6 September 2016

Pneumatic extrusion-based bioprinting is a recent and interesting technology that is very useful for biomedical applications. However, many process parameters in the bioprinter need to be fully understood in order to print at an adequate resolution....

  • Review
  • Open Access
312 Citations
20,519 Views
34 Pages

Polymers for Extrusion-Based 3D Printing of Pharmaceuticals: A Holistic Materials–Process Perspective

  • Mohammad A. Azad,
  • Deborah Olawuni,
  • Georgia Kimbell,
  • Abu Zayed Md Badruddoza,
  • Md. Shahadat Hossain and
  • Tasnim Sultana

Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome the traditional manufacturing regime of 'one size fits for all'. Using 3D printing, it is possible to...

  • Article
  • Open Access
52 Citations
11,323 Views
22 Pages

Extrusion-Based 3D Printing of Ceramic Pastes: Mathematical Modeling and In Situ Shaping Retention Approach

  • Fuwen Hu,
  • Tadeusz Mikolajczyk,
  • Danil Yurievich Pimenov and
  • Munish Kumar Gupta

28 February 2021

Extrusion-based three-dimensional (3D) printing methods are preferred and emerging approaches for freely digital fabrication of ceramics due to ease of use, low investment, high utilization of materials, and good adaptability to multi-materials. Howe...

  • Review
  • Open Access
86 Citations
9,617 Views
63 Pages

Additive Manufacturing Strategies for Personalized Drug Delivery Systems and Medical Devices: Fused Filament Fabrication and Semi Solid Extrusion

  • Giulia Auriemma,
  • Carmela Tommasino,
  • Giovanni Falcone,
  • Tiziana Esposito,
  • Carla Sardo and
  • Rita Patrizia Aquino

27 April 2022

Novel additive manufacturing (AM) techniques and particularly 3D printing (3DP) have achieved a decade of success in pharmaceutical and biomedical fields. Highly innovative personalized therapeutical solutions may be designed and manufactured through...

  • Article
  • Open Access
11 Citations
3,273 Views
15 Pages

Gelatin-Oxidized Nanocellulose Hydrogels Suitable for Extrusion-Based 3D Bioprinting

  • Shiyu Zhou,
  • Chenyang Han,
  • Zhongjin Ni,
  • Chao Yang,
  • Yihua Ni and
  • Yan Lv

27 October 2022

3D bioprinting is an emerging research field developed by the deep cross-fertilization of 3D printing technology with multiple disciplines such as mechanics, materials, and biomedicine. Extrusion 3D bioprinting, the most widely used 3D bioprinting te...

  • Article
  • Open Access
93 Citations
7,997 Views
13 Pages

Nailing of Layers: A Promising Way to Reinforce Concrete 3D Printing Structures

  • A. Perrot,
  • Y. Jacquet,
  • D. Rangeard,
  • E. Courteille and
  • M. Sonebi

26 March 2020

Today, the extrusion-based 3D printing of concrete is a potential breakthrough technology for the construction industry. It is expected that 3D printing will reduce the cost of construction of civil engineering structures (removal of formwork) and le...

  • Article
  • Open Access
22 Citations
5,940 Views
14 Pages

14 February 2021

Although bioabsorbable polymers have garnered increasing attention because of their potential in tissue engineering applications, to our knowledge there are only a few bioabsorbable 3D printed medical devices on the market thus far. In this study, we...

  • Review
  • Open Access
51 Citations
7,130 Views
24 Pages

Stem Cells and Extrusion 3D Printing for Hyaline Cartilage Engineering

  • Océane Messaoudi,
  • Christel Henrionnet,
  • Kevin Bourge,
  • Damien Loeuille,
  • Pierre Gillet and
  • Astrid Pinzano

22 December 2020

Hyaline cartilage is deficient in self-healing properties. The early treatment of focal cartilage lesions is a public health challenge to prevent long-term degradation and the occurrence of osteoarthritis. Cartilage tissue engineering represents a pr...

  • Article
  • Open Access
64 Citations
5,741 Views
16 Pages

23 October 2020

This study addressed the potential of 3D printing as a processing technology for delivering personalized healthy eating solutions to consumers. Extrusion-based 3D printing was studied as a tool to produce protein- and dietary fibre-rich snack product...

  • Article
  • Open Access
1,922 Views
32 Pages

The trade-off between resolution and speed represents a significant challenge when extrusion-based additive manufacturing (AM) is used for large-format additive manufacturing (LFAM). This paper presents an analysis of a new material extrusion process...

  • Article
  • Open Access
23 Citations
4,925 Views
16 Pages

13 April 2022

Plant-based meat analogues (PBMs) are increasingly interesting to customers because of their meat-like quality and contribution to a healthy diet. The single-screw extruder is an important method for processing PBMs, and the characteristics of the pr...

  • Article
  • Open Access
390 Views
24 Pages

Modeling and Optimization of Extruded Corn Product Fortification

  • Jelena Filipović,
  • Ivica Djalovic,
  • Milenko Košutić,
  • Milica Nićetin,
  • Biljana Lončar,
  • Miloš Radosavljević and
  • Vladimir Filipović

7 January 2026

The present study aimed to model and optimize the fortification of corn-based extruded flips with quinoa flour to improve their nutritional, functional, and sensory quality while maintaining desirable technological properties. Corn flour was partiall...

  • Review
  • Open Access
28 Citations
5,675 Views
20 Pages

Fused Filament Fabrication for Metallic Materials: A Brief Review

  • Jose M. Costa,
  • Elsa W. Sequeiros and
  • Manuel F. Vieira

5 December 2023

Fused filament fabrication (FFF) is an extrusion-based additive manufacturing (AM) technology mostly used to produce thermoplastic parts. However, producing metallic or ceramic parts by FFF is also a sintered-based AM process. FFF for metallic parts...

  • Article
  • Open Access
6 Citations
1,691 Views
18 Pages

24 July 2024

This study addresses critical challenges in the field of tissue engineering, specifically in the optimization of bioprinting technologies for the construction of complex, multicellular tissues. By utilizing a homemade piston-driven extrusion-based bi...

  • Review
  • Open Access
1 Citations
1,379 Views
20 Pages

Material Extrusion for Metals (MEX/M) has emerged as a cost-effective and versatile Additive Manufacturing technology (AM) for producing complex metal components. Despite its potential, parts realized via MEX/M suffer from significant limitations, pr...

  • Review
  • Open Access
120 Citations
11,046 Views
23 Pages

15 December 2023

The fused deposition modeling (FDM) process, an extrusion-based 3D printing technology, enables the manufacture of complex geometrical elements. This technology employs diverse materials, including thermoplastic polymers and composites as well as rec...

  • Article
  • Open Access
21 Citations
5,073 Views
13 Pages

Three-Dimensional Bioprinting with Alginate by Freeform Reversible Embedding of Suspended Hydrogels with Tunable Physical Properties and Cell Proliferation

  • Yuanjia Zhu,
  • Charles J. Stark,
  • Sarah Madira,
  • Sidarth Ethiraj,
  • Akshay Venkatesh,
  • Shreya Anilkumar,
  • Jinsuh Jung,
  • Seunghyun Lee,
  • Catherine A. Wu and
  • Yi-Ping Joseph Woo
  • + 2 authors

Extrusion-based three-dimensional (3D) bioprinting is an emerging technology that allows for rapid bio-fabrication of scaffolds with live cells. Alginate is a soft biomaterial that has been studied extensively as a bio-ink to support cell growth in 3...

  • Article
  • Open Access
7 Citations
3,149 Views
15 Pages

22 August 2024

The rapid advancement of 3D bioprinting has created a need for cost-effective and versatile 3D printers capable of handling bio-inks at various scales. This study introduces a novel framework for a specialized nozzle-holding device designed for an ex...

  • Article
  • Open Access
46 Citations
5,830 Views
27 Pages

Effects of Fiber Orientation on the Coefficient of Thermal Expansion of Fiber-Filled Polymer Systems in Large Format Polymer Extrusion-Based Additive Manufacturing

  • José Luis Colón Quintana,
  • Lucinda Slattery,
  • Jon Pinkham,
  • Joanna Keaton,
  • Roberto A. Lopez-Anido and
  • Keith Sharp

9 April 2022

Large format polymer extrusion-based additive manufacturing has been studied recently due to its capacity for high throughput, customizable bead size and geometry, and ability to manufacture large parts. Samples from three fiber-filled amorphous ther...

  • Article
  • Open Access
68 Citations
8,041 Views
18 Pages

Mechanical Recyclability of Polypropylene Composites Produced by Material Extrusion-Based Additive Manufacturing

  • Martin Spoerk,
  • Florian Arbeiter,
  • Ivan Raguž,
  • Clemens Holzer and
  • Joamin Gonzalez-Gutierrez

7 August 2019

Due to a lack of long-term experience with burgeoning material extrusion-based additive manufacturing technology, also known as fused filament fabrication (FFF), considerable amounts of expensive material will continue to be wasted until a defect-fre...

  • Article
  • Open Access
2 Citations
2,152 Views
13 Pages

This article discusses the prospects for using large-format ceramic stones in the construction of contemporary homes, as well as an overview of raw materials and technologies for production. The most promising technology is stiff extrusion with the a...

  • Article
  • Open Access
2 Citations
2,701 Views
16 Pages

Simulation and Optimization of Connection-Strength Performance of Axial Extrusion Joint

  • Jianguo Wu,
  • Jingyu Zhai,
  • Yangyang Yan,
  • Hongwei Lin,
  • Siquan Chen and
  • Jianping Luo

25 March 2022

Axial extrusion-connection technology is one of the important connection technologies for hydraulic piping systems, with high sealing performance and mechanical strength. In this paper, the finite-element-modeling method is used to simulate the exper...

  • Article
  • Open Access
21 Citations
3,710 Views
21 Pages

Effects of Printing Layer Orientation on the High-Frequency Bending-Fatigue Life and Tensile Strength of Additively Manufactured 17-4 PH Stainless Steel

  • Hamed Ghadimi,
  • Arash P. Jirandehi,
  • Saber Nemati,
  • Huan Ding,
  • Abdelrahman Garbie,
  • Jonathan Raush,
  • Congyuan Zeng and
  • Shengmin Guo

4 January 2023

In this paper, small blocks of 17-4 PH stainless steel were manufactured via extrusion-based bound powder extrusion (BPE)/atomic diffusion additive manufacturing (ADAM) technology in two different orientations. Ultrasonic bending-fatigue and uniaxial...

  • Review
  • Open Access
77 Citations
11,101 Views
14 Pages

It is imperative to develop organ manufacturing technologies based on the high organ failure mortality and serious donor shortage problems. As an emerging and promising technology, bioprinting has attracted more and more attention with its super prec...

  • Review
  • Open Access
133 Citations
16,410 Views
27 Pages

27 July 2018

One of the most widespread additive manufacturing (AM) technologies is fused deposition modelling (FDM), also known as fused filament fabrication (FFF) or extrusion-based AM. The main reasons for its success are low costs, very simple machine structu...

  • Review
  • Open Access
95 Citations
15,354 Views
20 Pages

4 September 2019

Additive manufacturing is one of the main topics of the fourth industrial revolution; defined as Industry 4.0. This technology offers several advantages related to the construction and architectural sectors; such as economic; environmental; social; a...

  • Review
  • Open Access
7 Citations
1,972 Views
24 Pages

An Overview of 3D Bioprinting Impact on Cell Viability: From Damage Assessment to Protection Solutions

  • Sara Manzoli,
  • Elena Merotto,
  • Martina Piccoli,
  • Pierangelo Gobbo,
  • Silvia Todros and
  • Piero G. Pavan

25 November 2025

Three-dimensional (3D) bioprinting has become a widely exploited tissue engineering technique for producing functional constructs that can mimic and replace native tissues. To this end, different printing strategies can be adopted, including inkjet-b...

  • Article
  • Open Access
26 Citations
4,681 Views
10 Pages

23 April 2021

Three-dimensional bioprinting has attracted much attention for biomedical applications, including wound dressing and tissue regeneration. The development of functional and easy-to-handle inks is expected to expand the applications of this technology....

  • Article
  • Open Access
12 Citations
5,564 Views
17 Pages

Mechanical Properties and Fatigue Performance of 17-4 PH Stainless Steel Manufactured by Atomic Diffusion Additive Manufacturing Technology

  • Jon Rodriguez,
  • Aitor Zuriarrain,
  • Aitor Madariaga,
  • Pedro J. Arrazola,
  • Erika Dominguez,
  • Itziar Fraile and
  • Daniel Soler

Additive Manufacturing (AM) is gaining importance as an alternative and complementary technology to conventional manufacturing processes. Among AM technologies, the Atomic Diffusion Additive Manufacturing (ADAM) technology is a novel extrusion-based...

  • Feature Paper
  • Review
  • Open Access
372 Citations
35,447 Views
42 Pages

29 March 2021

Polylactic acid (PLA) is the most widely used raw material in extrusion-based three-dimensional (3D) printing (fused deposition modeling, FDM approach) in many areas since it is biodegradable and environmentally friendly, however its utilization is l...

  • Review
  • Open Access
40 Citations
8,148 Views
33 Pages

Geopolymer Materials for Extrusion-Based 3D-Printing: A Review

  • Laura Ricciotti,
  • Antonio Apicella,
  • Valeria Perrotta and
  • Raffaella Aversa

12 December 2023

This paper examines how extrusion-based 3D-printing technology is evolving, utilising geopolymers (GPs) as sustainable inorganic aluminosilicate materials. Particularly, the current state of 3D-printing geopolymers is critically examined in this stud...

  • Article
  • Open Access
4 Citations
1,810 Views
17 Pages

Effect of Material Extrusion Method on the Microstructure and Mechanical Properties of Copper Parts

  • Naiara Aldeiturriaga,
  • Itziar Fraile,
  • Erika Dominguez,
  • Aitor Zuriarrain,
  • Pedro José Arrazola and
  • Daniel Soler

17 August 2024

In the present study, three extrusion-based Additive Manufacturing (AM) technologies were considered: Fused Filament Fabrication (FFF), Pellet Extrusion Process (PEP) and Atomic Diffusion Additive Manufacturing (ADAM). In order to compare these techn...

  • Article
  • Open Access
16 Citations
4,725 Views
13 Pages

Extrusion-Based 3D Printing for Highly Porous Alginate Materials Production

  • Natalia Menshutina,
  • Andrey Abramov,
  • Pavel Tsygankov and
  • Daria Lovskaya

14 July 2021

Three-dimensional (3D) printing is a promising technology for solving a wide range of problems: regenerative medicine, tissue engineering, chemistry, etc. One of the potential applications of additive technologies is the production of highly porous s...

  • Review
  • Open Access
110 Citations
15,351 Views
30 Pages

Current Advances in 3D Bioprinting Technology and Its Applications for Tissue Engineering

  • JunJie Yu,
  • Su A Park,
  • Wan Doo Kim,
  • Taeho Ha,
  • Yuan-Zhu Xin,
  • JunHee Lee and
  • Donghyun Lee

11 December 2020

Three-dimensional (3D) bioprinting technology has emerged as a powerful biofabrication platform for tissue engineering because of its ability to engineer living cells and biomaterial-based 3D objects. Over the last few decades, droplet-based, extrusi...

  • Review
  • Open Access
24 Citations
5,610 Views
16 Pages

19 December 2022

Three-dimensional printing technology enables the personalization and on-demand production of edible products of individual specifications. Four-dimensional printing technology expands the application scope of 3D printing technology, which controllab...

  • Review
  • Open Access
30 Citations
5,773 Views
27 Pages

Additive Manufacturing Applications in Biosensors Technologies

  • Abraham Abbey Paul,
  • Adedamola D. Aladese and
  • Robert S. Marks

23 January 2024

Three-dimensional (3D) printing technology, also known as additive manufacturing (AM), has emerged as an attractive state-of-the-art tool for precisely fabricating functional materials with complex geometries, championing several advancements in tiss...

  • Article
  • Open Access
6 Citations
3,691 Views
13 Pages

Fiber-reinforced 3D printing (3DP) technology is a recent addition to the material extrusion-based 3DP process unlocking huge potential to apply this technology for high-performance material fabrication with complex geometries. However, in order to t...

  • Article
  • Open Access
4 Citations
3,450 Views
26 Pages

Induction Heating of Laminated Composite Structures with Magnetically Responsive Nanocomposite Interlayers for Debonding-on-Demand Applications

  • Eleni Gkartzou,
  • Konstantinos Zafeiris,
  • Christos Tsirogiannis,
  • Alberto Pedreira,
  • Adrián Rodríguez,
  • Pablo Romero-Rodriguez,
  • Giorgos P. Gakis,
  • Tatjana Kosanovic-Milickovic,
  • Apostolos Kyritsis and
  • Costas A. Charitidis

30 September 2024

In the present study, the feasibility to achieve localized induction heating and debonding of multi-material composite structures is assessed in testing coupons prepared by Automated Fiber Placement (AFP) and extrusion-based additive manufacturing (A...

  • Article
  • Open Access
68 Citations
11,929 Views
26 Pages

Strength Properties of 316L and 17-4 PH Stainless Steel Produced with Additive Manufacturing

  • Slawomir Kedziora,
  • Thierry Decker,
  • Elvin Museyibov,
  • Julian Morbach,
  • Steven Hohmann,
  • Adrian Huwer and
  • Michael Wahl

9 September 2022

The number of additive manufacturing methods and materials is growing rapidly, leaving gaps in the knowledge of specific material properties. A relatively recent addition is the metal-filled filament to be printed similarly to the fused filament fabr...

  • Article
  • Open Access
11 Citations
5,786 Views
15 Pages

31 August 2023

Fused deposition modeling (FDM) technology is an emerging technology with promising applications, with the nozzle playing a crucial role in extrusion, heating, and material ejection. However, most current extrusion-based 3D printers handle only singl...

  • Review
  • Open Access
28 Citations
5,908 Views
26 Pages

3D Printing Direct Powder Extrusion in the Production of Drug Delivery Systems: State of the Art and Future Perspectives

  • Ángela Aguilar-de-Leyva,
  • Marta Casas,
  • Carmen Ferrero,
  • Vicente Linares and
  • Isidoro Caraballo

The production of tailored, on-demand drug delivery systems has gained attention in pharmaceutical development over the last few years, thanks to the application of 3D printing technology in the pharmaceutical field. Recently, direct powder extrusion...

  • Review
  • Open Access
294 Citations
26,367 Views
24 Pages

Gelatin-Based Hydrogels for Organ 3D Bioprinting

  • Xiaohong Wang,
  • Qiang Ao,
  • Xiaohong Tian,
  • Jun Fan,
  • Hao Tong,
  • Weijian Hou and
  • Shuling Bai

30 August 2017

Three-dimensional (3D) bioprinting is a family of enabling technologies that can be used to manufacture human organs with predefined hierarchical structures, material constituents and physiological functions. The main objective of these technologies...

  • Article
  • Open Access
239 Views
17 Pages

Fabrication and Performance Study of 3D-Printed MWCNTs/PDMS Flexible Piezoresistive Pressure Sensors

  • Haitao Liu,
  • Chenhui Sun,
  • Xiaoquan Shi,
  • Xubo Fan,
  • Junjun Liu and
  • Yazhou Sun

25 February 2026

Piezoresistive pressure sensing has broad application prospects in wearable fields such as human–machine interaction, physiological signal detection, and electronic skin. As a high-performance conductive filler, multi-walled carbon nanotubes (M...

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