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Materials 2016, 9(9), 756;

A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks

Singapore Centre for 3D Printing, School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798
Author to whom correspondence should be addressed.
Academic Editor: Nicole Zander
Received: 2 August 2016 / Revised: 29 August 2016 / Accepted: 30 August 2016 / Published: 6 September 2016
(This article belongs to the Special Issue 3D Printing for Biomedical Engineering)
Full-Text   |   PDF [4859 KB, uploaded 6 September 2016]   |  


Pneumatic extrusion-based bioprinting is a recent and interesting technology that is very useful for biomedical applications. However, many process parameters in the bioprinter need to be fully understood in order to print at an adequate resolution. In this paper, a simple yet accurate mathematical model to predict the printed width of a continuous hydrogel line is proposed, in which the resolution is expressed as a function of nozzle size, pressure, and printing speed. A thermo-responsive hydrogel, pluronic F127, is used to validate the model predictions. This model could provide a platform for future correlation studies on pneumatic extrusion-based bioprinting as well as for developing new bioink formulations. View Full-Text
Keywords: extrusion system; bioprinting; 3D printing; pluronic F-127; bioink extrusion system; bioprinting; 3D printing; pluronic F-127; bioink

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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    Description: Raw data and graph that show information about rheological properties and printing condition for both Pluronic 24.5%wt and 30%wt.

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Suntornnond, R.; Tan, E.Y.S.; An, J.; Chua, C.K. A Mathematical Model on the Resolution of Extrusion Bioprinting for the Development of New Bioinks. Materials 2016, 9, 756.

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