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Biodegradable Polymers and Stem Cells for Bioprinting

by Meijuan Lei 1 and Xiaohong Wang 1,2,*
Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
Center of 3D printing & Organ Manufacturing, Department of Tissue Engineering, China Medical University (CMU), Shenyang 110122, China
Author to whom correspondence should be addressed.
Academic Editors: Chee Kai Chua, Wai Yee Yeong and Jia An
Molecules 2016, 21(5), 539;
Received: 16 March 2016 / Revised: 12 April 2016 / Accepted: 13 April 2016 / Published: 29 April 2016
(This article belongs to the Special Issue Biomaterials and Bioprinting)
It is imperative to develop organ manufacturing technologies based on the high organ failure mortality and serious donor shortage problems. As an emerging and promising technology, bioprinting has attracted more and more attention with its super precision, easy reproduction, fast manipulation and advantages in many hot research areas, such as tissue engineering, organ manufacturing, and drug screening. Basically, bioprinting technology consists of inkjet bioprinting, laser-based bioprinting and extrusion-based bioprinting techniques. Biodegradable polymers and stem cells are common printing inks. In the printed constructs, biodegradable polymers are usually used as support scaffolds, while stem cells can be engaged to differentiate into different cell/tissue types. The integration of biodegradable polymers and stem cells with the bioprinting techniques has provided huge opportunities for modern science and technologies, including tissue repair, organ transplantation and energy metabolism. View Full-Text
Keywords: bioprinting; organ manufacturing; stem cells; gelatin based hydrogels; tissue engineering bioprinting; organ manufacturing; stem cells; gelatin based hydrogels; tissue engineering
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Lei, M.; Wang, X. Biodegradable Polymers and Stem Cells for Bioprinting. Molecules 2016, 21, 539.

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