77 Results Found

Few studies have focused on elderly (>80 years) amyotrophic lateral sclerosis (ALS) patients, who represent a fragile subgroup generally not included in clinical trials and often neglected because they are more difficult to diagnose and manage. We...

Chiu et al. report in their paper “Health Promotion and Disease Prevention Interventions for the Elderly: A Scoping Review from 2015–2019” [...]

Background/Objectives: The systematic review by Zaher-Sánchez et al. evaluated the effectiveness of pharmacological and non-pharmacological interventions in preventing and managing delirium in elderly patients admitted to intensive care units...

Quelle Descoutures F, Vahanian A, et al. Contemporary surgical or percutaneous management of severe aortic stenosis in the elderly [...]

Perioperative neurocognitive disorder (PND) is a growing concern, affecting several million elderly patients each year in the United States, but strategies for its effective prevention have not yet been established. Humeidan et al. recently demonstra...

Neurodegenerative diseases, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are among the major health problems of the elderly, and represent a major global health challenge due to th...

Background: Amyotrophic Lateral Sclerosis (ALS) is a degenerative disorder which affects the motor neurons. Growing evidence suggests that ALS may impact the metabolic system, including the glucose metabolism. Several studies investigated the role of...

The Older People’s Quality of Life Questionnaire (OPQOL-35) is a validated tool used to measure quality of life in the older people in many countries. The study describes the linguistic validation, cultural adaption, and pilot testing of the Al...

Dehydration is common among elderly people. The aim of this study was to perform validation analysis of a geriatric dehydration-screening tool (DST) in the assessment of hydration status in elderly people. This tool was based on the DST proposed by V...

Mobile health (mHealth) is a branch of electronic health (eHealth) technology that provides healthcare services using smartphones and wearable devices. However, most mHealth applications were developed without applying mHealth specialized usability g...

Background: Expanding dental care coverage for the elderly is globally recommended but not widely implemented due to its high costs and intangible benefits. Methods: This study examined the impact of such an expansion in Korea using the imputation-ba...

Being characterized by progressive and severe damage in neuronal cells, neurodegenerative diseases (NDDs) are the major cause of disability and morbidity in the elderly, imposing a significant economic and social burden. As major components of the ce...

Objective: The aim of this study was the verification of the Subdural Hematoma in the Elderly (SHE) score proposed by Alford et al. as a mortality predictor in patients older than 65 years with nontraumatic/minor trauma acute subdural hematoma (aSDH)...

Cardiac involvement is the most important factor determining prognosis in patients with systemic amyloidosis. This retrospective observational study of 98 patients with amyloidosis was undertaken to assess the amyloid types that are most likely to af...

Introduction: Prediction equations proposed by the European Community of Steel and Coal (ECSC) and the European Respiratory Society (ERS) or those proposed by Falaschetti et al. for the English population are currently recommended for use in Poland....

Cardiac amyloidosis (CA) results mainly from the infiltration of the myocardium by either immunoglobulin light-chain fibrils (AL) or transthyretin fibrils (ATTR), causing restrictive cardiomyopathy and eventually death if untreated. AL derives from m...

Awareness of design when planning public urban spaces assumes particular importance through its mission to meet the diverse needs of the different segments within the community. The elderly is considered one of the pivotal segments, with their influe...

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder more prevalent among the elderly population. AD is characterised clinically by a progressive decline in cognitive functions and pathologically by the presence of neurofibrilla...

This study addresses the critical challenge of optimizing spatial arrangements for the elderly in rapidly aging societies. It investigates the proximity preference preferences among nine types of facilities frequently used by senior citizens in Dubai...

Tooth wear (TW) is an irreversible and cumulative phenomenon causing aesthetic and functional compromise. Increasing wear has been associated with age, and various other factors have been reported to influence its type and/or severity both in individ...

As osteoarthritis is a common disease in elderly people and large cartilage defects can only be treated by joint replacement surgery, a scaffold is seen as a potential treatment that could help patients to delay or avoid surgery. An ideal scaffold sh...

The purpose of this study was to assess the impact of food texture, oral processing, bolus characteristics, and in vitro digestive conditions on the starch and protein digestibility of al dente and soft-cooked commercial red lentil pasta. For that, s...

Respiratory syncytial virus (RSV) is a major pathogen that causes severe lower respiratory tract infection in infants, the elderly and the immunocompromised worldwide. At present no approved specific drugs or vaccines are available to treat this path...

Human metapneumovirus (hMPV), first described in 2001 [1], is responsible for causing serious respiratory illness in young children, the elderly and immunocompromised patients. Four distinct lineages of hMPV have been identified with the original nom...

Different types of amyloid concomitantly present in the same patient is believed to be improbable. We reported four cases of patients with plasma cell disorders who were found to have biopsy proven concomitant different types of amyloid fibrils depos...

Increasingly, research on the aging process tends to adopt a dual perspective emic (specific to a culture) and etic (universal), requiring further studies to address this cross-cultural approach. The aim is to obtain an empirical answer to the questi...

(1) Purpose: Quantitative magnetic resonance imaging (qMRI) measurements can be used to sensitively estimate brain morphological alterations and may support clinical diagnosis of neurodegenerative diseases (ND). We aimed to establish a normative refe...

This research analyzed the relationship between extreme heat and Emergency Medical Service (EMS) calls in King County, WA, USA between 2007 and 2012, including the effect of community-level characteristics. Extreme heat thresholds for the Basic Life...

Background: Emerging evidence suggests an intricate relationship between vitamin D, Ca2+, and inflammation-driven anemia. We, thus, investigated the patterns of serum 25(OH)D3, Ca2+, ferritin, and iron in healthy and anemic members of the Saudi popul...

Since 2018, Al-Ahsa Oasis has become a UNESCO site because of the integration of the natural, agricultural, and cultural elements. The objective of this research is to investigate land cover changes (LCC) in this region and the key sustainability fac...

Osteoporosis, a terminal illness, has emerged as a global public health problem in recent years. The long-term use of bone anabolic drugs to treat osteoporosis causes multi-morbidity in elderly patients. Alternative therapies, such as allogenic and a...

Background: Noncommunicable chronic diseases (NCDs) are multifaceted, and the health implications of the COVID-19 pandemic are far-reaching, especially for NCDs. Physical distancing and quarantine can lead to the poor management of NCDs because the v...

The simultaneous use of multiple drugs—termed ‘polypharmacy’—is often required to manage multiple physiological and biological changes and the interplay between chronic disorders that are expected to increase in association wi...

Urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms are prevalent in both outpatient and inpatient settings, representing the most often encountered forms of infection. This research aimed to estimate...

This research study aimed to investigate the association between demographic and operational factors and emergency medical services (EMS) missions ending in non-conveyance (NC) due to patient-initiated refusal (PIR). We conducted a retrospective popu...

The prevalence of cardiac amyloidosis (CA), especially as a cause of heart failure, has significantly increased in recent years. Early detection and accurate assessment of the disease burden are crucial for initiating timely treatment and ensuring pr...

Activities of Daily Living systems (ADLs) and the User Interface (UI) design principles used to implement them empowers the elderly to continue living a normal daily routine. The daily monitoring of activities for most Assisted Living (AL) systems de...

Heart Failure with Preserved Ejection Fraction (HFpEF) is one of the most frequent causes of heart failure in the world’s population (about 19–55%), and is commonly associated with a high rate of hospitalization (almost 70–80%) and...

Neurodegenerative diseases are progressive disorders that affect the central nervous system (CNS) and represent the major cause of premature death in the elderly. One of the possible determinants of neurodegeneration is the change in mitochondrial fu...

The number of elderly people is projected to double in the next 50 years worldwide, resulting in an increased prevalence of neurodegenerative diseases. Aging causes changes in brain tissue homeostasis, thus contributing to the development of neurodeg...

Background: Cardiac amyloidosis (CA) could be a common cause of heart failure (HF). The objective of the study was to estimate the prevalence of CA in patients with HF. Methods: Observational, prospective, and multicenter study involving 30 Spanish h...

Alzheimer’s disease (AD) is an intractable neurodegenerative disease that leads to dementia, primarily in elderly people. The neurotoxicity of amyloid-beta (Aβ) and tau protein has been demonstrated over the last two decades. In line with these findi...

The proportion of geriatric depression recorded in Vietnam was 66.9%. Depression in older people is a risk factor for problems related to dementia, poor quality of life, and suicide. To have a good Vietnamese questionnaire for assessing geriatric dep...

We read with great interest the case report by Fierro et al. [...]

The journal retracts the article titled “Obesity and Frailty Syndrome in the Elderly: Prospective Study in Primary Care” [...]

Alzheimer’s disease (AD) is characterized by the deposition of senile plaques (SPs) and the formation of neurofibrillary tangles (NTFs), as well as neuronal dysfunctions in the brain, but in fact, patients have shown a sustained disease progres...

This study was conducted to identify the factors associated with frailty according to gender of older adults living alone in Korea. Data from the National Survey of the Living Conditions of Korean Elderly in 2017 were used. Participants were 2340 old...

Stroke, amyotrophic lateral sclerosis (ALS), and Parkinson’s disease are some of the conditions that can lead to neuromotor disabilities requiring rehabilitation. To address the socio-economic burden that is amplified by the rapidly increasing...

This study proposes an innovative health management solution to address the defecation care needs of the elderly population. Traditional post-defecation care methods have significant limitations, particularly imposing a considerable psychological bur...

This paper describes a malaria knowledge test (MKT) developed to evaluate a web-based game for students who increasingly travel to malaria- risk regions of the world. The 18-item MKT was structured according to the dimensions of the self-regulation...