Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Population
2.2. Statistical Analysis
3. Results
3.1. Effect of Gender and Age on 25(OH)D3 and Ca2+ Levels
3.2. Effect of Gender and Age on Ferritin and Iron Levels
3.3. Distribution of Hb Level in Study Subjects
3.4. Patterns of Serum 25(OH)D3 in Anemic Subjects
3.5. Patterns of Serum Ca2+ in Anemic Subjects
3.6. Patterns of Serum Ferritin in Anemic Subjects
3.7. Patterns of Serum Iron in Anemic Subjects
3.8. Prevalence of Serum 25(OH)D3, Ca2+, Ferritin, and Iron Disturbances in Anemia
3.9. Association of Serum 25(OH)D3, Ca2+, Ferritin, and Iron Disturbances in Anemia
3.10. Risk Assessment of Serum 25(OH)D3, Total Ca2+, Ferritin, and Iron
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Age Group | Range (Years) | No. of Subjects |
---|---|---|
Males | ||
Young | 0–17 | 435 |
Young adults * | 18–39 | 2358 |
Adults | 40–64 | 2599 |
Elderlies | 65–110 | 563 |
Females | ||
Young | 0–17 | 430 |
Young adults * | 18–39 | 4320 |
Adults | 40–64 | 2870 |
Elderlies | 65–110 | 629 |
Condition | Prevalence (%) | ||
---|---|---|---|
All Subjects | Healthy | Anemic | |
VDD | 98.47 | 98.49 | 98.34 |
Hypocalcemia | 0.80 | 0.57 | 1.87 |
Hypercalcemia | 2.40 | 2.68 | 1.06 |
Ferritin deficiency | 51.11 | 40.32 | 90.70 |
Iron deficiency | 36.36 | 35.67 | 40.74 |
Condition | PR | 95% CI | p | OR | 95% CI | p |
---|---|---|---|---|---|---|
VDD | 0.92 | 0.69–1.22 | 0.5749 | 0.90 | 0.64–1.27 | 0.5782 |
Hypocalcemia | 2.36 | 1.88–2.95 | <0.0001 | 3.32 | 2.27–4.86 | <0.0001 |
Hypercalcemia | 0.42 | 0.10–1.70 | 0.2257 | 0.42 | 0.10–1.70 | 0.2240 |
Ferritin deficiency | 9.33 | 6.27–13.87 | <0.0001 | 14.44 | 9.38–22.22 | <0.0001 |
Iron deficiency | 1.20 | 0.59–2.44 | 0.6102 | 1.24 | 0.54–2.84 | 0.6114 |
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Alfhili, M.A.; Basudan, A.M.; Alfaifi, M.; Awan, Z.A.; Algethami, M.R.; Alsughayyir, J. Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study. Life 2022, 12, 2119. https://doi.org/10.3390/life12122119
Alfhili MA, Basudan AM, Alfaifi M, Awan ZA, Algethami MR, Alsughayyir J. Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study. Life. 2022; 12(12):2119. https://doi.org/10.3390/life12122119
Chicago/Turabian StyleAlfhili, Mohammad A., Ahmed M. Basudan, Mohammed Alfaifi, Zuhier A. Awan, Mohammed R. Algethami, and Jawaher Alsughayyir. 2022. "Patterns of 25-Hydroxyvitamin D3, Calcium Status, and Anemia in the Saudi Population: A Cross-Sectional Study" Life 12, no. 12: 2119. https://doi.org/10.3390/life12122119