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  • Article
  • Open Access
1 Citations
1,569 Views
27 Pages

26 November 2024

Design floods are traditionally estimated based on the at-site annual maximum flood series, including historical information of hydraulic structures. Nevertheless, the construction and operation of upstream reservoirs undermine the assumption of stat...

  • Review
  • Open Access
9 Citations
5,957 Views
50 Pages

Comprehensive Review on Synthesis, Properties, and Applications of Phosphorus (PIII, PIV, PV) Substituted Acenes with More Than Two Fused Benzene Rings

  • Marek Koprowski,
  • Krzysztof Owsianik,
  • Łucja Knopik,
  • Vivek Vivek,
  • Adrian Romaniuk,
  • Ewa Różycka-Sokołowska and
  • Piotr Bałczewski

5 October 2022

This comprehensive review, covering the years 1968–2022, is not only a retrospective investigation of a certain group of linearly fused aromatics, called acenes, but also a presentation of the current state of the knowledge on the synthesis, re...

  • Article
  • Open Access
1 Citations
2,525 Views
14 Pages

12 April 2023

Recently, increasing attention has been paid to sheep milk products, which are high in saturated fatty acids (SFA), and the extent of their impact on human health. This study aimed to identify SNPs for PI, PIII, and Exon 53 in the ACACα gene an...

  • Article
  • Open Access
3 Citations
1,380 Views
20 Pages

Thermal Evolution of Expanded Phases Formed by PIII Nitriding in Super Duplex Steel Investigated by In Situ Synchrotron Radiation

  • Bruna Corina Emanuely Schibicheski Kurelo,
  • João Frederico Haas Leandro Monteiro,
  • Gelson Biscaia de Souza,
  • Francisco Carlos Serbena,
  • Carlos Maurício Lepienski,
  • Rodrigo Perito Cardoso and
  • Silvio Francisco Brunatto

5 December 2024

The Plasma Immersion Ion Implantation (PIII) nitriding was used to form a modified layer rich in expanded austenite (γN) and expanded ferrite (αN) phases in super duplex steel. The thermal stability of these phases was investigated throug...

  • Article
  • Open Access
13 Citations
4,473 Views
10 Pages

25 March 2019

TiAlSiN coatings were deposited on YT 15 cemented carbide substrate by reactive direct current magnetron sputtering (DCMS) in a Plasma Immersion Ion Implantation and Deposition (PIII&D) system. The pre-implantation step and the coating deposition...

  • Article
  • Open Access
623 Views
18 Pages

5 December 2025

The lower Yellow River, characterized by high sediment concentration and complex channel evolution, faces a persistent challenge of maintaining erosion–deposition balance. Using long-term hydrological and cross-sectional data (1950–2022)...

  • Feature Paper
  • Article
  • Open Access
12 Citations
6,287 Views
20 Pages

Improved Adhesion of the DLC Coating Using HiPIMS with Positive Pulses and Plasma Immersion Pretreatment

  • Iñigo Gómez,
  • Adrián Claver,
  • José Antonio Santiago,
  • Iván Fernandez,
  • Jose Fernandez Palacio,
  • Cristina Diaz,
  • Stephan Mändl and
  • Jose Antonio Garcia

5 September 2021

Diamond-like carbon (DLC) coatings are used due to their extraordinary tribomechanical properties, great hardness, high elastic modulus, high wear resistance, low friction coefficient and chemical inertness, which provide them with biocompatibility....

  • Review
  • Open Access
11 Citations
4,341 Views
14 Pages

Uniqueness of RNA Coliphage Qβ Display System in Directed Evolutionary Biotechnology

  • Godwin W. Nchinda,
  • Nadia Al-Atoom,
  • Mamie T. Coats,
  • Jacqueline M. Cameron and
  • Alain B. Waffo

27 March 2021

Phage display technology involves the surface genetic engineering of phages to expose desirable proteins or peptides whose gene sequences are packaged within phage genomes, thereby rendering direct linkage between genotype with phenotype feasible. Th...

  • Short Note
  • Open Access
2,309 Views
5 Pages

N-(diisopropylphosphanyl)benzamide

  • María M. Alcaide,
  • Daniel García Garrido,
  • Eleuterio Álvarez and
  • Riccardo Peloso

10 June 2023

N-(diisopropylphosphanyl)benzamide, PhC(O)NHPiPr2, has been synthesized in good yield following two alternative procedures that employ benzamide as the starting material. The first one is a two-step preparation, in which N-(trimetilsilyl)benzamide is...

  • Article
  • Open Access
12 Citations
7,246 Views
16 Pages

Oxidation Behavior of Zr–1Nb Corroded in Air at 400 °C after Plasma Immersion Titanium Implantation

  • Aleksei Obrosov,
  • Alina N. Sutygina,
  • Anton Manakhov,
  • Sebastian Bolz,
  • Sabine Weiß and
  • Egor B. Kashkarov

2 January 2018

In this paper, the influence of plasma immersion titanium implantation into the zirconium alloy Zr-1Nb on the oxidation behavior at 400 °C for 5, 24, 72, and 240 h in air under normal atmospheric pressure (101.3 kPa) was shown. The influence of impla...

  • Article
  • Open Access
8 Citations
3,754 Views
19 Pages

Examination of the Efficacy and Cross-Reactivity of a Novel Polyclonal Antibody Targeting the Disintegrin Domain in SVMPs to Neutralize Snake Venom

  • Shelby S. Szteiter,
  • Ilse N. Diego,
  • Jonathan Ortegon,
  • Eliana M. Salinas,
  • Abcde Cirilo,
  • Armando Reyes,
  • Oscar Sanchez,
  • Montamas Suntravat,
  • Emelyn Salazar and
  • Jacob A. Galan
  • + 1 author

31 March 2021

Snake envenomation can result in hemorrhage, local necrosis, swelling, and if not treated properly can lead to adverse systemic effects such as coagulopathy, nephrotoxicity, neurotoxicity, and cardiotoxicity, which can result in death. As such, snake...

  • Article
  • Open Access
1 Citations
3,847 Views
16 Pages

New Phosphonite Ligands with High Steric Demand and Low Basicity: Synthesis, Structural Properties and Cyclometalated Complexes of Pt(II)

  • María M. Alcaide,
  • Matteo Pugliesi,
  • Eleuterio Álvarez,
  • Joaquín López-Serrano and
  • Riccardo Peloso

Two phosphonite ligands bearing the highly sterically demanding 2,6-bis (2,6-dimethylphenyl)phenyl group (ArXyl2), PArXyl2(OPhNO2)2 and PArXyl2(OPhNO2,Me)2, were prepared from the parent dihalophosphines PArXyl2X2 (X = Cl, Br) and the corresponding p...

  • Review
  • Open Access
10 Citations
2,882 Views
27 Pages

13 October 2022

Enhanced in vitro corrosion resistance, cytocompatibility, in vitro antibacterial activities, in vivo antibacterial activities, in vivo corrosion resistance and in vivo stimulation of bone formation on plasma-modified biodegradable Mg and its alloys...

  • Article
  • Open Access
12 Citations
8,966 Views
16 Pages

24 April 2018

Ethylene-propylene diene monomer rubber (EPDM) was treated by plasma immersion ion implantation (PIII) with nitrogen ions of 20 keV energy and fluence from 1013 to 1016 ions/cm2. The Fourier-transform infrared attenuated total reflection spectra, ato...

  • Article
  • Open Access
5 Citations
8,776 Views
11 Pages

Silicon Heterojunction Solar Cells Using AlOx and Plasma-Immersion Ion Implantation

  • Yu-Hsien Lin,
  • Yung-Chun Wu,
  • Hsin-Chiang You,
  • Chun-Hao Chen,
  • Ping-Hua Chen,
  • Yi-He Tsai,
  • Yi-Yun Yang and
  • K. S. Chang-Liao

13 June 2014

Aluminum oxide (AlOx) and plasma immersion ion implantation (PIII) were studied in relation to passivated silicon heterojunction solar cells. When aluminum oxide (AlOx) was deposited on the surface of a wafer; the electric field near the surface of w...

  • Article
  • Open Access
13 Citations
3,364 Views
10 Pages

Corrosion Resistance of AISI 316L Stainless Steel Biomaterial after Plasma Immersion Ion Implantation of Nitrogen

  • Viera Zatkalíková,
  • Juraj Halanda,
  • Dušan Vaňa,
  • Milan Uhríčik,
  • Lenka Markovičová,
  • Milan Štrbák and
  • Lenka Kuchariková

10 November 2021

Plasma immersion ion implantation (PIII) of nitrogen is low-temperature surface technology which enables the improvement of tribological properties without a deterioration of the corrosion behavior of austenitic stainless steels. In this paper the co...

  • Article
  • Open Access
7 Citations
2,473 Views
15 Pages

Identification of Expanded Austenite in Nitrogen-Implanted Ferritic Steel through In Situ Synchrotron X-ray Diffraction Analyses

  • Bruna C. E. Schibicheski Kurelo,
  • Carlos M. Lepienski,
  • Willian R. de Oliveira,
  • Gelson B. de Souza,
  • Francisco C. Serbena,
  • Rodrigo P. Cardoso,
  • Julio C. K. das Neves and
  • Paulo C. Borges

14 October 2023

The existence and formation of expanded austenite in ferritic stainless steels remains a subject of debate. This research article aims to provide comprehensive insights into the formation and decomposition of expanded austenite through in situ struct...

  • Article
  • Open Access
26 Citations
5,940 Views
19 Pages

Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing

  • Amilton Iatecola,
  • Guilherme Arthur Longhitano,
  • Luiz Henrique Martinez Antunes,
  • André Luiz Jardini,
  • Emilio de Castro Miguel,
  • Miloslav Béreš,
  • Carlos Salles Lambert,
  • Tiago Neves Andrade,
  • Rogério Leone Buchaim and
  • Marcelo Rodrigues da Cunha
  • + 6 authors

Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. H...

  • Article
  • Open Access
3 Citations
3,108 Views
28 Pages

A Novel P-III Metalloproteinase from Bothrops barnetti Venom Degrades Extracellular Matrix Proteins, Inhibits Platelet Aggregation, and Disrupts Endothelial Cell Adhesion via α5β1 Integrin Receptors to Arginine–Glycine–Aspartic Acid (RGD)-Containing Molecules

  • Pedro Henrique de Caires Schluga,
  • Debora Larangote,
  • Ana Maria de Melo,
  • Guilherme Kamienski Lobermayer,
  • Daniel Torrejón,
  • Luciana Souza de Oliveira,
  • Valeria Gonçalves Alvarenga,
  • Dan Erick Vivas-Ruiz,
  • Silvio Sanches Veiga and
  • Luiza Helena Gremski
  • + 1 author

9 November 2024

Viperid snake venoms are notably abundant in metalloproteinases (proteins) (SVMPs), which are primarily responsible for inducing hemorrhage and disrupting the hemostatic process and tissue integrity in envenomed victims. In this study, barnettlysin-I...

  • Article
  • Open Access
5 Citations
2,088 Views
24 Pages

A photonic integrated interference imaging system (PIIIS) is a computational imager based on Michelson interference and photonic integrated circuits (PICs). In this paper, a PIIIS based on a compact sampling lenslet array that can sample the zero spa...

  • Feature Paper
  • Article
  • Open Access
16 Citations
7,389 Views
13 Pages

A Cell-Adhesive Plasma Polymerized Allylamine Coating Reduces the In Vivo Inflammatory Response Induced by Ti6Al4V Modified with Plasma Immersion Ion Implantation of Copper

  • Uwe Walschus,
  • Andreas Hoene,
  • Maciej Patrzyk,
  • Silke Lucke,
  • Birgit Finke,
  • Martin Polak,
  • Gerold Lukowski,
  • Rainer Bader,
  • Carmen Zietz and
  • Michael Schlosser
  • + 2 authors

Copper (Cu) could be suitable to create anti-infective implants based on Titanium (Ti), for example by incorporating Cu into the implant surface using plasma immersion ion implantation (Cu-PIII). The cytotoxicity of Cu might be circumvented by an add...

  • Article
  • Open Access
47 Citations
7,274 Views
20 Pages

Insights into the Mechanisms Involved in Strong Hemorrhage and Dermonecrosis Induced by Atroxlysin-Ia, a PI-Class Snake Venom Metalloproteinase

  • Luciana Aparecida Freitas-de-Sousa,
  • Mônica Colombini,
  • Mônica Lopes-Ferreira,
  • Solange M. T. Serrano and
  • Ana Maria Moura-da-Silva

2 August 2017

Hemorrhage is the most prominent effect of snake venom metalloproteinases (SVMPs) in human envenomation. The capillary injury is a multifactorial effect caused by hydrolysis of the components of the basement membrane (BM). The PI and PIII classes of...

  • Article
  • Open Access
5 Citations
3,788 Views
17 Pages

Plasma Surface Engineering to Biofunctionalise Polymers for β-Cell Adhesion

  • Clara Tran,
  • Nicole Hallahan,
  • Elena Kosobrodova,
  • Jason Tong,
  • Peter Thorn and
  • Marcela Bilek

8 September 2021

Implant devices containing insulin-secreting β-cells hold great promise for the treatment of diabetes. Using in vitro cell culture, long-term function and viability are enhanced when β-cells are cultured with extracellular matrix (ECM) proteins. Here...

  • Feature Paper
  • Article
  • Open Access
35 Citations
8,537 Views
13 Pages

25 December 2015

Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B. diporus, is widely distributed throughout the country, but principally found...

  • Review
  • Open Access
20 Citations
9,054 Views
11 Pages

4 August 2017

Snake venom metalloproteinases (SVMP) are widely distributed among the venoms of Crotalinae and Viperidae, and are organized into three classes (P-I, P-II and P-III) according to their size and domain structure. P-I SVMP are the smallest SVMP, as the...

  • Article
  • Open Access
4 Citations
3,695 Views
15 Pages

Feeding Behavior of Finishing Pigs under Diurnal Cyclic Heat Stress

  • Marllon José Karpeggiane de Oliveira,
  • Marcio Valk,
  • Antônio Diego Brandão Melo,
  • Danilo Alves Marçal,
  • Cleslei Alisson Silva,
  • Graziela Alves da Cunha Valini,
  • Pedro Righetti Arnaut,
  • Joseane Penteado Rosa Gonçalves,
  • Ines Andretta and
  • Luciano Hauschild

2 March 2023

The impact of cyclic heat stress (CHS) and turning the lights on and off on pig feeding behavior (FB) was investigated. The FB of 90 gilts was recorded in real-time under two ambient temperatures (AT): thermoneutrality (TN, 22 °C) or CHS (22/35 &...

  • Article
  • Open Access
21 Citations
7,202 Views
23 Pages

18 November 2014

Drought & flood events, especially the drought & flood combination events (DFCEs) on the North China Plain (NCP), known as an important grain production region in China, constitute a serious threat to China’s food security. Studies on DFCEs i...

  • Article
  • Open Access
13 Citations
3,941 Views
14 Pages

Modulation of Adhesion Molecules Expression by Different Metalloproteases Isolated from Bothrops Snakes

  • Bianca C. Zychar,
  • Patrícia B. Clissa,
  • Eneas Carvalho,
  • Adilson S. Alves,
  • Cristiani Baldo,
  • Eliana L. Faquim-Mauro and
  • Luís Roberto C. Gonçalves

15 November 2021

Snake venom metalloproteinases (SVMP) are involved in local inflammatory reactions observed after snakebites. Based on domain composition, they are classified as PI (pro-domain + proteolytic domain), PII (PI + disintegrin-like domains), or PIII (PII...

  • Article
  • Open Access
14 Citations
3,510 Views
17 Pages

Protecting Orthopaedic Implants from Infection: Antimicrobial Peptide Mel4 Is Non-Toxic to Bone Cells and Reduces Bacterial Colonisation When Bound to Plasma Ion-Implanted 3D-Printed PAEK Polymers

  • Hedi Verena Kruse,
  • Sudip Chakraborty,
  • Renxun Chen,
  • Naresh Kumar,
  • Muhammad Yasir,
  • William T. Lewin,
  • Natalka Suchowerska,
  • Mark D. P. Willcox and
  • David R. McKenzie

9 April 2024

Even with the best infection control protocols in place, the risk of a hospital-acquired infection of the surface of an implanted device remains significant. A bacterial biofilm can form and has the potential to escape the host immune system and deve...

  • Article
  • Open Access
11 Citations
5,276 Views
21 Pages

Genomic Confirmation of the P-IIIe Subclass of Snake Venom Metalloproteinases and Characterisation of Its First Member, a Disintegrin-Like/Cysteine-Rich Protein

  • Kity Požek,
  • Adrijana Leonardi,
  • Jože Pungerčar,
  • Weiqiao Rao,
  • Zijian Gao,
  • Siqi Liu,
  • Andreas Hougaard Laustsen,
  • Alenka Trampuš Bakija,
  • Katarina Reberšek and
  • Igor Križaj
  • + 1 author

23 March 2022

Disintegrin-like/cysteine-rich (DC) proteins have long been regarded just as products of proteolysis of P-III snake venom metalloproteinases (SVMPs). However, here we demonstrate that a DC protein from the venom of Vipera ammodytes (Vaa; nose-horned...

  • Review
  • Open Access
14 Citations
7,884 Views
27 Pages

Synthetic Strategies for Dinucleotides Synthesis

  • Lucie Appy,
  • Crystalle Chardet,
  • Suzanne Peyrottes and
  • Béatrice Roy

27 November 2019

Dinucleoside 5′,5′-polyphosphates (DNPs) are endogenous substances that play important intra- and extracellular roles in various biological processes, such as cell proliferation, regulation of enzymes, neurotransmission, platelet disaggre...

  • Article
  • Open Access
29 Citations
9,355 Views
16 Pages

8 February 2019

Wettability is an important property of solid surfaces and is widely used in many industries. In this work, seven silicon microstructure surfaces were made by plasma immersion ion implantation (PIII) technology. The experimental contact angles and th...

  • Article
  • Open Access
1,732 Views
17 Pages

Constrained Phosphine Chalcogenide Selenoethers Supported by peri-Substitution

  • Anna E. Tarcza,
  • Alexandra M. Z. Slawin,
  • Cameron L. Carpenter-Warren,
  • Michael Bühl,
  • Petr Kilian and
  • Brian A. Chalmers

27 October 2023

A series of phosphorus and selenium peri-substituted acenaphthene species with the phosphino group oxidized by O, S, and Se has been isolated and fully characterized, including by single-crystal X-ray diffraction. The P(V) and Se(II) systems showed f...

  • Review
  • Open Access
21 Citations
17,790 Views
47 Pages

21 September 2009

Ion implantation, a common technology in semiconductor processing, has been applied to biomaterials since the 1960s. Using energetic ion bombardment, a general term which includes conventional ion implantation plasma immersion ion implantation (PIII)...

  • Article
  • Open Access
10 Citations
3,028 Views
18 Pages

3 September 2023

Manganese (Mn) is an essential micronutrient in various physiological processes, but its functions in bone metabolism remain undefined. This is partly due to the interplay between immune and bone cells because Mn plays a central role in the immune sy...

  • Article
  • Open Access
94 Citations
10,497 Views
18 Pages

9 March 2018

The arctic strain of Chlorella sp. (Chlorella-Arc) exists in the coldest and driest arctic ecosystems, and it is a new resource of active polysaccharides. The extraction of crude polysaccharide from Chlorella-Arc was optimized using the response surf...

  • Review
  • Open Access
86 Citations
11,406 Views
26 Pages

Recent Progress of Black Silicon: From Fabrications to Applications

  • Zheng Fan,
  • Danfeng Cui,
  • Zengxing Zhang,
  • Zhou Zhao,
  • Hongmei Chen,
  • Yanyun Fan,
  • Penglu Li,
  • Zhidong Zhang,
  • Chenyang Xue and
  • Shubin Yan

26 December 2020

Since black silicon was discovered by coincidence, the special material was explored for many amazing material characteristics in optical, surface topography, and so on. Because of the material property, black silicon is applied in many spheres of a...

  • Review
  • Open Access
17 Citations
5,182 Views
27 Pages

23 September 2022

Organophosphorus ligands are an invaluable family of compounds that continue to underpin important roles in disciplines such as coordination chemistry and catalysis. Their success can routinely be traced back to facile tuneability thus enabling a hig...

  • Review
  • Open Access
24 Citations
6,750 Views
17 Pages

31 October 2022

Dental implants have been widely applied in partially and fully edentulous patients and have shown predictable clinical outcomes, but there are still many cases of implant failures, such as osseointegration failure and peri-implant inflammation. To i...

  • Article
  • Open Access
14 Citations
4,824 Views
27 Pages

19 February 2021

This research is focused on a synthesis of copper-cellulose phosphates antimicrobial complexes. Vapor-phase phosphorylations of cellulose were achieved by exposing microcrystalline cellulose to phosphorus trichloride (PCl3) vapors. The cellulose-O-di...

  • Article
  • Open Access
42 Citations
8,537 Views
19 Pages

Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus)

  • Stephen P. Mackessy,
  • Jamie Leroy,
  • Estrella Mociño-Deloya,
  • Kirk Setser,
  • Robert W. Bryson and
  • Anthony J. Saviola

3 July 2018

As trophic adaptations, rattlesnake venoms can vary in composition depending on several intrinsic and extrinsic factors. Ontogenetic changes in venom composition have been documented for numerous species, but little is known of the potential age-rela...

  • Feature Paper
  • Article
  • Open Access
20 Citations
8,258 Views
32 Pages

12 July 2016

The molecular events underlying the evolution of the Snake Venom Metalloproteinase (SVMP) family from an A Disintegrin And Metalloproteinase (ADAM) ancestor remain poorly understood. Comparative genomics may provide decisive information to reconstruc...

  • Article
  • Open Access
9 Citations
3,334 Views
10 Pages

Effect of N+ Implantation on Surface Characteristics of 316L Stainless Steels for Bipolar Plate in PEMFC

  • Yu-Sung Kim,
  • Dae-Wook Kim,
  • In-Sik Lee,
  • Sungook Yoon,
  • Daeil Kim,
  • Shinhee Jun and
  • Byung-Chul Cha

27 June 2020

Nitrogen was implanted into 316L stainless steel by plasma immersion ion implantation (PIII) for surface modification. Due to nitrogen implantation, the corrosion resistance and interfacial contact resistance (ICR) were improved compared to the bare...

  • Article
  • Open Access
15 Citations
3,840 Views
22 Pages

Characterization of Cell-Envelope Proteinases from Two Lacticaseibacillus casei Strains Isolated from Parmigiano Reggiano Cheese

  • Lisa Solieri,
  • Laura Sola,
  • Amanda Vaccalluzzo,
  • Cinzia Lucia Randazzo,
  • Serena Martini and
  • Davide Tagliazucchi

14 January 2022

In the present work, two cell-envelope proteinases (CEPs) from Lacticaseibacillus casei strains PRA205 and 2006 were characterized at both the biochemical and genetic levels. The genomes of both L. casei strains included two putative CEPs genes prtP2...

  • Review
  • Open Access
4 Citations
3,365 Views
38 Pages

9 October 2025

Due to their low elasticity modulus, significant fatigue strength, and good formability, titanium and titanium alloys have shown a continuous growth trend in various fields of application. However, the passivation film on the surface of titanium and...

  • Article
  • Open Access
18 Citations
6,619 Views
28 Pages

A Meta-Analysis of the Protein Components in Rattlesnake Venom

  • Anant Deshwal,
  • Phuc Phan,
  • Jyotishka Datta,
  • Ragupathy Kannan and
  • Suresh Kumar Thallapuranam

23 May 2021

The specificity and potency of venom components give them a unique advantage in developing various pharmaceutical drugs. Though venom is a cocktail of proteins, rarely are the synergy and association between various venom components studied. Understa...

  • Article
  • Open Access
16 Citations
3,948 Views
18 Pages

12 June 2018

Design annual runoff is a classical issue in traditional univariate hydrological frequency analysis (HFA). We developed a multivariate HFA approach for designs for a study region covering the confluence of two streams. HFA relies on the assumption th...

  • Article
  • Open Access
31 Citations
6,361 Views
25 Pages

Size Matters: An Evaluation of the Molecular Basis of Ontogenetic Modifications in the Composition of Bothrops jararacussu Snake Venom

  • Luciana A. Freitas-de-Sousa,
  • Pedro G. Nachtigall,
  • José A. Portes-Junior,
  • Matthew L. Holding,
  • Gunnar S. Nystrom,
  • Schyler A. Ellsworth,
  • Noranathan C. Guimarães,
  • Emilly Tioyama,
  • Flora Ortiz and
  • Ana M. Moura-da-Silva
  • + 5 authors

11 December 2020

Ontogenetic changes in venom composition have been described in Bothrops snakes, but only a few studies have attempted to identify the targeted paralogues or the molecular mechanisms involved in modifications of gene expression during ontogeny. In th...

  • Article
  • Open Access
1 Citations
2,646 Views
13 Pages

Generation of a Biotin-Tagged Dual-Display Phage

  • Laura Maria De Plano,
  • Salvatore Oddo,
  • David Bikard,
  • Antonella Caccamo and
  • Sabrina Conoci

14 October 2024

Phage display is widely used in biomedical research. One of the great advantages of phage display is the specificity of the connection of a foreign peptide exposed outside the capsid to the intended target. Secondary detection systems, which are ofte...

  • Article
  • Open Access
2,581 Views
20 Pages

28 June 2025

Snakebite envenoming is a neglected tropical disease that causes substantial mortality and morbidity globally. The puff adder (Bitis arietans) and saw-scaled viper (Echis romani) have cytotoxic venoms that cause permanent injury via dermonecrosis aro...

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