315 Results Found

Motivation: PubMed is a primary source of biomedical information comprising search tool function and the biomedical literature from MEDLINE which is the US National Library of Medicine premier bibliographic database, life science journals and online...

Metabolomics can help identify candidate biomarker metabolites whose levels are altered in response to disease development or drug administration. However, assessment of the underlying molecular mechanism is challenging considering it depends on the...

There are variations in the values reported for aerosol drug delivery across in vitro experiments throughout the published literature, and often with the same devices or similar experimental setups. Factors contributing to this variability include, b...

More than 7000 rare diseases affect over 400 million people, posing significant challenges for medical research and healthcare. The integration of precision medicine with artificial intelligence offers promising solutions. This work introduces a clas...

Introduction: There is growing interest in the development and application of standardized imaging criteria (SIC), to minimize variability and improve the reproducibility of image interpretation in head and neck squamous cell carcinoma (HNSCC). Metho...

Background: The application of Health Information Technologies (HITs) can be an effective way to advance medical research and health services provision. The two-fold objective of this work is to: (i) identify and review state-of-the-art HITs that fac...

Backgrounds and Objective: Facial palsy is a complex pathophysiological condition affecting the personal and professional lives of the involved patients. Sudden muscle weakness or paralysis needs to be rehabilitated to recover a symmetric and express...

To analyze the effect of a groove cross-sectional shape on disc filters, a head loss analysis and filtration performance test were conducted using disc filters with different groove shapes (semi-elliptical- and trapezoidal-shaped grooves). Furthermor...

For the investigation of the cavitation of non-jammed submersible grinder pumps, a GSP-22 model pump was numerically simulated based on CFX. ICEM-CFD was applied to a structured mesh for the flow components. Pump performance and the influence of the...

Shape modeling is a dynamic area in computer graphics with significant applications in computer-aided design, animation, architecture, and entertainment. Virtual sculpting, a key paradigm in free-form modeling, has traditionally been performed on des...

In biomechanics and orthopedics, finite element modelling allows simulating complex problems, and in the last few years, it has been widely used in many applications, also in the field of biomechanics and biotribology. As is known, one crucial point...

The current paper focuses on the assessment of radial mesh influence on the description of the transient event obtained by an axisymmetric model. The objective is to reduce computational effort while accurately calculating hydraulic transients in smo...

Determining the water table shape and position in unconfined aquifers is fundamental to many groundwater flow assessment studies. The commonly used industry-standard fixed mesh models, contrary to popular belief, do not provide an accurate descriptio...

This study presents a hybrid approach for simulating flow and advective transport dynamics in fractured rocks. The developed hybrid domain (HD) model uses the two-dimensional (2D) triangular mesh for fractures and tetrahedral mesh for the three-dimen...

Background: orbital floor fractures have not been reconstructed using magnesium biomaterials. Methods: To test technical feasibility, ex vivo caprine and ovine heads (n = 5) were used. Head tissues were harvested from pubescent animals (n = 5; mean a...

In the present study, an erosion analysis of an industrial pump’s casing and impeller blades has been performed computationally. Effects of various critical parameters, i.e., the concentration and size of solid particles, exit pressure head, and cavi...

The purpose of the present study was to examine the impact of scanning strategy on trueness and precision of the impression acquired from an intraoral scanner. Fifteen complete-arch, mandibular, post-orthodontic treatment casts were scanned with a la...

In this paper, numerical simulations of the EN 12767 test procedure for a vehicle–lighting pole crash are presented. A representative soil–vehicle–lighting pole model is first developed. The Geo Metro vehicle model is used, and significant attention...

Objective: To evaluate the development of the craniofacial region in healthy infants and analyze the asymmetry pattern in the first year of life. Methods: The participants were grouped by sex and age (1, 2, 4, 6, 9, and 12 months) to receive three-di...

In the grinding process, acceleration signals in both the time and frequency domains are valuable for monitoring and controlling vibration patterns, as factors such as rotational speed and the grinding head design significantly influence machining qu...

Analysis of a PAT modeling is presented for application in water pipe systems as an interesting and promising energy converter to improve the system energy efficiency. The study is focused on the use of a Computational Fluid Dynamics (CFD) model in c...

Trash racks are usually composed of an array of bars installed in a hydropower scheme to safeguard the turbines by collecting water-borne detritus. However, current design approaches for the design of trash racks focus on structural criteria. A littl...

The trans-media aircraft water entry process generates strong slamming loads that will seriously affect the stability and safety of the aircraft. To address this problem, we design a fixed-wing aircraft configuration and employ numerical simulations...

Clustering methods are promising tools for ensuring the network scalability and maintainability of large-scale flying ad hoc networks (FANETs). However, due to the high mobility and limited energy resources of unmanned aerial vehicles (UAVs), it is d...

The number of random fields required to capture the spatial variability of soil properties and their impact on the performance of geotechnical systems is often varied. However, the number of random fields required to obtain higher-order statistical m...

Semantic urban 3D meshes obtained by deep learning networks have been widely applied in urban analytics. Typically, a large amount of labeled samples are required to train a deep learning network to extract discriminative features for the semantic se...

Myocardial ischemia is the major cause of death worldwide, and reperfusion is the standard intervention for myocardial ischemia. However, reperfusion may cause additional damage, known as myocardial reperfusion injury, for which there is still no eff...

Background: Several natural products have been reported to elicit beneficial effects against neurodegenerative disorders due to their vitamin E contents. However, the neuroprotective efficacy of palm oil or its tocotrienol-rich fraction (TRF) from th...

With the intensification of the oil crisis, research on drag reduction technologies has gained increasing momentum. In tidal environments, the drag reduction effectiveness of conventional methods, such as bionic non-smooth surfaces, super-hydrophobic...

The Microsoft HoloLens is a head-worn mobile augmented reality device that is capable of mapping its direct environment in real-time as triangle meshes and localize itself within these three-dimensional meshes simultaneously. The device is equipped w...

Over the years, Computational Fluid Dynamics (CFD) has been an integral part of most pump design processes. Unfortunately, as calculation schemes and flow investigations become more complicated, the cost of conducting numerical simulations also becom...

Generally, the operation of the horizontally-framed miter gate in a ship lock should consider the effects of hydrodynamic resistance. If over-filling or over-emptying exists and the miter gate opens with reverse head, the hydrodynamic resistance will...

Existing 3D semantic scene reconstruction methods utilize the same set of features extracted from deep learning networks for both 3D semantic estimation and geometry reconstruction, ignoring the differing requirements of semantic segmentation and geo...

Double-regulated Kaplan turbines with adjustable guide vanes and runner blades offer a high degree of flexibility and good efficiency for a wide range of operating points. However, this also leads to a complex geometry and flow guidance with, for exa...

Type 2 diabetes mellitus (T2DM) is a public health condition where environmental and genetic factors can intersect through hydroxymethylation. It was unclear which blood DNA regions were hydroxymethylated in human T2DM development. We aimed to identi...

Background: Thyroid storm is a rare but life-threatening emergency that prompts urgent intervention to halt its potentially disastrous outcomes. There is not much literature available on thyroid storm in head neck trauma and non-thyroid/parathyroid h...

Filters are essential components for maintaining the stability of drip irrigation systems, effectively reducing the risk of clogging. However, when applied to slurry drip irrigation systems, the complexity of slurry water quality makes it unclear how...

In certain mining areas, bauxite ore exhibits high and uneven hardness, causing frequent overloads in the cutting heads of bauxite mining equipment and challenging the dynamic performance and reliability of its gear transmission system. To investigat...

A large number of solid particles and fibrous impurities are always entrained in the fluid transported by a sewage pump, which can easily lead to the blockage of the sewage pump. In view of this, CFD–DEM simulations were conducted in this paper...

This work proposed a base method for automated assessment of Small Hydro-Power (SHP) potential for a run-of-river (RoR) scheme using geographic information systems (GIS). The hydro-power potential (HP) was represented through a comprehensive methodol...

Background: Three-dimensional facial anthropometry is increasingly used in orthodontics and orthognathic surgery. Conventional face scanning systems such as Vectra^® and 3dMD^® are well validated but remain costly and technically demanding. The...

This paper presents a study of run-up/overtopping over a smooth impermeable dike with promenade using 2D and 3D mesh-based and mesh-free numerical models and results from 2D physical modelling for strong energetic incident waves. These waves induce p...

This paper presents a numerical study of the depth tracking control for an underwater towed system under wave–ship interference condition. To overcome the laminations of ignoring the hydrodynamic factors and wave–ship interference in the existing sim...

In this study, the skull bone thicknesses of 150 patients ranging in age from 0 to 72 years were calculated using a novel approach (thermal analysis), and thickness changes were analyzed. Unlike conventional thickness calculation approaches (Beam Pro...

In this paper, we introduce a multi-label lazy learning approach to deal with automatic semantic indexing in large document collections in the presence of complex and structured label vocabularies with high inter-label correlation. The proposed metho...

Peripheral neuropathy (PN) is frequently observed in systemic rheumatic diseases and is a challenge in clinical practice. We aimed to review the evidence on the subject and proposed a comprehensive approach to these patients, facilitating diagnosis a...

In landmark-based analyses of size and shape variation and covariation among biological structures, regions lacking clearly identifiable homologous landmarks are commonly described by semilandmarks. Different algorithms may be used to apply semilandm...

The high price of purpose-made turbines always represents an active challenge when utilizing pico- and micro-hydropower resources. Pumps as turbines (PATs) are a promising option to solve the problem. However, the selection of a suitable pump for a s...

Introduction: Head and neck bone reconstruction is a challenging surgical scenario. Although several strategies have been described in the literature, bone free flaps (BFFs) have become the preferred technique for large defects. Revascularized free p...

Scientific knowledge is being accumulated in the biomedical literature at an unprecedented pace. The most widely used database with biomedicine-related article abstracts, PubMed, currently contains more than 36 million entries. Users performing searc...