Genome-wide association studies and experimental mouse models implicate the MIB1 and GATA6 genes in congenital heart disease (CHD). Their close physical proximity and conserved synteny suggest that these two genes might be involved in analogous cardi...
Outbreaks of 2-methylisoborneol (2-MIB) contamination in drinking water sources cause inconvenient odor issues in the water distribution system. In this study, microscopy-based isolation with physiological and molecular phylogenetic characterization...
Left ventricular noncompaction (LVNC) is a structural abnormality of the left ventricle, usually described as an isolated condition, or sometimes associated with other structural cardiac diseases. LVNC is generally asymptomatic, although it may prese...
Centriolar satellites are non-membrane cytoplasmic granules that deliver proteins to centrosome during centrosome biogenesis and ciliogenesis. Centriolar satellites are highly dynamic during cell cycle or ciliogenesis and how they are regulated remai...
Because of the substantial progress in quantum computing technology, the safety of traditional cryptologic schemes is facing serious challenges. In this study, we explore the quantum safety of the lightweight cipher MIBS and propose quantum key-recov...
The MIB-1 index is an essential predictor of progression-free-survival (PFS) in meningioma. To date, the MIB-1 index is not available in preoperative treatment planning. A preoperative score estimating the MIB-1 index in patients with intracranial me...
The MIB-1 index is an important risk factor for progression-free survival (PFS) in pituitary adenoma (PA). Preoperatively, the MIB-1 index is not available in the decision-making process. A preoperative method regarding MIB-1 index estimation in PA h...
2-methylisoborneol (2-MIB) is a common taste and odor compound caused by off-flavor secondary metabolites, which represents one of the greatest challenges for drinking water utilities worldwide. A TiO2-coated activated carbon (TiO2/PAC) has been synt...
2-methylisoborneol (MIB, d = 0.6 nm) and dimethyl disulfide (DMDS, d = 0.7 nm) produced by algal metabolism are the main olfactory contaminants of drinking water. Activated carbon (AC) adsorption is an effective method to remove MIB/DMDS, yet critica...
Background/Objectives: Hallux valgus, or a bunion, is a prevalent foot deformity associated with pain, limited mobility, and reduced quality of life. Surgical treatments include minimally invasive and traditional open techniques, but the optimal appr...
Although meningiomas are mainly non-aggressive and slow-growing tumors, there is a remarkable recurrence rate in a long-term follow-up. Proliferative activity and progression-free survival (PFS) differs significantly among the anatomic location of me...
Abducens nerve palsy is a severe dysfunction after petroclival meningioma (PC MNG) surgery. The objective of this investigation was to analyze abducens nerve outcomes in patients who underwent the retrosigmoid approach in relation to the MIB-1 index....
Bioindication is a key tool for monitoring habitat quality and ecosystem dynamics under increasing anthropogenic pressure. Among model organisms, ground beetles (Coleoptera: Carabidae) play a particularly important role, and one of the widely applied...
Due to climate change, population growth, industrialization, urbanization, and water contamination, it is becoming more difficult to secure and supply clean and safe drinking water. One of the challenges many water utilities often face is the taste a...
16 March 2020
The volatile metabolite, 2-Methylisoborneol (2-MIB) produced by cyanobacterial species, causes odor and taste problems in freshwater systems. However, simple identification of cyanobacteria that produce such off-flavors may be insufficient to establi...
Notch signaling is a conserved pathway crucial for nervous system development. Disruptions in this pathway are linked to neurodevelopmental disorders, neurodegenerative diseases, and brain tumors. Hairy/E(spl) (HES) genes, major downstream targets of...
One controversial issue in pituitary pathology is the simultaneous proliferation of PitNETs and endothelial cells. No previous studies have compared the MIB1 Labeling Index (MIB1 LI) of PitNETs and stromal endothelial compartments and its connection...
2-methylisoborneol (2-MIB), produced by cyanobacteria in water systems, has a musty odor and causes discomfort in humans. Extra costs are incurred when removing 2-MIB from water. The growth of 2-MIB-producing cyanobacteria, as well as the occurrence...
The MIB-1 index was demonstrated to be significantly correlated to meningioma recurrence. However, to date, the relationship of the intraindividual course of the MIB-1 index and the growth fraction, respectively, to clinical tumor recurrence has not...
Taste and odor (T&O) compounds in freshwater are frequently produced by certain cyanobacteria; however, their occurrence remains difficult to predict. This study examined the temporal and spatial variations in the mibC gene, which encodes a criti...
Geosmin and 2-methylisoborneol (MIB) are the most common causes of unpleasant odours in drinking water. A method was proposed to detect and recognise these compounds in water and determine their concentrations. The method utilises commercial solid-st...
This study investigated the seasonal and spatial dynamics of off-flavour compounds—geosmin and 2-methylisoborneol (2-MIB)—in an intensive rainbow trout (Oncorhynchus mykiss) aquaculture system for human consumption in western Spain. Weekl...
Cyanobacteria can exist in water resources and produce odorants. 2-Methylisoborneol (2-MIB) and geosmin are the main odorant compounds affecting the drinking water quality in reservoirs. In this study, encoding genes 2-MIB (mic, monoterpene cyclase)...
Harmful cyanobacterial blooms are continuously formed in water systems such as reservoirs and lakes around the world. Geosmin and 2-methylisoborneol (2-MIB) produced by some species of cyanobacteria have caused odor problems in the drinking water of...
The matched interface and boundary method (MIB) and ghost fluid method (GFM) are two well-known methods for solving elliptic interface problems. Moreover, they can be coupled with efficient time advancing methods, such as the alternating direction im...
The demand for effective, economical, and sustainable anode materials for metal-ion batteries (MIBs) has increased significantly due to the rapid growth of energy storage technologies. Among various candidates, carbon-based materials have emerged as...
This study assessed natural variation in the macroinvertebrate assemblages (MIB) and water quality in one of the main basins with the largest agricultural activities in Chile (Aconcagua River Basin). We sampled throughout the annual cycle; nine sampl...
Medial sphenoid wing meningiomas (MSWM) are surgically challenging skull base tumors. Irregular tumor shapes are thought to be linked to histopathology. The present study aims to investigate the impact of tumor shape on postoperative functioning, pro...
The seasonal occurrence of algae blooms in surface waters remains a common problem, such as taste and odor (T&Os), the risk of disinfection by-products (DBPs), and disturbance to water treatment systems. The coagulation efficiency of plant-minera...
Emerging evidence emphasizes the prognostic importance of meningioma location. The present investigation evaluates whether progression-free survival (PFS), proliferative potential, World Health Organization (WHO) grades, and inflammatory burden diffe...
CARD19 is a mitochondrial protein of unknown function. While CARD19 was originally reported to regulate TCR-dependent NF-κB activation via interaction with BCL10, this function is not recapitulated ex vivo in primary murine CD8+ T cells. Here,...
The goal of this study was to examine the changes in chemical parameters, major volatile compounds, and sensory aspects in farm-raised hybrid catfish (i.e., dorsal, lateral line and ventral muscles) during a 15-day period of refrigerated storage. Tri...
Geosmin and 2-methylisoborneol (2-MIB) are secondary bacterial metabolites that create an earthy-musty taste and odour (T&O) in drinking water. Both compounds exhibit low odour thresholds and are the leading causes of customer complaints to water...
High concentrations of 2-methylisoborneol (2-MIB) were reported during winter in the Paldang reservoir and North Han River, South Korea. The causes of the unusual taste and odor problems in the regulated river-reservoir system were not understood; ho...
Background/Objectives: This retrospective observational study aimed to investigate the perioperative outcome in Malignant Peripheral Nerve Sheath Tumors (MPNSTs) with and without relation to Neurofibromatosis Type 1 (NF1) and to detect possible influ...
Background/Objectives: To evaluate the prognostic impact of immunohistochemical ki-67 staining analysis regarding lymph node involvement and survival data (overall/progression-free survival) in squamous cell carcinoma of the vulva. Methods: A systema...
(1) Background: Whole Exome Sequencing of patients with thoracic aortic aneurysm often identifies “Variants of Uncertain Significance” (VUS), leading to uncertainty in clinical management. We assess a novel mechanism for potential routine...
Thoracic aortic aneurysms (TAA) consist of abnormal dilation or the widening of a portion of the ascending aorta, due to weakness or destructuring of the walls of the vessel and are potentially lethal. The congenital bicuspid aortic valve (BAV) is co...
This study sought to explore the existence and clinical significance of intratumoral heterogeneity of proliferative potential in vestibular schwannoma (VS). Rapid intraoperative flow cytometry was utilized with raw samples to measure the proliferativ...
Simulating the acoustic field excited by pulse sound sources holds significant practical value in computational ocean acoustics. Two primary methods exist for modeling underwater acoustic propagation in the time domain: the Fourier synthesis techniqu...
Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic a...
2-Methylisoborneol (2-MIB) is a common off-flavor metabolite, and it has a very low odor threshold value. 2-MIB is produced by a variety of cyanobacteria and heterotrophic bacteria. In this study, Dolichospermum spiroides (Anabaena spiroides, FACHB 4...
The presence of the odorant 2-methylisoborneol (2-MIB) in drinking water sources is undesirable. Although 2-MIB production is known to be influenced by temperature, its regulation at the gene level and its relationship with Chlorophyll-a (Chl-a) at d...
18 May 2018
2-Methylisoborneol (2-MIB) is one of the most commonly observed taste and odor (T&O) compounds present in drinking water sources. As it is biodegradable, a preservation agent, typically mercury chloride, is needed if the water is not analyzed rig...
With increasingly severe cyanobacterial blooms, the overflow of off-flavor compounds represented by geosmin (GSM) and 2-methylisoborneol (2-MIB) is becoming a global water quality issue. The UV photo-electrochemical process is considered an environme...
Taste and odor (T&O) compounds have emerged as crucial parameters for assessing water quality. Therefore, identifying effective methodologies for the removal of these compounds is imperative. In this study, an effective approach utilizing laccase...
30 May 2019
We investigated the adsorption characteristics of geosmin and 2-methylisoborneol (MIB) on graphene oxide (GO) in the absence and presence of natural organic matter (NOM). The graphene oxide had fast adsorption kinetics for both compounds because of i...
(1) Dental caries, periodontitis, or peri-implantitis are commensal infections related to oral biofilm former bacteria. Likewise, magnesium oxide nanoparticles (MgO-NPs) were studied to introduce them to the antibacterial properties of a few microorg...
While rate distortion theory compresses data under a distortion constraint, information bottleneck (IB) generalizes rate distortion theory to learning problems by replacing a distortion constraint with a constraint of relevant information. In this wo...
The presence of 2-methylisoborneol (2-MIB) in water is a critical global concern due to its low threshold and resistance to conventional processes. In the present study, activated carbon/alginate (AC/alginate) composite beads were synthesized via ion...
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