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88,535 Results Found

  • Article
  • Open Access
7 Citations
3,494 Views
15 Pages

Vibrio parahaemolyticus Is Associated with Diarrhea Cases in Mexico, with a Dominance of Pandemic O3:K6 Clones

  • Nidia León-Sicairos,
  • Ricardo Zatarain-Lopez,
  • Uriel A. Angulo-Zamudio,
  • Jorge Velazquez-Roman,
  • Héctor Flores-Villaseñor,
  • Jesus J. Martinez-Garcia,
  • María Asunción Moreno-Pérez,
  • Alma Buelna-Romero,
  • Irma Hernández-Monroy and
  • Adrián Canizalez-Roman
  • + 3 authors

In the present study, we conducted surveillance of the V. parahaemolyticus strains present in clinical samples from six geographical regions of Mexico (22 states) from 2004 to 2011. The serotype dominance, virulence genes, presence of pandemic O3:K6...

  • Article
  • Open Access
25 Citations
4,607 Views
14 Pages

A Study on the Antimicrobial and Antibiofilm Peptide 1018-K6 as Potential Alternative to Antibiotics against Food-Pathogen Salmonella enterica

  • Rossella Festa,
  • Rosa Luisa Ambrosio,
  • Alexandre Lamas,
  • Lorena Gratino,
  • Gianna Palmieri,
  • Carlos Manuel Franco,
  • Alberto Cepeda and
  • Aniello Anastasio

14 June 2021

Antimicrobial resistance has become one of the major global public health concerns, and it is indispensable to search for alternatives to conventional antibiotics. Recently, antimicrobial peptides have received great attention because of their broad-...

  • Communication
  • Open Access
2 Citations
1,878 Views
10 Pages

Polyoxometalates have emerged as promising bactericidal agents. In the current study, the bactericidal activity of polyoxometalate K6[P2Mo18O62] against Escherichia coli (E. coli) O157:H7 and its possible underlying mechanisms were explored. The obta...

  • Article
  • Open Access
10 Citations
4,537 Views
19 Pages

Achieving fluency in arithmetic operations is vital if students are to develop mathematical creativity and critical thinking abilities. Nevertheless, a substantial body of literature has demonstrated that students are struggling to develop such skill...

  • Article
  • Open Access
30 Citations
3,735 Views
13 Pages

Extended k-Gamma and k-Beta Functions of Matrix Arguments

  • Ghazi S. Khammash,
  • Praveen Agarwal and
  • Junesang Choi

6 October 2020

Various k-special functions such as k-gamma function, k-beta function and k-hypergeometric functions have been introduced and investigated. Recently, the k-gamma function of a matrix argument and k-beta function of matrix arguments have been presente...

  • Review
  • Open Access
70 Citations
26,431 Views
13 Pages

Vitamin K2 Needs an RDI Separate from Vitamin K1

  • Asim Cengiz Akbulut,
  • Angelina Pavlic,
  • Ploingarm Petsophonsakul,
  • Maurice Halder,
  • Katarzyna Maresz,
  • Rafael Kramann and
  • Leon Schurgers

21 June 2020

Vitamin K and its essential role in coagulation (vitamin K [Koagulation]) have been well established and accepted the world over. Many countries have a Recommended Daily Intake (RDI) for vitamin K based on early research, and its necessary role in th...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,878 Views
9 Pages

Binary (k, k)-Designs

  • Todorka Alexandrova,
  • Peter Boyvalenkov and
  • Angel Dimitrov

30 October 2020

We introduce and investigate binary (k,k)-designs, a special case of T-designs. Our combinatorial interpretation relates (k,k)-designs to the binary orthogonal arrays. We derive a general linear programming bound and propose as a consequence a univer...

  • Article
  • Open Access
1 Citations
2,145 Views
15 Pages

On Hybrid Hyper k-Pell, k-Pell–Lucas, and Modified k-Pell Numbers

  • Elen Viviani Pereira Spreafico,
  • Paula Catarino and
  • Paulo Vasco

11 November 2023

Many different number systems have been the topic of research. One of the recently studied number systems is that of hybrid numbers, which are generalizations of other number systems. In this work, we introduce and study the hybrid hyper k-Pell, hybr...

  • Article
  • Open Access
2 Citations
1,902 Views
13 Pages

20 October 2021

Let R be a commutative ring with nonzero identity and k≥2 be a fixed integer. The k-zero-divisor hypergraph Hk(R) of R consists of the vertex set Z(R,k), the set of all k-zero-divisors of R, and the hyperedges of the form {a1,a2,a3,…,ak}, where a1,a2...

  • Review
  • Open Access
212 Citations
49,148 Views
15 Pages

Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease

  • Maurice Halder,
  • Ploingarm Petsophonsakul,
  • Asim Cengiz Akbulut,
  • Angelina Pavlic,
  • Frode Bohan,
  • Eric Anderson,
  • Katarzyna Maresz,
  • Rafael Kramann and
  • Leon Schurgers

19 February 2019

Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K can be present in various isoforms, distinguishable by two main structures, namely, phylloquinone (K1) and menaquinones (K2). The difference in structure betwe...

  • Feature Paper
  • Article
  • Open Access
5 Citations
2,439 Views
13 Pages

28 November 2022

The contribution of non-exchangeable soil K in the total K availability may be essential to K deficient soils; however, less attention has been paid so far for proposing soil tests that assess the bioavailable structural K that is solubilized by soil...

  • Review
  • Open Access
103 Citations
25,612 Views
13 Pages

Vitamin K and Osteoporosis

  • Maria Fusaro,
  • Giuseppe Cianciolo,
  • Maria Luisa Brandi,
  • Serge Ferrari,
  • Thomas L. Nickolas,
  • Giovanni Tripepi,
  • Mario Plebani,
  • Martina Zaninotto,
  • Giorgio Iervasi and
  • Angela M. Cheung
  • + 7 authors

25 November 2020

Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin K dependent proteins. Beyond its well-known effects on blood coagulation, it also exerts relevant effects on bone and the vascular system. In this review, we...

  • Article
  • Open Access
13 Citations
3,343 Views
26 Pages

k-Circle Formation and k-epf by Asynchronous Robots

  • Subhash Bhagat,
  • Bibhuti Das,
  • Abhinav Chakraborty and
  • Krishnendu Mukhopadhyaya

18 February 2021

For a given positive integer k, the k-circle formation problem asks a set of autonomous, asynchronous robots to form disjoint circles having k robots each at distinct locations, centered at a set of fixed points in the Euclidean plane. The robots are...

  • Article
  • Open Access
1,039 Views
22 Pages

11 October 2024

Inspired by prior research on fractional calculus, we introduce new fractional integral and derivative operators: the (ρ1,ρ2,k1,k2,φ)-proportional integral and the (ρ1,ρ2,k1,k2,φ)-proportional Hilfer fractional derivative. Num...

  • Article
  • Open Access
3 Citations
3,809 Views
6 Pages

10 September 2015

The isomorphism of Karoubi-Villamayor K-groups with smooth K-groups for monoid algebras over quasi stable locally convex algebras is established. We prove that the Quillen K-groups are isomorphic to smooth K-groups for monoid algebras over quasi-stab...

  • Article
  • Open Access
8 Citations
3,648 Views
14 Pages

Gal-2 Increases H3K4me3 and H3K9ac in Trophoblasts and Preeclampsia

  • Laura Hahn,
  • Sarah Meister,
  • Mareike Mannewitz,
  • Susanne Beyer,
  • Stefanie Corradini,
  • Uwe Hasbargen,
  • Sven Mahner,
  • Udo Jeschke,
  • Thomas Kolben and
  • Alexander Burges

Preeclampsia (PE) is a severe pregnancy disorder with a pathophysiology not yet completely understood and without curative therapy. The histone modifications H3K4me3 and H3K9ac, as well as galectin-2 (Gal-2), are known to be decreased in PE. To gain...

  • Article
  • Open Access
26 Citations
5,756 Views
10 Pages

2 July 2018

Potassium (K) is an essential macronutrient for maintaining crop productivity, but the economic benefit of K fertilizer often has been neglected. We collected a database from 60 maize field experimental sites in Northeast China between 2005 and 2012...

  • Article
  • Open Access
15 Citations
4,090 Views
10 Pages

Obesity has become a worldwide health problem, and many significant inflammatory markers have been associated with the risk of side effects of obesity and obesity-related diseases. After a normal diet or high-fat diet with high-fructose water (HFHF)...

  • Article
  • Open Access
11 Citations
2,651 Views
23 Pages

4 March 2020

The paper firstly establishes the so-called n-times iterated connected sum of a simple closed k-surface in Z 3 , denoted by C k n , k ∈ { 6 , 18 , 26 } . Secondly, for a simple closed 18-surface M S S 18 , we prov...

  • Article
  • Open Access
1 Citations
864 Views
14 Pages

Quantitative Investigation of the “K-Line Edge”, a Clustered K-Line (±) Group Derived from K-Line Assessment in Patients with Ossification of the Posterior Longitudinal Ligament

  • Kazuhiro Takeuchi,
  • Kazunori Hosotani,
  • Kensuke Shinohara,
  • Kentaro Yamane,
  • Shinichiro Takao,
  • Shinnosuke Nakahara and
  • Akiho Seki

17 October 2025

Background/Objectives: We investigated the impact of ossification of the posterior longitudinal ligament (OPLL) and cervical alignment on K-line assessment, proposed the K-line edge category for transitioning from K-line (+) to (−), and demonst...

  • Article
  • Open Access
88 Citations
6,913 Views
10 Pages

NS-k-NN: Neutrosophic Set-Based k-Nearest Neighbors Classifier

  • Yaman Akbulut,
  • Abdulkadir Sengur,
  • Yanhui Guo and
  • Florentin Smarandache

2 September 2017

k-nearest neighbors (k-NN), which is known to be a simple and efficient approach, is a non-parametric supervised classifier. It aims to determine the class label of an unknown sample by its k-nearest neighbors that are stored in a training set. The k...

  • Article
  • Open Access
334 Citations
40,993 Views
10 Pages

18 June 2019

Among many clustering algorithms, the K-means clustering algorithm is widely used because of its simple algorithm and fast convergence. However, the K-value of clustering needs to be given in advance and the choice of K-value directly affect the conv...

  • Article
  • Open Access
2 Citations
2,718 Views
14 Pages

3 November 2021

Given a connected graph G=(V(G),E(G)), a set S⊆V(G) is said to be a k-metric generator for G if any pair of different vertices in V(G) is distinguished by at least k elements of S. A metric generator of minimum cardinality among all k-metric generato...

  • Article
  • Open Access
11 Citations
3,864 Views
13 Pages

Acinetobacter baumannii K106 and K112: Two Structurally and Genetically Related 6-Deoxy-l-talose-Containing Capsular Polysaccharides

  • Anastasiya A. Kasimova,
  • Nikolay P. Arbatsky,
  • Jacob Tickner,
  • Johanna J. Kenyon,
  • Ruth M. Hall,
  • Michael M. Shneider,
  • Alina A. Dzhaparova,
  • Alexander S. Shashkov,
  • Alexander O. Chizhov and
  • Yuriy A. Knirel
  • + 1 author

Whole genome sequences of two Acinetobacter baumannii clinical isolates, 48-1789 and MAR24, revealed that they carry the KL106 and KL112 capsular polysaccharide (CPS) biosynthesis gene clusters, respectively, at the chromosomal K locus. The KL106 and...

  • Article
  • Open Access
13 Citations
3,455 Views
20 Pages

Our present investigation is mainly based on the k-hypergeometric functions which are constructed by making use of the Pochhammer k-symbol in Diaz et al. 2007, which are one of the vital generalizations of hypergeometric functions. In this study, we...

  • Article
  • Open Access
10 Citations
3,619 Views
16 Pages

19 April 2020

In this paper we carry out a reliability study of the consecutive-k1 and k2-out-of-n systems with independent and identically distributed components ordered in a line. More precisely, we obtain the generating function of the structure’s reliabi...

  • Article
  • Open Access
3 Citations
3,070 Views
16 Pages

14 January 2023

In this paper, we define the notion of almost repdigit as a positive integer whose digits are all equal except for at most one digit, and we search all terms of the k-generalized Fibonacci sequence which are almost repdigits. In particular, we find a...

  • Article
  • Open Access
11 Citations
5,051 Views
21 Pages

21 April 2019

Members of the PIP4K/PIP5K family of proteins, which generate the highly important secondary messenger phosphatidylinositol-4,5-bisphosphate, play central roles in regulating diverse signaling pathways. In eukaryotic organisms, multiple isozymes and...

  • Article
  • Open Access
14 Citations
4,114 Views
11 Pages

19 February 2019

In this paper, we expound on the hypergeometric series solutions for the second-order non-homogeneous k-hypergeometric differential equation with the polynomial term. The general solutions of this equation are obtained in the form of k-hypergeometric...

  • Review
  • Open Access
75 Citations
9,980 Views
17 Pages

11 February 2020

The mechanistic target of rapamycin (mTOR) is a master regulator of protein translation, metabolism, cell growth and proliferation. It forms two complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 is frequently deregulated in many cancers, incl...

  • Review
  • Open Access
6 Citations
2,016 Views
28 Pages

The Forgotten Tobamovirus Genes Encoding the 54 kDa Protein and the 4–6 kDa Proteins

  • Peter Palukaitis,
  • Masoud Akbarimotlagh,
  • Sajad Astaraki,
  • Masoud Shams-Bakhsh and
  • Ju-Yeon Yoon

28 October 2024

This article reviews the literature concerning the largely forgotten tobamovirus gene products for which no functions have been ascribed. One of these gene products is the 54 kDa protein, representing the RNA-dependent RNA polymerase segment of the 1...

  • Article
  • Open Access
5 Citations
2,436 Views
17 Pages

The Sweet Potato K+ Transporter IbHAK11 Regulates K+ Deficiency and High Salinity Stress Tolerance by Maintaining Positive Ion Homeostasis

  • Hong Zhu,
  • Jiayu Guo,
  • Tao Ma,
  • Shuyan Liu,
  • Yuanyuan Zhou,
  • Xue Yang,
  • Qiyan Li,
  • Kaiyue Yu,
  • Tongshuai Wang and
  • Jiongming Sui
  • + 3 authors

23 June 2023

The K+ transporter KT/HAK/KUP (K+ transporter/high-affinity K+/K+ uptake) family has a critical effect on K+ uptake and translocation in plants under different environmental conditions. However, the functional analysis of KT/HAK/KUP members in sweet...

  • Review
  • Open Access
31 Citations
11,790 Views
20 Pages

28 January 2015

Adenovirus makes extensive use of alternative RNA splicing to produce a complex set of spliced viral mRNAs. Studies aimed at characterizing the interactions between the virus and the host cell RNA splicing machinery have identified three viral protei...

  • Article
  • Open Access
5 Citations
2,418 Views
17 Pages

(L,M)-Fuzzy k-Pseudo Metric Space

  • Yu Zhong,
  • Xin Wu,
  • Alexander Šostak and
  • Fu-Gui Shi

2 April 2022

Recently, the notion of a classical k-metric, which make the triangle inequality to a more general axiom: d(x,z)≤k(d(x,y)+d(y,z)), has been presented and is applied in many fields. In this paper, the definitions of an (L,M)-fuzzy k-pseudo metric a...

  • Article
  • Open Access
34 Citations
8,989 Views
20 Pages

Improving Scalable K-Means++

  • Joonas Hämäläinen,
  • Tommi Kärkkäinen and
  • Tuomo Rossi

27 December 2020

Two new initialization methods for K-means clustering are proposed. Both proposals are based on applying a divide-and-conquer approach for the K-means‖ type of an initialization strategy. The second proposal also uses multiple lower-dimensional subsp...

  • Article
  • Open Access
12 Citations
4,222 Views
13 Pages

Dual Inhibition of H3K9me2 and H3K27me3 Promotes Tumor Cell Senescence without Triggering the Secretion of SASP

  • Na Zhang,
  • Mengjie Shang,
  • Hongxin Li,
  • Lan Wu,
  • Meichen Dong,
  • Baiqu Huang,
  • Jun Lu and
  • Yu Zhang

Chemotherapy remains the most common cancer treatment. Although chemotherapeutic drugs induce tumor cell senescence, they are often associated with post-therapy tumor recurrence by inducing the senescence-associated secretory phenotype (SASP). Theref...

  • Article
  • Open Access
8 Citations
4,243 Views
9 Pages

k-Rainbow Domination Number of P3Pn

  • Ying Wang,
  • Xinling Wu,
  • Nasrin Dehgardi,
  • Jafar Amjadi,
  • Rana Khoeilar and
  • Jia-Bao Liu

21 February 2019

Let k be a positive integer, and set [ k ] : = { 1 , 2 , … , k } . For a graph G, a k-rainbow dominating function (or kRDF) of G is a mapping f : V ( G ) → 2 [ k ] in such a way that, for any vertex v &isin...

  • Feature Paper
  • Article
  • Open Access
14 Citations
17,835 Views
13 Pages

18 July 2020

Vitamin K is a group of lipophilic molecules. Forms of vitamin K play an essential role in the activation of specific proteins involved in blood clotting cascade or bone metabolism. Another molecule belonging to the fat-soluble vitamins group that al...

  • Article
  • Open Access
1,417 Views
12 Pages

n-K-Increasing Aggregation Functions

  • Radko Mesiar,
  • Anna Kolesárová,
  • Adam Šeliga and
  • Radomír Halaš

21 November 2023

We introduce and discuss the concept of n-ary K-increasing fusion functions and n-ary K-increasing aggregation functions, K being a subset of the index set {1,…,n} indicating in which variables a considered function is increasing. It is also a...

  • Article
  • Open Access
10 Citations
2,189 Views
12 Pages

29 July 2021

The monotonicity of multi-valued operators serves as a guideline to prove the existence of the results in this article. This theory focuses on the existence of solutions without continuity and compactness conditions. We study these results for the (k...

  • Article
  • Open Access
25 Citations
7,016 Views
19 Pages

10 August 2022

Nowadays there is a large amount of information at our disposal, which is increasing day by day, and right now the question is not whether we have a method to process it, but which method is most effective, faster and best. When processing large data...

  • Article
  • Open Access
3 Citations
2,556 Views
23 Pages

In this study, we present our improved RANS results of the missile aerodynamic flow computation involving leading edge vortex separation. We have used our in-house tailored version of the open source finite volume solver FlowPsi. An ongoing study in...

  • Article
  • Open Access
4 Citations
2,780 Views
15 Pages

Pointwise k-Pseudo Metric Space

  • Yu Zhong,
  • Alexander Šostak and
  • Fu-Gui Shi

6 October 2021

In this paper, the concept of a k-(quasi) pseudo metric is generalized to the L-fuzzy case, called a pointwise k-(quasi) pseudo metric, which is considered to be a map d:J(LX)×J(LX)⟶[0,∞) satisfying some conditions. What is more, it is proved that th...

  • Article
  • Open Access
3 Citations
3,717 Views
17 Pages

Application of Neutrosophic Soft Sets to K-Algebras

  • Muhammad Akram,
  • Hina Gulzar,
  • Florentin Smarandache and
  • Said Broumi

12 November 2018

Neutrosophic sets and soft sets are two different mathematical tools for representing vagueness and uncertainty. We apply these models in combination to study vagueness and uncertainty in K-algebras. We introduce the notion of single-valued neutrosop...

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