The need for combining dissimilar materials is steadily increasing in the manufacturing industry, and the resulting products are expected to always have high performance. While there are various methods available for joining such material pairs, one...
Background: Dp71 is the most abundant dystrophin (DMD) gene product in the nervous system. Mutation in the Dp71 coding region is associated with cognitive disturbances in Duchenne muscular dystrophy (DMD) patients, but the function of dystrophin Dp71...
A deficiency in the shortest dystrophin-gene product, Dp71, is a pivotal aggravating factor for intellectual disabilities in Duchenne muscular dystrophy (DMD). Recent advances in preclinical research have achieved some success in compensating both mu...
The Dps protein is the major DNA-binding protein of prokaryotes, which protects DNA during starvation by forming a crystalline complex. The structure of such an intracellular DNA-Dps complex is still unknown. However, the phenomenon of a decrease in...
Dechlorane Plus (DP), an emerging type of persistent organic pollutant (POP), poses potential harmful effects on plants, animals, and humans alike, garnering increasing attention. Urban surface soil is easily accessible to urban residents, and its en...
This paper explores the prosodic patterns of complex DP structures in Xitsonga by looking at penultimate lengthening in DPs with marked and unmarked word orders of different types. We discuss the underlying syntactic structures and prosodic realizati...
Background: Dystrophin Dp71 is one of the isoforms produced by the DMD gene which is mutated in patients with Duchenne muscular dystrophy (DMD). Although Dp71 is expressed ubiquitously, it has not been detected in normal skeletal muscle. This study w...
The Duchenne muscular dystrophy (DMD) gene is one of the largest genes in the human genome. The gene exhibits a complex arrangement of seven alternative promoters, which drive the expression of three full length and four shorter isoforms. Dp116, the...
Differential privacy (DP) has become a de facto standard to achieve data privacy. However, the utility of DP solutions with the premise of privacy priority is often unacceptable in real-world applications. In this paper, we propose the best-effort di...
Gradual dehydration is one of the frequent lethal yet poorly understood stresses that bacterial cells constantly face in the environment when their micro ecotopes dry out, as well as in industrial processes. Bacteria successfully survive extreme desi...
Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease caused by deficiency in dystrophin, a protein product encoded by the DMD gene. Mitochondrial dysfunction is now attracting much attention as a central player in DMD pathology. Howeve...
Oil drilling and extraction platforms are currently being used in many offshore areas around the world. Whilst those operating in shallow seas are secured to the seabed, for deeper water operations, Dynamic Positioning (DP) is essential for the platf...
Sarcopenia is linked with an increased risk of falls, osteoporosis and mortality and is an increasing problem for healthcare systems. No satisfying biomarkers for sarcopenia diagnosis exist, connecting bone, fat and muscle. Matrix-GLA-protein (MGP) i...
Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony callus formation, and bone remodelling. Bone fractures represent a significant health problem, p...
Background/Objectives: Delays in bone healing and complications of remodeling constitute a major medical problem—particularly in older adults and patients with comorbidities. Current therapeutic approaches are based on strategies that promote b...
Dystrophin is a 427 kDa protein that stabilizes muscle cell membranes through interactions with the cytoskeleton and various membrane-associated proteins. Loss of dystrophin as in Duchenne muscular dystrophy (DMD) causes progressive skeletal muscle w...
Considering a class
In simple graphs, DP-coloring is a generalization of list coloring and thus many results of DP-coloring generalize those of list coloring. Xu and Wu proved that every planar graph without 5-cycles adjacent simultaneously to 3-cycles and 4-cycles is 4...
In response to adverse environmental factors, Escherichia coli cells actively produce Dps proteins which form ordered complexes (biocrystals) with bacterial DNA to protect the genome. The effect of biocrystallization has been described extensively in...
In order to resolve Borodin’s Conjecture, DP-coloring was introduced in 2017 to extend the concept of list coloring. In previous works, it is proved that every planar graph without 7-cycles and butterflies is DP-4-colorable. And any planar grap...
The power transformer is vital to the reliability of the power grid which is most commonly insulated with Kraft paper and immersed in mineral oil, among which the aged state of the paper is mainly correlated to the operating life of the transformer....
Two independent, complementary methods of structural analysis were used to elucidate the effect of divalent magnesium and iron cations on the structure of the protective Dps-DNA complex. Small-angle X-ray scattering (SAXS) and cryo-electron microscop...
Dps (DNA-binding protein from starved cells) is well known for the structural protection of bacterial DNA by the formation of highly ordered intracellular assemblies under stress conditions. Moreover, this ferritin-like protein can perform fast oxida...
In industrial control systems (ICSs), the PROFIBUS-DP (decentralized peripherals) protocol is widely used for communication between devices. Because PROFIBUS-DP is an unencrypted and insecure bus protocol, attackers can connect to the PROFIBUS-DP sys...
Prostaglandin D2 (PGD2) levels are high in the balding areas of human scalps, and PGD2 has been found to inhibit hair growth. It is known that the inhibition of the PGD2 receptor can promote hair growth by preventing hair follicles from entering the...
This study aims to simulate the stabilised stress-strain hysteresis loop of dual phase (DP) steel using micromechanical modelling. For this purpose, the investigation was conducted both experimentally and numerically. In the experimental part, the mi...
DP-coloring as a generalization of list coloring was introduced by Dvořák and Postle recently. In this paper, we prove that every planar graph in which the distance between 6
Due to its high strength and good plasticity, dual-phase (DP) steel is widely used for manufacturing the structural and reinforcement components of automobiles. Therefore, it is urgent to investigate the mechanical properties and microstructure varia...
Dual phase (DP) steels have high strength, while maintaining outstanding elongation capacities. This is possible using a well-controlled thermomechanical process that produces a perfect phase combination in the DP microstructures. However, automotive...
DP96R of African swine fever virus (ASFV), also known as uridine kinase (UK), encodes a virulence-associated protein. Previous studies have examined DP96R along with other genes in an effort to create live attenuated vaccines. While experiments in pi...
DP-coloring was introduced by Dvořák and Postle [J. Comb. Theory Ser. B 2018, 129, 38–54]. In this paper, we prove that every planar graph in which the 5
DNA-protecting proteins (Dps) are crucial for safeguarding chromosomal DNA in starved cells during the stationary phase under stressful conditions. In previous research, the two Dps proteins in Deinococcus geothermalis, Dgeo_0257 (Dps3) and Dgeo_0281...
Soft-tissue sarcomas (STS) are rare tumors whose oncogenesis remains unknown and for which no common therapeutic target has yet been identified. Analysis of 318 STS by CGH array evidenced a frequent deletion affecting the DMD gene (encoding dystrophi...
Resistance spot-welding of dissimilar metals, medium manganese TRIP steel 7Mn and DP590, is carried out. The effects of single-pulse welding parameters and a double-pulse-tempering current on the quality characteristic parameters and mechanical prope...
The Dps protein of Escherichia coli, which combines ferroxidase activity and the ability to bind DNA, is effectively used by bacteria to protect their genomes from damage. Both activities depend on the integrity of this multi-subunit protein, which h...
Prostaglandin D2 (PGD2) and prostaglandin D2 receptor 2 (DP2) is known to be an important factor in androgenetic alopecia (AGA). However, the effect of PGD2 in human dermal papilla cells (hDPCs) is not fully understood. The function of PGD2-induced e...
DNA-binding proteins from starved cells (Dps) are homododecameric nanocages, with N- and C-terminal tail extensions of variable length and amino acid composition. They accumulate iron in the form of a ferrihydrite mineral core and are capable of bind...
Dual Phase (DP) steel, composed of a ferrite matrix with dispersed islands of martensite, has become popular in auto-body car construction due to its outstanding mechanical properties (i.e., high strength and good ductility). DP steel softens at the...
Dystrophin Dp71 is the most abundant product of the Duchenne muscular dystrophy gene in the nervous system, and mutations impairing its function have been associated with the neurodevelopmental symptoms present in a third of DMD patients. Dp71 is req...
Di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT) exhibits significant antitumor activity. However, the mechanism of its pharmacological interaction with human serum albumin (HSA) and DNA remains poorly understood. Here, we aimed to eluci...
Galectin-3 (Gal-3) is a histologic marker of pancreatic cancer and a potential therapeutic target. This study aimed to characterize a novel sulfated agarose-derived oligosaccharide (DP9) from marine algae, Gracilaria lemaneiformis, evaluate its Gal-3...
In chronic hepatitis C (CHC), characterized by exhaustion of T-cell function, increased frequencies of double-positive (DP) (CD4+CD8+) cells are present in peripheral blood. We compared the exhaustion phenotype between DP and single positive (SP) T-c...
We report the structural, biochemical, and functional characterization of the product of gene PA0962 from Pseudomonas aeruginosa PAO1. The protein, termed Pa Dps, adopts the Dps subunit fold and oligomerizes into a nearly spherical 12-mer quaternary...
Dps proteins (DNA-binding proteins from starved cells) are multifunctional stress defense proteins from the Ferritin family expressed in Prokarya during starvation and/or acute oxidative stress. Besides shielding bacterial DNA through binding and con...
The integration of Virtual Reality (VR) and gamification techniques can be used to produce a fun virtual laboratory, including virtual spaces and educational content. This study developed a prototype for a virtual laboratory for powder-bed binder jet...
Rapid increase of intracellular synthesis of specific histone-like Dps protein that binds DNA to protect the genome against deleterious factors leads to in cellulo crystallization—one of the most curious processes in the area of life science at the m...
The edge DP-chromatic number of G, denoted by
In this pilot work, we are going to discuss several aspects concerning the Albanian language spoken in the Italian territory by immigrants of different generations. After an excursus on heritage languages in general, and Albanian as a heritage langua...
The multiple knapsack problem (0/1-mKP) is a valuable NP-hard problem involved in many science-and-engineering applications. In current research, there exist two main approaches: 1. the exact algorithms for the optimal solutions (i.e., branch-and-bou...
The strength of Ca2+ signaling is a hallmark of T cell activation, yet the role of Ca2+ homeostasis in developing T cells before expressing a mature T cell receptor is poorly understood. We aimed to unveil specific functions of the two plasma membran...
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