2025 December-2 - 157 articles
Background/Objectives: Arteriovenous malformations (AVMs) in the dominant temporo-parieto-occipital (TPO) junction of the brain are extremely rare and very difficult to remove surgically because this area includes multiple sensory and language networ...
Background: Bronchoscopic thermal ablation has emerged as a minimally invasive therapeutic option for managing pulmonary nodules in patients unsuitable for surgery or radiotherapy. Robotic-assisted bronchoscopy (RAB) offers enhanced stability and pre...
Background/Objectives: Artificial intelligence is revolutionizing healthcare across multiple areas, and periodontology is no exception to this emerging trend. This systematic study sought to rigorously assess the applicability and efficacy of artific...
Background/Objectives: Skin cancer is one of the most common diseases in the world, whose early and accurate detection can have a survival rate more than 90% while the chance of mortality is almost 80% in case of late diagnostics. Methods: A modified...
Background/Objectives: The delayed effects of organophosphate poisoning may manifest years after exposure, often masked by age-related diseases. The aim of this retrospective cohort study was to identify the biochemical “trace” that could...
Background/Objectives: SARS-CoV-2 infection has been linked to long-term neurological sequelae and structural brain alterations. Previous analyses, including baseline results from the COVIMMUNE-Clin study, showed brain volume reductions in COVID-19 p...
Background: Accurate quantification of visceral (VAT) and subcutaneous adipose tissue (SAT) is critical for understanding the cardiometabolic consequences of obstructive sleep apnea (OSA) and other chronic diseases. This study validates a customizati...
Introduction: Metabolomics-based phylogenetic profiling of prostate cancer (PCa) patients before and after stereotactic body radiation therapy (SBRT) can provide insight into the way in which treatment outcomes relate to the underlying physiology and...
Background/Objectives: Autism Spectrum Disorder (ASD) is a multifaceted neuropsychiatric condition characterized by early behavioral irregularities that often precede formal diagnosis. Timely and precise detection remains a major clinical challenge d...
Background/Objectives: To explore the predictive value of pericardial fat tissue (PFT) radiomics for left ventricular (LV) involvement and major adverse cardiac events (MACE) in arrhythmogenic right ventricular cardiomyopathy (ARVC). Methods: In this...
Background/Objectives: Sarcopenia, an underdiagnosed musculoskeletal disorder, is a serious cause of disability, poor quality of life, and healthcare costs in an increasingly elderly population. This study aimed to examine an ultrasound (US)-based, i...
Background: Youth football players experience rapid physical and biological changes while being exposed to high training loads, increasing performance demands and musculoskeletal injury risk. Current evaluations often analyze anthropometric, physiolo...
Background/Objectives: To evaluate the efficacy of balloon occlusion trans-arterial hepatic radioembolization with Yttrium-90 (b-TARE) in optimizing dose activity in patients with large or multifocal Hepatocellular Carcinoma (HCC) lesions with hetero...
Background/Objectives: Traditional medical image analysis methods often suffer from locality bias, limiting their ability to model long-range contextual relationships between spatially distributed anatomical structures. To overcome this challenge, th...
Background: Cancer poses a significant health risk to humans, with prostate cancer (PCa) being the second most common and deadly form among men, following lung cancer. Each year, it affects over a million individuals and presents substantial diagnost...
Background: Endothelial dysfunction plays a critical role in ischemic stroke. The Endothelial Activation and Stress Index (EASIX), calculated from creatinine, lactate dehydrogenase (LDH), and platelet levels, reflects endothelial injury. This study a...
Background/Objectives: Echocardiography is the reference standard for grading aortic stenosis (AS); however, it yields discordant severity estimates in up to 40% of patients. Multidetector computed tomography (MDCT)-derived methods for calculating ao...
Background: The uterocervical angle (UCA) is a promising ultrasound parameter for predicting preterm birth. Transvaginal ultrasound (TVUS) is the gold standard for cervical assessment; however, some patients may decline the procedure due to discomfor...
Background: Cervical cancer remains a major global health challenge, ranking fourth among malignancies in women, with an estimated 660,000 new cases and 350,000 deaths in 2022. Despite advances in vaccination and screening, incidence and mortality re...
Background/Objectives: The COVID-19 pandemic disrupted healthcare delivery worldwide, potentially delaying the diagnosis and treatment of oncologic diseases. This study aimed to evaluate the impact of the pandemic on stage at diagnosis, treatment all...
Background and Clinical Significance: Carcinosarcomas are highly aggressive tumors with both carcinomatous and sarcomatous components, typically arising from the female genital tract. Primary retroperitoneal carcinosarcomas are extremely rare, and th...
Background/Objectives: The extent of myocardial scar, visualized by late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR), is associated with mortality after acute myocardial infarction (MI). However, data on optimal cardiac b...
We report the case of a 53-year-old male patient who presented to the cardiology department with presyncope and atypical chest pain. The transthoracic echocardiography revealed a homogeneous hypoechoic mass measuring 2.5 × 5.7 cm at the level o...
Background and Clinical Significance: DNA methylation profiling has revolutionized the classification of central nervous system (CNS) tumors, providing insights into tumor prognosis, recurrence, and personalized treatments. However, a significant cha...
Background: Deep learning models have been used in the past for non-invasive liver fibrosis classification based on liver ultrasound scans. After numerous improvements in the network architectures, optimizers, and development of hybrid methods, the p...
Coronary artery bypass grafting (CABG) remains a cornerstone of treatment for patients with advanced or complex coronary artery disease, yet long-term success is influenced by graft patency, progression of native disease, and ventricular remodeling....
Background/Objectives: Population aging requires scalable approaches for early identification of cognitive decline, particularly mild cognitive impairment (MCI). Although the full 11-task BrainOK smartphone assessment showed excellent discrimination...
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Background/Objectives: Disorganization of the retinal inner layers (DRIL) is an important biomarker of diabetic macular edema (DME) that has a very strong association with visual acuity (VA) in patients. But the unavailability of annotated training d...
Background: In this hospital-wide evaluation of point-of-care testing (POCT) glucose meters, we introduced a residual safety margin (r) anchored to ISO 15197:2013 thresholds to quantify tolerance, move beyond binary pass/fail assessments, and enable...
Background: Accurate deformity classification and fusion-level planning are essential in adolescent idiopathic scoliosis (AIS) surgery and are traditionally guided by Cobb angle measurement and the Lenke system. Multimodal large language models (LLMs...
Background/Objectives: Accurate prognostication for patients with chronic critical illness (CCI) following brain injury remains challenging. Conventional scoring systems like the Acute Physiology and Chronic Health Evaluation II (APACHE II) and the N...
Background: Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology. Its clinical and histopathological diagnosis remains challenging due to the variability of its manifestations and the subjectivity involved in interpretation....
Background/Objectives: Tuberculosis remains a significant global health problem, particularly in resource-limited environments. Its mortality and spread can be considerably decreased by early and precise detection via chest X-ray imaging. This study...
Background: Low-grade endometrial stromal sarcoma (LG-ESS) is a rare uterine mesenchymal neoplasm characterized by indolent progression and strong hormonal responsiveness. Accurate diagnosis remains challenging due to its overlapping clinical, pathol...
Fat embolism syndrome (FES) is a clinical syndrome in which the obstruction of small blood vessels by fat emboli triggers a systemic inflammatory response, leading to organ dysfunction. Due to a lack of specific laboratory tests and physical examinat...
Background: Wolfram syndrome (WS) is an ultrarare neuroendocrine disorder caused by pathogenic variants in WFS1, frequently leading to progressive neurological, autonomic, and cognitive impairment. Anticipating neurological trajectories remains chall...
Background/Objectives: Since the invention of MRI, analytical methods for MRI data have continuously evolved. In recent years, the rapid development of artificial intelligence has transformed MRI data analysis—from functional MRI (fMRI) techniq...
Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a major cause of sudden death and a frequent finding in forensic practice. Correctly estimating thrombus age is crucial to reconstruct the temporal re...
In the original publication [...]
Glomerular filtration rate (GFR) is a key indicator of renal function. Traditional methods for GFR measurement have limitations including invasiveness, low spatial resolution, and lengthy protocols. Positron emission tomography (PET) radiotracers hav...
Background: Dynamic anterior stabilization (DAS) is a novel surgical technique for treating chronic anteroinferior glenohumeral instability. It presents an alternative to the currently used Bankart and Latarjet procedures, aiming to reduce associated...
Ultrasound is the primary, non-invasive imaging modality for evaluating renal anatomy and function in both acute and chronic settings. Familiarity with normal kidney morphology, cortical and parenchymal thickness, echogenicity, and Doppler parameters...
Background/Objectives: Artificial intelligence (AI) systems may enhance diagnostic accuracy in cone-beam computed tomography (CBCT) analysis. However, most validations focus on isolated tooth-level tasks rather than clinically meaningful full-mouth a...
Background: Liver cirrhosis is a chronic systemic disease with a prevalence of 1.3% worldwide. Malnutrition refers to an imbalance of essential nutrients or altered utilization, with a prevalence ranging from 5 to 92%. The aim of this study is to ass...
Background/Objectives: The aim of this study was to evaluate the cycle threshold (Ct) values of self-collected vaginal samples as a triage method to colposcopy for high-risk (hr) HPV-positive women. Methods: We analyzed data from GRECOSELF, a nationw...
Background/Objectives: Demodex mites are a common yet underdiagnosed cause of ocular surface diseases, including blepharitis and meibomian gland dysfunction (MGD). Traditional diagnosis via microscopic examination is labor-intensive and time-consumin...
Corneal diseases are a leading cause of blindness worldwide, although their early detection remains challenging due to subtle clinical presentations. Recent advances in artificial intelligence (AI) have shown promising diagnostic performance for ante...
Purposes: Beam hardening artifacts caused by dental implants remain one of the most significant limitations of cone-beam computed tomography (CBCT), often compromising the evaluation of peri-implant bone and potentially masking critical diagnostic fi...
Background: Nosocomial pneumonia (NP) is a significant cause of morbidity and mortality in intensive care unit (ICU) patients. Prior antibiotic use, polymicrobial infections, and the limitations of conventional microbiological methods often complicat...
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