Advances in Non-Invasive Diagnostic Technologies for Heart Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 694

Special Issue Editor


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Guest Editor
Cardiology Division, Miulli Hospital, 70021 Acquaviva delle Fonti, Italy
Interests: multimodal cardiac imaging; echocardiography; cardiac magnetic resonance

Special Issue Information

Dear Colleagues,

The use of non-invasive imaging techniques is undeniably one of the aspects that best characterize modern cardiology. With the implementation of percutaneous interventional procedures in the treatment of structural heart disease, and current advances in the management of chronic ischemic heart disease, metabolic storage diseases, and heart failure in clinical practice, imaging methods are required to provide increasingly sophisticated evaluation parameters, in order to adopt adequate therapeutic strategies and identify the patients best suited to undergo certain procedures. Therefore, clinicians in cardiac patient management cannot ignore the power of the complete and precise information provided by non-invasive diagnostic methods such as echocardiography, cardiac magnetic resonance imaging, cardiac CT, and nuclear cardiology, which can greatly facilitate correct diagnosis and adequate prognostic stratification.

With the expansion of imaging options and the paradigmatic shift to multimodality imaging, this Special Issue will explore and expand current research, to help identify areas of cardiovascular medicine where imaging can add value in improving diagnosis and the prediction of therapeutic benefits.

Dr. Dentamaro Ilaria
Guest Editor

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Keywords

  • transthoracic echocardiography
  • cardiac magnetic resonance
  • multimodality cardiovascular imaging
  • cardiac CT
  • transesophageal echocardiography
  • cardiovascular disease

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Published Papers (1 paper)

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Review

24 pages, 13910 KB  
Review
Multimodality Imaging in Apical Hypertrophic Cardiomyopathy: Can Echocardiography Learn from Cardiac Magnetic Resonance?
by Francesco Mangini, Massimo Grimaldi, Francesco Spinelli, Santo Dellegrottaglie, Antonio Di Monaco, Simona Quarta, Grazia Casavecchia, Matteo Gravina, Vincenzo Bellomo, Luca Sgarra, Sergio Suma, Gaetano Citarelli, Enrica Filograna, Robert W. W. Biederman and Roberto Calbi
Diagnostics 2025, 15(23), 3013; https://doi.org/10.3390/diagnostics15233013 - 26 Nov 2025
Viewed by 405
Abstract
Apical hypertrophic cardiomyopathy is a distinctive and often under-recognized variant of hypertrophic cardiomyopathy, characterized by predominant thickening of the apical segments of the left ventricle. Echocardiography and cardiac magnetic resonance imaging represent the two principal modalities for diagnosis and morphological assessment. While transthoracic [...] Read more.
Apical hypertrophic cardiomyopathy is a distinctive and often under-recognized variant of hypertrophic cardiomyopathy, characterized by predominant thickening of the apical segments of the left ventricle. Echocardiography and cardiac magnetic resonance imaging represent the two principal modalities for diagnosis and morphological assessment. While transthoracic echocardiography remains the first-line imaging technique, it may underestimate apical involvement, particularly when image foreshortening or poor endocardial/epicardial delineation occurs. Cardiac magnetic resonance has become the reference standard for defining apical morphology, quantifying hypertrophy, and characterizing myocardial tissue and perfusion. Beyond its diagnostic role, magnetic resonance serves as a research platform for the identification of new apical-centric criteria which, after appropriate validation, may be translated into echocardiographic practice. Echocardiography, however, retains unique strengths through its real-time evaluation of cardiac dynamics, ready-to-use approach to diastolic function assessment, and its ability to identify subtle apical or para-apical obstructive gradients that may raise the initial diagnostic suspicion. This review underscores the complementary roles of the two modalities and the multiple domains in which transthoracic echocardiography can derive substantial methodological and conceptual benefit from cardiac magnetic resonance imaging, both in imaging methodology and in the refinement of diagnostic evaluation. Full article
(This article belongs to the Special Issue Advances in Non-Invasive Diagnostic Technologies for Heart Diseases)
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