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2011	Diagnostics releases the inaugural issue and is published as a quarterly journal under the direction of the founding Editor-in-Chief, Prof. Dr. Andreas Kjaer.
2015	Diagnostics introduces a new type of article: Interesting Images. Diagnostics is covered by two important databases: PubMed and the Emerging Sources Citation Index (ESCI) of the Web of Science.
2016	Diagnostics announces the first Diagnostics Travel Award. Diagnostics sets up the following sections: Medical Imaging In Vitro Diagnostics Molecular Diagnosis
2018	Diagnostics publishes the first two Special Issue Books: Ovarian Cancer Screening and Diagnosis and Treatment of Thoracic Outlet Syndrome; Diagnostics Travel Award 2018 is announced.
2019	Diagnostics is covered by the Science Citation Index Expanded (SCIE) and receives its first impact factor: 2.489. Diagnostics is accepted for inclusion in Scopus. Diagnostics rearranges its sections as follows: Medical Imaging; Pathology and Molecular Diagnostics; Point-of-Care Diagnostics and Devices; Diagnostic Microbiology and Infectious Disease; Machine Learning and Artificial Intelligence in Diagnostics Diagnostics presents at the 2019 EANM Congress, Barcelona, Spain in October 2019
2020	Diagnostics changes to a monthly publication schedule.