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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nuclear Medicine and Molecular Imaging in Cancer Diagnosis, Therapy, and Treatment Assessment

edited by

Sara Harsini

submission deadline 30 Oct 2025 | 2 articles | Viewed by 2505 | Submission Open

Keywords: nuclear medicine; molecular imaging; PET/CT; theranostics; cancer diagnosis; treatment monitoring

(This special issue belongs to the Section Medical Imaging and Theranostics)

Deep Learning and Multimodal Feature Fusion for Advanced Medical Imaging Diagnosis

edited by

Sarmad Maqsood

and

Rytis Maskeliūnas

submission deadline 30 Oct 2025 | 1 articles | Viewed by 1206 | Submission Open

Keywords: deep learning; feature fusion; medical imaging; artificial intelligence in healthcare; diagnostic imaging; multimodal data integration; explainable AI; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Deep Learning in Medical Imaging: Challenges and Opportunities

edited by Morten Bo Søndergaard Svendsen

submission deadline 30 Oct 2025 | Viewed by 326 | Submission Open

Keywords: deep learning; artificial intelligence; medical imaging; endoscopy; image segmentation; medical image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Cardiothoracic Imaging: Recent Techniques and Applications in Diagnostics, Second Edition

edited by

Giacomo Sica

submission deadline 31 Oct 2025 | 11 articles | Viewed by 35771 | Submission Open

Keywords: emergency; cardiac imaging; thoracic imaging; aorta; MRI; CT; radiomics; artificial intelligence; ILD

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Machine Learning for Computer-Aided Diagnosis in Biomedical Imaging—2nd Edition

edited by

Farhan Akram

submission deadline 31 Oct 2025 | 15 articles | Viewed by 30939 | Submission Open

Keywords: cancer diagnosis; medical images; electronic health records; machine learning; deep learning; artificial intelligence; explainable AI models; multi-modal analysis; federated learning; CAD systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Cardiovascular Diseases

edited by Fabrizio Guarracini and Cristina Giannattasio

submission deadline 31 Oct 2025 | 21 articles | Viewed by 28358 | Submission Open

Keywords: cardiovascular disease; risk stratification; preventive cardiology; hypertension; dyslipidaemias; heart failure management; interventional cardiology; coronary artery disease; arrythmias

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning in Medical Image Segmentation and Diagnosis

edited by Rahib Abiyev

submission deadline 31 Oct 2025 | 11 articles | Viewed by 27542 | Submission Open

Keywords: deep learning in medical diagnosis; medical imaging and deep learning; data mining and deep learning; emerging deep learning techniques and diagnosis; deep learning for the classification of lesions and disease; deep learning for segmentation; denoising; and super resolution; deep learning for signal analysis; learning mechanisms in deep neural networks; ensemble learning; stacked networks; medical informatics; computer-assisted diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Assessment and Diagnosis of Cognitive Disorders

edited by

Elena Cecilia Rosca

submission deadline 31 Oct 2025 | 7 articles | Viewed by 23393 | Submission Open

Keywords: cognitive disorders; neurology; neuroimaging; biomarkers; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Oct 2025 | 13 articles | Viewed by 20647 | Submission Open

Keywords: diagnosis; precision medicine; predictive diagnostics; therapeutic strategies; biomarkers; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Ultrasound

edited by

Rute Santos

submission deadline 31 Oct 2025 | 12 articles | Viewed by 19425 | Submission Open

Keywords: quantitative ultrasound techniques; ultrasound tissue characterization; ultrasound-guided therapy or intervention; clinical applications of diagnostic ultrasound; ultrasound imaging processing; diagnostic ultrasound devices

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Heart Disease, 2nd Edition

edited by

Yuli Huang

submission deadline 31 Oct 2025 | 8 articles | Viewed by 16693 | Submission Open

Keywords: heart disease; coronary artery disease; arrhythmia; heart failure; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Vasculitis

edited by

Alicia Rodríguez-Pla

submission deadline 31 Oct 2025 | 8 articles | Viewed by 15997 | Submission Open

Keywords: vasculitis; advances; updates; management; treatment; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Sports Medicine

edited by

Luis Manuel Martínez Aranda

and

Jacobo Á. Rubio Arias

submission deadline 31 Oct 2025 | 6 articles | Viewed by 15833 | Submission Open

Keywords: diagnosis; sports injuries; injury frequency; ligaments; strain; tendon injuries; sport-related concussion; injury treatment; return to play; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Artificial Intelligence for Dentomaxillofacial Radiology—2nd Edition

edited by

Andre Luiz Ferreira Costa

Kaan Orhan

and

Sérgio Lúcio Pereira de Castro Lopes

submission deadline 31 Oct 2025 | 7 articles | Viewed by 13563 | Submission Open

Keywords: artificial intelligence; deep learning; dentomaxillofacial radiology; dentistry; diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis and Management of Head and Neck Disease

edited by

Cristiana Lo Nigro

submission deadline 31 Oct 2025 | 11 articles | Viewed by 13378 | Submission Open

Keywords: head and neck disease; oral and maxillofacial disease; throat cancer; thyroid disease; otolaryngology tumor

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis, Prognosis and Management of Hematologic Malignancies

edited by

Rossella Cacciola

Emma C. Cacciola

, Alessandra Romano and Alessandro Allegra

submission deadline 31 Oct 2025 | 6 articles | Viewed by 13323 | Submission Open

Keywords: leukemia; myeloproliferative neoplasms; myeloma; lymphoma

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis of Skin Disease

edited by

Gerardo Cazzato

submission deadline 31 Oct 2025 | 8 articles | Viewed by 13235 | Submission Open

Keywords: dermatology; dermatopathology; skin diseases; neoplastic diseases; inflammatory dermatopathology; CTCL; melanoma; squamous cell carcinoma; basal cell carcinoma; infectious diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Endoscopy in Diagnosis of Gastrointestinal Disorders—2nd Edition

edited by

Miguel Mascarenhas

submission deadline 31 Oct 2025 | 8 articles | Viewed by 12477 | Submission Open

Keywords: endoscopy; gastroenterology; coloproctology; digestive healthcare; artificial intelligence; digestive oncology; colonoscopy; capsule endoscopy; upper endoscopy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Fetal Cardiology

edited by Maciej Słodki

submission deadline 31 Oct 2025 | 5 articles | Viewed by 12127 | Submission Open

Keywords: fetal cardiology; echocardiography; medical imaging; diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Thyroid Disorders

edited by Vladan Zivaljevic

submission deadline 31 Oct 2025 | 5 articles | Viewed by 11554 | Submission Open

Keywords: thyroid disease management; diagnosis of thyroid disease; novel procedures; thyroid disorders; thyroid cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Coherence Tomography in Diagnosis of Ophthalmology Disease

edited by Ninel Z Gregori and Lisa C. Olmos de Koo

submission deadline 31 Oct 2025 | 7 articles | Viewed by 10109 | Submission Open

Keywords: adaptive optics; multimodal imaging; optical coherence tomography; retinal diseases; spectral-domain optical coherence tomography; swept-source optical copherence tomography

(This special issue belongs to the Section Biomedical Optics)

Diagnosis and Treatment of Pediatric Emergencies—2nd Edition

edited by

Katerina Kambouri

submission deadline 31 Oct 2025 | 4 articles | Viewed by 10016 | Submission Open

Keywords: pediatric emergency; diagnosis; pathology; management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Gynecological Oncology

edited by

Elena Bernad

and

Marius L. Craina

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9909 | Submission Open

Keywords: female genital neoplasms; breast neoplasms; screening; diagnosis; treatment; surgery; medical oncology; psycho-oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Pediatric Gastrointestinal Pathology

edited by Juan Putra

submission deadline 31 Oct 2025 | 6 articles | Viewed by 8533 | Submission Open

Keywords: inflammatory bowel disease; crohn disease; celiac disease; ulcerative colitis; vascular anomalies; eosinophilic esophagitis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Applications and Potential of Magnetic Resonance Spectroscopy

edited by Jimin Ren

submission deadline 31 Oct 2025 | 4 articles | Viewed by 8424 | Submission Open

Keywords: magnetic resonance spectroscopy; metabolite; lipids and phospholipids; brain; skeletal muscle

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Technologies in Orthopedic Surgery: Diagnosis and Management

edited by Giuseppe Salvatore

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8146 | Submission Open

Keywords: orthopedic surgery; orthopedic diagnosis; orthopedics; computer navigation and augmented reality; robotics; digital templating; 3D Printing; artificial intelligence; machine learning; deep learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk Factors for Frailty in Older Adults

edited by

Agustín Aibar Almazán

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7974 | Submission Open

Keywords: frailty; older adults; risk factors; chronic diseases; nutritional deficiencies; physical inactivity; social determinants; genetic predispositions; preventive measures; interventions; quality of life; health outcomes

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Thyroid Cancer

edited by

Kwangsoon Kim

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7560 | Submission Open

Keywords: thyroid cancer; diagnosis; surgery; recurrence; theranostics; prognosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2025

edited by

Paweł Gać

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7257 | Submission Open

Keywords: cardiovascular medicine; risk factors; heart and vascular biology; imaging diagnostics; electrocardiogram; biochemistry; toxicology; experimental medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Prognosis of Breast Cancer

edited by Domen Ribnikar

submission deadline 31 Oct 2025 | 5 articles | Viewed by 7145 | Submission Open

Keywords: breast cancer; gene expression profiling in breast cancer; cancer biomarkers; tumor biology; prediction; prognosis; systemic treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Musculoskeletal Imaging: From Diagnosis to Treatment

edited by

Chiara Martini

and Massimo De Filippo

submission deadline 31 Oct 2025 | 6 articles | Viewed by 6994 | Submission Open

Keywords: musculoskeletal imaging; artificial intelligence; bone imaging; musculoskeletal ultrasound; diagnosis; machine learning algorithms

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Clinical Decision Support—2nd Edition

edited by

Qingqing Mao

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5817 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support; predictive modeling; patient monitoring; diagnostic support; treatment recommendation; safety and privacy

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Perspectives in Cardiac Imaging

edited by

George Koulaouzidis

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5781 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiac magnetic resonance imaging; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Dermatology and Venereology: Diagnosis and Management

edited by

Giulia Ciccarese

submission deadline 31 Oct 2025 | 4 articles | Viewed by 5737 | Submission Open

Keywords: skin infections; sexually transmitted infections; human papillomavirus; syphilis; pityriasis rosea; exanthem

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advances in Machine Learning for Medical Image Processing and Analysis

edited by Wei Shao

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4808 | Submission Open

Keywords: machine learning; medical image processing; diagnostic accuracy; healthcare; algorithms

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

3rd Edition: AI/ML-Based Medical Image Processing and Analysis

edited by

Ghazanfar Latif

and

Jaafar Alghazo

submission deadline 31 Oct 2025 | 5 articles | Viewed by 4785 | Submission Open

Keywords: machine learning; artificial intelligence; medical imaging; medical diagnosis; medical; magnetic resonance imaging (MRI); CT scan; X-ray; computer tomography; imaging techniques; medical conditions; convolutional neural networks; deep learning; transfer learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Optimizing Personalized Radiation Dose in Computed Tomography: Justification and Diagnostic Reference Levels

edited by

Mohamed Abuzaid

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4690 | Submission Open

Keywords: computed tomography; personalized radiation dose; computed tomography optimization; diagnostic reference levels; radiation dose justification; CT dose management; AI applications in dose management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Generative AI and Deep Learning in Medical Diagnostics

edited by

Steven L. Fernandes

submission deadline 31 Oct 2025 | 1 articles | Viewed by 4496 | Submission Open

Keywords: generative AI; medical diagnostics; medical imaging processing and analysis; deep learning; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Prognosis of Gynecological and Obstetric Diseases

edited by

Giuseppe Gullo

and Valentina Billone

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4342 | Submission Open

Keywords: diagnosis; prognosis; gynecological and obstetric diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Musculoskeletal Diseases

edited by Kavithalakshmi Sataranatarajan

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4296 | Submission Open

Keywords: musculoskeletal diseases; pathological diagnosis; high-resolution imaging; muscle biopsy; biomarkers; genetic testing

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

PET/CT Diagnostics and Theranostics

edited by

Salvatore Annunziata

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4042 | Submission Open

Keywords: PET/CT; diagnostics; theranostics; medical imaging; development

(This special issue belongs to the Section Medical Imaging and Theranostics)

Challenges in Monitoring and Diagnosis in Medical Sciences

edited by

Mihaela Badea

and

Laura Gaman

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3377 | Submission Open

Keywords: diagnostic; monitoring; medical sciences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Thoracic Diseases

edited by

Ke-Cheng Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3198 | Submission Open

Keywords: thoracic diseases; lung; diagnosis; treatment; lung tumor; thoracoscopy; biomarker; prognosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

AI-Powered Clinical Diagnosis and Decision-Support Systems

edited by

Hung-Sheng Shang

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2909 | Submission Open

Keywords: artificial intelligence; clinical decision support system; medical diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Applications of Quantitative MRI in Neurodegenerative Disorders and Peripheral Neuropathies

edited by

Yongsheng Chen

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2597 | Submission Open

Keywords: quantitative MRI; neurodegeneration; iron deposition; demyelination; remyelination; Parkinson’ s disease; multiple sclerosis; peripheral neuropathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Updates on the Diagnosis of Dental and Oral Diseases, Second Edition

edited by

Sreekanth Kumar Mallineni

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2503 | Submission Open

Keywords: clinical photographs; cone-beam computerized tomography; imaging in dentistry; micro CT; periodontal disease; pulpitis; radiographs; root canal treatment; saliva; PCR; biofilms; malocclusions; digital dentistry

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Radiology in the Third Millennium: New Patient-Centered Diagnostic Approaches

edited by

and Fabrizio Urraro

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2395 | Submission Open

Keywords: radiology; diagnostics; patient-specific imaging; AI; deep learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Maternal–Fetal Medicine: 2nd Edition

edited by

Elena Bernad

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2364 | Submission Open

Keywords: pregnancy; fetus; ultrasound; maternal– fetal medicine; perinatal care high risk; obstetrics; complication; screening; diagnostics; fetal distress

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Emergency Medicine

edited by Evan Avraham Alpert

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1850 | Submission Open

Keywords: emergency medicine; trauma; sepsis; acute coronary syndrome; mortality

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1813 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

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