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  • Open Access

A Giant Basal Cell Carcinoma of the Scalp—A Clinical Case Study

  • Beata Zagórska,
  • Jacek Rutkowski,
  • Michał Kunc,
  • Jakub Żółkiewicz,
  • Urszula Maińska,
  • Michał Sobjanek and
  • Martyna Sławińska
Diagnostics2025, 15(24), 3114;https://doi.org/10.3390/diagnostics15243114 
(registering DOI)

8 December 2025

We describe the case of a 57-year-old female patient who reported to the dermatology outpatient clinic due to a large, ulcerated tumor of the scalp measuring approximately 12 × 10 cm. Based on the interview with the patient, it was determined t...

  • Opinion
  • Open Access

Thromboelastography to Support Clinical Decision Making in Patients with Peripheral Artery Disease

  • Anahita Dua,
  • Isabella Cieri,
  • Adriana Rodriguez,
  • Shiv Patel,
  • Dawn Barberi,
  • Joao D. Dias and
  • Jan Hartmann
Diagnostics2025, 15(24), 3113;https://doi.org/10.3390/diagnostics15243113 
(registering DOI)

8 December 2025

Peripheral artery disease (PAD) leads to reduced blood flow, primarily affecting the vessels of lower extremities. Symptoms include pain, cramping and reduced functional capacity, and patients are also at increased risk of cardiovascular complication...

  • Case Report
  • Open Access

Bone Marrow Edema and Tyrosine Kinase Inhibitors Treatment in Chronic Myeloid Leukemia

  • Sabina Russo,
  • Manlio Fazio,
  • Giuseppe Mirabile,
  • Raffaele Sciaccotta,
  • Fabio Stagno and
  • Alessandro Allegra
Diagnostics2025, 15(24), 3112;https://doi.org/10.3390/diagnostics15243112 
(registering DOI)

8 December 2025

Background and Clinical Significance: Tyrosine kinase inhibitors (TKIs) have transformed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) into a largely manageable chronic disease. However, off-target toxicities are increasingly re...

  • Article
  • Open Access

Thrombophilia-Related Single Nucleotide Variants and Altered Coagulation Parameters in a Cohort of Mexican Women with Recurrent Pregnancy Loss

  • Luis Felipe León-Madero,
  • Larissa López-Rodriguez,
  • Mónica Aguinaga-Ríos,
  • Samuel Vargas-Trujillo,
  • Angélica Castañeda-de-la-Fuente,
  • Paloma del Carmen Salazar-Villanueva,
  • Yanen Zaneli Ríos-Lozano,
  • Yuridia Martínez-Meza,
  • Monserrat Aglae Luna-Flores and
  • Alberto Hidalgo-Bravo
  • + 3 authors
Diagnostics2025, 15(24), 3111;https://doi.org/10.3390/diagnostics15243111 
(registering DOI)

7 December 2025

Background: Recurrent pregnancy loss (RPL) is a multifactorial condition in which genetic variants associated with thrombophilia may contribute to altered coagulation and adverse pregnancy outcomes. Objective: This study aimed to investigate the asso...

  • Article
  • Open Access

Explainable Federated Learning for Multi-Class Heart Disease Diagnosis via ECG Fiducial Features

  • Tanjila Alam Sathi,
  • Rafsan Jany,
  • AKM Azad,
  • Salem A. Alyami,
  • Naif Alotaibi,
  • Iqram Hussain and
  • Md Azam Hossain
Diagnostics2025, 15(24), 3110;https://doi.org/10.3390/diagnostics15243110 
(registering DOI)

7 December 2025

Background/Objectives: Cardiovascular disease (CVD) remains a leading cause of mortality and disability worldwide, with timely diagnosis critical for preventing long-term functional impairment. Electrocardiograms (ECGs) provide essential biomarkers o...

  • Article
  • Open Access
Diagnostics2025, 15(24), 3108;https://doi.org/10.3390/diagnostics15243108 
(registering DOI)

7 December 2025

Background: Tracheal breathing sounds (TBS) have demonstrated strong potential as a non-invasive, wakefulness-based diagnostic tool for obstructive sleep apnea (OSA); yet the relationship between specific upper airway anatomical features and the resu...

  • Article
  • Open Access
Diagnostics2025, 15(24), 3109;https://doi.org/10.3390/diagnostics15243109 
(registering DOI)

7 December 2025

Background: Precise localization of the mental foramen (MF) is essential to avoid mental nerve injury during implant placement, osteotomy, periapical surgery, and regional anesthesia. However, MF morphology and canal orientation show population-speci...

  • Article
  • Open Access
Diagnostics2025, 15(24), 3107;https://doi.org/10.3390/diagnostics15243107 
(registering DOI)

6 December 2025

Background: Rapid multiplex PCR assays promise faster and broader detection of uropathogens and resistance markers than conventional quantitative urine culture and susceptibility testing (C&S), but trial evidence linking PCR-guided management to...

  • Article
  • Open Access

Origin Variants of the Ascending Pharyngeal Artery and Sequential External Carotid Branching Classification

  • Rodica Narcisa Calotă,
  • Alexandra Diana Vrapciu,
  • Sorin Hostiuc,
  • Marius Ioan Rusu,
  • Răzvan Costin Tudose,
  • Mihail Silviu Tudosie,
  • George Triantafyllou,
  • Maria Piagkou and
  • Mugurel Constantin Rusu
Diagnostics2025, 15(24), 3106;https://doi.org/10.3390/diagnostics15243106 
(registering DOI)

6 December 2025

Background/Objectives: The ascending pharyngeal artery (APA) exhibits considerable variability in origin. Understanding its anatomy is essential for head and neck surgery, endovascular procedures, and skull base approaches. This study aimed to (1) sy...

  • Systematic Review
  • Open Access

Tear Film Alterations in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

  • Delius Mario Ghenciu,
  • Alexandra Ioana Dănilă,
  • Emil Robert Stoicescu,
  • Adrian Neagu and
  • Laura Andreea Ghenciu
Diagnostics2025, 15(24), 3104;https://doi.org/10.3390/diagnostics15243104 
(registering DOI)

6 December 2025

Background: Type 2 diabetes mellitus (T2DM) is increasingly recognized as affecting not only the retina but also the ocular surface. Chronic hyperglycemia can disrupt meibomian gland function, reduce tear secretion, and impair corneal sensitivity, le...

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Diagnostics - ISSN 2075-4418