Table of Contents
Molecules, Volume 23, Issue 1 (January 2018) – 219 articles
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Cover Story (view full-size image) These are small molecules with a 10-carbon skeleton called monoterpenes, which show great [...] Read more. These are small molecules with a 10-carbon skeleton called monoterpenes, which show great structural diversity within the iridoids group. The aglycone and glycoside forms of these compounds appear to target several pathological markers of Alzheimer’s disease both in vitro and in animal models. At a molecular level, beta amyloids (Aβ) formation, precipitation and neurotoxicity, mechanisms of tau phosphorylation, reactive oxygen species-Aβ crosstalk, and various oxidative and inflammatory cascades are targeted. What then would the prospects of these compounds be as drugs? View this paper