Special Issue "Melatonin as an Antioxidant and a Functionally Pleiotropic Molecule: Synthesis, Metabolism and Activities in Organisms"
Deadline for manuscript submissions: closed (30 June 2018)
Dr. Dun-Xian Tan
Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
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Interests: melatonin biology; antioxidant; antioxidative stress; melatonin systhesis and metabolism; mitochondria; chloroplast; plants
Melatonin is a phylogenetically ancient molecule. It is present in almost all organisms, from bacteria to humans. It is a functionally pleiotropic molecule and it is functional as an antioxidant, cancer inhibitor, inflammatory suppressor, immuno-enhancement agent, plant growth hormone and circadian rhythm regulator. It has been hypothesized that all these functions of melatonin was evolved from its antioxidant activity. Recently, the research focus was given to the synthesis and metabolism of this indolamine in different species, particulaly in plants and microorganisms and also its utilities in human health, agriculture and animal husbandry.
This Special Issue covers all aspects of pineal, melatonin and melatonin derivatives as related to their production and molecular actions in organisms from bacteria to human, including plants. Specific interests include the ability of melatonin and its metabolites to neutralize oxygen and nitrogen based toxic reactants and to protect against the associated molecular damage. This includes physical, psychological, chemical and drug-mediated injuries in animals and environmental biotic and abiotic stress in plants and microorganisms. Additionally to be included would be research articles and reviews related to novel aspects of melatonin synthesis, metabolism and applications in a variety of fields.Dr. Dun-Xian Tan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- melatonin synthesis
- melatonin metabolites
- free radical
- oxidative stress