Sulfur-containing amino acids, Methionine (Met) and Cysteine (Cys), are very susceptible to Reactive Oxygen Species (ROS). Therefore, sulfur-based reactions regulate many biological processes, playing a key role in maintaining cellular redox homeosta...
In this paper, we exploit the enhanced penetration reachable through inhomogeneous waves to induce hyperthermia in biological tissues. We will present a leaky-wave antenna inspired by the Menzel antenna which has been shortened through opportune desi...
Circulating tumor cells (CTCs) are cells that have separated from a solid cancerous lesion and entered the bloodstream. They play a crucial role in driving the metastatic spread to distant organs, which is the leading cause of cancer-related deaths....
This article studies a biological population model in the context of a fractional Caputo-Fabrizio operator using double Laplace transform combined with the Adomian method. The conditions for the existence and uniqueness of solution of the problem und...
We review processes by which different sounds, such as meditation music, mantra, kindness, or hatred expressions, and noises induce responses from cells and their components. We define ‘good’ or ‘bad’ sounds as those enhancing...
Over the last decades, nanomechanical sensors have received significant attention from the scientific community, as they find plenty of applications in many different research fields, ranging from fundamental physics to clinical diagnosis. Regarding...
Cavitation bubbles form in soft biological systems when subjected to a negative pressure above a critical threshold, and dynamically change their size and shape in a violent manner. The critical threshold and dynamic response of these bubbles are kno...
A theoretical model, based on the classical Pennes’ bioheat theory, incorporating various boundary conditions, was established and compared to analyze the influence of the latent heat of vaporization via simulation. The aim was to elucidate the...
The phenomenological universalities (PU) approach is employed to derive the Richards growth function in the unknown hyperbolic representation. The formula derived can be applied in theoretical modeling of sigmoid and involuted growth of biological sy...
A crucial step in the biomimicry process is the search and identification of biological models relevant to the design challenge. Anecdotal observations from case studies in authentic business contexts, as well as emerging literature on biomimicry met...
Gaining insight into osmotic pressure and its biological implications is pivotal for revealing mechanisms underlying numerous fundamental biological processes across scales and will contribute to the biomedical and pharmaceutical fields. This review...
In this study, we investigate the application of fractional calculus to the mathematical modeling of biological systems, focusing on fractional-order-in-time partial differential equations (FTPDEs). Fractional derivatives, especially those defined in...
The development of neuroanatomy and neurophysiology has revealed many new details about neurons’ operation over the past few decades, requiring modifications to their theoretical models. The development of computing technology enables us to con...
A sound theoretical ground is required for sustainability related concepts reconciliation and operationalization. The current study investigates the opportunities to conceive a homogenous sustainability model derived from theoretical ecology, using a...
Cellular morphogenesis is governed by the prepattern based on the symmetry-breaking emergence of dense protein clusters. Thus, a cluster of active GTPase Cdc42 marks the site of nascent bud in the baker’s yeast. An important biological question...
Mathematical models applied in contemporary theoretical and systems biology are based on some implicit ontological assumptions about the nature of organisms. This article aims to show that real organisms reveal a logic of internal causality transcend...
Background. The character of ablation processes with high-frequency electrical current is similar in most biological tissues; however, quantitative characteristics are very different. Consequently, mathematical models of the process have a lot of spe...
This paper focuses on the numerical modeling of drug diffusion in biological tissues using fractional time-dependent parabolic equations with non-local boundary conditions. The model includes a Caputo fractional derivative to capture the non-local ef...
10 December 2020
The developmental psychopathology clinical and theoretical framework has proposed a bio-psycho-social model that integrates biological, environmental, social, and psychological factors to disentangle the underpinning mechanisms of the intergeneration...
This paper studies the information interaction process in Bayesian theorem-based swarm systems. Through theoretical analysis, model construction, and simulation experiments, it explores how Bayesian decision-making utilizes information cascades to up...
The interactome, which represents the comprehensive network of molecular interactions within biological systems, has become a crucial framework for understanding cellular functions and disease mechanisms. However, current interactome models face sign...
The theory of electron spin has been proposed for a century, but the study of quantum effects in biological molecules is still in its infancy. Chirality-induced spin selectivity (CISS) is a very modern theory that can explain many biochemical phenome...
In classical concepts, theoretical models are built assuming that the dynamics of the complex system’s stuctural units occur on continuous and differentiable motion variables. In reality, the dynamics of the natural complex systems are much more comp...
In this review I show that four major kinds of theoretical approaches have been used to explain the scaling of metabolic rate in cells, organisms and groups of organisms in relation to system size. They include models focusing on surface-area related...
This paper presents an advanced simulation-based investigation of tumor growth and chemical diffusion in biological tissues, using ϑ-fractional stochastic integral equations. Based on the theoretical framework developed in [Fractal Fract. 20...
The origin of biological homochirality—defined as the preference of biological systems for only one enantiomer—has widespread implications in the study of chemical evolution and the origin of life. The activation—polymerization&mdas...
Lipophilicity is one of the most important parameters determining the pharmacodynamic and pharmacokinetic properties, as well as the toxicity of many compounds. The subject of the research was to determine the lipophilicity of betulin-1,4-quinone hyb...
The “Sonar Hopf” cochlea is a recently much advertised engineering design of an auditory sensor. We analyze this approach based on a recent description by its inventors Hamilton, Tapson, Rapson, Jin, and van Schaik, in which they exhibit the “Sonar H...
Primate vision is an active process that constructs a stable internal representation of the 3D world based on 2D sensory inputs that are inherently unstable due to incessant eye movements. We present here a mathematical framework for processing visua...
Gel electrolyte-gated organic electrochemical transistors (OECTs) are promising bioelectronic devices known for their high transconductance, low operating voltage, and integration with biological systems. Despite extensive research on the performance...
The implementation of stem-cell-based organoid culture more than ten years ago started a development that created new avenues for diagnostic analyses and regenerative medicine. In parallel, computational modelling groups realized the potential of thi...
Despite the recent rapid progress in high throughput measurements of biological data, it is still difficult to gather all of the reaction speed data in biological pathways. This paper presents a Petri net-based algorithm that can derive estimated val...
One key approach to analyzing the feasibility of energy extraction and generation technologies is to understand the net energy they contribute to society. These analyses most commonly focus on a simple comparison of a source’s expected energy outputs...
Almost half of all known proteins contain metal co-factors. Crucial for the flawless performance of a metalloprotein is the selection with high fidelity of the cognate metal cation from the surrounding biological fluids. Therefore, elucidating the fa...
Structural biological materials with integrated soft and hard phases are ubiquitous in nature. Over recent decades, bio-inspired hard-soft-integrated materials (BHSIMs) have shown excellent mechanical properties of drag reduction and abrasion resista...
The objective of this paper is to study a new mathematical model describing the human immunodeficiency virus (HIV). The model incorporates the impacts of cytotoxic T lymphocyte (CTL) immunity and antibodies with trilinear growth functions. The bounde...
Cooperation is essential for evolution of biological complexity. Recent work has shown game theoretic arguments, commonly used to model biological cooperation, can also illuminate the dynamics of chemical systems. Here we investigate the types of coo...
(1) Background: the theoretical modelling of reactions occurring in liquid phase is a research line of primary importance both in theoretical–computational chemistry and in the context of organic and biological chemistry. Here we present the mo...
Modelling is a tool used to decipher the biochemical mechanisms involved in transcriptional control. Experimental evidence in genetics is usually supported by theoretical models in order to evaluate the effects of all the possible interactions that c...
(1) Background: Microwave ablation (MWA) is a common tumor ablation surgery. Because of the high temperature of the ablation antenna, it is strongly destructive to surrounding vital tissues, resulting in high professional requirements for clinicians....
In dealing with the algorithmic aspects of intelligent systems, the analogy with the biological brain has always been attractive, and has often had a dual function. On the one hand, it has been an effective source of inspiration for their design, whi...
In this study, we develop a comprehensive mathematical model to analyze the dynamics of epidemic cholera, characterized by acute diarrhea due to pathogen overabundance in the human body. The model is first developed from a deterministic point of view...
In this paper, we study the stability analysis of two within-host virus dynamics models with antibody immune response. We assume that the virus infects n classes of target cells. The second model considers two types of infected cells: (i) latently in...
The use of surface plasmon resonance sensors allows for the fabrication of highly sensitive, label-free analytical devices. This contribution reports on a grating coupler to enable surface plasmon resonance studies using silver on silicon oxide techn...
The physics of active biological matter, such as bacterial colonies and bird flocks, exhibiting interesting self-organizing dynamical behavior has gained considerable importance in recent years. Current theoretical advances use techniques from hydrod...
Spectroscopic studies (FT-IR, Raman, 1H, and 13C NMR, UV-VIS) of caffeic acid (CFA) and its conjugates, i.e., caftaric acid (CTA), cichoric acid (CA), and cynarin (CY), were carried out. The antioxidant activity of these compounds was determined by a...
Biomimetic design, derived from the study of biological systems, has emerged as a pivotal methodology in contemporary art and design. By systematically integrating the morphological traits, structural principles, and functional mechanisms of living o...
Benzothiazoles are a set of molecules with a broad spectrum of biological applications. In particular, 2-(4-hydroxy-3-methoxyphenyl)-benzothiazole is a potential breast cancer cell suppressor whose mechanism of action has been previously reported. In...
Some biological systems, such as the tree frog, Litoria caerulea, and the bush-cricket, Tettigonia viridissima, have developed the ability to control adhesion by changing the curvature of their pads. Active control systems of adhesion inspired by the...
Theoretical neuroscience investigation shows valuable information on the mechanism for recognizing the biological movements in the mammalian visual system. This involves many different fields of researches such as psychological, neurophysiology, neur...
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