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  • Review
  • Open Access
53 Citations
9,037 Views
25 Pages

Biogenic Selenium Nanoparticles in Animal Nutrition: A Review

  • Svetlana Malyugina,
  • Sylvie Skalickova,
  • Jiri Skladanka,
  • Petr Slama and
  • Pavel Horky

9 December 2021

Selenium still represents a matter of debate in the scientific community. Bionanotechnology has introduced a whole new perspective on selenium use in animal nutrition. In recent years, attention has been focused on selenium nanoparticles prepared by...

  • Review
  • Open Access
83 Citations
7,594 Views
25 Pages

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

  • Elena G. Varlamova,
  • Egor A. Turovsky and
  • Ekaterina V. Blinova

6 October 2021

This review presents the latest data on the importance of selenium nanoparticles in human health, their use in medicine, and the main known methods of their production by various methods. In recent years, a multifaceted study of nanoscale complexes i...

  • Article
  • Open Access
32 Citations
3,685 Views
23 Pages

Despite the use of sorafenib as one of the most effective drugs for the treatment of liver cancer, its significant limitations remain—poor solubility, the need to use high doses with the ensuing complications on healthy tissues and organs, and...

  • Article
  • Open Access
16 Citations
2,844 Views
19 Pages

27 September 2023

The anti-cancer effects of selenium sources are well known. Among other things, selenium has been shown to have a pleiotropic effect, causing cancer cell death without affecting the healthy cell’s viability, or, in the case of brain cells, has...

  • Perspective
  • Open Access
15 Citations
2,903 Views
9 Pages

23 November 2022

Modern epidemics quickly spread across borders and continents with devastating effects on both human health and the world economy. This issue is made worse by the various ways that infections are spread, including through aerosol, droplets, and fomit...

  • Article
  • Open Access
76 Citations
4,837 Views
14 Pages

12 April 2022

Selenium nanoparticles (SeNPs) have attracted great attention in recent years due to their unique properties and potential bioactivities. While the production of SeNPs has been long reported, there is little news about the influence of reaction condi...

  • Review
  • Open Access
105 Citations
13,204 Views
40 Pages

15 December 2023

Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. “Green” synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. This review considers the...

  • Article
  • Open Access
78 Citations
8,251 Views
14 Pages

Effect of Selenium Nanoparticles on Germination of Hordéum Vulgáre Barley Seeds

  • Shahida Anusha Siddiqui,
  • Andrey Vladimirovich Blinov,
  • Alexander Vladimirovich Serov,
  • Alexey Alekseevich Gvozdenko,
  • Alexander Aleksandrovich Kravtsov,
  • Andrey Ashotovich Nagdalian,
  • Vladislav Viktorovich Raffa,
  • David Guramievich Maglakelidze,
  • Anastasiya Alexandrovna Blinova and
  • Salam A. Ibrahim
  • + 2 authors

19 July 2021

Within the framework of this study, the effect of nanoparticles of the essential trace element selenium stabilized by Polyvinylpirrolidone (PVP) C15 (8 ± 2 kDa) and ascorbic acid on the germination of barley seeds has been studied. Selenium nanoparti...

  • Review
  • Open Access
23 Citations
4,076 Views
21 Pages

The liver is the body’s largest gland, and regulates a wide variety of physiological processes. The work of the liver can be disrupted in a variety of pathologies, the number of which is several hundred. It is extremely important to monitor the...

  • Article
  • Open Access
12 Citations
2,804 Views
10 Pages

Selenium Nanoparticles as Potential Antioxidants to Improve Semen Quality in Boars

  • Pavel Horky,
  • Lenka Urbankova,
  • Iqra Bano,
  • Tomas Kopec,
  • Pavel Nevrkla,
  • Magdalena Pribilova,
  • Daria Baholet,
  • Pompido Chilala,
  • Petr Slama and
  • Sylvie Skalickova

30 July 2023

Selenium is an essential compound which can influence the fertility of boars by a greater margin. In past decades, research was mainly focused on a bioavailability of various selenium forms and the effect on semen quality. Recently, nanotechnology ha...

  • Review
  • Open Access
9 Citations
4,340 Views
20 Pages

An Updated Review of the Antimicrobial Potential of Selenium Nanoparticles and Selenium-Related Toxicological Issues

  • Tainá Pereira da Silva Oliveira,
  • Alan Kelbis Oliveira Lima and
  • Luís Alexandre Muehlmann

Discovered in mid-1817 by Jöns Jacob Berzelius, selenium, belonging to Group 16 of the periodic table is an essential trace element for human and animal health, due to its biocompatibility and bioavailability. Additionally, it is known for havin...

  • Review
  • Open Access
23 Citations
3,513 Views
15 Pages

26 June 2024

This review describes and summarizes, for the first time, the molecular mechanisms of the cytotoxic effect of selenium nanoparticles of various origins on hepatocellular carcinoma cells. The text provides information from recent years indicating the...

  • Review
  • Open Access
3 Citations
1,371 Views
27 Pages

Selenium Nanoparticles as Versatile Delivery Tools

  • Amir Nasrolahi Shirazi,
  • Rajesh Vadlapatla,
  • Ajoy Koomer,
  • Kyle Yep and
  • Keykavous Parang

Selenium nanoparticles (SeNPs) have emerged as promising metal-based nanoparticles for drug delivery due to their unique physicochemical properties, intrinsic bioactivity, and biocompatibility. SeNPs offer a lower toxicity, higher bioavailability, an...

  • Communication
  • Open Access
19 Citations
5,758 Views
9 Pages

17 June 2019

We synthesized a hybrid nanocomposite comprised of selenium nanoparticles coated with a thin layer of a conductive polymer, poly(3,4-ethylenedioxythiophene), and studied its thermoelectric properties. The conductive polymer layer on the surface of na...

  • Review
  • Open Access
15 Citations
4,317 Views
19 Pages

29 July 2024

In recent years, selenium nanoparticles (SeNPs) have attracted expanding consideration, particularly in the nanotechnology field. This element participates in important biological processes, such as antioxidant defense, immune function, and thyroid h...

  • Article
  • Open Access
18 Citations
2,911 Views
32 Pages

Antifibrotic Effect of Selenium-Containing Nanoparticles on a Model of TAA-Induced Liver Fibrosis

  • Elena G. Varlamova,
  • Michail Victorovich Goltyaev,
  • Vladimir Vladimirovich Rogachev,
  • Sergey V. Gudkov,
  • Elena V. Karaduleva and
  • Egor A. Turovsky

28 November 2023

For the first time, based on the expression analysis of a wide range of pro- and anti-fibrotic, pro- and anti-inflammatory, and pro- and anti-apoptotic genes, key markers of endoplasmic reticulum stress (ER-stress), molecular mechanisms for the regul...

  • Article
  • Open Access
1 Citations
660 Views
16 Pages

6 October 2025

Background: Silver fluoride medicaments effectively arrest caries progression but cause permanent staining. Nanoparticles are increasingly utilised in paediatric dentistry due to their antimicrobial properties. Aim: This study reports the synthesis a...

  • Review
  • Open Access
26 Citations
4,507 Views
23 Pages

11 January 2024

Strokes rank as the second most common cause of mortality and disability in the human population across the world. Currently, available methods of treating or preventing strokes have significant limitations, primarily the need to use high doses of dr...

  • Article
  • Open Access
4 Citations
2,663 Views
12 Pages

Spectroscopic Analysis of Selenium Nanoparticles Synthesized by Saccharomyces boulardii for the Production of Craft Beer

  • Lourdes González-Salitre,
  • Luis Guillermo González-Olivares,
  • Alexis Alejandro Salazar-Navarro,
  • David Cervantes-García,
  • Dagoberto Durán-Hernández,
  • Ricardo Torres-Ramos,
  • Mary Triny Beleño-Cabarcas and
  • Ulin Antobelli Basilio-Cortes

Selenium is an essential micronutrient which is found in many foods and beverages in low concentrations. Craft beer, one of the most widely consumed fermented beverages globally, presents a strategic opportunity for selenium intake through organic na...

  • Article
  • Open Access
296 Citations
17,483 Views
10 Pages

Biomolecule-Mediated Synthesis of Selenium Nanoparticles using Dried Vitis vinifera (Raisin) Extract

  • Garima Sharma,
  • Ashish Ranjan Sharma,
  • Riju Bhavesh,
  • Jongbong Park,
  • Bilguun Ganbold,
  • Ju-Suk Nam and
  • Sang-Soo Lee

27 February 2014

Biomolecule-mediated nanoparticle synthesis has recently gained the attention of researchers due to its ecofriendly and non-toxic nature. Metabolites from plant extracts represent a better alternative to chemical methods to fulfill the growing demand...

  • Review
  • Open Access
87 Citations
7,974 Views
12 Pages

Uses of Selenium Nanoparticles in the Plant Production

  • Iqra Bano,
  • Sylvie Skalickova,
  • Hira Sajjad,
  • Jiri Skladanka and
  • Pavel Horky

3 November 2021

Plant production today depends on the ability of agriculturists to transport and recycle minerals, particularly those minerals which are nutritionally important to animals and human beings, through various agriculture products. It is important to not...

  • Article
  • Open Access
29 Citations
3,527 Views
20 Pages

Selenium is an essential trace element for the proper functioning of the human body. In recent years, great attention has been paid to selenium nanoparticles (SeNPs) due to their potential for medicinal applications. In this study, herbal extracts we...

  • Article
  • Open Access
21 Citations
3,572 Views
22 Pages

Enhancing the Activity of Carboxymethyl Cellulase Enzyme Using Highly Stable Selenium Nanoparticles Biosynthesized by Bacillus paralicheniformis Y4

  • Yidan Wang,
  • Yonghe Yu,
  • Yuhua Duan,
  • Qin Wang,
  • Xin Cong,
  • Yi He,
  • Chao Gao,
  • Muhammad Hafeez,
  • Saad Jan and
  • Zhangqian Wang
  • + 2 authors

18 July 2022

The inorganic selenium is absorbed and utilized inefficiently, and the range between toxicity and demand is narrow, so the application is strictly limited. Selenium nanoparticles have higher bioactivity and biosafety properties, including increased a...

  • Article
  • Open Access
16 Citations
3,264 Views
18 Pages

Highly Efficient Biotransformation and Production of Selenium Nanoparticles and Polysaccharides Using Potential Probiotic Bacillus subtilis T5

  • Yuhua Duan,
  • Mengjun Li,
  • Sishang Zhang,
  • Yidan Wang,
  • Jieya Deng,
  • Qin Wang,
  • Tian Yi,
  • Xingxing Dong,
  • Shuiyuan Cheng and
  • Zhangqian Wang
  • + 2 authors

1 December 2022

Selenium is an essential microelement required for human health. The biotransformation of selenium nanoparticles has attracted increasing attention in recent years. However, little of the literature has investigated the comprehensive evaluation of th...

  • Article
  • Open Access
2 Citations
1,368 Views
14 Pages

Comparative Study of Red and Grey Selenium Nanoparticles on Organ-Specific Selenium Deposition and Growth Performance in Japanese Quails

  • Aya Ferroudj,
  • Arjun Muthu,
  • Daniella Sári,
  • Gréta Törős,
  • Áron Beni,
  • Levente Czeglédi,
  • Renáta Knop,
  • Hassan El-Ramady and
  • József Prokisch

Selenium (Se) is an essential trace element required for various physiological functions in agriculture. Nanotechnology is applied to produce selenium nanoparticles (SeNPs) that offer new advantages, enhancing their bioavailability and reducing toxic...

  • Article
  • Open Access
44 Citations
3,633 Views
17 Pages

3 August 2021

To date, there are practically no data on the mechanisms of the selenium nanoparticles action on calcium homeostasis, intracellular signaling in cancer cells, and on the relationship of signaling pathways activated by an increase in Ca2+ in the cytos...

  • Review
  • Open Access
60 Citations
8,300 Views
24 Pages

9 February 2024

Selenium is a trace and necessary micronutrient for human, animal, and microbial health. Many researchers have recently been interested in selenium nanoparticles (SeNPs) due to their biocompatibility, bioavailability, and low toxicity. As a result of...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,494 Views
12 Pages

Lignin and Starch Derivatives with Selenium Nanoparticles for the Efficient Reduction of Dyes and as Polymer Fillers

  • Anna Modrzejewska-Sikorska,
  • Mariola Robakowska,
  • Emilia Konował,
  • Hubert Gojzewski,
  • Łukasz Gierz,
  • Bartosz Wieczorek,
  • Łukasz Warguła and
  • Wiktor Łykowski

30 June 2023

Selenium nanoparticles (SeNPs) were synthesized and stabilized by biopolymers, namely, sodium lignosulfonate (LS) and starch sodium octenyl succinate (OSA). The obtained selenium nanoparticles were studied for their catalytic activity in the reductio...

  • Article
  • Open Access
32 Citations
3,409 Views
17 Pages

Preparation of Paclitaxel-Encapsulated Bio-Functionalized Selenium Nanoparticles and Evaluation of Their Efficacy against Cervical Cancer

  • Soumya Menon,
  • Santhoshkumar Jayakodi,
  • Kanti Kusum Yadav,
  • Prathap Somu,
  • Mona Isaq,
  • Venkat Kumar Shanmugam,
  • Amballa Chaitanyakumar and
  • Nagaraj Basavegowda

27 October 2022

The potentiality of nanomedicine in the cancer treatment being widely recognized in the recent years. In the present investigation, the synergistic effects of chitosan-modified selenium nanoparticles loaded with paclitaxel (PTX-chit-SeNPs) were studi...

  • Article
  • Open Access
3 Citations
1,663 Views
16 Pages

Effect of Different Selenium Species on Indole-3-Acetic Acid Activity of Selenium Nanoparticles Producing Strain Bacillus altitudinis LH18

  • Mengjun Li,
  • Rui Yang,
  • Nana Li,
  • Siyang Zhao,
  • Shiya Wei,
  • Sishang Zhang,
  • Jue Gong,
  • Jie Song,
  • Jun-Ran Kim and
  • Shuiyuan Cheng
  • + 3 authors

Acting as a growth regulator, Indole-3-acetic acid (IAA) is an important phytohormone that can be produced by several Bacillus species. However, few studies have been published on the comprehensive evaluation of the strains for practical applications...

  • Article
  • Open Access
34 Citations
6,815 Views
16 Pages

13 January 2023

Selenium nanoparticles (SeNPs) are the object of great interest due to their potential to be used in many areas of industry and medicine. Work is still underway on their synthesis methods; however, green methodologies are becoming more and more popul...

  • Article
  • Open Access
13 Citations
2,874 Views
12 Pages

Synthesis of Selenium Nanoparticles Modified by Quaternary Chitosan Covalently Bonded with Gallic Acid

  • Alexey Lunkov,
  • Mariya Konovalova,
  • Balzhima Shagdarova,
  • Yuliya Zhuikova,
  • Alla Il’ina and
  • Valery Varlamov

29 April 2023

Quaternary chitosan derivative with covalently bonded antioxidant (QCG) was used as media for synthesis of selenium nanoparticles (SeNPs). SeNPs were characterized using AFM, TEM, and DLS methods. The data confirmed the formation of stable nanopartic...

  • Communication
  • Open Access
1 Citations
464 Views
10 Pages

Effect of Red and Grey Selenium Nanoparticles on Yeast Growth: Short Communication

  • Aya Ferroudj,
  • Dávid Semsey,
  • Daniella Sári and
  • József Prokisch

9 December 2025

Selenium nanoparticles (SeNPs) present a promising alternative to toxic inorganic selenium salts, yet the differential bioactivity between their allotropic forms—amorphous red (RSeNPs) and crystalline grey (GSeNPs)—is not fully determined...

  • Article
  • Open Access
47 Citations
4,900 Views
15 Pages

Evaluation of Antibacterial Activity of Selenium Nanoparticles against Food-Borne Pathogens

  • Qunying Yuan,
  • Rong Xiao,
  • Mojetoluwa Afolabi,
  • Manjula Bomma and
  • Zhigang Xiao

Selenium is an essential micronutrient for all mammals and plays an important role in maintaining human physiological functions. Selenium nanoparticles (SeNPs) have been shown to demonstrate antioxidant and antimicrobial activity. The objective of th...

  • Article
  • Open Access
45 Citations
5,956 Views
14 Pages

The Effect of Selenium Nanoparticles on the Osteogenic Differentiation of MC3T3-E1 Cells

  • Sang-Cheol Lee,
  • Na-Hyun Lee,
  • Kapil D. Patel,
  • Tae-Su Jang,
  • Jonathan Campbell Knowles,
  • Hae-Won Kim,
  • Hae-Hyoung Lee and
  • Jung-Hwan Lee

23 February 2021

Reactive oxygen species (ROS) regulate various functions of cells, including cell death, viability, and differentiation, and nanoparticles influence ROS depending on their size and shape. Selenium is known to regulate various physiological functions,...

  • Article
  • Open Access
23 Citations
4,259 Views
17 Pages

29 September 2020

Current chemotherapeutic drugs, although effective, lack cell-specific targeting, instigate adverse side effects in healthy tissue, exhibit unfavourable bio-circulation and can generate drug-resistant cancers. The synergistic use of nanotechnology an...

  • Review
  • Open Access
29 Citations
6,761 Views
26 Pages

16 February 2025

Nanoparticle-based strategies have emerged as transformative tools for addressing critical challenges in sustainable agriculture, offering precise modulation of plant–environment interactions through enhanced biocompatibility and stimuli-respon...

  • Article
  • Open Access
2 Citations
1,265 Views
21 Pages

Selenium nanoparticles (SeNPs) show enormous potential in biomedical applications. In recent years, green methods of their synthesis have become very popular. In this work, the influence of green synthesis conditions on the properties of the obtained...

  • Article
  • Open Access
81 Citations
6,019 Views
17 Pages

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

  • Mustafa Mohsen El-Zayat,
  • Mostafa M. Eraqi,
  • Hani Alrefai,
  • Ayman Y. El-Khateeb,
  • Marwan A. Ibrahim,
  • Hashim M. Aljohani,
  • Maher M. Aljohani and
  • Moustafa Mohammed Elshaer

22 March 2021

The current work aimed to synthesize selenium and zinc nanoparticles using the aqueous extract of Ephedra aphylla as a valuable medicinal plant. The prepared nanoparticles were characterized by TEM, zeta potential, and changes in the phytochemical co...

  • Review
  • Open Access
9 Citations
5,088 Views
34 Pages

Selenium Nanoparticles in Critical Illness—Anti-Inflammatory and Antioxidant Effects

  • Celia María Curieses Andrés,
  • José Manuel Pérez de la Lastra,
  • Elena Bustamante Munguira,
  • Celia Andrés Juan and
  • Eduardo Pérez-Lebeña

14 February 2025

Selenium (Se) has important anti-inflammatory and antioxidant activities, plays an important role in the immune system through redox balance, and is part of selenoproteins. In patients who are critically ill, Se supplementation causes alterations in...

  • Review
  • Open Access
39 Citations
4,314 Views
28 Pages

30 September 2022

As an essential micronutrient, selenium participates in numerous life processes and plays a key role in human health. In the past decade, selenium nanoparticles (SeNPs) have attracted great attention due to their excellent functionality for potential...

  • Article
  • Open Access
7 Citations
2,130 Views
13 Pages

3 November 2024

Fagopyrum dibotrys is a herbal plant. Selenium (Se) is a beneficial element for plants; selenium nanoparticles (SeNPs) are gaining importance in food and agriculture due to their low toxicity and high activity. This study revealed that foliar applica...

  • Article
  • Open Access
41 Citations
5,489 Views
23 Pages

Selenium’s (Se) chemopreventative and therapeutic properties have attracted attention in nanomedicine. Se nanoparticles (SeNPs) retain these properties of Se while possessing lower toxicity and higher bioavailability, potentiating their use in gene d...

  • Article
  • Open Access
33 Citations
3,517 Views
16 Pages

Multifunctional Dyeing of Wool Fabrics Using Selenium Nanoparticles

  • Tarek Abou Elmaaty,
  • Sally Raouf,
  • Khaled Sayed-Ahmed and
  • Maria Rosaria Plutino

4 January 2022

This work aims to utilize selenium nanoparticles (Se-NPs) as a novel dyestuff, which endows wool fibers with an orange color because of their localized surface plasmon resonance. The color characteristics of dyed fibers were evaluated and analyzed. T...

  • Article
  • Open Access
44 Citations
4,849 Views
20 Pages

Aspergillus terreus-Mediated Selenium Nanoparticles and Their Antimicrobial and Photocatalytic Activities

  • Ebrahim Saied,
  • Alsayed E. Mekky,
  • Abdulaziz A. Al-Askar,
  • Abdelrahman F. Hagag,
  • Abdullah A. El-bana,
  • Mohamed Ashraf,
  • Abdelrahman Walid,
  • Taha Nour,
  • Mahmoud M. Fawzi and
  • Amr H. Hashem
  • + 1 author

4 March 2023

Selenium (Se) is a nutritional component necessary for animal and plant development and reproduction. Selenium nanoparticles (SeNPs) have a high absorption rate during routine supplementation. In the current study, a cell-free extract of Aspergillus&...

  • Article
  • Open Access
30 Citations
3,353 Views
21 Pages

26 November 2021

In recent years, much attention has been paid to the study of the therapeutic effect of the microelement selenium, its compounds, especially selenium nanoparticles, with a large number of works devoted to their anticancer effects. Studies proving the...

  • Article
  • Open Access
33 Citations
5,561 Views
19 Pages

Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential

  • Anas Ahzaruddin Ahamad Tarmizi,
  • Nik Nasihah Nik Ramli,
  • Siti Hajar Adam,
  • Maisarah Abdul Mutalib,
  • Mohd Helmy Mokhtar and
  • Shirley Gee Hoon Tang

10 July 2023

The advancement in nanotechnology is the trigger for exploring the synthesis of selenium nanoparticles and their use in biomedicine. Therefore, this study aims to synthesize selenium nanoparticles using M. oleifera as a reducing agent and evaluate th...

  • Article
  • Open Access
1 Citations
2,005 Views
18 Pages

Effect of Cyclodextrins Formulated in Liposomes and Gold and Selenium Nanoparticles on siRNA Stability in Cell Culture Medium

  • Betzaida Castillo Cruz,
  • Sandra Chinapen Barletta,
  • Bryan G. Ortiz Muñoz,
  • Adriana S. Benitez-Reyes,
  • Omar A. Amalbert Perez,
  • Alexander C. Cardona Amador,
  • Pablo E. Vivas-Mejia and
  • Gabriel L. Barletta

8 October 2024

Background: Encapsulation of siRNA fragments inside liposome vesicles has emerged as an effective method for delivering siRNAs in vitro and in vivo. However, the liposome’s fluid-phospholipid bilayer of liposomes allows siRNA fragments to diffu...

  • Article
  • Open Access
81 Citations
8,283 Views
14 Pages

4 November 2019

Systemic messenger RNA (mRNA) delivery, although still in its infancy, holds immense potential for application in cancer vaccination and immunotherapy. Its advantages over DNA transfection make it attractive in applications where transient expression...

  • Article
  • Open Access
21 Citations
3,589 Views
18 Pages

Effects of Schisandra chinensis Polysaccharide-Conjugated Selenium Nanoparticles on Intestinal Injury in Mice

  • Hongxu Du,
  • Xiaoyan Tan,
  • Zhangxun Li,
  • Hong Dong,
  • Lijuan Su,
  • Zhengke He,
  • Qi Ma,
  • Shiqi Dong,
  • Mythili Ramachandran and
  • Liting Cao
  • + 1 author

4 March 2023

Schisandra chinensis polysaccharide (SCP) is an experimental therapeutic for the treatment of intestinal injury. Selenium nanoparticle modification can improve the bioactivity of polysaccharides. In this study, SCP was firstly extracted and purified...

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