Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry

Almuqrin, Amjad; Seneviratne, Chaminda Jayampath; Walsh, Laurence J.; Zafar, Sobia

doi:10.3390/dj13100456

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Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry

¹

School of Dentistry, The University of Queensland, Brisbane, QLD 4006, Australia

²

School of Dentistry, The University of Hail, Hail 2440, Saudi Arabia

^*

Authors to whom correspondence should be addressed.

Dent. J. 2025, 13(10), 456; https://doi.org/10.3390/dj13100456

Submission received: 14 August 2025 / Revised: 20 September 2025 / Accepted: 28 September 2025 / Published: 6 October 2025

(This article belongs to the Section Restorative Dentistry and Traumatology)

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Abstract

Background: Silver fluoride medicaments effectively arrest caries progression but cause permanent staining. Nanoparticles are increasingly utilised in paediatric dentistry due to their antimicrobial properties. Aim: This study reports the synthesis and characterisation of silver and selenium nanoparticles stabilised with natural agents. Methods: Six silver and selenium nanoparticles were chemically synthesised and stabilised using biocompatible eco-friendly capping agents, including casein, bovine serum albumin, chitosan, citrate, and tannic acid. Characterisation was performed using Tyndall scattering, UV-Vis spectroscopy, transmission electron microscopy, and ICP-OES. Results: The synthesised particles were spherical in shape, ranging in size from 2.5 to 24 nm for silver and 35 to 43 nm for selenium. Elemental analysis confirmed the absence of heavy metals. Conclusions: These findings highlight the successful synthesis of capped silver and selenium nanoparticles. The observed characteristics suggest potential relevance for future antimicrobial applications in paediatric dentistry.

Keywords: nanotechnology; metal nanoparticles; silver nanoparticles; selenium nanoparticles; nanoparticles synthesis; biocompatible capping agents; paediatric dentistry

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MDPI and ACS Style

Almuqrin, A.; Seneviratne, C.J.; Walsh, L.J.; Zafar, S. Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry. Dent. J. 2025, 13, 456. https://doi.org/10.3390/dj13100456

AMA Style

Almuqrin A, Seneviratne CJ, Walsh LJ, Zafar S. Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry. Dentistry Journal. 2025; 13(10):456. https://doi.org/10.3390/dj13100456

Chicago/Turabian Style

Almuqrin, Amjad, Chaminda Jayampath Seneviratne, Laurence J. Walsh, and Sobia Zafar. 2025. "Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry" Dentistry Journal 13, no. 10: 456. https://doi.org/10.3390/dj13100456

APA Style

Almuqrin, A., Seneviratne, C. J., Walsh, L. J., & Zafar, S. (2025). Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry. Dentistry Journal, 13(10), 456. https://doi.org/10.3390/dj13100456

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Tailored Synthesis and Profiling of Capped Silver and Selenium Nanoparticles for Topical Applications in Paediatric Dentistry

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