A lack of guidance on economic evaluations for oral cancer screening programs forms a challenge for policymakers and researchers to fill the knowledge gap on their cost-effectiveness. This systematic review thus aims to compare the outcomes and desig...
During the assembly process, there are inevitable variations and noise factors in the material properties, process parameters and screening scheme, which may affect the quality of the product. Using the stress-strength model, an evaluated screening s...
24 November 2022
In the federal state of Germany, Saxony-Anhalt, colorectal cancer is the second most frequent cause of death among cancer patients. In order to identify cancer precursors early, colorectal cancer screenings are essential. In this context, health info...
Newborn Bloodspot Screening (NBS) has existed for over 60 years, having been initiated by Guthrie in the U.S. In the Philippines, NBS was introduced in 1996 and later was supported by legislation. The NBS program now includes 29 conditions, covering...
(1) Background: This population-based study aimed at identifying the factors associated with the likelihood of detection of stage IA cervical carcinoma—versus the detection of stage IB through IV cervical carcinoma—and the patterns of sur...
The introduction of tandem mass spectrometry (MS/MS) to clinical laboratories and the advent of expanded newborn screening (NBS) were crucial changes to public health programs worldwide. Speed, robustness, accuracy, selectivity, and specificity of an...
Pilot studies to detect newborns with Duchenne Muscular Dystrophy (DMD) by newborn bloodspot screening (NBS) have been conducted under the New York State Newborn Screening Program (NYS) and are currently in progress as part of the Early Check Program...
Drought is a major limiting factor in the cultivation of Sophora alopecuroides in China’s arid and semi-arid regions. This study aimed to identify drought-resistant S. alopecuroides ecotypes and explore key drought tolerance indicators during g...
We conducted an updated economic evaluation, from a healthcare system perspective, to compare the relative effectiveness and efficiency of eight Lynch syndrome (LS) screening protocols among newly diagnosed colorectal cancer (CRC) patients. We develo...
Functional Movement Screening (FMS) is a test used to evaluate fundamental movement patterns in the human body and identify functional limitations. However, the challenge of carrying out an automated assessment of FMS is that complex human movements...
Serum and glucocorticoid-regulated kinase 1 (SGK1), as a serine threonine protein kinase of the AGC family, regulates different enzymes, transcription factors, ion channels, transporters, and cell proliferation and apoptosis. Inhibition of SGK1 is co...
Advanced glycation end products (AGEs) formed via glycation reactions negatively impact skin health by diminishing barrier function and elasticity and causing dullness. This study systematically evaluated the inhibitory and degradative capabilities o...
An improved multi-objective particle swarm optimization algorithm is combined with a machine learning classifier to meet the needs of underwater manned/unmanned cooperative warfare architecture evaluation. Firstly, based on the traditional Cauchy var...
Sweden has one neonatal screening laboratory, receiving 115 to 120 thousand samples per year. Among the one million babies screened by tandem mass spectrometry from November 2010 until July 2019, a total of 665 babies were recalled and 311 verified a...
The adaptability of bermudagrass genotypes to high-pH saline–alkali conditions was investigated through a comprehensive evaluation of 38 genotypes during the seedling stage. For this purpose, two distinct treatments were established: exposure t...
Good information is needed to demonstrate that a screening programme is meeting its objectives, to measure performance against standards and to ensure that action is taken if standards are not met. In 2010, the NHS Sickle Cell and Thalassaemia (SCT)...
Cost-effectiveness (CEA) and cost–utility analyses (CUA) have become popular types of economic evaluations (EE) used for evidence-based decision-making in healthcare resource allocation. Newborn screening programs (NBS) can have significant cli...
This study was undertaken to identify oat (Avena sativa L.) varieties optimal for cultivation in the Jiuquan region, China, in 2021. A selection of 27 domestic and international oat varieties were analyzed, considering ten key agronomic traits, inclu...
Butyrylcholinesterase (BChE), plays a critical role in alleviating the symptoms of Alzheimer’s disease (AD) by regulating acetylcholine levels, emerging as an attractive target for AD treatment. This study employed a quantitative structure&ndas...
Most of the targeted discoveries in tuberculosis research have covered previously explored chemical structures but neglected physiochemical properties. Until now, no efficient prediction tools have been developed to discriminate the novelty of screen...
Argillaceous fine silt hydrate reservoirs have a clay content of 20–25% and a median sand particle size of 10–15 um. Sand control is extremely difficult, restricting the continuous and stable testing of gas hydrate. This paper focuses on...
Sea Island cotton is renowned for its superior fiber quality. Although mechanical harvesting has the potential to significantly increase efficiency and reduce the production cost of Sea Island cotton, there is still little research in this area. In t...
Background: Diagnostic blood tests have the potential to identify lung cancer in people at high risk. We assessed the cost-effectiveness of a lung cancer screening intervention, using the EarlyCDT®-Lung Test (ECLS) with subsequent X-ray and low-d...
Background: A prospective cohort study was undertaken within the PERSPECTIVE I&I project to evaluate healthcare resource utilization and costs associated with breast cancer risk assessment and screening and overall costs stratified by risk level,...
Currently, screen content images (SCIs) are widely used in our modern society. However, since SCIs have distinctly different properties compared to natural images, traditional quality assessment methods of natural images cannot precisely evaluate the...
Quantitative Structure Activity Relationship (QSAR) models can inform on the correlation between activities and structure-based molecular descriptors. This information is important for the understanding of the factors that govern molecular properties...
14 December 2016
Conducting a full indoor air quality (IAQ) assessment in air-conditioned offices requires large-scale material and manpower resources. However, an IAQ index can be adopted as a handy screening tool to identify any premises (with poor IAQ) that need m...
Florida’s Newborn Screening Program campaign aims to increase the awareness and participation of birthing facilities, providers, and parents. This evaluation aimed to determine the effectiveness and reach of the Newborn Screening Program (NBS)...
Breath alcohol screening is important for traffic safety, access control and other areas of health promotion. A family of sensor devices useful for these purposes is being developed and evaluated. This paper is focusing on algorithms for the determin...
The mine ventilation system is an indispensable component to improve coal mining efficiency and ensure the safety of production. Only by clearly grasping the comprehensive evaluation quality of the ventilation system can effective countermeasures be...
Cluster headache (CH), a severe primary headache, is often misdiagnosed and mismanaged. The aim of this study was to develop and evaluate a screening tool to aid the diagnosis of CH. We developed a novel 12-item screening tool. This was comprised of...
Background/Objectives: Adverse childhood experiences (ACEs) are traumatic childhood events that can disrupt neurologic, endocrine, and immune regulation and increase the risk for poor health outcomes. This Trauma-Informed ACE Screening and Interventi...
This paper proposes a framework for screening and evaluating seismic performance of river earth embankments on liquefiable foundation soils. The framework is executed in the order of simplest screening by soil liquefaction potential map to preliminar...
Cardiomyopathy is a major cause of heart failure caused by abnormalities of the heart muscles that make it harder for it to fill or eject blood. With technological advances, it is important for patients and families to understand that there are poten...
Timely screening and surveillance of children for developmental delay and social–emotional learning difficulties are essential in Low- and Middle-Income Countries like India. Screening measures like the Parents’ Evaluation of Developmenta...
Background/Objectives: Diabetic retinopathy (DR) is the leading cause of preventable blindness among working-age adults. Early detection through screening programs is essential for managing the condition and preventing visual impairment. In Portugal,...
Screening for severe combined immunodeficiency (SCID) was added to the New Zealand national newborn screening programme in December 2017. Documentation pertaining to the application to add SCID to the panel and screening results over the first three...
As a traditional natural medicine for treating many kinds of diseases, Gnetum parvifolium showed apparent inhibition on xanthine oxidase (XO). In this study, ultrafiltration combined with liquid chromatography-mass spectrometry (LC-MS) is used for th...
γ-Secretase is an intramembrane aspartyl protease that is important in regulating normal cell physiology via cleavage of over 100 transmembrane proteins, including Amyloid Precursor Protein (APP) and Notch family receptors. However, aberrant pr...
Mechanized harvesting is a crucial step in the agricultural production of foxtail millet (Setaria italica), as its peduncles are susceptible to bending and breaking during the harvesting process, leading to yield losses and deterioration in grain qua...
In the context of automatic generation methods for tolerance specifications, the current approach entails designers subjectively selecting geometric tolerances suitable for annotation from the tolerance types generated through automatic reasoning. Th...
Microorganisms have significant potential to control fungal contamination in various foods. However, the identification of strains that exhibit robust antifungal activity poses challenges due to highly context-dependent responses. Therefore, to fully...
Geochemical exploration offers a cost-effective means of identifying subsurface oil and gas accumulations through the detection of volatile organic compounds (VOCs), which serve as markers of underlying hydrocarbon systems. These indicators may appea...
This research describes the design and evaluation of screening smoke compositions based on red phosphorus (RP), in open field conditions. In defense applications, smoke is used for both signaling and screening. Defense forces use smoke screening over...
A high-throughput platform for assessing the activity of synthetic or natural compounds on the motility and development of Haemonchus contortus larvae has been established for identifying new anthelmintic compounds active against strongylid nematodes...
Feeding and swallowing disorders (FSD) are common during childhood, with a prevalence of 85% in children with neurodevelopmental disorders. A comprehensive screening is essential to identify FSD and improve health outcomes in a clinical setting. This...
Nutritional risk screening (NRS) is not yet established in many clinical settings. This study aimed to evaluate the efficacy of two NRS tools; the Paediatric Yorkhill Malnutrition Score (PYMS) and the Screening Tool for the Assessment of Malnutrition...
Between 2005 and 2021, 49 cases of classical congenital adrenal hyperplasia were diagnosed in New Zealand, 39 were detected in newborns and 10 were not detected by screening. Currently, for every case of CAH detected by screening, 10 false-positive t...
Undiagnosed and untreated tyrosinemia type 1 (TT1) individuals carry a significant risk for developing liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). Elevated succinylacetone (SA) is pathognomonic for TT1 and therefore often used as ma...
Screening for nitrogen (N)-efficient germplasm to achieve high yield and high N efficiency is an important strategy to enhance the sustainability of modern agriculture. In this study, 127 peanut (Arachis hypogaea L.) germplasm resources were comprehe...
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