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3,919 Results Found

  • Article
  • Open Access
31 Citations
6,839 Views
13 Pages

18 April 2018

Response surface methodology is used to optimize the leaching process for refractory flotation copper tailings. The proportion of the refractory combination oxide copper (chrysocolla) is 64.84%. At present, few studies have examined the leaching of...

  • Feature Paper
  • Article
  • Open Access
34 Citations
4,153 Views
15 Pages

Optimization of Lutein Recovery from Tetraselmis suecica by Response Surface Methodology

  • Kang Hyun Lee,
  • Ye Won Jang,
  • Hansol Kim,
  • Jang-Seu Ki and
  • Hah Young Yoo

28 January 2021

Microalgae have been attracting attention as feedstock for biorefinery because they have various advantages, such as carbon fixation, high growth rate and high energy yield. The bioactive compounds and lutein contained in microalgae are known to be b...

  • Article
  • Open Access
43 Citations
8,076 Views
9 Pages

13 November 2012

Response surface methodology (RSM) was employed to optimize the extracellular lipase production by Burkholderia sp. HL-10. Preliminary tests showed that olive oil, tryptone and Tween-80 exhibited significant effects on the lipase production. The opti...

  • Article
  • Open Access
1,683 Views
27 Pages

Optimization of the Archimedean Spiral Hydrokinetic Turbine Design Using Response Surface Methodology

  • Juan Rengifo,
  • Laura Velásquez,
  • Edwin Chica and
  • Ainhoa Rubio-Clemente

21 July 2025

This research investigates enhancing the performance of an Archimedes screw-type hydrokinetic turbine (ASHT). A 3D transient computational model employing the six degrees of freedom (6-DOF) methodology within the ANSYS Fluent software 2022 R1, was se...

  • Article
  • Open Access
24 Citations
4,920 Views
16 Pages

Extraction Optimization of Mucilage from Seeds of Mimosa pudica by Response Surface Methodology

  • Syed Nasir Abbas Bukhari,
  • Arshad Ali,
  • Muhammad Ajaz Hussain,
  • Muhammad Tayyab,
  • Nasser F. Alotaibi,
  • Mervat A. Elsherif,
  • Kashaf Junaid and
  • Hasan Ejaz

6 May 2022

Mimosa pudica seed mucilage (MPM) is composed of glucuronoxylan, which is a swellable, pH-responsive and non-toxic biomaterial. Herein, we aimed to extract MPM from M. pudica seeds (MP seeds) to ascertain optimization of extraction conditions to get...

  • Article
  • Open Access
5 Citations
8,677 Views
11 Pages

Ecofriendly Ultrasonic Rust Removal: An Empirical Optimization Based on Response Surface Methodology

  • Lijie Zhang,
  • Bing He,
  • Shengnan Wang,
  • Guangcun Wang and
  • Xiaoming Yuan

16 September 2021

This study shows that the hard-to-remove rust layer on the guide sleeve surface of a used cylinder can be removed using a specially developed, environmentally friendly formula for cleaning rust. Furthermore, we studied the rust removal technology tha...

  • Article
  • Open Access
9 Citations
3,741 Views
14 Pages

Medium Optimization for GA4 Production by Gibberella fujikuroi Using Response Surface Methodology

  • Bingxuan Wang,
  • Kainan Yin,
  • Choufei Wu,
  • Liang Wang,
  • Lianghong Yin and
  • Haiping Lin

Gibberellin is an important plant growth regulator that has been widely used in agricultural production with great market prospects. However, the low yield from Gibberella fujikuroi restricts its application. To improve the production of gibberellin...

  • Article
  • Open Access
12 Citations
2,333 Views
16 Pages

Multiobjective Collaborative Optimization of Argon Bottom Blowing in a Ladle Furnace Using Response Surface Methodology

  • Zicheng Xin,
  • Jiankun Sun,
  • Jiangshan Zhang,
  • Bingchang He,
  • Junguo Zhang and
  • Qing Liu

26 July 2022

In order to consider both the refining efficiency of the ladle furnace (LF) and the quality of molten steel, the water model experiment is carried out. In this study, the single factor analysis, central composite design principle, response surface me...

  • Article
  • Open Access
83 Citations
11,026 Views
13 Pages

Optimization of Medium Using Response Surface Methodology for Lipid Production by Scenedesmus sp.

  • Fangfang Yang,
  • Lijuan Long,
  • Xiumei Sun,
  • Hualian Wu,
  • Tao Li and
  • Wenzhou Xiang

6 March 2014

Lipid production is an important indicator for assessing microalgal species for biodiesel production. In this work, the effects of medium composition on lipid production by Scenedesmus sp. were investigated using the response surface methodology. The...

  • Article
  • Open Access
5 Citations
2,332 Views
12 Pages

21 December 2020

Polymer optical fibers (POFs) were used for preparing side-emitting polymer optical fibers (SPOFs), which were processed with acetone and n-hexane combined in selected proportions by a solvent treatment method. The effects of the volume ratio of acet...

  • Feature Paper
  • Article
  • Open Access
11 Citations
2,752 Views
19 Pages

8 February 2022

In this study, Response Surface Methodology (RSM) and multi-objective genetic algorithm were used to obtain optimum parameters of the channels with frustum of a cone with better flow and heat transfer performance. Central composite face-centered desi...

  • Article
  • Open Access
19 Citations
6,531 Views
12 Pages

The main purpose of this study was to optimize the preparation of lysozyme nanoliposomes using response surface methodology and measure their stability. The stabilities of lysozyme nanoliposomes in simulated gastrointestinal fluid (SGF), simulated in...

  • Article
  • Open Access
1,844 Views
13 Pages

3 August 2023

In order to reduce the production cost of the methane carbon dioxide reforming reaction, and improve its actual production efficiency, in this paper, the optimal working parameters of the methane carbon dioxide reforming reaction are studied. The inf...

  • Article
  • Open Access
1,280 Views
22 Pages

Ship pipeline selection, as a crucial component of ship pipeline design, is often a time-consuming process due to its high complexity. In this study, the response surface methodology combined with the multi-objective particle swarm optimization algor...

  • Article
  • Open Access
4 Citations
3,307 Views
23 Pages

Optimization of Autoclave Reactors to Improve Bearing Life Using the Taguchi Method and the Response Surface Methodology

  • Farghani Fariz,
  • Brijesh Patel,
  • Hsien-Cheng Chiu,
  • Shih-Jie Pan,
  • Cheng-Liang Chen,
  • Hao-Yeh Lee and
  • Po Ting Lin

10 November 2023

Plastic pervasiveness in daily life has increased in tandem with population growth. Ethylene–vinyl acetate (EVA) is emerging as a popular compound for manufacturing plastic, which is obtained from ethylene and vinyl acetate synthesis. EVA is pr...

  • Article
  • Open Access
5 Citations
3,057 Views
16 Pages

Structural Design and Optimization of Separated Air-Rib Tents Based on Response Surface Methodology

  • Ying Liu,
  • Yi Ru,
  • Feng Li,
  • Lei Zheng,
  • Jun Zhang,
  • Xiaoyang Chen and
  • Shengchao Liang

21 December 2022

Air-rib tents are widely used because they are lightweight and site adaptable, but the large deformation of these tents reduces their effective space. It is important to reduce the displacement of the air-rib tent by parameter optimization. The influ...

  • Article
  • Open Access
1 Citations
941 Views
19 Pages

6 August 2025

Foam cement, as a building insulation material, encounters a major problem in practical application, which is the difficulty in achieving a balance between its strength and insulation performance. To achieve multi-objective optimization of foamed cem...

  • Article
  • Open Access
554 Views
13 Pages

Parametric Optimization of a Cross-Beam Glulam Floor System Using Response Surface Methodology

  • Oleksandr Gilodo,
  • Andrii Arsirii,
  • Sergii Kroviakov and
  • Oleksandr Gimanov

Cross-beam glued-laminated timber (glulam) floor systems offer material efficiency but pose a complex design challenge due to three-dimensional (3D) load interactions, and systematic optimization guidelines are lacking. This study implements a parame...

  • Article
  • Open Access
16 Citations
4,279 Views
15 Pages

Optimization of Osmotic Dehydration of Autumn Olive Berries Using Response Surface Methodology

  • Mohamed Ghellam,
  • Oscar Zannou,
  • Hojjat Pashazadeh,
  • Charis M. Galanakis,
  • Turki M. S. Aldawoud,
  • Salam A. Ibrahim and
  • Ilkay Koca

13 May 2021

Autumn olive fruits are a rich source of nutrients and functional compounds, making them functional foods against many diseases and cancers. To increase the consumption, its processing, and its transformation into new products would help spread them...

  • Article
  • Open Access
3 Citations
1,705 Views
18 Pages

14 April 2025

The parameters of Low-Impact Development (LID) facilities significantly influence their operational performance and runoff control effectiveness at the site. Despite extensive research on LID effectiveness, limited studies have focused on optimizing...

  • Article
  • Open Access
13 Citations
3,632 Views
16 Pages

12 October 2019

In this paper, in view of the low efficiency of the traditional finite element method (FEM), which has been widely used in the insulation design of power transformers, the response surface methodology (RSM) is proposed to optimize the insulation stru...

  • Article
  • Open Access
5 Citations
6,380 Views
11 Pages

Streptomyces thermoviolaceus NT1, an endophytic isolate, was studied for optimization of granaticinic acid production. It is an antimicrobial metabolite active against even drug resistant bacteria. Different media, optimum glucose concentration, init...

  • Article
  • Open Access
5 Citations
3,770 Views
27 Pages

8 February 2020

In this paper, a statistical analysis with response surface methodology (RSM) has been used to investigate and optimize process variables for the greener synthesis of chloromethyl ethylene carbonate (CMEC) by carbon dioxide (CO2) and epichlorohydrin...

  • Article
  • Open Access
21 Citations
2,843 Views
20 Pages

27 May 2024

Efficiently managing multiple process parameters is critical for achieving optimal performance in additive manufacturing. This study investigates the relationship between eight key parameters in fused deposition modeling (FDM) and their impact on res...

  • Article
  • Open Access
7 Citations
2,413 Views
15 Pages

23 June 2021

The present research aimed to investigate the effect of working parameters on the electrospinning of niobium–tungsten oxide nanofibers and optimize the process using central composite design (CCD) based on the response surface methodology (RSM). An e...

  • Article
  • Open Access
15 Citations
4,326 Views
16 Pages

9 August 2023

Hybrid microwave–hot air (MW–HA) drying of sweet potatoes was optimized using a face-centered central composite design (FCCCD) with response surface methodology through the desirability function. The independent variables were drying temp...

  • Article
  • Open Access
1 Citations
1,873 Views
13 Pages

20 December 2023

The recovery of valuable compounds like phenolic compounds and sugars from grape marc extracts implies different steps, including clarification. In this study, a response surface methodology (RSM) was used as a statistical tool to study the effects o...

  • Article
  • Open Access
7 Citations
2,252 Views
20 Pages

3 October 2022

This study investigated the sealing performance of the multistage liquid-sealing impellers of a turbopump. To achieve this purpose, the influence of each structural parameter in the impeller on the pressurization coefficient φ2 and the leakage fl...

  • Article
  • Open Access
12 Citations
3,662 Views
16 Pages

Heterotrophic and Photoautotrophic Media Optimization Using Response Surface Methodology for the Novel Microalga Chlorococcum amblystomatis

  • Nádia Correia,
  • Hugo Pereira,
  • Peter S. C. Schulze,
  • Monya M. Costa,
  • Gonçalo E. Santo,
  • Inês Guerra,
  • Mafalda Trovão,
  • Ana Barros,
  • Helena Cardoso and
  • João Varela
  • + 2 authors

6 February 2023

The nutritional requirements of novel microalgal strains are key for their effective cultivation and metabolite content. Therefore, the optimization of heterotrophic and photoautotrophic culture media is crucial for novel Chlorococcum amblystomatis g...

  • Article
  • Open Access
1 Citations
927 Views
17 Pages

21 May 2025

To advance the optimization of engineering parameters in in-seam borehole predrainage technology, this study developed a comprehensive analytical framework integrating theoretical modeling, numerical simulation, and field validation. Taking Pingdings...

  • Article
  • Open Access
4 Citations
1,431 Views
13 Pages

Optimization of Antifungal Properties of Hop Cone Carbon Dioxide Extracts Based on Response Surface Methodology

  • Katarzyna Tyśkiewicz,
  • Renata Tyśkiewicz,
  • Marcin Konkol,
  • Marcin Gruba and
  • Rafał Kowalski

Response surface methodology (RSM) was employed to optimize the process parameters of the supercritical carbon dioxide extraction of hop cones in terms of their antifungal properties against Fusarium culmorum and Aspergillus niger. The effects of tem...

  • Article
  • Open Access
13 Citations
10,087 Views
17 Pages

Optimization of Baker’s Yeast Production on Date Extract Using Response Surface Methodology (RSM)

  • Mounira Kara Ali,
  • Nawel Outili,
  • Asma Ait Kaki,
  • Radia Cherfia,
  • Sara Benhassine,
  • Akila Benaissa and
  • Noreddine Kacem Chaouche

7 August 2017

This work aims to study the production of the biomass of S. cerevisiae on an optimized medium using date extract as the only carbon source in order to obtain a good yield of the biomass. The biomass production was carried out according to the central...

  • Article
  • Open Access
889 Views
14 Pages

Optimization of Injection Strategy for CH4/Diesel Dual-Fuel Engine Using Response Surface Methodology

  • Sarah Ouchikh,
  • Mohand Said Lounici,
  • Khaled Loubar and
  • Mohand Tazerout

20 April 2025

Dual-fuel combustion technology allows for lower emissions of particulate matter (PM) and nitrogen oxide (NOx). However, under low load conditions, this mode of combustion has large amounts of emissions of carbon monoxide (CO) and unburned hydrocarbo...

  • Article
  • Open Access
3 Citations
1,553 Views
11 Pages

16 May 2024

Using a simple acid-base neutralization method, a Ch-PW solid catalyst was synthesized by mixing choline hydroxide (ChOH) and phosphotungstic acid (HPW) at a 2:1 molar ratio in an aqueous solution. This catalyst was combined with a 20 wt.% potassium...

  • Article
  • Open Access
684 Views
20 Pages

27 July 2025

Cable force distribution in cable-stayed bridges critically impacts structural safety and efficiency, yet traditional optimization methods struggle with unconventional designs due to nonlinear mechanics and computational inefficiency. This study prop...

  • Article
  • Open Access
749 Views
20 Pages

AI-Assisted Response Surface Methodology for Growth Optimization and Industrial Applicability Evaluation of the Diatom Gedaniella flavovirens GFTA21

  • Eun Song Kim,
  • Soo Jeong Lee,
  • Jung A Lee,
  • Sung Min An,
  • Hyun-Ju Hwang,
  • Bum Soo Park,
  • Hae-Won Lee,
  • Cheol-Ho Pan,
  • Daekyung Kim and
  • Kichul Cho

Although AI-mediated approaches provide promising support for bioengineering using training datasets, their application in microalgal research remains limited. In this study, ChatGPT-4.0, an easily accessible AI model, was employed to optimize cultur...

  • Article
  • Open Access
17 Citations
4,938 Views
11 Pages

27 February 2020

In this work, the response surface methodology was used to optimize the process parameters of gallic acid adsorption on magnetic ion exchange (MIEX) resin. Based on Box-Behnken Design, a quadratic polynomial model equation including solution pH, gall...

  • Communication
  • Open Access
9 Citations
3,052 Views
10 Pages

Optimization of Enhanced Ultrafiltration Conditions for Cd with Mixed Biosurfactants Using the Box-Behnken Response Surface Methodology

  • Tian Chai,
  • Huizhi Yan,
  • Zhibin Zhang,
  • Min Xu,
  • Yicheng Wu,
  • Lei Jin,
  • Guohe Huang and
  • Haiyan Fu

28 February 2019

A mixture of the environmentally friendly biosurfactants rhamnolipids and sophorolipids was used as a source of micelles in this study. The Box-Behnken design and response surface methodology was used to investigate the influence of factors on micell...

  • Article
  • Open Access
13 Citations
4,857 Views
12 Pages

Statistical Modeling and Performance Optimization of a Two-Chamber Microbial Fuel Cell by Response Surface Methodology

  • Muhammad Nihal Naseer,
  • Asad A. Zaidi,
  • Hamdullah Khan,
  • Sagar Kumar,
  • Muhammad Taha bin Owais,
  • Yasmin Abdul Wahab,
  • Kingshuk Dutta,
  • Juhana Jaafar,
  • Nor Aliya Hamizi and
  • Hussein Alrobei
  • + 3 authors

1 October 2021

Microbial fuel cell, as a promising technology for simultaneous power production and waste treatment, has received a great deal of attention in recent years; however, generation of a relatively low power density is the main limitation towards its com...

  • Article
  • Open Access
28 Citations
7,592 Views
13 Pages

4 May 2012

Water-extracted mycelial polysaccharide (WPS) from the endophytic fungus Fusarium oxysporum Dzf17 isolated from Dioscorea zingiberensis was found to be an efficient elicitor to enhance diosgenin accumulation in D. zingigerensis cultures, and also dem...

  • Article
  • Open Access
16 Citations
4,298 Views
18 Pages

Response Surface Methodology Routed Optimization of Performance of Hydroxy Gas Enriched Diesel Fuel in Compression Ignition Engines

  • Muhammad Usman,
  • Saifuddin Nomanbhay,
  • Mei Yin Ong,
  • Muhammad Wajid Saleem,
  • Muneeb Irshad,
  • Zain Ul Hassan,
  • Fahid Riaz,
  • Muhammad Haris Shah,
  • Muhammad Abdul Qyyum and
  • Pau Loke Show
  • + 1 author

1 August 2021

In this study, the response surface methodology (RSM) optimization technique was employed for investigating the impact of hydroxy gas (HHO) enriched diesel on performance, acoustics, smoke and exhaust gas emissions of the compression ignition (CI) en...

  • Article
  • Open Access
5 Citations
3,548 Views
21 Pages

17 November 2024

The work presents an analysis of the Gorlov helical turbine (GHT) design using both computational fluid dynamics (CFD) simulations and response surface methodology (RSM). The RSM method was applied to investigate the impact of three geometric factors...

  • Article
  • Open Access
9 Citations
2,411 Views
12 Pages

Modeling and Optimization of the Adsorption of Cr (VI) in a Chitosan-Resole Aerogel Using Response Surface Methodology

  • Jean Flores-Gómez,
  • Victor Hugo Romero-Arellano,
  • Milton Vazquez-Lepe,
  • Álvaro de Jesús Martínez-Gómez and
  • Juan Morales-Rivera

4 March 2023

In this paper, a model for Cr (VI) removal and optimization was made using a novel aerogel material, chitosan-resole CS/R aerogel, where a freeze-drying and final thermal treatment was employed to fabricate the aerogel. This processing ensures a netw...

  • Article
  • Open Access
10 Citations
5,465 Views
18 Pages

Optimization of the Fermentation Conditions for Brewing Yeast Biomass Production Using the Response Surface Methodology and Taguchi Technique

  • Iuliana Diana Bărbulescu,
  • Mihaela Violeta Ghica,
  • Mihaela Begea,
  • Mădălina Georgiana Albu Kaya,
  • Răzvan Ionuț Teodorescu,
  • Lăcrămioara Popa,
  • Simona Ioana Mărculescu,
  • Alexandru Ionuț Cîrîc,
  • Corina Dumitrache and
  • Cristina-Elena Dinu-Pîrvu
  • + 2 authors

9 December 2021

Yeast (including brewing yeast) and yeast-based preparations derived from bioprocesses or agroindustrial byproducts represent valuable feed additives and ingredients for ruminants. The optimization of brewing yeast biotechnological processing through...

  • Article
  • Open Access
16 Citations
3,847 Views
13 Pages

Application of Response Surface Methodology for Optimization of Nanosized Zinc Oxide Synthesis Conditions by Electrospinning Technique

  • Aizhan Rakhmanova,
  • Sandugash Kalybekkyzy,
  • Baktiyar Soltabayev,
  • Aiman Bissenbay,
  • Nazym Kassenova,
  • Zhumabay Bakenov and
  • Almagul Mentbayeva

18 May 2022

Zinc oxide (ZnO) is a well-known semiconductor material due to its excellent electrical, mechanical, and unique optical properties. ZnO nanoparticles are widely used for the industrial-scale manufacture of microelectronic and optoelectronic devices,...

  • Article
  • Open Access
1 Citations
878 Views
24 Pages

Hybrid Laser Cleaning of Carbon Deposits on N52B30 Engine Piston Crowns: Multi-Objective Optimization via Response Surface Methodology

  • Yishun Su,
  • Liang Wang,
  • Zhehe Yao,
  • Qunli Zhang,
  • Zhijun Chen,
  • Jiawei Duan,
  • Tingqing Ye and
  • Jianhua Yao

1 August 2025

Carbon deposits on the crown of engine pistons can markedly reduce combustion efficiency and shorten service life. Conventional cleaning techniques often fail to simultaneously ensure a high carbon removal efficiency and maintain optimal surface inte...

  • Article
  • Open Access
929 Views
23 Pages

31 July 2025

To address the issues of hydrogen embrittlement, creep, and fatigue that commonly occur in the welds of hydrogen production reactor operating under hydrogen exposure, high temperature and high pressure, this study proposes adding Si and Mo as reinfor...

  • Article
  • Open Access
3 Citations
2,476 Views
24 Pages

26 July 2024

The construction industry’s high energy consumption and carbon emissions negatively impact the ecological environment; large-scale construction projects consume much energy and emit a significant amount of CO2 into the atmosphere. Statistics sh...

  • Communication
  • Open Access
300 Views
18 Pages

28 November 2025

This study aimed to establish the optimal mix proportions for eco-friendly lightweight boards based on Ground Granulated Blast-furnace Slag (GGBFS) and waste rock wool using Response Surface Methodology (RSM). The investigation focused on optimizing...

  • Article
  • Open Access
15 Citations
4,957 Views
15 Pages

Osmotic distillation (OD) was implemented at laboratory scale to concentrate a red fruit juice produced from a blend of blood orange, prickly pear, and pomegranate juice. The raw juice was clarified by microfiltration and then concentrated by using a...

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