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2,125 Results Found

  • Article
  • Open Access
47 Citations
6,727 Views
14 Pages

Radiomics and Delta-Radiomics Signatures to Predict Response and Survival in Patients with Non-Small-Cell Lung Cancer Treated with Immune Checkpoint Inhibitors

  • François Cousin,
  • Thomas Louis,
  • Sophie Dheur,
  • Frank Aboubakar,
  • Benoit Ghaye,
  • Mariaelena Occhipinti,
  • Wim Vos,
  • Fabio Bottari,
  • Astrid Paulus and
  • Roland Hustinx
  • + 4 authors

25 March 2023

The aim of our study was to determine the potential role of CT-based radiomics in predicting treatment response and survival in patients with advanced NSCLC treated with immune checkpoint inhibitors. We retrospectively included 188 patients with NSCL...

(This article belongs to the Topic Cancer Immunity and Immunotherapy: Early Detection, Diagnosis, Systemic Treatments, Novel Biomarkers, and Resistance Mechanisms)
  • Feature Paper
  • Review
  • Open Access
81 Citations
8,550 Views
20 Pages

Radiomics in Lung Diseases Imaging: State-of-the-Art for Clinicians

  • Anne-Noëlle Frix,
  • François Cousin,
  • Turkey Refaee,
  • Fabio Bottari,
  • Akshayaa Vaidyanathan,
  • Colin Desir,
  • Wim Vos,
  • Sean Walsh,
  • Mariaelena Occhipinti and
  • Julien Guiot
  • + 6 authors

25 June 2021

Artificial intelligence (AI) has increasingly been serving the field of radiology over the last 50 years. As modern medicine is evolving towards precision medicine, offering personalized patient care and treatment, the requirement for robust imaging...

(This article belongs to the Section Omics/Informatics)
  • Systematic Review
  • Open Access
13 Citations
3,687 Views
13 Pages

Radiomics Analysis for Multiple Myeloma: A Systematic Review with Radiomics Quality Scoring

  • Michail E. Klontzas,
  • Matthaios Triantafyllou,
  • Dimitrios Leventis,
  • Emmanouil Koltsakis,
  • Georgios Kalarakis,
  • Antonios Tzortzakakis and
  • Apostolos H. Karantanas

Multiple myeloma (MM) is one of the most common hematological malignancies affecting the bone marrow. Radiomics analysis has been employed in the literature in an attempt to evaluate the bone marrow of MM patients. This manuscript aimed to systematic...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Systematic Review
  • Open Access
9 Citations
2,876 Views
14 Pages

Advancing Pediatric Sarcomas through Radiomics: A Systematic Review and Prospective Assessment Using Radiomics Quality Score (RQS) and Methodological Radiomics Score (METRICS)

  • Gayane Aghakhanyan,
  • Tommaso Filidei,
  • Maria Febi,
  • Salvatore C. Fanni,
  • Andrea Marciano,
  • Roberto Francischello,
  • Francesca Pia Caputo,
  • Lorenzo Tumminello,
  • Dania Cioni and
  • Duccio Volterrani
  • + 1 author

Pediatric sarcomas, rare malignancies of mesenchymal origin, pose diagnostic and therapeutic challenges. In this review, we explore the role of radiomics in reshaping our understanding of pediatric sarcomas, emphasizing methodological considerations...

(This article belongs to the Special Issue Diagnostic and Clinical Application of Magnetic Resonance Imaging)
  • Article
  • Open Access
3 Citations
2,282 Views
12 Pages

Integrated Hyperparameter Optimization with Dimensionality Reduction and Clustering for Radiomics: A Bootstrapped Approach

  • S. J. Pawan,
  • Matthew Muellner,
  • Xiaomeng Lei,
  • Mihir Desai,
  • Bino Varghese,
  • Vinay Duddalwar and
  • Steven Y. Cen

Radiomics involves extracting quantitative features from medical images, resulting in high-dimensional data. Unsupervised clustering has been used to discover patterns in radiomic features, potentially yielding hidden biological insights. However, it...

  • Review
  • Open Access
24 Citations
4,698 Views
19 Pages

MRI-Based Radiomics in Bladder Cancer: A Systematic Review and Radiomics Quality Score Assessment

  • Bianca Boca,
  • Cosmin Caraiani,
  • Teodora Telecan,
  • Roxana Pintican,
  • Andrei Lebovici,
  • Iulia Andras,
  • Nicolae Crisan,
  • Alexandru Pavel,
  • Laura Diosan and
  • Mircea Marian Buruian
  • + 2 authors

(1): Background: With the recent introduction of vesical imaging reporting and data system (VI-RADS), magnetic resonance imaging (MRI) has become the main imaging method used for the preoperative local staging of bladder cancer (BCa). However, the VI...

(This article belongs to the Special Issue State of the Art of Abdominal Radiology)
  • Systematic Review
  • Open Access
20 Citations
3,398 Views
11 Pages

The Role of Radiomics in Salivary Gland Imaging: A Systematic Review and Radiomics Quality Assessment

  • Giacomo Aringhieri,
  • Salvatore Claudio Fanni,
  • Maria Febi,
  • Leonardo Colligiani,
  • Dania Cioni and
  • Emanuele Neri

1 December 2022

Background: Radiomics of salivary gland imaging can support clinical decisions in different clinical scenarios, such as tumors, radiation-induced xerostomia and sialadenitis. This review aims to evaluate the methodological quality of radiomics studie...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
9 Citations
2,761 Views
14 Pages

Utility of CT Radiomics and Delta Radiomics for Survival Evaluation in Locally Advanced Nasopharyngeal Carcinoma with Concurrent Chemoradiotherapy

  • Yen-Cho Huang,
  • Shih-Ming Huang,
  • Jih-Hsiang Yeh,
  • Tung-Chieh Chang,
  • Din-Li Tsan,
  • Chien-Yu Lin and
  • Shu-Ju Tu

Background: A high incidence rate of nasopharyngeal carcinoma (NPC) has been observed in Southeast Asia compared to other parts of the world. Radiomics is a computational tool to predict outcomes and may be used as a prognostic biomarker for advanced...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Systematic Review
  • Open Access
3 Citations
1,249 Views
18 Pages

6 January 2026

Background/Objectives: Hepatocellular carcinoma (HCC) immunotherapy provides limited clinical benefits, partly due to the lack of reliable efficacy biomarkers. Radiomics, which non-invasively analyzes tumor heterogeneity, shows promising potential fo...

(This article belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)
  • Review
  • Open Access
24 Citations
11,452 Views
33 Pages

Decoding Radiomics: A Step-by-Step Guide to Machine Learning Workflow in Hand-Crafted and Deep Learning Radiomics Studies

  • Maurizio Cè,
  • Marius Dumitru Chiriac,
  • Andrea Cozzi,
  • Laura Macrì,
  • Francesca Lucrezia Rabaiotti,
  • Giovanni Irmici,
  • Deborah Fazzini,
  • Gianpaolo Carrafiello and
  • Michaela Cellina

5 November 2024

Although radiomics research has experienced rapid growth in recent years, with numerous studies dedicated to the automated extraction of diagnostic and prognostic information from various imaging modalities, such as CT, PET, and MRI, only a small fra...

(This article belongs to the Special Issue Machine Learning in Radiomics: Opportunities and Challenges)
  • Article
  • Open Access
8 Citations
6,729 Views
18 Pages

Delta Radiomics and Tumor Size: A New Predictive Radiomics Model for Chemotherapy Response in Liver Metastases from Breast and Colorectal Cancer

  • Nicolò Gennaro,
  • Moataz Soliman,
  • Amir A. Borhani,
  • Linda Kelahan,
  • Hatice Savas,
  • Ryan Avery,
  • Kamal Subedi,
  • Tugce A. Trabzonlu,
  • Chase Krumpelman and
  • Yuri S. Velichko
  • + 7 authors

20 February 2025

Background/Objectives: Radiomic features exhibit a correlation with tumor size on pretreatment images. However, on post-treatment images, this association is influenced by treatment efficacy and varies between responders and non-responders. This stud...

(This article belongs to the Special Issue Imaging in Cancer Diagnosis)
  • Systematic Review
  • Open Access
16 Citations
6,329 Views
20 Pages

Radiomics in Oncological PET Imaging: A Systematic Review—Part 1, Supradiaphragmatic Cancers

  • David Morland,
  • Elizabeth Katherine Anna Triumbari,
  • Luca Boldrini,
  • Roberto Gatta,
  • Daniele Pizzuto and
  • Salvatore Annunziata

Radiomics is an upcoming field in nuclear oncology, both promising and technically challenging. To summarize the already undertaken work on supradiaphragmatic neoplasia and assess its quality, we performed a literature search in the PubMed database u...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
2 Citations
1,610 Views
14 Pages

Application of Radiomics in Predicting the Prognosis of Medulloblastoma in Children

  • Jiashu Chen,
  • Wei Yang,
  • Zesheng Ying,
  • Ping Yang,
  • Yuting Liang,
  • Chen Liang,
  • Baojin Shang,
  • Hong Zhang,
  • Yingjie Cai and
  • Ming Ge
  • + 3 authors

20 March 2025

Background and Purpose: Medulloblastoma (MB) represents the predominant intracranial neoplasm observed in pediatric populations, characterized by a five-year survival rate ranging from 60% to 80%. Anticipating the prognostic outcome of medulloblastom...

(This article belongs to the Section Pediatric Surgery)
  • Review
  • Open Access
144 Citations
30,239 Views
26 Pages

Radiomics and Its Feature Selection: A Review

  • Wenchao Zhang,
  • Yu Guo and
  • Qiyu Jin

27 September 2023

Medical imaging plays an indispensable role in evaluating, predicting, and monitoring a range of medical conditions. Radiomics, a specialized branch of medical imaging, utilizes quantitative features extracted from medical images to describe underlyi...

(This article belongs to the Section E: Life Sciences)
  • Review
  • Open Access
38 Citations
6,039 Views
20 Pages

Radiomics of Musculoskeletal Sarcomas: A Narrative Review

  • Cristiana Fanciullo,
  • Salvatore Gitto,
  • Eleonora Carlicchi,
  • Domenico Albano,
  • Carmelo Messina and
  • Luca Maria Sconfienza

13 February 2022

Bone and soft-tissue primary malignant tumors or sarcomas are a large, diverse group of mesenchymal-derived malignancies. They represent a model for intra- and intertumoral heterogeneities, making them particularly suitable for radiomics analyses. Ra...

(This article belongs to the Special Issue Radiomics and Texture Analysis in Medical Imaging)
  • Article
  • Open Access
46 Citations
8,235 Views
13 Pages

matRadiomics: A Novel and Complete Radiomics Framework, from Image Visualization to Predictive Model

  • Giovanni Pasini,
  • Fabiano Bini,
  • Giorgio Russo,
  • Albert Comelli,
  • Franco Marinozzi and
  • Alessandro Stefano

18 August 2022

Radiomics aims to support clinical decisions through its workflow, which is divided into: (i) target identification and segmentation, (ii) feature extraction, (iii) feature selection, and (iv) model fitting. Many radiomics tools were developed to ful...

(This article belongs to the Special Issue Radiomics and Texture Analysis in Medical Imaging)
  • Review
  • Open Access
53 Citations
6,971 Views
14 Pages

Radiomics Models for Predicting Microvascular Invasion in Hepatocellular Carcinoma: A Systematic Review and Radiomics Quality Score Assessment

  • Qiang Wang,
  • Changfeng Li,
  • Jiaxing Zhang,
  • Xiaojun Hu,
  • Yingfang Fan,
  • Kuansheng Ma,
  • Ernesto Sparrelid and
  • Torkel B. Brismar

22 November 2021

Preoperative prediction of microvascular invasion (MVI) is of importance in hepatocellular carcinoma (HCC) patient treatment management. Plenty of radiomics models for MVI prediction have been proposed. This study aimed to elucidate the role of radio...

(This article belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)
  • Review
  • Open Access
64 Citations
10,111 Views
9 Pages

Radiogenomics and Radiomics in Liver Cancers

  • Aman Saini,
  • Ilana Breen,
  • Yash Pershad,
  • Sailendra Naidu,
  • M. Grace Knuttinen,
  • Sadeer Alzubaidi,
  • Rahul Sheth,
  • Hassan Albadawi,
  • Malia Kuo and
  • Rahmi Oklu

Radiogenomics is a computational discipline that identifies correlations between cross-sectional imaging features and tissue-based molecular data. These imaging phenotypic correlations can then potentially be used to longitudinally and non-invasively...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
23 Citations
5,292 Views
16 Pages

Challenges in Glioblastoma Radiomics and the Path to Clinical Implementation

  • Philip Martin,
  • Lois Holloway,
  • Peter Metcalfe,
  • Eng-Siew Koh and
  • Caterina Brighi

12 August 2022

Radiomics is a field of medical imaging analysis that focuses on the extraction of many quantitative imaging features related to shape, intensity and texture. These features are incorporated into models designed to predict important clinical or biolo...

(This article belongs to the Collection Imaging Biomarker in Oncology)
  • Feature Paper
  • Review
  • Open Access
106 Citations
11,017 Views
21 Pages

Radiomics of Liver Metastases: A Systematic Review

  • Francesco Fiz,
  • Luca Viganò,
  • Nicolò Gennaro,
  • Guido Costa,
  • Ludovico La Bella,
  • Alexandra Boichuk,
  • Lara Cavinato,
  • Martina Sollini,
  • Letterio S. Politi and
  • Guido Torzilli
  • + 1 author

7 October 2020

Multidisciplinary management of patients with liver metastases (LM) requires a precision medicine approach, based on adequate profiling of tumor biology and robust biomarkers. Radiomics, defined as the high-throughput identification, analysis, and tr...

  • Review
  • Open Access
13 Citations
4,073 Views
22 Pages

Use of Radiomics in Characterizing Tumor Hypoxia

  • Mohan Huang,
  • Helen K. W. Law and
  • Shing Yau Tam

Tumor hypoxia involves limited oxygen supply within the tumor microenvironment and is closely associated with aggressiveness, metastasis, and resistance to common cancer treatment modalities such as chemotherapy and radiotherapy. Traditional methodol...

(This article belongs to the Section Molecular Genetics and Genomics)
  • Systematic Review
  • Open Access
13 Citations
6,094 Views
22 Pages

Radiomic Signatures Associated with CD8+ Tumour-Infiltrating Lymphocytes: A Systematic Review and Quality Assessment Study

  • Syafiq Ramlee,
  • David Hulse,
  • Kinga Bernatowicz,
  • Raquel Pérez-López,
  • Evis Sala and
  • Luigi Aloj

27 July 2022

The tumour immune microenvironment influences the efficacy of immune checkpoint inhibitors. Within this microenvironment are CD8-expressing tumour-infiltrating lymphocytes (CD8+ TILs), which are an important mediator and marker of anti-tumour respons...

(This article belongs to the Special Issue Immune Checkpoint Inhibitors in Cancer Therapy—How Can We Improve Clinical Benefits?)
  • Review
  • Open Access
64 Citations
8,662 Views
14 Pages

The Integration of Radiomics and Artificial Intelligence in Modern Medicine

  • Antonino Maniaci,
  • Salvatore Lavalle,
  • Caterina Gagliano,
  • Mario Lentini,
  • Edoardo Masiello,
  • Federica Parisi,
  • Giannicola Iannella,
  • Nicole Dalia Cilia,
  • Valerio Salerno and
  • Luigi La Via
  • + 1 author

1 October 2024

With profound effects on patient care, the role of artificial intelligence (AI) in radiomics has become a disruptive force in contemporary medicine. Radiomics, the quantitative feature extraction and analysis from medical images, offers useful imagin...

(This article belongs to the Section Radiobiology and Nuclear Medicine)
  • Article
  • Open Access
14 Citations
4,269 Views
12 Pages

Radiomics in PI-RADS 3 Multiparametric MRI for Prostate Cancer Identification: Literature Models Re-Implementation and Proposal of a Clinical–Radiological Model

  • Andrea Corsi,
  • Elisabetta De Bernardi,
  • Pietro Andrea Bonaffini,
  • Paolo Niccolò Franco,
  • Dario Nicoletta,
  • Roberto Simonini,
  • Davide Ippolito,
  • Giovanna Perugini,
  • Mariaelena Occhipinti and
  • Sandro Sironi
  • + 2 authors

26 October 2022

PI-RADS 3 prostate lesions clinical management is still debated, with high variability among different centers. Identifying clinically significant tumors among PI-RADS 3 is crucial. Radiomics applied to multiparametric MR (mpMR) seems promising. Neve...

(This article belongs to the Special Issue Prostate Cancer: Recent Advances in Diagnostics and Treatment Planning)
  • Feature Paper
  • Review
  • Open Access
58 Citations
8,563 Views
11 Pages

PET/CT Radiomics in Lung Cancer: An Overview

  • Francesco Bianconi,
  • Isabella Palumbo,
  • Angela Spanu,
  • Susanna Nuvoli,
  • Mario Luca Fravolini and
  • Barbara Palumbo

3 March 2020

Quantitative extraction of imaging features from medical scans (‘radiomics’) has attracted a lot of research attention in the last few years. The literature has consistently emphasized the potential use of radiomics for computer-assisted...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Systematic Review
  • Open Access
2 Citations
1,689 Views
27 Pages

Radiomics from Routine CT and PET/CT Imaging in Laryngeal Squamous Cell Carcinoma: A Systematic Review with Radiomics Quality Score Assessment

  • Amar Rajgor,
  • Terrenjit Gill,
  • Eric Aboagye,
  • Aileen Mill,
  • Stephen Rushton,
  • Boguslaw Obara and
  • David Winston Hamilton

13 January 2026

Background/Objectives: Radiomics, the high-throughput extraction of quantitative features from medical imaging, offers a promising method for identifying laryngeal cancer imaging biomarkers. We aim to systematically review the literature on radiomics...

(This article belongs to the Section Systematic Review or Meta-Analysis in Cancer Research)
  • Review
  • Open Access
26 Citations
5,560 Views
13 Pages

Radiomics for the Diagnosis and Differentiation of Pancreatic Cystic Lesions

  • Jorge D. Machicado,
  • Eugene J. Koay and
  • Somashekar G. Krishna

Radiomics, also known as quantitative imaging or texture analysis, involves extracting a large number of features traditionally unmeasured in conventional radiological cross-sectional images and converting them into mathematical models. This review d...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
10 Citations
4,227 Views
19 Pages

Automation Radiomics in Predicting Radiation Pneumonitis (RP)

  • Sotiris Raptis,
  • Vasiliki Softa,
  • Georgios Angelidis,
  • Christos Ilioudis and
  • Kiki Theodorou

6 July 2023

Radiomics has shown great promise in predicting various diseases. Researchers have previously attempted to include radiomics in their automated detection, diagnosis, and segmentation algorithms, taking these steps based on the promising outcomes of r...

  • Systematic Review
  • Open Access
33 Citations
5,862 Views
20 Pages

A Systematic Review of the Current Status and Quality of Radiomics for Glioma Differential Diagnosis

  • Valentina Brancato,
  • Marco Cerrone,
  • Marialuisa Lavitrano,
  • Marco Salvatore and
  • Carlo Cavaliere

31 May 2022

Radiomics is a promising tool that may increase the value of imaging in differential diagnosis (DDx) of glioma. However, implementation in clinical practice is still distant and concerns have been raised regarding the methodological quality of radiom...

(This article belongs to the Special Issue In Vivo Quantitative Imaging of Gliomas)
  • Review
  • Open Access
15 Citations
3,918 Views
10 Pages

Inflammatory bowel disease (IBD) is a global health concern that has been on the rise in recent years. In addition, imaging is the established method of care for detecting, diagnosing, planning treatment, and monitoring the progression of IBD. While...

(This article belongs to the Special Issue Advances in the Diagnosis of Gastrointestinal Diseases—2nd Edition)
  • Review
  • Open Access
26 Citations
4,223 Views
22 Pages

Radiomics in Action: Multimodal Synergies for Imaging Biomarkers

  • Everton Flaiban,
  • Kaan Orhan,
  • Bianca Costa Gonçalves,
  • Sérgio Lúcio Pereira de Castro Lopes and
  • Andre Luiz Ferreira Costa

Radiomics has recently begun as a transformative approach in medical imaging, shifting radiology from qualitative description to quantitative analysis. By extracting high-throughput features from CT (Computed Tomography), MRI (Magnetic Resonance Imag...

(This article belongs to the Special Issue Medical Imaging Analysis: Current and Future Trends)
  • Review
  • Open Access
15 Citations
5,979 Views
17 Pages

Radiomics in Lung Metastases: A Systematic Review

  • Michela Gabelloni,
  • Lorenzo Faggioni,
  • Roberta Fusco,
  • Igino Simonetti,
  • Federica De Muzio,
  • Giuliana Giacobbe,
  • Alessandra Borgheresi,
  • Federico Bruno,
  • Diletta Cozzi and
  • Vincenza Granata
  • + 6 authors

27 January 2023

Due to the rich vascularization and lymphatic drainage of the pulmonary tissue, lung metastases (LM) are not uncommon in patients with cancer. Radiomics is an active research field aimed at the extraction of quantitative data from diagnostic images,...

(This article belongs to the Section Omics/Informatics)
  • Systematic Review
  • Open Access
9 Citations
3,355 Views
14 Pages

Diagnostic Accuracy of Radiomics in the Early Detection of Pancreatic Cancer: A Systematic Review and Qualitative Assessment Using the Methodological Radiomics Score (METRICS)

  • María Estefanía Renjifo-Correa,
  • Salvatore Claudio Fanni,
  • Luis A. Bustamante-Cristancho,
  • Maria Emanuela Cuibari,
  • Gayane Aghakhanyan,
  • Lorenzo Faggioni,
  • Emanuele Neri and
  • Dania Cioni

26 February 2025

Background/Objectives: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal malignancy with increasing incidence and low survival rate, primarily due to the late detection of the disease. Radiomics has demonstrated its utility in recog...

(This article belongs to the Special Issue Multimodality Imaging for More Precise Radiotherapy)
  • Review
  • Open Access
64 Citations
12,670 Views
22 Pages

Harmonization Strategies in Multicenter MRI-Based Radiomics

  • Elisavet Stamoulou,
  • Constantinos Spanakis,
  • Georgios C. Manikis,
  • Georgia Karanasiou,
  • Grigoris Grigoriadis,
  • Theodoros Foukakis,
  • Manolis Tsiknakis,
  • Dimitrios I. Fotiadis and
  • Kostas Marias

7 November 2022

Radiomics analysis is a powerful tool aiming to provide diagnostic and prognostic patient information directly from images that are decoded into handcrafted features, comprising descriptors of shape, size and textural patterns. Although radiomics is...

(This article belongs to the Special Issue Radiomics and Texture Analysis in Medical Imaging)
  • Systematic Review
  • Open Access
10 Citations
4,594 Views
19 Pages

Radiomics in Oncological PET Imaging: A Systematic Review—Part 2, Infradiaphragmatic Cancers, Blood Malignancies, Melanoma and Musculoskeletal Cancers

  • David Morland,
  • Elizabeth Katherine Anna Triumbari,
  • Luca Boldrini,
  • Roberto Gatta,
  • Daniele Pizzuto and
  • Salvatore Annunziata

The objective of this review was to summarize published radiomics studies dealing with infradiaphragmatic cancers, blood malignancies, melanoma, and musculoskeletal cancers, and assess their quality. PubMed database was searched from January 1990 to...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
21 Citations
4,179 Views
17 Pages

Differentiation of Hepatocellular Carcinoma from Intrahepatic Cholangiocarcinoma through MRI Radiomics

  • Ning Liu,
  • Yaokun Wu,
  • Yunyun Tao,
  • Jing Zheng,
  • Xiaohua Huang,
  • Lin Yang and
  • Xiaoming Zhang

11 November 2023

The purpose of this study was to investigate the efficacy of magnetic resonance imaging (MRI) radiomics in differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICC). The clinical and MRI data of 129 pathologically conf...

(This article belongs to the Special Issue New Insights of Management of Hepatocellular Carcinoma)
  • Review
  • Open Access
22 Citations
4,531 Views
13 Pages

Radiomics in Cardiac Computed Tomography

  • Isabelle Ayx,
  • Matthias F. Froelich,
  • Stefan Baumann,
  • Theano Papavassiliu and
  • Stefan O. Schoenberg

In recent years, there has been an increasing recognition of coronary computed tomographic angiography (CCTA) and gated non-contrast cardiac CT in the workup of coronary artery disease in patients with low and intermediate pretest probability, throug...

(This article belongs to the Special Issue Coronary Artery Disease Assessment and Pre-procedural Planning Using Cardiac Computed Tomography)
  • Review
  • Open Access
8 Citations
1,265 Views
30 Pages

Radiomics enables quantitative medical image analysis by converting imaging data into structured, high-dimensional feature representations for predictive modeling. Despite methodological developments and encouraging retrospective results, radiomics c...

(This article belongs to the Section Medical Imaging)
  • Review
  • Open Access
65 Citations
8,490 Views
18 Pages

How Radiomics Can Improve Breast Cancer Diagnosis and Treatment

  • Filippo Pesapane,
  • Paolo De Marco,
  • Anna Rapino,
  • Eleonora Lombardo,
  • Luca Nicosia,
  • Priyan Tantrige,
  • Anna Rotili,
  • Anna Carla Bozzini,
  • Silvia Penco and
  • Enrico Cassano
  • + 9 authors

9 February 2023

Recent technological advances in the field of artificial intelligence hold promise in addressing medical challenges in breast cancer care, such as early diagnosis, cancer subtype determination and molecular profiling, prediction of lymph node metasta...

(This article belongs to the Special Issue Artificial Intelligence in Radiology: Present and Future Perspectives)
  • Review
  • Open Access
11 Citations
3,464 Views
11 Pages

Radiomics, a Promising New Discipline: Example of Hepatocellular Carcinoma

  • Thomas Lévi-Strauss,
  • Bettina Tortorici,
  • Olivier Lopez,
  • Philippe Viau,
  • Dann J. Ouizeman,
  • Baptiste Schall,
  • Xavier Adhoute,
  • Olivier Humbert,
  • Patrick Chevallier and
  • Rodolphe Anty
  • + 2 authors

Radiomics is a discipline that involves studying medical images through their digital data. Using “artificial intelligence” algorithms, radiomics utilizes quantitative and high-throughput analysis of an image’s textural richness to...

(This article belongs to the Special Issue Recent Advances in Liver Diseases Diagnosis)
  • Review
  • Open Access
15 Citations
4,695 Views
20 Pages

Artificial Intelligence and Radiomics in Cholangiocarcinoma: A Comprehensive Review

  • Marta Zerunian,
  • Tiziano Polidori,
  • Federica Palmeri,
  • Stefano Nardacci,
  • Antonella Del Gaudio,
  • Benedetta Masci,
  • Giuseppe Tremamunno,
  • Michela Polici,
  • Domenico De Santis and
  • Damiano Caruso
  • + 2 authors

Cholangiocarcinoma (CCA) is a malignant biliary system tumor and the second most common primary hepatic neoplasm, following hepatocellular carcinoma. CCA still has an extremely high unfavorable prognosis, regardless of type and location, and complete...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
2,105 Views
15 Pages

Predicting Stroke Etiology with Radiomics: A Retrospective Study

  • Jacobo Porto-Álvarez,
  • Antonio Jesús Mosqueira Martínez,
  • Javier Martínez Fernández,
  • José L. Taboada Arcos,
  • Miguel Blanco Ulla,
  • José M. Pumar,
  • María Santamaría,
  • Emilio Rodríguez Castro,
  • Ramón Iglesias Rey and
  • Miguel Souto Bayarri
  • + 4 authors

Background/Objectives: The composition of the thrombus is not taken into account in the etiology determination of patients with acute ischemic stroke (AIS); however, it varies depending on the origin of the thrombus, as atherothrombotic thrombi conta...

  • Article
  • Open Access
21 Citations
4,429 Views
14 Pages

This study aimed to establish and validate a radiomics nomogram using the radiomics score (rad-score) based on multiregional diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) features combined with clinical factors for evaluat...

(This article belongs to the Special Issue Advancement in Breast Diagnostic and Interventional Radiology)
  • Review
  • Open Access
1 Citations
3,448 Views
22 Pages

Radiomics in Gynaecological Imaging: A State-of-the-Art Review

  • Paolo Niccolò Franco,
  • Federica Vernuccio,
  • Cesare Maino,
  • Roberto Cannella,
  • Milagros Otero-García and
  • Davide Ippolito

29 October 2023

Radiomics is an emerging field of research based on extracting mathematical descriptive features from medical images with the aim of improving diagnostic performance and providing increasing support to clinical decisions. In recent years, a number of...

(This article belongs to the Section Applied Biosciences and Bioengineering)
  • Article
  • Open Access
4 Citations
3,607 Views
13 Pages

Development and Implementation of an Innovative Framework for Automated Radiomics Analysis in Neuroimaging

  • Chiara Camastra,
  • Giovanni Pasini,
  • Alessandro Stefano,
  • Giorgio Russo,
  • Basilio Vescio,
  • Fabiano Bini,
  • Franco Marinozzi and
  • Antonio Augimeri

Radiomics represents an innovative approach to medical image analysis, enabling comprehensive quantitative evaluation of radiological images through advanced image processing and Machine or Deep Learning algorithms. This technique uncovers intricate...

(This article belongs to the Topic Applications in Image Analysis and Pattern Recognition)
  • Article
  • Open Access
3 Citations
1,592 Views
13 Pages

Application of Radiomics for Differentiating Lung Neuroendocrine Neoplasms

  • Aleksandr Borisov,
  • David Karelidze,
  • Mikhail Ivannikov,
  • Elina Shakhvalieva,
  • Peri Sultanova,
  • Kirill Arzamasov,
  • Nikolai Nudnov and
  • Yuriy Vasilev

Background/Objectives: Lung neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors requiring accurate differentiation from non-small cell lung cancer (NSCLC) for effective treatment. Conventional computed tomography (CT) lacks pathognomo...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Systematic Review
  • Open Access
24 Citations
5,234 Views
45 Pages

Systematic Review on the Association of Radiomics with Tumor Biological Endpoints

  • Agustina La Greca Saint-Esteven,
  • Diem Vuong,
  • Fabienne Tschanz,
  • Janita E. van Timmeren,
  • Riccardo Dal Bello,
  • Verena Waller,
  • Martin Pruschy,
  • Matthias Guckenberger and
  • Stephanie Tanadini-Lang

16 June 2021

Radiomics supposes an alternative non-invasive tumor characterization tool, which has experienced increased interest with the advent of more powerful computers and more sophisticated machine learning algorithms. Nonetheless, the incorporation of radi...

  • Review
  • Open Access
42 Citations
5,798 Views
10 Pages

Systematic Review, Meta-Analysis and Radiomics Quality Score Assessment of CT Radiomics-Based Models Predicting Tumor EGFR Mutation Status in Patients with Non-Small-Cell Lung Cancer

  • Mehdi Felfli,
  • Yan Liu,
  • Fadila Zerka,
  • Charles Voyton,
  • Alexandre Thinnes,
  • Sebastien Jacques,
  • Antoine Iannessi and
  • Sylvain Bodard

Assessment of the quality and current performance of computed tomography (CT) radiomics-based models in predicting epidermal growth factor receptor (EGFR) mutation status in patients with non-small-cell lung carcinoma (NSCLC). Two medical literature...

(This article belongs to the Section Molecular Oncology)
  • Review
  • Open Access
25 Citations
5,103 Views
12 Pages

Radiomics Analysis in Ovarian Cancer: A Narrative Review

  • Francesca Arezzo,
  • Vera Loizzi,
  • Daniele La Forgia,
  • Marco Moschetta,
  • Alberto Stefano Tagliafico,
  • Viviana Cataldo,
  • Adam Abdulwakil Kawosha,
  • Vincenzo Venerito,
  • Gerardo Cazzato and
  • Gennaro Cormio
  • + 3 authors

25 August 2021

Ovarian cancer (OC) is the second most common gynecological malignancy, accounting for about 14,000 deaths in 2020 in the US. The recognition of tools for proper screening, early diagnosis, and prognosis of OC is still lagging. The application of met...

(This article belongs to the Special Issue Artificial Intelligence and Radiomic Analysis in Medicine)
  • Perspective
  • Open Access
11 Citations
4,315 Views
19 Pages

29 August 2020

Processing and modeling medical images have traditionally represented complex tasks requiring multidisciplinary collaboration. The advent of radiomics has assigned a central role to quantitative data analytics targeting medical image features algorit...

(This article belongs to the Special Issue Radiomics and Cancers)

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