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68 Results Found

  • Article
  • Open Access
10 Citations
2,352 Views
13 Pages

Glaucoma represents a significant global contributor to blindness. Accurately segmenting the optic disc (OD) and optic cup (OC) to obtain precise CDR is essential for effective screening. However, existing convolutional neural network (CNN)-based seg...

  • Article
  • Open Access
10 Citations
2,446 Views
14 Pages

8 June 2022

Fundus segmentation is an important step in the diagnosis of ophthalmic diseases, especially glaucoma. A modified particle swarm optimization algorithm for optic disc segmentation is proposed, considering the fact that the current public fundus datas...

  • Article
  • Open Access
4 Citations
2,689 Views
17 Pages

An End-to-End Real-Time Lightweight Network for the Joint Segmentation of Optic Disc and Optic Cup on Fundus Images

  • Zhijie Liu,
  • Yuanqiong Chen,
  • Xiaohua Xiang,
  • Zhan Li,
  • Bolin Liao and
  • Jianfeng Li

16 November 2022

Glaucoma is the second-most-blinding eye disease in the world and accurate segmentation of the optic disc (OD) and optic cup (OC) is essential for the diagnosis of glaucoma. To solve the problems of poor real-time performance, high algorithm complexi...

  • Article
  • Open Access
18 Citations
9,432 Views
26 Pages

Glaucoma is a leading cause of irreversible vision loss that gradually damages the optic nerve. In ophthalmic fundus images, measurements of the cup to optic disc (CD) ratio, CD area ratio, neuroretinal rim to optic disc (RD) area ratio, and rim thic...

  • Article
  • Open Access
29 Citations
5,695 Views
17 Pages

11 October 2019

Glaucoma is a serious eye disease that can cause permanent blindness and is difficult to diagnose early. Optic disc (OD) and optic cup (OC) play a pivotal role in the screening of glaucoma. Therefore, accurate segmentation of OD and OC from fundus im...

  • Article
  • Open Access
1 Citations
1,947 Views
29 Pages

6 May 2025

Segmentation of the Optic Disc (OD) and Optic Cup (OC) boundaries in fundus images is a critical step for early glaucoma diagnosis, but accurate segmentation is challenging due to low boundary contrast and significant anatomical variability. To addre...

  • Article
  • Open Access
166 Citations
14,867 Views
19 Pages

Deep Learning for Optic Disc Segmentation and Glaucoma Diagnosis on Retinal Images

  • Syna Sreng,
  • Noppadol Maneerat,
  • Kazuhiko Hamamoto and
  • Khin Yadanar Win

17 July 2020

Glaucoma is a major global cause of blindness. As the symptoms of glaucoma appear, when the disease reaches an advanced stage, proper screening of glaucoma in the early stages is challenging. Therefore, regular glaucoma screening is essential and rec...

  • Article
  • Open Access
36 Citations
5,020 Views
13 Pages

30 July 2020

Medical image segmentation is an important part of medical image analysis. With the rapid development of convolutional neural networks in image processing, deep learning methods have achieved great success in the field of medical image processing. De...

  • Article
  • Open Access
8 Citations
2,920 Views
25 Pages

Multiple Preprocessing Hybrid Level Set Model for Optic Disc Segmentation in Fundus Images

  • Xiaozhong Xue,
  • Linni Wang,
  • Weiwei Du,
  • Yusuke Fujiwara and
  • Yahui Peng

13 September 2022

The accurate segmentation of the optic disc (OD) in fundus images is a crucial step for the analysis of many retinal diseases. However, because of problems such as vascular occlusion, parapapillary atrophy (PPA), and low contrast, accurate OD segment...

  • Article
  • Open Access
8 Citations
3,643 Views
23 Pages

12 June 2024

Glaucoma is a common eye disease that damages the optic nerve and leads to loss of vision. The disease shows few symptoms in the early stages, making its identification a complex task. To overcome the challenges associated with this task, this study...

  • Article
  • Open Access
11 Citations
8,133 Views
18 Pages

10 October 2019

Accurate optic disc (OD) and optic cup (OC) segmentation play a critical role in automatic glaucoma diagnosis. In this paper, we present an automatic segmentation technique regarding the OD and the OC for glaucoma assessment. First, the robust adapti...

  • Communication
  • Open Access
27 Citations
5,154 Views
14 Pages

Identifying the Edges of the Optic Cup and the Optic Disc in Glaucoma Patients by Segmentation

  • Srikanth Tadisetty,
  • Ranjith Chodavarapu,
  • Ruoming Jin,
  • Robert J. Clements and
  • Minzhong Yu

11 May 2023

With recent advancements in artificial intelligence, fundus diseases can be classified automatically for early diagnosis, and this is an interest of many researchers. The study aims to detect the edges of the optic cup and the optic disc of fundus im...

  • Article
  • Open Access
52 Citations
5,820 Views
16 Pages

31 May 2020

In this paper, we propose a method for localizing the optic nerve head and segmenting the optic disc/cup in retinal fundus images. The approach is based on a simple two-stage Mask-RCNN compared to sophisticated methods that represent the state-of-the...

  • Article
  • Open Access
25 Citations
4,618 Views
14 Pages

10 January 2020

Weakly supervised and semi-supervised semantic segmentation has been widely used in the field of computer vision. Since it does not require groundtruth or it only needs a small number of groundtruths for training. Recently, some works use pseudo grou...

  • Article
  • Open Access
5 Citations
2,632 Views
18 Pages

12 November 2022

Currently, glaucoma has become an important cause of blindness. At present, although glaucoma cannot be cured, early treatment can prevent it from getting worse. A reliable way to detect glaucoma is to segment the optic disc and cup and then measure...

  • Article
  • Open Access
1,042 Views
21 Pages

Large Vessel Segmentation and Microvasculature Quantification Based on Dual-Stream Learning in Optic Disc OCTA Images

  • Jingmin Luan,
  • Zehao Wei,
  • Qiyang Li,
  • Jian Liu,
  • Yao Yu,
  • Dongni Yang,
  • Jia Sun,
  • Nan Lu,
  • Xin Zhu and
  • Zhenhe Ma

Quantification of optic disc microvasculature is crucial for diagnosing various ocular diseases. However, accurate quantification of the microvasculature requires the exclusion of large vessels, such as the central artery and vein, when present. To a...

  • Article
  • Open Access
178 Citations
25,190 Views
16 Pages

Dense Fully Convolutional Segmentation of the Optic Disc and Cup in Colour Fundus for Glaucoma Diagnosis

  • Baidaa Al-Bander,
  • Bryan M. Williams,
  • Waleed Al-Nuaimy,
  • Majid A. Al-Taee,
  • Harry Pratt and
  • Yalin Zheng

30 March 2018

Glaucoma is a group of eye diseases which can cause vision loss by damaging the optic nerve. Early glaucoma detection is key to preventing vision loss yet there is a lack of noticeable early symptoms. Colour fundus photography allows the optic disc (...

  • Article
  • Open Access
7 Citations
3,336 Views
14 Pages

Polarformer: Optic Disc and Cup Segmentation Using a Hybrid CNN-Transformer and Polar Transformation

  • Yaowei Feng,
  • Zhendong Li,
  • Dong Yang,
  • Hongkai Hu,
  • Hui Guo and
  • Hao Liu

30 December 2022

The segmentation of optic disc (OD) and optic cup (OC) are used in the automatic diagnosis of glaucoma. However, the spatially ambiguous boundary and semantically uncertain region-of-interest area in pictures may lead to the degradation of the perfor...

  • Proceeding Paper
  • Open Access
1,683 Views
3 Pages

Joint Optic Disc and Cup Segmentation Using Self-Supervised Multimodal Reconstruction Pre-Training

  • Álvaro S. Hervella,
  • Lucía Ramos,
  • José Rouco,
  • Jorge Novo and
  • Marcos Ortega

The analysis of the optic disc and cup in retinal images is important for the early diagnosis of glaucoma. In order to improve the joint segmentation of these relevant retinal structures, we propose a novel approach applying the self-supervised multi...

  • Article
  • Open Access
7 Citations
6,240 Views
25 Pages

17 March 2018

The automatic detection, segmentation, localization, and evaluation of the optic disc, macula, exudates, and hemorrhages are very important for diagnosing retinal diseases. One of the difficulties in detecting such regions of interest (RoIs) with com...

  • Article
  • Open Access
95 Citations
6,995 Views
16 Pages

A Novel Approach for Diabetic Retinopathy Screening Using Asymmetric Deep Learning Features

  • Pradeep Kumar Jena,
  • Bonomali Khuntia,
  • Charulata Palai,
  • Manjushree Nayak,
  • Tapas Kumar Mishra and
  • Sachi Nandan Mohanty

Automatic screening of diabetic retinopathy (DR) is a well-identified area of research in the domain of computer vision. It is challenging due to structural complexity and a marginal contrast difference between the retinal vessels and the background...

  • Article
  • Open Access
11 Citations
4,085 Views
19 Pages

Performance Evaluation of Different Object Detection Models for the Segmentation of Optical Cups and Discs

  • Gendry Alfonso-Francia,
  • Jesus Carlos Pedraza-Ortega,
  • Mariana Badillo-Fernández,
  • Manuel Toledano-Ayala,
  • Marco Antonio Aceves-Fernandez,
  • Juvenal Rodriguez-Resendiz,
  • Seok-Bum Ko and
  • Saul Tovar-Arriaga

2 December 2022

Glaucoma is an eye disease that gradually deteriorates vision. Much research focuses on extracting information from the optic disc and optic cup, the structure used for measuring the cup-to-disc ratio. These structures are commonly segmented with dee...

  • Article
  • Open Access
40 Citations
5,045 Views
17 Pages

Multi-Path Recurrent U-Net Segmentation of Retinal Fundus Image

  • Yun Jiang,
  • Falin Wang,
  • Jing Gao and
  • Simin Cao

29 May 2020

Diabetes can induce diseases including diabetic retinopathy, cataracts, glaucoma, etc. The blindness caused by these diseases is irreversible. Early analysis of retinal fundus images, including optic disc and optic cup detection and retinal blood ves...

  • Article
  • Open Access
1,189 Views
15 Pages

Cup and Disc Segmentation in Smartphone Handheld Ophthalmoscope Images with a Composite Backbone and Double Decoder Architecture

  • Thiago Paiva Freire,
  • Geraldo Braz Júnior,
  • João Dallyson Sousa de Almeida and
  • José Ribamar Durand Rodrigues Junior

11 April 2025

Glaucoma is a visual disease that affects millions of people, and early diagnosis can prevent total blindness. One way to diagnose the disease is through fundus image examination, which analyzes the optic disc and cup structures. However, screening p...

  • Article
  • Open Access
1,448 Views
22 Pages

10 September 2025

Glaucoma is an eye disease caused by increased intraocular pressure (IOP) that affects the optic nerve head (ONH), leading to vision problems and irreversible blindness. Background/Objectives: Glaucoma is the second leading cause of blindness worldwi...

  • Article
  • Open Access
1,448 Views
25 Pages

Analyzing Retinal Vessel Morphology in MS Using Interpretable AI on Deep Learning-Segmented IR-SLO Images

  • Asieh Soltanipour,
  • Roya Arian,
  • Ali Aghababaei,
  • Fereshteh Ashtari,
  • Yukun Zhou,
  • Pearse A. Keane and
  • Raheleh Kafieh

Multiple sclerosis (MS), a chronic disease of the central nervous system, is known to cause structural and vascular changes in the retina. Although optical coherence tomography (OCT) and fundus photography can detect retinal thinning and circulatory...

  • Article
  • Open Access
8 Citations
5,412 Views
15 Pages

Research on the Method of Color Fundus Image Optic Cup Segmentation Based on Deep Learning

  • Zhitao Xiao,
  • Xinxin Zhang,
  • Lei Geng,
  • Fang Zhang,
  • Jun Wu and
  • Yanbei Liu

17 July 2019

The optic cup is a physiological structure in the fundus and is a small central depression in the eye. It has a normal proportion in the optic papilla. If the ratio is large, its size may be used to determine diseases such as glaucoma or congenital m...

  • Article
  • Open Access
5 Citations
3,063 Views
16 Pages

A Method for Retina Segmentation by Means of U-Net Network

  • Antonella Santone,
  • Rosamaria De Vivo,
  • Laura Recchia,
  • Mario Cesarelli and
  • Francesco Mercaldo

5 November 2024

Retinal image segmentation plays a critical role in diagnosing and monitoring ophthalmic diseases such as diabetic retinopathy and age-related macular degeneration. We propose a deep learning-based approach utilizing the U-Net network for the accurat...

  • Article
  • Open Access
4 Citations
3,479 Views
16 Pages

Channel and Spatial Attention Regression Network for Cup-to-Disc Ratio Estimation

  • Shuo Li,
  • Chiru Ge,
  • Xiaodan Sui,
  • Yuanjie Zheng and
  • Weikuan Jia

Cup-to-disc ratio (CDR) is of great importance during assessing structural changes at the optic nerve head (ONH) and diagnosis of glaucoma. While most efforts have been put on acquiring the CDR number through CNN-based segmentation algorithms followe...

  • Article
  • Open Access
8 Citations
3,003 Views
13 Pages

Biomechanical Study of the Osteoporotic Spine Fracture: Optical Approach

  • Mircea Sopon,
  • Valentin Oleksik,
  • Mihai Roman,
  • Nicolae Cofaru,
  • Mihaela Oleksik,
  • Cosmin Mohor,
  • Adrian Boicean and
  • Radu Fleaca

11 September 2021

Background and objectives: Osteoporotic spine fractures represent a significant factor for decreasing quality of life in the elderly female population. Understanding the mechanisms involved in producing these fractures can improve their prevention an...

  • Review
  • Open Access
22 Citations
6,708 Views
21 Pages

A Survey on Diabetic Retinopathy Lesion Detection and Segmentation

  • Anila Sebastian,
  • Omar Elharrouss,
  • Somaya Al-Maadeed and
  • Noor Almaadeed

19 April 2023

Diabetes is a global problem which impacts people of all ages. Diabetic retinopathy (DR) is a main ailment of the eyes resulting from diabetes which can result in loss of eyesight if not detected and treated on time. The current process of detecting...

  • Article
  • Open Access
21 Citations
4,866 Views
17 Pages

EffUnet-SpaGen: An Efficient and Spatial Generative Approach to Glaucoma Detection

  • Venkatesh Krishna Adithya,
  • Bryan M. Williams,
  • Silvester Czanner,
  • Srinivasan Kavitha,
  • David S. Friedman,
  • Colin E. Willoughby,
  • Rengaraj Venkatesh and
  • Gabriela Czanner

Current research in automated disease detection focuses on making algorithms “slimmer” reducing the need for large training datasets and accelerating recalibration for new data while achieving high accuracy. The development of slimmer models has beco...

  • Article
  • Open Access
1 Citations
1,335 Views
18 Pages

Causal Inference-Based Self-Supervised Cross-Domain Fundus Image Segmentation

  • Qiang Li,
  • Qiyi Zhang,
  • Zheqi Zhang,
  • Hengxin Liu and
  • Weizhi Nie

2 May 2025

Accurate glaucoma diagnosis relies on precise segmentation of the optic disc (OD) and optic cup (OC) in retinal images. However, despite the development of numerous automatic segmentation models, the lack of annotations in the target domain and domai...

  • Article
  • Open Access
14 Citations
3,743 Views
20 Pages

Assisting Glaucoma Screening Process Using Feature Excitation and Information Aggregation Techniques in Retinal Fundus Images

  • Ali Raza,
  • Sharjeel Adnan,
  • Muhammad Ishaq,
  • Hyung Seok Kim,
  • Rizwan Ali Naqvi and
  • Seung-Won Lee

4 January 2023

The rapidly increasing trend of retinal diseases needs serious attention, worldwide. Glaucoma is a critical ophthalmic disease that can cause permanent vision impairment. Typically, ophthalmologists diagnose glaucoma using manual assessments which is...

  • Proceeding Paper
  • Open Access
1 Citations
1,968 Views
3 Pages

Fully Automatic Retinal Vascular Tortuosity Assessment Integrating Domain-Related Information

  • Lucía Ramos,
  • Jorge Novo,
  • José Rouco,
  • Stéphanie Romeo,
  • María D. Álvarez and
  • Marcos Ortega

The fundus of the eye is the only part of the human body that allows a direct non-invasive observation of the circulatory system. Retinal vascular tortuosity presents a valuable potential for diagnostic and treatment purposes of relevant vascular and...

  • Review
  • Open Access
42 Citations
8,207 Views
28 Pages

Literature Review on Artificial Intelligence Methods for Glaucoma Screening, Segmentation, and Classification

  • José Camara,
  • Alexandre Neto,
  • Ivan Miguel Pires,
  • María Vanessa Villasana,
  • Eftim Zdravevski and
  • António Cunha

20 January 2022

Artificial intelligence techniques are now being applied in different medical solutions ranging from disease screening to activity recognition and computer-aided diagnosis. The combination of computer science methods and medical knowledge facilitates...

  • Interesting Images
  • Open Access
176 Views
4 Pages

Pigmentary Retinopathy in Alagille Syndrome: Fundus Findings in a Two-Year-Old Boy

  • Bogumiła Wójcik-Niklewska,
  • Zofia Oliwa,
  • Karina Dzięcioł and
  • Adrian Smędowski

Alagille syndrome (ALGS) is a rare autosomal dominant multisystem disorder characterized by bile duct paucity, congenital heart defects, characteristic facial features, skeletal anomalies, and distinctive ocular findings. Although anterior segment an...

  • Article
  • Open Access
7 Citations
3,527 Views
21 Pages

A Teleophthalmology Support System Based on the Visibility of Retinal Elements Using the CNNs

  • Gustavo Calderon-Auza,
  • Cesar Carrillo-Gomez,
  • Mariko Nakano,
  • Karina Toscano-Medina,
  • Hector Perez-Meana,
  • Ana Gonzalez-H. Leon and
  • Hugo Quiroz-Mercado

16 May 2020

This paper proposes a teleophthalmology support system in which we use algorithms of object detection and semantic segmentation, such as faster region-based CNN (FR-CNN) and SegNet, based on several CNN architectures such as: Vgg16, MobileNet, AlexNe...

  • Article
  • Open Access
2 Citations
3,270 Views
15 Pages

4 September 2019

Fundus image segmentation technology has always been an important tool in the medical imaging field. Recent studies have validated that deep learning techniques can effectively segment retinal anatomy and determine pathological structure in retinal f...

  • Article
  • Open Access
2,446 Views
16 Pages

Proliferative Diabetic Retinopathy Diagnosis Using Varying-Scales Filter Banks and Double-Layered Thresholding

  • Noor ul Huda,
  • Anum Abdul Salam,
  • Norah Saleh Alghamdi,
  • Jahan Zeb and
  • Muhammad Usman Akram

Diabetic retinopathy is one of the abnormalities of the retina in which a diabetic patient suffers from severe vision loss due to an affected retina. Proliferative diabetic retinopathy (PDR) is the final and most critical stage of diabetic retinopath...

  • Article
  • Open Access
15 Citations
3,459 Views
24 Pages

24 February 2021

The accurate segmentation of retinal images is a basic step in screening for retinopathy and glaucoma. Most existing retinal image segmentation methods have insufficient feature information extraction. They are susceptible to the impact of the lesion...

  • Article
  • Open Access
47 Citations
7,352 Views
23 Pages

22 July 2019

Retinal blood vessel segmentation influences a lot of blood vessel-related disorders such as diabetic retinopathy, hypertension, cardiovascular and cerebrovascular disorders, etc. It is found that vessel segmentation using a convolutional neural netw...

  • Article
  • Open Access
3 Citations
2,487 Views
15 Pages

Some ocular and cardiovascular diseases can be detected through the increased tortuosity of retinal blood vessels. Objective tortuosity measures can be obtained from digital image analysis of a retinography. This study tested a set of local tortuosit...

  • Article
  • Open Access
7 Citations
3,864 Views
24 Pages

3 September 2024

Glaucoma, a leading cause of permanent blindness worldwide, necessitates early detection to prevent vision loss, a task that is challenging and time-consuming when performed manually. This study proposes an automatic glaucoma detection method on enha...

  • Article
  • Open Access
4 Citations
5,463 Views
17 Pages

Computational Modelling for Efficient Transdentinal Drug Delivery

  • Agathoklis D. Passos,
  • Dimitris Tziafas,
  • Aikaterini A. Mouza and
  • Spiros V. Paras

27 December 2017

This work deals with the numerical investigation of the delivery of potential therapeutic agents through dentinal discs (i.e., a cylindrical segment of the dentinal tissue) towards the dentin–pulp junction. The aim is to assess the main key features...

  • Article
  • Open Access
16 Citations
3,647 Views
17 Pages

Structural Abnormalities of the Optic Nerve and Retina in Huntington’s Disease Pre-Clinical and Clinical Settings

  • Iwona Mazur-Michałek,
  • Katarzyna Kowalska,
  • Daniel Zielonka,
  • Marta Leśniczak-Staszak,
  • Paulina Pietras,
  • Witold Szaflarski,
  • Mark Isalan and
  • Michal Mielcarek

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a polyglutamine expansion in the huntingtin protein. HD-related pathological remodelling has been reported in HD mouse models and HD carriers. In this study, we studied structu...

  • Article
  • Open Access
27 Citations
4,657 Views
18 Pages

Classification of Glaucoma Based on Elephant-Herding Optimization Algorithm and Deep Belief Network

  • Mona A. S. Ali,
  • Kishore Balasubramanian,
  • Gayathri Devi Krishnamoorthy,
  • Suresh Muthusamy,
  • Santhiya Pandiyan,
  • Hitesh Panchal,
  • Suman Mann,
  • Kokilavani Thangaraj,
  • Noha E. El-Attar and
  • Diaa Salama Abd Elminaam
  • + 1 author

This study proposes a novel glaucoma identification system from fundus images through the deep belief network (DBN) optimized by the elephant-herding optimization (EHO) algorithm. Initially, the input image undergoes the preprocessing steps of noise...

  • Article
  • Open Access
1 Citations
1,209 Views
23 Pages

This study presents a U-Net-based automatic segmentation framework for quantitative analysis of surface morphology in a PEEK-based composite following tribological testing. Controlled Pin-on-Disc tests were conducted to characterize tribological perf...

  • Review
  • Open Access
120 Citations
13,773 Views
31 Pages

Retinal Vessels Segmentation Techniques and Algorithms: A Survey

  • Jasem Almotiri,
  • Khaled Elleithy and
  • Abdelrahman Elleithy

23 January 2018

Retinal vessels identification and localization aim to separate the different retinal vasculature structure tissues, either wide or narrow ones, from the fundus image background and other retinal anatomical structures such as optic disc, macula, and...

  • Article
  • Open Access
14 Citations
7,925 Views
23 Pages

Retinal Glaucoma Public Datasets: What Do We Have and What Is Missing?

  • José Camara,
  • Roberto Rezende,
  • Ivan Miguel Pires and
  • António Cunha

2 July 2022

Public databases for glaucoma studies contain color images of the retina, emphasizing the optic papilla. These databases are intended for research and standardized automated methodologies such as those using deep learning techniques. These techniques...

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