The rapid evolution of generative artificial intelligence (AI) is substantially changing archival research methodologies in social sciences. Yet, more structured guidance of methodological protocols informing AI use is needed to mitigate emergent thr...
16 January 2022
This is a protocol for a scoping review that aims to determine how guideline authors using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach have addressed previously identified challenges related to public hea...
This narrative review provides a comprehensive analysis of the several methods and technologies employed to measure handgrip strength (HGS), a significant indicator of neuromuscular strength and overall health. The document evaluates a range of devic...
Applied engineering studies that use evolutionary multi-objective optimisation (MOO) rarely report confidence bounds on the Pareto-optimal solutions they recommend. This paper presents a four-stage sensitivity-analysis protocol that supplies them: cr...
Internet communication is one of the significant aspects of modern civilization. People use banking, health, social, or shopping platforms and send a lot of data. Each communication should be secured and protected against dishonest users’ activ...
Wearable systems are pervading our lives in several applications: from fitness to sport, from health monitoring to rehabilitation, up to prosthetics and empowering human functions through exoskeletons. If the technological requirements are mainly qua...
Among the key computing challenges today are green computing and quantum computing, with the quantum paradigm introducing adverse consequences for many existing cryptographic protocols. However, the entire internet critically depends on these protoco...
22 April 2026
Pressure injuries remain highly prevalent in hospital and home settings, particularly among elderly patients, intensive care unit patients, and individuals with impaired mobility, generating significant healthcare and economic impacts. Although low-l...
Cumulative experiences of racism lead to stress and trauma. Racial trauma is associated with compromised functioning across psychological, social, and physical health domains. This is further complicated by any comorbidity with other mental health co...
Randomized clinical trials are considered the milestones of clinical research in oncology, and guided the development and approval of new compounds so far. In the last few years, however, molecular and genomic profiling led to a change of paradigm in...
Cultural heritage management today faces the challenge of addressing increasingly complex realities. In this context, international organisations focus on identifying heritage attributes that consider not only physical and artistic values, but also s...
8 May 2026
The digital transformation of health systems and the increasing adoption of data-driven public health strategies have intensified the need for methods capable of capturing, structuring, and analyzing information derived from clinical interactions. In...
The performance assessment of routing protocols in vehicular ad hoc networks (VANETs) plays a critical role in testing the efficiency of the routing algorithms before deployment in real conditions. This research introduces the statistical design of e...
Background: Spasticity, affecting over 80% of children with cerebral palsy (CP), is a major source of disability. Transcranial photobiomodulation (tPBM) is a promising non-invasive neuromodulatory intervention, but evidence for its use in pediatric C...
Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS2) guides knowledge production and dissemination in Canada. While it is intended to protect vulnerable populations from harm, it fails to consider Anishinaabe worldviews...
Background: The German S3- guideline on local therapy of leg ulcers and diabetic foot ulcers is in the process of being updated. Major goals are to improve the guidelines’ applicability and to take steps towards a living guideline according to curren...
Recent advances in mobile technology have shown that augmented unisensory feedback can be leveraged to improve gait using wearable systems, but less is known about the possible benefits and usability of multisensory (i.e., multimodal) feedback. This...
21 January 2023
Background: The COVID-19 pandemic has significantly impacted the status of clinical trials in the United States, requiring researchers to reconsider their approach to research studies. In light of this, we discuss the changes we made to the protocol...
A new method to evaluate the energy consumption and driving range of electric vehicles running on intercity routes is proposed. This method consists of a hybridization of a predictive method and the application of online information during the drivin...
In France, around 5% of the general population are taking drug treatments for diabetes mellitus (mainly type 2 diabetes mellitus, T2DM). Although the management of T2DM has become more complex, most of these patients are managed by their general prac...
Background/Objective: Over the past two decades, the utilization of virtual care in rehabilitation has witnessed a significant surge; this is owing to the widespread availability of technological tools and the global impact of the COVID-19 pandemic....
Ex situ machine perfusion has emerged as a pivotal technique for organ preservation and pre-transplant viability assessment, where the real-time monitoring of mitochondrial biomarkers—flavin mononucleotide (FMN) and nicotinamide adenine dinucle...
Teaching of embedded systems, including communication protocols such as SMBus, is commonly faced with difficulties providing the students with interactive and personalized, practical learning experiences. To overcome these shortcomings, this report p...
Background/Objectives: Ancient DNA (aDNA) research workflows heavily depend on efficient aDNA extraction and NGS library preparation. In this study, we compared some of the commonly used laboratory protocols and compared the source of the bone materi...
Large-language models (LLMs) show promise for automating evidence synthesis, yet head-to-head evaluations remain scarce. We benchmarked five state-of-the-art LLMs—openai/o1-mini, x-ai/grok-2-1212, meta-llama/Llama-3.3-70B-Instruct, google/Gemin...
Molecular markers linked to disease resistance genes which affect economically important crops are of great interest. In the case of tomato, a major focus on resistance breeding to multiple fungal and viral pathogens such as Tomato yellow leaf curl v...
The Serial Peripheral Interface (SPI) protocol plays a crucial role in wearable and IoT devices, enabling high-speed communication between microcontrollers and peripherals such as sensors, displays, and connectivity modules. With the increasing compl...
Polystyrene-block-poly (ethylene-ran-butylene)-block-polystyrene (SEBS) was successfully deposited on the copper surface with an optimal condition of immersion protocol. Response surface methodology (RSM), particularly Box–Behnken Design (BBD),...
Background/Objectives: Older adults are particularly susceptible to undernutrition and conditions that can aggravate it, such as frailty and conditions associated with swallowing difficulties or dysphagia. To address these challenges, it is important...
The examination of connected speech may serve as a valuable tool for exploring speech output in both healthy speakers and individuals with language disorders. Numerous studies incorporate various fluency and silence measures into their analyses to in...
There is considerable uncertainty regarding the impact of microembolic signals (MESs) on neuropsychological abilities in patients receiving pulmonary vein isolation and beyond using the cryoballoon technique. We conducted the largest prospective obse...
Background/Objectives: This protocol article presents a methodological framework and does not itself report a new validation dataset. Personalized spine surgery increasingly requires outcome measures that capture recovery domains beyond pain, disabil...
Noncommunicable diseases are the main cause of death globally, and most are potentially preventable; they are long term diseases and generally evolve slowly. In Uruguay 64.9% of the population between 25 and 64 years of age are either overweight or o...
21 December 2022
The social and emotional wellbeing of young Aboriginal and Torres Strait Islander peoples should be supported through an Indigenous-led and community empowering approach. Applying systems thinking via participatory approaches is aligned with Aborigin...
An analytical approach including Panel Test, Isotope Ratio Mass Spectrometry (IRMS) and Nuclear Magnetic Resonance (NMR) spectroscopy was proposed to characterize Italian “Colline Pontine” PDO olive oils (40 samples) of two consecutive cr...
Background: Among all professions, teaching is significantly affected by psycho-social risks with approximately 33.33% of educators reporting work-related fatigue. Suggestopedia, an effective pedagogical approach developed in Bulgaria, claims to indu...
Energy Balance (EB) is an important topic to understand how an imbalance in its main determinants (energy intake and consumption) may lead to inappropriate weight gain, considered to be “dynamic” and not “static”. There are no studies to evaluate EB...
Vehicular networks need to guarantee the communication reliability levels necessary to satisfy the application requirements, while ensuring a stable network operation even under dense deployments. To this aim, congestion and awareness control protoco...
Radio Frequency Identification (RFID) technology faces the problem of message collisions. The coexistence of tags sharing the communication channel degrades bandwidth, and increases the number of bits transmitted. The window methodology, which contro...
Magnetic resonance neurography (MRN), the MR imaging of peripheral nerves, is clinically used for assessing and monitoring peripheral neuropathies based on qualitative, weighted MR imaging. Recently, quantitative MRN has been increasingly reported wi...
The benefits of Pilates have been extensively researched for their impact on muscular, psychological, and cardiac health, as well as body composition, among other aspects. This study aims to investigate the influence of the Pilates method on the lear...
Background: Orthopedic oncology research is hindered by the scarcity of musculoskeletal tumors and research administrative inefficiencies. This paper introduces observational research through an innovative institution-specific methodology—terme...
Background: Placebo has been studied for many years and is ever-present in healthcare. In clinical practice, its use is limited by ethical issues raised by the deception entailed by its administration. Objective: To investigate whether, when given de...
Migrating to Post-Quantum Cryptography (PQC) is critical for securing resource-constrained Internet of Things (IoT) devices against the “harvest-now, decrypt-later” threat. While ML-KEM (CRYSTALS-Kyber) has been standardized under FIPS 20...
The development of quantum computing systems poses a great threat to the security of existing public key-based systems. As a result, the National Institute of Standards and Technology (NIST) started a Post-Quantum Cryptography (PQC) standardization p...
A variety of applications and forwarding protocols have been proposed for opportunistic networks (OppNets) in the literature. However, the methodology of evaluation, testing and comparing these forwarding protocols are not standardized yet, which lea...
The 5G-AKA protocol, a foundational component for 5G network authentication, has been found vulnerable to various security threats, including linkability attacks that compromise user privacy. To address these vulnerabilities, we previously proposed t...
One of the greatest threats to public health in the 21st century is anthropogenic climate change. Healthcare services worldwide account for 4.9% of global CO2 emissions, with operating rooms being the most resource-intensive areas of the hospital. Th...
The Caries Management by Risk Assessment (CAMBRA) protocol consists of analyzing the patient’s profile by assessing the risk and protective factors and assigning a risk level to the patient to allow an individualized treatment plan, which combi...
Pasture-based production systems are predominant in major beef-producing countries; however, these systems lack validated protocols to assess animal welfare under commercial conditions. The objective of this study was to test the feasibility of the p...
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