Metabolomics in Toxicology

Dear Colleagues,

Metabolomics entail the comprehensive analysis of endogenous metabolites in biological systems and seeks to describe how this inventory of small molecules (the metabolome) responds to stress factors such as diseases, drugs or toxicants. By reflecting the complex interplay between gene expression, enzymatic activities and metabolic fluxes, as well as linking genome-encoded events with the environment, the metabolome offers a privileged window onto cellular phenotypes and functional states. Over the last decade, the increasing awareness of the central role of metabolic pathways in biological processes, together with the advances in high-throughput profiling techniques, mainly Nuclear Magnetic Resonance (NMR) spectroscopy and mass spectrometry (MS), have boosted the application of metabolomics in various fields of research, including human health and nutrition, environmental interactions, functional genomics and toxicology.

This Special Issue aims at presenting recent developments and applications of metabolomics in toxicology. The topics to be covered include xenobiotics metabolism and toxicity, preclinical and clinical biomarkers of toxic injury, exposome impact on human health and disease, and ecotoxicology. Manuscripts dealing with other emergent issues in toxicology, such as the impact of nanomaterials on health, and food screening and safety are also highly welcome.

Dr. Iola Duarte
Prof. Ana Gil
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.