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362 Results Found

  • Article
  • Open Access
277 Views
26 Pages

1 December 2025

To address edge contact in non-circular gears arising from installation errors, a modification strategy represented by elliptical gears and driven by an ease-off topological surface is proposed. A tooth surface model for non-circular gears was first...

  • Article
  • Open Access
6 Citations
3,273 Views
14 Pages

Design and Analysis for Hypoid Gears with Ease-Off Flank Modification

  • Qin Wang,
  • Jinke Jiang,
  • Hua Chen,
  • Junwei Tian,
  • Yu Su and
  • Junde Guo

14 January 2022

An approach of ease-off flank modification for hypoid gears was proposed to improve the meshing performance of automobile drive axle. Firstly, a conjugate pinion matching with gear globally was developed based on gear meshing theory. Secondly, a modi...

  • Article
  • Open Access
10 Citations
4,596 Views
11 Pages

Polymeric Coating of Silica Microspheres for Biological Applications: Suppression of Non-Specific Binding and Functionalization with Biomolecules

  • Dario Brambilla,
  • Alessandro Mussida,
  • Anna M. Ferretti,
  • Laura Sola,
  • Francesco Damin and
  • Marcella Chiari

14 February 2022

The use of micro- and nanoparticles in biological applications has dramatically grown during the last few decades due to the ease of protocols development and compatibility with microfluidics devices. Particles can be composed by different materials,...

  • Review
  • Open Access
2 Citations
2,393 Views
23 Pages

Fibroin-Hybrid Systems: Current Advances in Biomedical Applications

  • Matheus Valentin Maia,
  • Eryvaldo Sócrates Tabosa do Egito,
  • Anne Sapin-Minet,
  • Daniel Bragança Viana,
  • Ashok Kakkar and
  • Daniel Crístian Ferreira Soares

15 January 2025

Fibroin, a protein extracted from silk, offers advantageous properties such as non-immunogenicity, biocompatibility, and ease of surface modification, which have been widely utilized for a variety of biomedical applications. However, in vivo studies...

  • Review
  • Open Access
8 Citations
4,527 Views
37 Pages

Recent Advances in Bimetallic Nanoporous Gold Electrodes for Electrochemical Sensing

  • Md. Shafiul Islam,
  • Subrata Banik and
  • Maryanne M. Collinson

8 September 2023

Bimetallic nanocomposites and nanoparticles have received tremendous interest recently because they often exhibit better properties than single-component materials. Improved electron transfer rates and the synergistic interactions between individual...

  • Review
  • Open Access
31 Citations
4,955 Views
21 Pages

Current Progress of Ratiometric Fluorescence Sensors Based on Carbon Dots in Foodborne Contaminant Detection

  • Jialu Zhang,
  • Huinan Chen,
  • Kaidi Xu,
  • Dongmei Deng,
  • Qixian Zhang and
  • Liqiang Luo

7 February 2023

Carbon dots (CDs) are widely used in the detection of foodborne contaminants because of their biocompatibility, photoluminescence stability, and ease of chemical modification. In order to solve the interference problem of complexity in food matrices,...

  • Review
  • Open Access
10 Citations
5,837 Views
16 Pages

15 April 2024

Glycopolymers are functional polymers with saccharide moieties on their side chains and are attractive candidates for biomaterials. Postpolymerization modification can be employed for the synthesis of glycopolymers. Activated esters are useful in var...

  • Review
  • Open Access
1 Citations
2,885 Views
34 Pages

Aptamer Sequence Optimization and Its Application in Food Safety Analysis

  • Xinna Qin,
  • Lina Zhao,
  • Yang Zhang,
  • Jiyong Shi,
  • Haroon Elrasheid Tahir,
  • Xuechao Xu,
  • Kaiyi Zheng and
  • Xiaobo Zou

26 July 2025

Aptamers are single-stranded DNA or RNA oligonucleotides screened by systematic evolution of ligands by exponential enrichment (SELEX) methods, which are widely used in food analysis. Aptamers have the advantages of low molecular weight, ease of prep...

  • Review
  • Open Access
3 Citations
2,823 Views
24 Pages

Gum Rosin in Medical and Pharmaceutical Applications: From Conventional Uses to Modern Advancements

  • Sonita Afrita Purba Siboro,
  • Sabrina Aufar Salma,
  • Syuhada,
  • Kurnia Sari Setio Putri,
  • Frita Yuliati,
  • Won-Ki Lee and
  • Kwon-Taek Lim

13 May 2025

Gum rosin and its derivatives have been used traditionally in coatings and adhesives and are now increasingly applied in diverse medical and pharmaceutical fields. Owing to its film-forming ability, hydrophobic nature, biocompatibility, and ease of c...

  • Review
  • Open Access
69 Citations
11,284 Views
20 Pages

Nucleic acid aptamers are short RNA- or DNA-based affinity reagents typically selected from combinatorial libraries to bind to a specific target such as a protein, a small molecule, whole cells or even animals. Aptamers have utility in the developmen...

  • Review
  • Open Access
25 Citations
5,140 Views
18 Pages

Virus-Incorporated Biomimetic Nanocomposites for Tissue Regeneration

  • Iruthayapandi Selestin Raja,
  • Chuntae Kim,
  • Su-Jin Song,
  • Yong Cheol Shin,
  • Moon Sung Kang,
  • Suong-Hyu Hyon,
  • Jin-Woo Oh and
  • Dong-Wook Han

15 July 2019

Owing to the astonishing properties of non-harmful viruses, tissue regeneration using virus-based biomimetic materials has been an emerging trend recently. The selective peptide expression and enrichment of the desired peptide on the surface, monodis...

  • Review
  • Open Access
54 Citations
8,691 Views
39 Pages

Gold Nanoparticles: Multifaceted Roles in the Management of Autoimmune Disorders

  • Khadijeh Koushki,
  • Sanaz Keshavarz Shahbaz,
  • Mohsen Keshavarz,
  • Evgeny E. Bezsonov,
  • Thozhukat Sathyapalan and
  • Amirhossein Sahebkar

30 August 2021

Gold nanoparticles (GNPs) have been recently applied for various diagnostic and therapeutic purposes. The unique properties of these nanoparticles (NPs), such as relative ease of synthesis in various sizes, shapes and charges, stability, high drug-lo...

  • Proceeding Paper
  • Open Access
1,716 Views
4 Pages

Redox Active Self-Assembled Monolayer Functioning as a pH Actuator

  • Divya Balakrishnan,
  • Wouter Olthuis and
  • César Pascual García

21 November 2018

Using electrochemical control to change the chemical environment in liquids is quite challenging because the small surface to volume ratio offered by traditional cells limits the release or modification of chemicals from the electrodes. Here we prese...

  • Review
  • Open Access
59 Citations
9,031 Views
40 Pages

Recent Progress in Conducting Polymers for Hydrogen Storage and Fuel Cell Applications

  • Neelima Mahato,
  • Hyeji Jang,
  • Archana Dhyani and
  • Sunghun Cho

26 October 2020

Hydrogen is a clean fuel and an abundant renewable energy resource. In recent years, huge scientific attention has been invested to invent suitable materials for its safe storage. Conducting polymers has been extensively investigated as a potential h...

  • Proceeding Paper
  • Open Access
1,926 Views
8 Pages

Impact Assessment of Habitat and Hydromorphological Alterations in Two Heavily Modified Lakes

  • Dionissis Latinopoulos,
  • Chrysoula Ntislidou and
  • Ifigenia Kagalou

A description of hydromorphological pressures is required by the Water Framework Directive, however, there is not a commonly accepted assessment method. This study aims to explore a description tool application, not used before in Greece, for the qua...

  • Review
  • Open Access
31 Citations
6,387 Views
28 Pages

15 July 2021

Environmental pollutants, such as mycotoxins, pesticides, and pharmaceuticals, are a group of contaminates that occur naturally, while others are produced from anthropogenic sources. With increased research on the adverse ecological and human health...

  • Review
  • Open Access
2 Citations
3,102 Views
43 Pages

9 October 2025

SPCEs are crucial for electrochemical sensing because of their portability, low cost, disposability, and ease of mass production. This study details their manufacture, surface modifications, electrochemical characterization, and use in chemical and b...

  • Review
  • Open Access
1,490 Views
31 Pages

Pharmacological and Biological Efficacy of Chitosan-Based Materials

  • Anathi Dambuza,
  • Pennie P. Mokolokolo,
  • Mamookho E. Makhatha and
  • Motshabi A. Sibeko

4 November 2025

Chitosan (CS) is a biodegradable and biocompatible polysaccharide, obtained by the deacetylation of chitin. It has gained significant attention as a versatile material for biomedical applications due to its mucoadhesive properties, ease of chemical m...

  • Review
  • Open Access
2 Citations
2,594 Views
22 Pages

Advances in the Synthesis and Biological Applications of Enoxacin-Based Compounds

  • Garba Suleiman,
  • Nabil El Brahmi,
  • Gérald Guillaumet and
  • Saïd El Kazzouli

7 November 2024

A comprehensive review of advances in the synthesis and biological applications of enoxacin (1, referred to as ENX)-based compounds is presented. ENX, a second-generation fluoroquinolone (FQ), is a prominent 1,8-naphthyridine containing compounds stu...

  • Review
  • Open Access
22 Citations
6,346 Views
27 Pages

Nucleic acid derivatives are imperative biomolecules and are involved in life governing processes. The chemical modification of nucleic acid is a fascinating area for researchers due to the potential activity exhibited as antiviral and antitumor agen...

  • Review
  • Open Access
199 Citations
18,669 Views
25 Pages

Polylactic acid (PLA) filaments are very popular as a thermoplastic source used in the 3D printing field by the “Fused Deposition Modeling” method in the last decade. The PLA market is expected to reach 5.2 billion US dollars in 2020 for...

  • Article
  • Open Access
2,502 Views
13 Pages

THz sources offer the potential for higher frequencies and higher breakdown thresholds in accelerating structures in comparison with conventional RF sources. They also benefit from larger field strengths, field gradients, better beam synchronization...

  • Review
  • Open Access
17 Citations
4,065 Views
17 Pages

5 December 2022

With the rapid development of modern society, environmental problems, including excessive amounts of CO2 released in the atmosphere, are becoming more and more serious. It is necessary to develop new materials and technologies to reduce pollution. Am...

  • Review
  • Open Access
9 Citations
7,380 Views
19 Pages

18 May 2021

Recent advancements in genetic and genome editing research, augmented by the discovery of new molecular tools such as CRISPR, have revolutionised the field of genetic engineering by enabling precise site-specific genome modifications with unprecedent...

  • Review
  • Open Access
1,261 Views
21 Pages

Tailoring Carbon Quantum Dots via Precursor Engineering for Fluorescence-Based Biosensing of E. coli

  • Maryam Nazari,
  • Alireza Zinatizadeh,
  • Parviz Mohammadi,
  • Soheila Kashanian,
  • Mandana Amiri,
  • Nona Valipour,
  • Yvonne Joseph and
  • Parvaneh Rahimi

24 September 2025

Rapid and accurate bacteria identification, particularly Escherichia coli (E. coli), is essential in the monitoring of health, environment, and food safety. E. coli, a prevalent pathogenic bacterium, serves as a key indicator of food and water contam...

  • Article
  • Open Access
8 Citations
5,468 Views
17 Pages

13 April 2020

Geogrid is as one of the component materials classified under the geosynthetics used for soil stabilizing and reinforcement. Due to its higher strength-to-weight ratio, ease of handling, and comparatively low costs, geogrid has been gradually explore...

  • Feature Paper
  • Review
  • Open Access
112 Citations
13,832 Views
20 Pages

Recent Advances in Modified Cellulose for Tissue Culture Applications

  • James C. Courtenay,
  • Ram I. Sharma and
  • Janet L. Scott

Tissue engineering is a rapidly advancing field in regenerative medicine, with much research directed towards the production of new biomaterial scaffolds with tailored properties to generate functional tissue for specific applications. Recently, prin...

  • Review
  • Open Access
9 Citations
2,447 Views
34 Pages

Research Progress on the Surface Modification of Basalt Fibers and Composites: A Review

  • Miaomiao Zhu,
  • Mingming Zhu,
  • Ruoxin Zhai,
  • Wuwei Zhu and
  • Jiabei He

5 March 2025

Fiber-reinforced resin composites (FRRCs) are widely used in several fields such as construction, automotive, aerospace, and power. Basalt fiber (BF) has been increasingly used to replace artificial fibers such as glass fiber and carbon fiber in the...

  • Review
  • Open Access
9 Citations
4,921 Views
22 Pages

Polyelectrolyte Encapsulation and Confinement within Protein Cage-Inspired Nanocompartments

  • Qing Liu,
  • Ahmed Shaukat,
  • Daniella Kyllönen and
  • Mauri A. Kostiainen

24 September 2021

Protein cages are nanocompartments with a well-defined structure and monodisperse size. They are composed of several individual subunits and can be categorized as viral and non-viral protein cages. Native viral cages often exhibit a cationic interior...

  • Article
  • Open Access
3 Citations
3,698 Views
12 Pages

8 February 2021

This research presents an automatic flight control system whose advantage is its ease of modification or maintenance while still effectively meeting the system’s performance requirement. This research proposes a mixed servo state-feedback system for...

  • Article
  • Open Access
5 Citations
1,887 Views
10 Pages

Green-Graphene Protective Overlayer on Optical Microfibers: Prolongs the Device Lifetime

  • Anastasia Novikova,
  • Aviad Katiyi,
  • Aviran Halstuch and
  • Alina Karabchevsky

24 August 2022

Optical microfibers find new applications in various fields of industry, which in turn require wear resistance, environmental friendliness and ease of use. However, optical microfibers are fragile. Here we report a new method to prolong the microfibe...

  • Article
  • Open Access
1 Citations
3,931 Views
16 Pages

28 September 2023

A plasma sheath will be developed surrounding a hypersonic vehicle in flight, which can reflect, absorb, and scatter electromagnetic (EM) waves of lower frequencies than its own, resulting in a communication blackout. This paper focuses on knowing ho...

  • Review
  • Open Access
13 Citations
3,273 Views
20 Pages

Heavy metals in water pose a great threat to human health, and water treatment remains a critical issue globally. Among various water treatment techniques, adsorption has been proven to be an excellent way to remove heavy metals from water due to its...

  • Article
  • Open Access
6 Citations
3,065 Views
11 Pages

A Finite Element Investigation into the Cohesive Properties of Glass-Fiber-Reinforced Polymers with Nanostructured Interphases

  • Mohammad J. Ghasemi Parizi,
  • Hossein Shahverdi,
  • Ehsan Pipelzadeh,
  • Andreu Cabot and
  • Pablo Guardia

24 September 2021

Glass-fiber-reinforced polymer (GFRP) composites represent one of the most exploited composites due to their outstanding mechanical properties, light weight and ease of manufacture. However, one of the main limitations of GFRP composites is their wea...

  • Article
  • Open Access
5 Citations
2,655 Views
13 Pages

22 December 2022

Easy and effective modification approaches for transition metal dichalcogenides are highly desired in order to make them active toward electrocatalysis. In this manner, we report functionalized molybdenum diselenide (MoSe2) and tungsten diselenide (W...

  • Review
  • Open Access
30 Citations
7,044 Views
19 Pages

Aptamer Applications in Emerging Viral Diseases

  • Arne Krüger,
  • Ana Paula de Jesus Santos,
  • Vanessa de Sá,
  • Henning Ulrich and
  • Carsten Wrenger

Aptamers are single-stranded DNA or RNA molecules which are submitted to a process denominated SELEX. SELEX uses reiterative screening of a random oligonucleotide library to identify high-affinity binders to a chosen target, which may be a peptide, p...

  • Review
  • Open Access
58 Citations
8,280 Views
22 Pages

Recent Progress in Modification Strategies of Nanocellulose-Based Aerogels for Oil Absorption Application

  • M. A. Iskandar,
  • Esam Bashir Yahya,
  • H. P. S. Abdul Khalil,
  • A. A. Rahman and
  • M. A. Ismail

22 February 2022

Oil spills and oily wastewater have become a major environmental problem in recent years, directly impacting the environment and biodiversity. Several techniques have been developed to solve this problem, including biological degradation, chemicals,...

  • Review
  • Open Access
14 Citations
928 Views
10 Pages

Recent Advances in Nasoalveolar Molding Therapy Using 3D Technology

  • Sofia Ahsanuddin,
  • Mairaj Ahmed,
  • Leslie Slowikowski and
  • Jenna Heitzler

Presurgical Nasoalveolar Molding (NAM) is an adjunctive treatment modality designed to reorient misaligned tissue structures and nasal cartilage in cleft lip and/or palate (CL/P) patients. Recent advances in NAM therapy focus on modifications to the...

  • Article
  • Open Access
3 Citations
5,450 Views
18 Pages

22 December 2016

The modifier approach has been extensively explored and offers a theoretically-sound and practically-useful method to deploy real-time optimization. The recent directional-modifier adaptation algorithm offers a heuristic to tackle the modifier approa...

  • Review
  • Open Access
105 Citations
8,472 Views
17 Pages

A New Hope: Self-Assembling Peptides with Antimicrobial Activity

  • Lucia Lombardi,
  • Annarita Falanga,
  • Valentina Del Genio and
  • Stefania Galdiero

Peptide drugs hold great promise for the treatment of infectious diseases thanks to their novel mechanisms of action, low toxicity, high specificity, and ease of synthesis and modification. Naturally developing self-assembly in nature has inspired re...

  • Communication
  • Open Access
7 Citations
2,785 Views
8 Pages

pH Measurement at Elevated Temperature with Vessel Gate and Oxygen-Terminated Diamond Solution Gate Field Effect Transistors

  • Shuto Kawaguchi,
  • Reona Nomoto,
  • Hirotaka Sato,
  • Teruaki Takarada,
  • Yu Hao Chang and
  • Hiroshi Kawarada

25 February 2022

Diamond has many appealing properties, including biocompatibility, ease of surface modification, and chemical–physical stability. In this study, the temperature dependence of the pH-sensitivity of a oxygen-terminated boron-doped diamond solutio...

  • Review
  • Open Access
13 Citations
4,838 Views
19 Pages

A Review: Highlighting the Links between Epigenetics, COVID-19 Infection, and Vitamin D

  • Ashmika Foolchand,
  • Siyanda Mazaleni,
  • Terisha Ghazi and
  • Anil A. Chuturgoon

14 October 2022

The highly transmittable and infectious COVID-19 remains a major threat worldwide, with the elderly and comorbid individuals being the most vulnerable. While vaccines are currently available, therapeutic drugs will help ease the viral outbreak and pr...

  • Article
  • Open Access
12 Citations
4,418 Views
13 Pages

11 December 2021

Four different graphene-based nanomaterials (htGO, N-htGO, htGONR, and N-htGONR) were synthesized, characterized, and used as a modifier of carbon paste electrode (CPE) in order to produce a reliable, precise, and highly sensitive non-enzymatic amper...

  • Review
  • Open Access
8 Citations
5,438 Views
57 Pages

An Overview of Innovative Surface-Modification Routes for Pool Boiling Enhancement

  • José Pereira,
  • Reinaldo Souza,
  • António Moreira and
  • Ana Moita

22 February 2024

This overview intends to provide a comprehensive assessment of the novel fluids and the current techniques for surface modification for pool boiling enhancement. The surface modification at macro-, micro-, and nanoscales is assessed concerning the un...

  • Review
  • Open Access
551 Citations
48,278 Views
35 Pages

8 October 2020

A wide range of polymers are commonly used for various applications in prosthodontics. Polymethyl methacrylate (PMMA) is commonly used for prosthetic dental applications, including the fabrication of artificial teeth, denture bases, dentures, obturat...

  • Review
  • Open Access
16 Citations
6,896 Views
27 Pages

Nonreplicating Adenoviral Vectors: Improving Tropism and Delivery of Cancer Gene Therapy

  • Nayara Gusmão Tessarollo,
  • Ana Carolina M. Domingues,
  • Fernanda Antunes,
  • Jean Carlos dos Santos da Luz,
  • Otavio Augusto Rodrigues,
  • Otto Luiz Dutra Cerqueira and
  • Bryan E. Strauss

14 April 2021

Recent preclinical and clinical studies have used viral vectors in gene therapy research, especially nonreplicating adenovirus encoding strategic therapeutic genes for cancer treatment. Adenoviruses were the first DNA viruses to go into therapeutic d...

  • Review
  • Open Access
3 Citations
3,740 Views
12 Pages

Horses for Courses in the Era of CARs: Advancing CAR T and CAR NK Cell Therapies

  • Sergey Kulemzin,
  • Igor Evsyukov,
  • Tatiana Belovezhets,
  • Alexander Taranin and
  • Andrey Gorchakov

11 November 2021

The adoptive transfer of allogeneic CAR NK cells holds great promise as an anticancer modality due to the relative ease of manufacturing and genetic modification of NK cells, which translates into affordable pricing. Compared to the pronounced effica...

  • Review
  • Open Access
31 Citations
7,950 Views
24 Pages

Recent Advances in Aptasensor for Cytokine Detection: A Review

  • Jinmyeong Kim,
  • Seungwoo Noh,
  • Jeong Ah Park,
  • Sang-Chan Park,
  • Seong Jun Park,
  • Jin-Ho Lee,
  • Jae-Hyuk Ahn and
  • Taek Lee

20 December 2021

Cytokines are proteins secreted by immune cells. They promote cell signal transduction and are involved in cell replication, death, and recovery. Cytokines are immune modulators, but their excessive secretion causes uncontrolled inflammation that att...

  • Review
  • Open Access
105 Citations
13,142 Views
21 Pages

25 November 2016

Nucleic acid aptamers generated through an in vitro selection are currently extensively applied as very valuable biomolecular tools thanks to their prominent advantages. Diversity of spatial structures, ease of production through chemical synthesis a...

  • Review
  • Open Access
28 Citations
8,813 Views
20 Pages

Applications of Nanosheets in Frontier Cellular Research

  • Wenjing Huang,
  • Yuta Sunami,
  • Hiroshi Kimura and
  • Sheng Zhang

Several types of nanosheets, such as graphene oxide (GO) nanosheet, molybdenum disulfide (MoS2) and poly(l-lactic acid) (PLLA) nanosheets, have been developed and applied in vitro in cellular research over the past decade. Scientists have used nanosh...

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