Next Article in Journal
Silver Nanoparticles Synthesized Using Wild Mushroom Show Potential Antimicrobial Activities against Food Borne Pathogens
Next Article in Special Issue
Potential of Cellulose Functionalized with Carboxylic Acid as Biosorbent for the Removal of Cationic Dyes in Aqueous Solution
Previous Article in Journal
Identification of the NADPH Oxidase 4 Inhibiting Principle of Lycopus europaeus
Previous Article in Special Issue
Recent Advances in Solvents for the Dissolution, Shaping and Derivatization of Cellulose: Quaternary Ammonium Electrolytes and their Solutions in Water and Molecular Solvents
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessFeature PaperReview
Molecules 2018, 23(3), 654; https://doi.org/10.3390/molecules23030654

Recent Advances in Modified Cellulose for Tissue Culture Applications

1
Centre for Sustainable Chemical Technologies, University of Bath, Bath BA2 7AY, UK
2
Department of Chemistry, University of Bath, Bath BA2 7AY, UK
3
Department of Chemical Engineering, University of Bath, Bath BA2 7AY, UK
*
Author to whom correspondence should be addressed.
Received: 29 January 2018 / Revised: 9 March 2018 / Accepted: 12 March 2018 / Published: 14 March 2018
(This article belongs to the Special Issue Cellulose Chemical Modifications—Towards Sustainable Materials)
Full-Text   |   PDF [3761 KB, uploaded 14 March 2018]   |  

Abstract

Tissue engineering is a rapidly advancing field in regenerative medicine, with much research directed towards the production of new biomaterial scaffolds with tailored properties to generate functional tissue for specific applications. Recently, principles of sustainability, eco-efficiency and green chemistry have begun to guide the development of a new generation of materials, such as cellulose, as an alternative to conventional polymers based on conversion of fossil carbon (e.g., oil) and finding technologies to reduce the use of animal and human derived biomolecules (e.g., foetal bovine serum). Much of this focus on cellulose is due to it possessing the necessary properties for tissue engineering scaffolds, including biocompatibility, and the relative ease with which its characteristics can be tuned through chemical modification to adjust mechanical properties and to introduce various surface modifications. In addition, the sustainability of producing and manufacturing materials from cellulose, as well as its modest cost, makes cellulose an economically viable feedstock. This review focusses specifically on the use of modified cellulose materials for tissue culturing applications. We will investigate recent techniques used to promote scaffold function through physical, biochemical and chemical scaffold modifications, and describe how these have been utilised to reduce reliance on the addition of matrix ligands such as foetal bovine serum. View Full-Text
Keywords: tissue engineering; sustainable chemistry; cellulose; biomaterials; surface modifications; cell culturing; regenerative medicine tissue engineering; sustainable chemistry; cellulose; biomaterials; surface modifications; cell culturing; regenerative medicine
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Courtenay, J.C.; Sharma, R.I.; Scott, J.L. Recent Advances in Modified Cellulose for Tissue Culture Applications. Molecules 2018, 23, 654.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top