The size of chum salmon juveniles is crucial to their survival. In order to understand the population status and migration patterns of juvenile chum salmon in the waters of the Amur River in China, this study investigated the status of juvenile chum...
Anthropogenic structures often block or delay the downstream migration of fish in rivers, thereby affecting their populations. A potential solution at run-of-river hydropower plants (HPPs) is the construction of a fish guidance structure in combinati...
Downstream migration (DSM) of young fish is an efficient dispersal method in rivers. Regulation of rivers transforms them into lotic–limnetic cascades fragmented by dams. Novel conditions of transformed riverine habitats influence the routes an...
Fish need to move upstream and downstream through rivers to complete their life cycles. Despite the fact that fishways are the most commonly applied solution to recover longitudinal connectivity, they are not considered viable for downstream migratio...
The European river lamprey came to the Upper Volga from the Baltic Sea most probably via a system of shipways developed in the 18th and 19th centuries. The Vyshnii Volochek, Tikhvin, and Mariinskaya water systems are possible invasion pathways for th...
Most freshwater fish need to move freely through rivers to complete their life cycles. Thus, river barriers that hinder or block their longitudinal movement (e.g., dams, culverts, gauging stations), directly affect their reproductive, feeding, and ha...
The longitudinal connectivity of many rivers is interrupted by man-made barriers preventing the up- and downstream migration of fishes. For example, dams, weirs, and hydropower plants (HPP) are insuperable obstructions for upstream migration if no sp...
In contrast to the efforts made to develop functioning fishways for upstream migrants, the need for effective downstream migration facilities has long been underestimated. The challenge of developing well-performing bypasses for downstream migrants i...
Bar racks at water intakes of hydropower plants serve mainly to protect the turbines from floating debris. Additionally, they can be utilized to protect downstream migrating fish in order to prevent a potentially harmful turbine passage. The Bar Rack...
Downstream migration (DSM) of fish through the different types of water intakes is not a random process, but rather a selective removal from the limnetic to the lotic parts of river–lake systems. Selectivity means that the assemblage of migrant...
Downstream migration (DSM) of larvae and fry is an important phase of the life cycle of fish as it allows them to disperse, and it increases the size and diversity of the populations via them extending rearing grounds, exchanging genes, and avoiding...
Downstream-migrating fish in rivers tend to follow the main current, and are in danger of swimming through the turbines at run-of-river hydropower plants, possibly causing high mortality rates. To avoid these losses, fish must be prevented from enter...
The current study examined the species composition, timing and cues of the downstream migrations at the confluence of the Zambezi/Chobe River. Daily routine sampling based on inspections and fish measurements of the funnel trap fishery at Impalila Is...
Fish swimming performance is strongly influenced by flow hydrodynamics, but little is known about the relation between fine-scale fish movements and hydrodynamics based on in-situ investigations. In the presented study, we validated the etho-hydrauli...
The fragmentation of rivers caused by the construction of dams and weirs disturbs fish migration and poses a threat to fish populations and aquatic biodiversity. Fish passages around hydraulic structures aim to restore river connectivity; however, th...
Understanding fishway attraction is one of the main open challenges in fishways research, and unraveling the mechanisms and relationships that trigger it is crucial to improve the performance of fishways. Furthermore, attraction is usually understood...
Fish protection at hydropower plants is important for the sustainability of hosting ecosystems and the acceptance of hydropower. On their way downstream, fish are exposed to hydropower plants and various related negative effects, ranging from a delay...
Cancer metastasis accounts for most of the mortality associated with solid tumors. However, antimetastatic drugs are not available on the market. One of the important biological events leading to metastasis is the epithelial to mesenchymal transition...
Background: Schwann cells (SCs) express cholinergic receptors, suggesting a role of cholinergic signaling in the control of SC proliferation, differentiation and/or myelination. Our previous studies largely demonstrated that the pharmacological activ...
Downstream migration of salmonid smolts through regulated rivers remains a major ecological and engineering challenge, with high mortality and delay rates despite mitigation measures like bypasses and guidance systems. This study integrates Computati...
New types of fish guidance structures with vertical curved bars and a subsequent bypass system represent a promising technical solution for the protection and guidance of downstream moving fish at run-of-river hydropower plants and water intakes. The...
Horizontal bar racks have been used as trash racks at hydropower plants since the 1920s. With the installation of the first horizontal bar rack bypass system at a hydropower plant as a downstream fish passage facility in 2006, these racks rapidly gai...
The spatial distribution of fish upstream of a vertical trash rack was investigated at the hydropower plant Kirchbichl in the alpine River Inn (Tyrol, Austria). The objective of the research project “FIDET” was to establish a non-invasive...
This paper investigates the hydraulics and fish guidance efficiency of a Horizontal Bar Rack-Bypass System (HBR-BS) installed at a hydropower plant with a design discharge of 33 m3/s. The HBR is placed at a horizontal rack angle of 38° to the flo...
Horizontal bar racks used as fish protection measures at hydropower plants have rapidly gained importance in recent years. Despite the large number of installed racks in Europe, systematic investigations of the hydraulic losses and velocity fields we...
Fish passage through turbines is one of the main environmental impacts of hydropower. Turbine type is a key factor influencing fish survival, and widespread Kaplan turbines are generally considered less dangerous than other turbine types. Nevertheles...
Retired chemically polluted sites in southern Jiangsu Province, China, are characterized by dense nonaqueous phase liquids (DNAPLs) and extremely thick aquifers (>30 m), which pose substantial challenges for determining investigation and remediati...
Hydrology and temperature are known as key drivers for fish migration in floodplain-channel systems of large rivers. The Lower Irtysh contains valuable species of whitefish and sturgeon. Thus, along the Konda River, a complex study was carried out in...
The Xiaobeiganliu reach is a typical wandering reach of the Middle Yellow River that has rapid and significant channel lateral migration, which may threaten the safety of riparian land and flood control structures. To investigate the characteristics...
Along-slope bottom currents and down-slope (gravity-driven) turbidity currents coexist in the ocean and interact during their flow processes. The interaction between turbidity currents and bottom currents plays a crucial role in determining the later...
The internal architecture of deep-water channels is highly complex. Previous research has primarily emphasized the sedimentary processes governing channel migration, yet the linkage between sediment-source mechanisms and migration patterns—part...
Mitigation measures for downstream-migrating Atlantic salmon smolts (Salmo salar L.) are commonly insufficiently attractive to enable safe entrance and passage with no delay. Combining 2D telemetry with hydrodynamic modelling has been shown to be a g...
Recent reports have indicated prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR). Since this receptor is involved in the promotion of cell proliferation, growth, and migration, we aimed to investigate whether prolidase may pa...
The inertial focusing effect of particles in microchannels shows application potential in engineering practice. In order to study the mechanism of inertial migration of particles with different scales, the motion and distribution of two particles in...
Pleiotrophin (PTN) is a secreted factor that regulates endothelial cell migration through protein tyrosine phosphatase receptor zeta 1 (PTPRZ1) and αvβ3 integrin. Genetic deletion of Ptprz1 results in enhanced endothelial cell proliferatio...
The unique secondary messenger 2′3′-cGAMP, produced by cGAS in response to cytosolic dsDNA, plays a critical role in activating innate immunity by binding to and activating STING via cell-intrinsic, autocrine, or paracrine mechanisms. Rec...
Hydropower infrastructure has profoundly altered riverine connectivity, posing challenges to the migratory behavior of aquatic species. This study examined the post-passage migration efficiency of Schizothorax wangchiachii in a regulated river system...
The role of prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR) was studied in an experimental model of wound healing in cultured fibroblasts. The cells were treated with PEPD (1–100 nM) and analysis of cell viability, p...
Lysine-deficient protein kinase-1 (WNK1) is critical for both embryonic angiogenesis and tumor-induced angiogenesis. However, the downstream effectors of WNK1 during these processes remain ambiguous. In this study, we identified that oxidative stress...
The lateral migration of elastic capsules towards a microchannel centerline plays a major role in industrial and physiological processes. Via our computational investigation, we show that a constriction connecting two straight microchannels facilitat...
Okavango delta is a typical distributive fluvial system, which is composed of a series of sand island-river-swamp networks. River migration in the Okavango delta is analyzed by using satellite images from Google Earth and Alaska Satellite Facility (A...
Glioblastoma (GBM) is the most common primary brain tumor, with poor prognosis and a lack of effective therapeutic options. The aberrant expression of transcription factor REST (repressor element 1-silencing transcription factor) had been reported in...
We conducted experiments using an experimental flume with two variable streambed gradients in the upstream and downstream parts with various debris flows, composition sizes, and supply flow rates. We investigated the transition processes of sediment...
A variety of vascular pathologies, including hypertension, restenosis and atherosclerosis, are characterized by vascular smooth muscle cell (VSMC) hypertrophy and migration. NADPH oxidase 1 (Nox1) plays a pivotal role in these phenotypes via distinct...
Metastatic prostate cancer occurs when the tumor spreads from the prostate gland to other parts of the body. Previous studies have shown that Gαi2, a subunit of the heterotrimeric G protein complex, plays a critical role in inducing cell migrat...
There are seven mammalian isoforms of the 14-3-3 protein, which regulate multiple cellular functions via interactions with phosphorylated partners. Increased expression of 14-3-3 proteins contributes to tumor progression of various malignancies. Seve...
Platelet-derived growth factor-BB (PDGF-BB) and its downstream effector, extracellular signal-regulated kinase 1/2 (ERK1/2) MAP kinase, initiate a multitude of biological effects, including vascular smooth muscle cell (VSMC) proliferation and migrati...
Epidermal growth factor (EGF) receptor activation and related downstream signaling pathways are known to be one of the major mechanisms of the proliferation and migration of keratinocytes. The heparin-binding EGF-like growth factor (HB-EGF) binds to...
∆Np63α is a key transcription factor overexpressed in types of squamous cell carcinomas (SCCs), which represses epithelial–mesenchymal transition (EMT) and cell migration. In this study, we found that CDK1 phosphorylates ∆Np63...
Although the role of platelet-rich plasma (PRP) in tissue regeneration has been confirmed in many studies, the mechanism of this process is still not fully understood. Human keratinocytes (HaCaT) cells were used as an experimental model for studies o...
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