Based on the extended geometric process, a repair replacement model of a degradation system is studied, in which the delayed repair time depends on the working time after the last repair. Replacement and repair thresholds describe when the system wil...
Background/Objectives: The optimal timing for definitive repair of urethral injuries, early versus delayed, remains a subject of ongoing debate. While delayed repair has traditionally been favored to allow resolution of local tissue trauma, emerging...
The concept of a single server retrial queueing system with delayed repair and feedback under a working vacation policy, along with the asymmetric transition representation, is discussed in this article. In addition, consumers are entitled to balk an...
Ophthalmic units use sophisticated equipment to enable accurate diagnosis of refractive errors. This equipment is subject to two types of breakdowns. One is simple breakdown which can be repaired in-house, and the other is complex breakdown which req...
Rotator cuff tears are a frequent cause of shoulder pain that often require arthroscopic repair. After surgery an intense and well-studied rehabilitation protocol is needed to obtain the complete recovery of shoulder function. Fifty patients, who sus...
Background: Our purpose was to evaluate whether the time of intervention and the type of meniscus surgery (repair vs. partial meniscectomy) play a role in managing anterior cruciate ligament (ACL) reconstructions with concurrent meniscus pathologies....
Glucocorticoids delay fracture healing and induce osteoporosis. However, the mechanisms by which glucocorticoids delay bone repair have yet to be clarified. Plasminogen activator inhibitor-1 (PAI-1) is the principal inhibitor of plasminogen activator...
We investigated injury-induced heat shock protein 27 (HSP27) expression and its association to axonal outgrowth after injury and different nerve repair models in healthy Wistar and diabetic Goto-Kakizaki rats. By immunohistochemistry, expression of H...
With the development and popularization of cloud storage technology, cloud storage has become a main method of data storage. Aiming at the problem of large delay and low availability incurred by multiple invalid nodes in cloud storage, a new type of...
Dysfunctions in the intestinal barrier, associated with an altered paracellular pathway, are commonly observed in inflammatory bowel disease (IBD). The AMP-activated protein kinase (AMPK), principally known as a cellular energy sensor, has also been...
Background/Objectives: Avulsion is a major cause of tooth loss, and its treatment involves replantation. This study analyzed the repair process of incisive teeth subjected to delayed replantation after topical treatment with ampicillin and tetracycli...
The bondline integrity of a repair patch to the parent composite laminate is considered the most important factor in the repair design. A smart repair patch is proposed here to allow for real-time ultrasonic guided wave monitoring of repaired composi...
Background/Objective: Traumatic injuries to the flexor tendons of the hand are frequently treated by hand surgeons. Late repair is not classically considered to be feasible due to the high risk of failure and functional complications. The present stu...
In this study, a single-pulse laser technique was applied to repair the cracked plate. The idea of this technique is based on delaying fatigue crack propagation by irradiating the area ahead of the crack tip by using a single-pulse laser with a high...
Background. Delayed graft function is a frequent complication of kidney transplantation that requires dialysis in the first week posttransplant. Materials and Methods. We searched for the most relevant articles in the National Institutes of Health li...
Heat stress due to climate warming can significantly affect the synthesis of sex hormones in male adolescents, which can impair the ability of the hypothalamus to secrete gonadotropin-releasing hormone on the hypothalamic–pituitary–gonada...
Injuries to peripheral nerves are frequent in serious traumas and spinal cord injuries. In addition to surgical approaches, other interventions, such as cell transplantation, should be considered to keep the muscles in good condition until the axons...
This study analyzes three availability systems with warm standby units, fault detection delay, and general repair times. The failure times and repair times of failed components were assumed to follow exponential and general distributions, respectivel...
In some settings, systems may not fail completely but instead undergo performance degradation, leading to reduced efficiency. A significant concern arises when a system transitions into a degraded state without immediate detection, with the degradati...
Injured peripheral nerves regenerate their axons in contrast to those in the central nervous system. Yet, functional recovery after surgical repair is often disappointing. The basis for poor recovery is progressive deterioration with time and distanc...
Cyclobutane pyrimidine dimers (CPDs) are ultraviolet radiation (UV)-induced carcinogenic DNA photoproducts that lead to UV signature mutations in melanoma. Previously, we discovered that, in addition to their incident formation (iCPDs), UV exposure i...
Background: Pediatric hard-to-heal wounds are rare but clinically demanding due to skin immaturity, comorbidities, and infection risk. Methods: This prospective case series evaluated the feasibility, safety, and clinical outcomes of an injectable hya...
Background: The principle of early flap reconstruction for high-grade traumatic lower-extremity injuries established in 1986 by Godina has been widely accepted. However, the lack of an orthoplastic center in China makes early reconstruction not acces...
DNA damage is induced by both endogenous and exogenous factors. Repair of DNA double-strand break (DSB), a serious damage that threatens genome stability, decreases with senescence. However, the molecular mechanisms underlying the decline in DNA repa...
Spermatids are extremely sensitive to genotoxic exposures since during spermiogenesis only error-prone non homologous end joining (NHEJ) repair pathways are available. Hence, genomic damage may accumulate in sperm and be transmitted to the zygote. In...
The concept of seismic resilience has been introduced in the design of buildings in the last decade. In this regard, the delay time may be defined as the time that occurs between the event and the moment the repair process begins. In the literature,...
Inguinal hernia repair (IHR) is a common surgical procedure among neonates and infants; the time of surgery is one of the major factors affecting its outcomes. Our systematic review aims to evaluate the effects of surgical timing on outcomes in ingui...
Iatrogenic bile duct injury (IBDI) constitutes a major complication of cholecystectomy. The optimal timing, method, and setting for definitive repair remain subjects of debate. This study aimed to systematically evaluate management strategies, timing...
11 October 2022
Background: A delay in muscle repair interferes with the effect of training or exercise; therefore, it is important to identify the factors that delay muscle repair. P. gingivalis, one of the most common periodontal disease pathogens, has the potenti...
Efficient repair of skeletal muscle relies upon the precise coordination of cells between the satellite cell niche and innate immune cells that are recruited to the site of injury. The expression of pro-inflammatory cytokines and chemokines such as T...
Targeting DNA repair pathways is an important strategy in anticancer therapy. However, the unrevealed interactions between different DNA repair systems may interfere with the desired therapeutic effect. Among DNA repair systems, BER and NHEJ protect...
Inappropriate repair of DNA double-strand breaks (DSBs) leads to genomic instability, cell death, or malignant transformation. Cells minimize these detrimental effects by selectively activating suitable DSB repair pathways in accordance with their un...
Background: Parotidectomies are indicated for a variety of reasons. Regardless of the indication for surgery, facial reanimation may be required because of facial nerve sacrifice or iatrogenic damage. In these cases, facial restoration performed conc...
Traumatic abdominal wall hernias (TAWH) occur in less than one percent of trauma presentations. In the absence of clinical guidelines, management is centre-specific and largely dependent on surgeon experience. This study describes the management of T...
Removing excess material from build-up welding by milling is a critical step in the repair of blades from aircraft engines. This so-called recontouring is a very challenging machining task. Shape deviations often result from the deflection of tool an...
Early diagnosis and therapy in axial spondyloarthritis, axSpA, is known to reduce long-term morbidity. However, the time from symptom onset to diagnosis is typically delayed by several years, and this situation has not improved in recent years despit...
UV-induced DNA damage response and repair are extensively studied processes, as any malfunction in these pathways contributes to the activation of tumorigenesis. Although several proteins involved in these cellular mechanisms have been described, the...
24 July 2015
Reconstruction of posttraumatic orbital defects carries the attendant risk of injury to the ocular adnexa, globe, and associated neurovascular structures. Blindness following repair of orbital fractures is an infrequent but well-documented phenomenon...
Alkali–silica reaction (ASR) can create significant cracking, compromising the durability and structural integrity of concrete elements. Currently, there is no known way to halt or reverse ASR damage, and the expansion will continue until it im...
With advanced digital technologies as the key support, many scholars and researchers have proposed various random warranty models by integrating mission cycles into the warranty stage. However, these existing warranty models are designed only from th...
During Bacillus subtilis spore germination/outgrowth, the rehydration of the spore core and activation of aerobic metabolism can generate reactive oxygen species (ROS)-promoted DNA lesions that are repaired via the base excision repair pathway (BER)....
Size-controlled spherical silver nanoparticles (<10 nm) and chitin-nanofiber sheet composites (Ag NPs/CNFS) have previously been reported to have strong antimicrobial activity in vitro. Although Ag NPs/CNFS have strong antimicrobial activity, thei...
Self-healing cement composites are generally produced by using materials such as inorganic powders, bacteria pellets, and microcapsules. Among them, inorganic powder-type healing materials tend to decrease in healing performance over time because the...
In the distributed storage system, when data need to be recovered after node failure, the erasure code redundancy method occupies less storage space than the multi-copy method. At present, the repair mechanism using erasure code to reconstruct the fa...
Rapid advancement of data management and sharing technology has urged organizations to develop effective maintenance management systems. This research, therefore, proposes and implements an Electronic Repair Records (ERR) system for the blockchain of...
Articular cartilage is crucial for joint function but its avascularity limits intrinsic repair, leading to conditions like osteoarthritis (OA). Chondromodulin-I (Cnmd) has emerged as a key molecule in cartilage biology, with potential implications fo...
Blunt thoracic aortic injury (BTAI) is a potentially fatal condition that needs prompt recognition and expedited management. Clinical manifestations of BTAI are not straight forwarding and may be misdiagnosed. The grade of aortic injury is an importa...
Radiation is unavoidable in space. Energetic particles in space radiation are reported to induce cluster DNA damage that is difficult to repair. In this study, normal human fibroblasts were irradiated with components of space radiation such as proton...
Potholes are typical scattered distresses on asphalt pavements, severely impairing traffic safety and pedestrian safety due to delayed repair time and secondary distress. Aiming to extend the service life of repaired potholes, this study develops a p...
The bond interface is the weakest part of the repair system, and its performance is a key factor impacting the repair effectiveness of damaged concrete constructions. However, the research on the damage law and the mechanism of repair of the bonded i...
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