649 Results Found

Remote-sensing images of high spatial resolution (HSR) are valuable sources of fine-grained spatial information for various applications, such as urban surveys and governance. There is continuing research on positional errors in remote-sensing images...

Carbon dots (CDs) are engineered nanoparticles that are used in a number of bioapplications such as bioimaging, drug delivery and theranostics. The effects of CDs on the immune system have not been evaluated. The effects of CDs on the immune system w...

Dysphagia is prevalent in patients with cervical dystonia (CD) and is a potential adverse event in patients treated with botulinum neurotoxin (BoNT) for CD. Real-world studies may provide a better understanding of the incidence and potential risk fac...

Costimulatory molecules facilitate cross-talks among leukocytes via mutual stimulatory and inhibitory signalling, contributing to diverse immunological outcomes in normal physiological responses and pathological conditions. Systemic lupus erythematos...

Immune checkpoint inhibitors (ICIs) targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), programmed cell death protein (PD-1), and its ligand PDL-1, are finding increasing application in the treatment of malignant neoplasms. The widespread...

Background/Objectives: Common Variable Immunodeficiency Disease (CVID) and other immunodeficiencies can present in subtle and variable ways. Whether or not a genetic lesion can be identified, there are not well understood biomarkers that quantitative...

Cadmium (Cd) is a toxic heavy metal with very low permissible exposure limits and is, thus, a very dangerous pollutant for the environment and public health and is considered by the World Health Organisation as one of the ten chemicals of major publi...

CD5 and CD6 are closely related signal-transducing class I scavenger receptors mainly expressed on lymphocytes. Both receptors are involved in the modulation of the activation and differentiation cell processes triggered by clonotypic antigen-specifi...

CD8+ T cells protect against tumors and intracellular pathogens. The inflammatory cytokines IL-2, IL-15, and IL-7 are necessary for their expansion. However, elevated serum levels of these cytokines are often associated with cancer, poorer prognosis...

A mixture of the environmentally friendly biosurfactants rhamnolipids and sophorolipids was used as a source of micelles in this study. The Box-Behnken design and response surface methodology was used to investigate the influence of factors on micell...

In order to effectively decrease cadmium (Cd) in rice grains in contaminated paddy soil and maintain the safe production of rice, identifying excessive Cd in rice caused by rice varieties or soil Cd is critical, but it is currently lacking. In the pr...

Microscopic colitis (MC) and coeliac disease (CD) are common associated gastrointestinal conditions. We present the largest study assessing hospitalisation in patients with MC and the effect of a concomitant diagnosis of CD. Data were retrospectively...

Variance-component models are an indispensable tool for statisticians wanting to capture both random and fixed model effects. They have applications in a wide range of scientific disciplines. While maximum likelihood estimation (MLE) is the most popu...

Change detection (CD) based on remote sensing images plays an important role in Earth observation. However, the CD accuracy is usually affected by sunlight and atmospheric conditions and sensor calibration. In this study, a scale-driven CD method inc...

Background: Cinnarizine (CIN) is a poorly soluble drug used in the treatment of vestibular disorders. Its solubility can be improved by complexation with cyclodextrins (CDs). This study focused on the preparation of 1:1 CIN/CD complexes with β-c...

The aim of this study was to establish a cell culture system for the generation of porcine monocyte-derived macrophages (MDMs) under reduced-serum conditions. Cultures based on either the Nu-Serum™ Growth Medium Supplement (NUS) or a convention...

Industrial collaborative robots (cobots) are known for their ability to operate in dynamic environments to perform many different tasks (since they can be easily reprogrammed). Due to their features, they are largely used in flexible manufacturing pr...

A two-year field study was performed to evaluate the cadmium (Cd) phytoremediation potential of two hyperaccumulators, Sedum alfredii (S.A.) and Sedum plumbizincicola (S.P.), in contaminated farmland. Biomass and Cd uptake in both species followed lo...

The aim of this work was to evaluate the possibility of applying the dried biomass of E. gracilis var. bacillaris as a biosorbent for the removal of Cd. Experiments were carried out under conditions of batch systems involving aqueous solutions labell...

Celiac disease (CD) is frequently associated with other autoimmune disorders. Different studies have explored the association between CD and single autoimmune endocrine disease (AED), especially autoimmune thyroiditis (AIT) and type-1 diabetes mellit...

Radial gates are widely used for agricultural water management, flood controlling, etc. The existence of methods for the calculation of the discharge coefficient (Cd) of such gates are complex and they are based on some assumptions. The development o...

(1) Background: SARS-CoV-2 infection during pregnancy could determine important maternal and fetal complications. We aimed to prospectively assess placental immunohistochemical changes, immunophenotyping alterations, and pregnancy outcomes in a cohor...

The membrane glycoprotein CD133 (prominin-1) is widely regarded as the main molecular marker of cancer stem cells, which are the most malignant cell subpopulation within the tumor, responsible for tumor growth and metastasis. For this reason, CD133 i...

Carbonaceous and calcareous materials are commonly used as amendments to decrease the Cd mobility in contaminated soils. This study evaluated the effect of amendments applied to cocoa seedlings in the greenhouse, considering the mobilization of soil...

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to...

Several harmful modifications in different tissues-organs, leading to relevant diseases (e.g., liver and lung diseases, neurodegeneration) are reported after exposure to cadmium (Cd), a wide environmental contaminant. This arises the question whether...

Celiac disease (CD) is an autoimmune disorder caused by gluten intake in genetically predisposed individuals. This article provides an overview of the available data on the risks of infectious diseases and the mechanisms involved in CD, including a d...

In the change detection (CD) task, the substantial variation in feature distributions across different CD datasets significantly limits the reusability of supervised CD models. To alleviate this problem, we propose an illumination–reflection de...

Type 1 diabetes is caused by autoreactive T cells that destroy pancreatic beta cells. Animal models suggested that a CD4+CD25+ population has a regulatory function capable of preventing activation and effector functions of autoreactive T cells. Howev...

Ca2+ channel blockers (CCBs) are commonly used to treat different cardiovascular conditions. These drugs disrupt the intracellular Ca2+ signaling network, inhibiting numerous cellular functions in different cells, including T lymphocytes. We explored...

Cellular responses to micro- and hypergravity are rapid and complex and appear within the first few seconds of exposure. Transcriptomic analyses are a valuable tool to analyze these genome-wide cellular alterations. For a better understanding of the...

Cadmium (Cd) is a heavy metal present in atmosphere, rocks, sediments, and soils without a known role in plants. It is relatively mobile and can easily enter from soil into groundwater and contaminate the food chain. Its presence in food in excess am...

The purpose of the paper is to investigate the relationship between sovereign Credit Default Swap (CDS) and stock markets in nine emerging economies from Central and Eastern Europe (CEE), using daily data over the period January 2008–April 2018...

The classic solar cell model assumes that the photo-generated current is a constant, independent of the cell’s output voltage. Experimental data of CdTe solar cells, however, show that the photocurrent collection efficiency decreases with the increas...

Cadmium (Cd) and drought stresses are becoming dominant in a changing climate. This study explored the impact of Cd and Cd + drought stress on durum wheat grown in soil and sand at two Cd levels. The physiological parameters were studied using classi...

Cadmium (Cd) is a naturally occurring element often associated with lead (Pb) in the Earth’s crust, particularly in karst regions, posing significant safety hazards for locally grown rice. Identifying the key factors controlling Cd and Pb conte...

In non-small cell lung cancer (NSCLC), stroma-resident and tumour-infiltrating macrophages may facilitate an immunosuppressive tumour microenvironment (TME) and hamper immunotherapeutic responses. Analysis of tumour-associated macrophage (TAM) plasti...

Changes in the macrophage infiltration of kidneys in rodents under ischemic conditions may affect cardiac macrophages and lead to development of adaptive cardiac remodeling. The aim of our study was to translate experimental findings into clinically...

CAR-T cell therapy is not without some clinical adverse effects, namely cytokine storms, due to a massive release of cytokines when CAR-T cells multiply in the body. Our goal was to develop exosomes expressing CD19 CAR to treat CD19-positive B-cell m...

For patients with acute myeloid leukemia, myelodysplastic syndrome, or acute lymphoblastic leukemia, allogeneic hematopoietic cell transplantation (HCT) is a potentially curative treatment. In addition to standard conditioning regimens for HCT, high-...

Tetraspanins are a conserved family of proteins involved in a number of biological processes including, cell–cell interactions, fertility, cancer metastasis and immune responses. It has previously been shown that TSPAN32 knockout mice have norm...

Xeroderma Pigmentosum (XP) is a DNA repair disease characterized by nucleotide excision repair (NER) malfunction, leading to photosensitivity and increased incidence of skin malignancies. The role of XP-A in NER pathways has been well studied while d...

This study reports the adsorption capacity of lead Pb2+ and cadmium Cd2+ of biochar obtained from: peanut shell (BCM), “chonta” pulp (BCH) and corn cob (BZM) calcined at 500, 600 and 700 °C, respectively. The optimal adsorbent dose, p...

Epidemiology of hepatocellular carcinoma (HCC) showed a correlation between incidence and geographical-relevant risk factors. This study aims to compare the distributions of cancer stem cells (CSC) in two distant populations in Asia and Europe. We an...

Atypical antipsychotics currently constitute the first-line medication for schizophrenia, with quetiapine being one of the most commonly prescribed representatives of the group. Along with its specific affinity for multiple receptors, this compound e...

Aneurysmal subarachnoid hemorrhage (aSAH) is a serious condition complicated by delayed cerebral ischemia (DCI), where inflammation plays a key role. Although altered gut permeability is noted in other conditions, its significance in aSAH remains unc...

Endothelial-like cells may be obtained from CD133+ mononuclear cells isolated from human umbilical cord blood (hUCB) and expanded using endothelial-inducing medium (E-CD133 cells). Their use in regenerative medicine has been explored by the potential...

Cushing’s disease (CD) is a rare condition caused by adrenocorticotropic hormone (ACTH)-producing adenomas of the pituitary, which lead to hypercortisolism that is associated with high morbidity and mortality. Treatment options in case of persi...

Spermatozoa (SPZ) are sensitive to stressful conditions, particularly oxidative stress, which alters their quality; thus, the use of protective molecules as an antioxidant is encouraged. Herein, we used melatonin (MLT) to investigate its in vitro eff...

Several immunotherapeutic strategies for the treatment of cancer are under development. Two prominent strategies are adoptive cell transfer (ACT) of CTLs and modulation of CTL function with immune checkpoint inhibitors or with costimulatory antibodie...