117 Results Found

Twelve new bis-Schiff bases of isatin, benzylisatin and 5-fluoroisatin 3a-3l were prepared by condensation of isatin, benzylisatin and 5-fluoroisatin with primary aromatic amines. The chemical structures of the products were confirmed by ¹H- and ¹³CN...

This study was carried out to synthesize benzotriazole-based bis-Schiff base scaffolds (1–20) and assess them in vitro for α-glucosidase inhibitory potentials. All the synthetics analogs based on benzotriazole-based bis-Schiff base scaffo...

Condensation of aromatic primary bis-amines with isatin (1H-indole-2,3-dione) and 5-flouroisatin occurred cleanly and efficiently in a water suspension mediumwithout using any organic solvent or acid catalyst. The corresponding bis-Schiff baseswere o...

Corrosion inhibitors are widely used as an important tool for the prevention and remediation of different materials exposed to corrosive industrial processes. Corrosion inhibitors are usually added to acid pickling solutions to reduce the deteriorati...

Isatin (1H-indole-2,3-dione) was first obtained by Erdman and Laurent in 1841 as a product from the oxidation of indigo by nitric and chromic acids [1].[...]

A new bis-Schiff base (L) Ca(II) complex, CaL, was synthesized by the reaction of calcium perchlorate tetrahydrate, 1,3-diamino-2-hydroxypropane, and 2-formyl phenoxyacetic acid in an ethanol–water (v:v = 2:1) solution and characterized by IR,...

The current work involves the synthesis of 2,2′-(6-(piperidin-1-yl)-1,3,5-triazine-2,4-diyl)bis(hydrazin-2-yl-1-ylidene))bis(methanylylidene))diphenol 4, characterization, and the DFT studies of the reported compound. The crystal unit cell parameters...

A series of new 1,2/1,3-bis[o-(N-methylidenamino-3-aryl-5-phenyl-4H-1,2,4-triazole-4-yl)phenoxy]ethane/propane derivatives 4 were prepared in good yields bytreatment of 4-amino-3-aryl-5-phenyl-4H-1,2,4-triazoles 2 with certain bis-aldehydes 1.Compoun...

A new electrochemical sensor of metal cation in an aqueous solution based on homobifunctional tridentate disulfide Schiff base and named 1,1′-(-((disulfanediylbis(2,1-phenylene))bis(azaneylylidene))bis(methaneylylidene))bis(naphthalene-2-ol) (A...

Schiff bases, named after Hugo Schiff, are highly reactive organic compounds broadly used as pigments and dyes, catalysts, intermediates in organic synthesis, and polymer stabilizers. Lots of Schiff bases are described in the literature for various b...

A novel Schiff base ligand derived from 2,2'-bis(p-methoxyphenylamine) and salicylicaldehyde and its transition metal complexes with Cu (Ⅱ), Co (Ⅱ) and Mn (Ⅱ) have been synthesized. Their spectral properties and electrochemical behavior were investig...

Five 6,6′-dimethyl-2,2′-bipyridine ligands bearing N-arylmethaniminyl substituents in the 4- and 4′-positions were prepared by Schiff base condensation in which the aryl group is Ph (1), 4-tolyl (2), 4-^tBuC₆H₄ (3), 4-MeOC₆H₄ (4), an...

In this study, a new bi-nuclear nickel complex [Ni₂HL₂(EtOH)₂](Cl)(EtOH) of a Schiff base ligand, 2-[3-[2-hydroxybenzylideneamino]propyliminomethyl]phenol, was synthesized and characterized using UV/Vis, IR, HRMS, and TGA/DTA analysis. The molecular...

Bis-aldehyde monomers 4-(4′-formyl-phenoxy)benzaldehyde (3a), 3-methoxy-4-(4′-formyl-phenoxy)benzaldehyde (3b), and 3-ethoxy-4-(4′-formyl-phenoxy)benzaldehyde (3c) were synthesized by etherification of 4-fluorobenzaldehyde (1) with...

A series of symmetrical salicylaldehyde-bishydrazine azo molecules, 5a–5h, have been synthesized, characterized by ¹H-NMR and ¹³C-NMR, and evaluated for their in vitro α-glucosidase and α-amylase inhibitory activities. All the synth...

Manganosalen complexes are coordination compounds that possess a chelating salen-type ligand, a class of bis-Schiff bases obtained by condensation of salicylaldehyde and a diamine. They may act as catalytic antioxidants mimicking both the structure a...

A series of colorful binuclear Schiff bases derived from the different diamine bridges including 1,2- ethylenediamine (bis-Et-SA, bis-Et-4-NEt₂, bis-Et-5-NO₂, bis-Et-Naph), 1,2-phenylenediamine (bis-Ph-SA, bis-Ph-4-NEt₂, bis-Ph-5-NO₂, bis-Ph-Naph), d...

A series of pyridine-bridged 2,6-bis-carboxamide Schiff's bases has been prepared starting from 2,6-pyridinedicarbonyl dichloride (1) and L-alanine or 2-methyl-alanine methyl ester.The coupling of acid chloride 1 with L-alanine methyl ester hydrochlo...

1,3-Bis[(E)-(3-bromobenzylidene)amino]propan-2-ol Schiff base was synthesized in an acceptable yield by condensation of 3-bromobenzaldehyde with 1,3-diaminopropan-2-ol in methanol. The structure of the desired Schiff base compound was spectroscopical...

Marine alkaloids belonging to the lamellarins family, which incorporate a 5,6-dihydro-1-phenylpyrrolo[2,1-a]isoquinoline (DHPPIQ) moiety, possess various biological activities, spanning from antiviral and antibiotic activities to cytotoxicity against...

A series of Bis-pyrazole Schiff bases (6a–d and 7a–d) and mono-pyrazole Schiff bases (8a–d and 9a–d) were designed and synthesized through the reaction of 5-aminopyrazoles 1a–d with aldehydes 2–5 using mild reactio...

Leishmaniasis, caused by the protozoan Leishmania spp. and transmitted by sandflies, affects 2 million people worldwide yearly and is recognized as a global problem by the WHO. Current treatments, including amphotericin B, Pentamidine, and Glucantime...

In an effort to develop new antibacterial drugs, some novel bisindolylmethane derivatives containing Schiff base moieties were prepared and screened for their antibacterial activity. The synthesis of the bisindolylmethane Schiff base derivatives 3–26...

Four flavanone Schiff bases (E)-1-(2-phenylchroman-4-ylidene)thiosemicarbazide (FTSC) (1), N′,2-bis((E)-2-phenylchroman-4-ylidene)hydrazine-1-carbothiohydrazide (FTCH) (2), (E)-N’-(2-phenylchroman-4-ylidene)benzohydrazide (FHSB) (3) and (E)-N′-(2-phe...

Several fused imidazolopyrimidines were synthesized starting from 6-amino-1-methyl-2-thiouracil (1) followed by nitrosation, reduction and condensation with different aromatic aldehydes to give Schiff’s base. The dehydrocyclization of Schiff’s bases...

The widespread usage of Schiff bases in chemistry, industry, medicine, and pharmacy has increased interest in these compounds. Schiff bases and derivative compounds have important bioactive properties. Heterocyclic compounds containing phenol derivat...

This paper reports the syntheses, crystal structures and magnetic properties of Mn(III) hexadentate Schiff base complexes [Mn(4-OH-sal-N-1,5,8,12)]NO₃(1) and [Mn(4-OH-sal-N-1,5,8,12)]ClO₄(2), where (4-OH-sal-N-1,5,8,12)²⁻ (4,4′-((1E,13E)-...

Amino acid Schiff base Cu(II) complexes were synthesized under microwave irradiation using methanol as a solvent, to maximize the best conditions to obtain the attained compounds, containing aromatics possessing no, one or two chlorine atoms. The com...

The zinc(II) ion forms stable complexes with a wide variety of ligands, but those related to Schiff-bases are among the most largely investigated. This review deals with the peculiar aggregation characteristics of Zn(II) Schiff-base complexes from te...

New crown ether Schiff base derivatives were prepared by the condensation of4’-formylbenzo-15-crown-5 or 4’-formyl-5’-hydroxybenzo-15-crown-5 with 1,2-bis(2-aminophenoxy)ethane. The structures of these new compounds were confirmed on thebasis of elem...

Whereas there is an increasing amount of reports on the second-order nonlinear optical (NLO) and luminescence properties of tetradentate [N₂O₂] Schiff base–zinc complexes, the study of zinc complexes having two bidentate [NO] Schiff-base ligand...

A new cobalt(III) complex with a pentadentate Schiff base was synthesized using a reaction of 2,2′-{(2-hydroxypropane-1,3-diyl)bis(nitriloeth-1-yl-1-ylidene)}diphenol (H₃L) and cobalt(II) acetate in a methanolic solution. This synthesis resulte...

Schiff-Base complexes of bis-5-phenylazosalicylaldehyde ethylenediimine and bis-5-phenylazosalicylaldehyde-O-phenylenediimine ligands with Co(II) (I and II) have been synthesized and characterized by their IR spectra and elemental analyses. These com...

Due to the obvious numerous economic and technical consequences of the corrosion process, its inhibition is one of the most critical aspects of current research. A corrosion inhibitor for the bis-thiophene Schiff base copper–metal complex Cu(II...

Schiff bases constitute a broad and well-established class of ligands widely utilized in coordination chemistry. To further enrich this family and assess the potential impact of oxalyldihydrazide-derived Schiff bases in the realms of coordination che...

Salen ligands are a class of Schiff bases simply obtained through condensation of two molecules of a hydroxyl-substituted aryl aldehyde with an achiral or chiral diamine. The prototype salen, or N,N′-bis(salicylidene)ethylenediamine has a long...

The coordination chemistry of a hydrazinylpyrazine-derived Schiff base ligand (L1), formed in situ from salicylaldehyde and 2-hydrazinopyrazine, with Fe(III) salts has been systematically investigated under varied synthetic conditions. Six discrete F...

The design and synthesis of magnets with low dimensionality is currently an attractive research topic. The reaction of a Schiff base metal complex with simple molybdate has led to the formation of a new {Mn^III-Schiff-base}-decorated molybdate heterom...

2-(((2,7-Dihydroxynaphthalen-1-yl)methylene)amino)-3′,6′-bis(ethylamino)-2′,7′-dimethylspiro[isoindoline-1,9′-xanthen]-3-one was synthesized using Rhodamine 6G hydrazide (prepared using literature methods) and commercial...

A new flexible fluorescent compound L derived from 1,5-bis(2-aminophenoxy)-3-oxapentane (A) has been synthesized by classical Schiff-base reaction between (A) and 2,2´-bithiophene carbaldehyde (B). The same synthesis was reproduced by a green methodo...

The tetranuclear iron(III) compounds [Fe₄(μ₃-O)₂(μ-L^Z)₄] (1–3) were obtained by reaction of FeCl₃ with the shortened salen-type N₂O₂ tetradentate Schiff bases N,N’-bis(salicylidene)-o-Z-phenylmethanediamine H₂L^Z (Z = NO₂, Cl and OMe...

In the present work, a series of new 1-{5-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-1,3,4-oxadiazol-3-acetyl-2-aryl-2H/methyl derivatives were synthesized through a multistep reaction sequence. The compounds were synthesized by the condensation of vario...

Although spontaneous or complexation-induced reductions of Cu^II to Cu^I have occasionally been observed, controlling these processes remains a challenge. Herein, we report the synthesis of Cu^I complexes via the complexation-induced reduction of Cu^II c...

A new fluorescent di-imine compound containing two naphthalene groups has been synthesized by classical Schiff-base reaction between 2,2’-[1,3-phenylene­bis­(methyleneoxy)]dibenzaldehyde and 1-naphthylmethylamine. The new bischromophoric compound has...

The reduction of 4-nitrophenol to 4-aminophenol by sodium borohydride was used as a model to test the catalytic activity of copper(II) complexes containing N,O-chelating Schiff base ligands. In this study, a series of copper(II) complexes containing...

The thermal condensation of 3-(2-Furyl)acrolein with 2-Amino-6-ethoxybenzothiazole generated a new Schiff base, (1E,2E)-N-(6-ethoxybenzo[d]thiazol-2-yl)-3-(furan-2-yl)prop-2-en-1-imine (L), with general formula of C₁₆H₁₄N₂O₂S. Also, a series of lanth...

New Pd^II–Ln^III–Pd^II complexes of hexadentate N₂O₄ Schiff base ligand (H₄L: N,N′-bis(2,3-dihydroxybenzylidene)-1,3-diamino-2,2-dimethylpropane) with Eu (1), Tb (2), Er (3) and Yb (4) ([Pd₂Eu(H₂L)₂NO₃](NO₃)₂∙2H₂O∙2CH₃OH 1, [Pd₂Ln(H₂L)...

Iron(II)-Schiff base complexes are a well-studied class of spin-crossover (SCO) active species due to their ability to interconvert between a paramagnetic high spin-state (HS, S = 2, ⁵T₂) and a diamagnetic low spin-state (LS, S = 0, ¹A₁) by external...

A mixed-valent trinuclear complex with 1,3-bis(5-chlorosalicylideneamino)-2-propanol (H₃clsalpr) was synthesized, and the crystal structure was determined by the single-crystal X-ray diffraction method at 90 K. The molecule is a trinuclear Co^III-Co^II...

Tetranuclear Mn^II₂Mn^III₂ complexes with 1,3-bis(5-bromo-3-metoxysalicylidenaminomethyl)-2-propanol (H₃bmsap) and 1,3-bis(5-chloro-3-methoxysalicylidenaminomethyl)-2-propanol (H₃cmsap), [Mn₄(bmsap)₂(CH₃CO₂)₃(CH₃O)] (3) and [Mn₄(cmsap)₂(CH₃CO₂)₃(CH₃O)]...