Municipal and agricultural waste treatment is one of the key elements of reducing environmental impact with direct effects on the economy and society. Algal technology has been tested to enable effective recycling and valorisation of wastewater nutri...
Marine algae are emerging as important biological resources for the discovery and development of bioactive compounds with applications across food, pharmaceutical, cosmetic, agricultural, aquaculture, environmental, and biotechnological systems. This...
The emergence of the Coronavirus Disease 2019 (COVID-19) caused by the SARS-CoV-2 virus has led to an unprecedented pandemic, which demands urgent development of antiviral drugs and antibodies; as well as prophylactic approaches, namely vaccines. Alg...
Microalgae represent some of the most promising eukaryotic platforms in biotechnology due to their rapid growth, simple cultivation requirements, reliance on sunlight as a primary energy source, and ability to synthesize high-value bioactive compound...
Algae rarely occur as solitary phototrophs in nature or engineering; instead, they are embedded in complex bacterial consortia that control their physiology, productivity and ecological performance. The phycosphere, a microscale niche rich in algal e...
Chlamydomonas reinhardtii (C. reinhardtii) is a single-cell green alga that can be easily genetically manipulated. With its favorable characteristics of rapid growth, low cost, non-toxicity, and the ability for post-translational protein modification...
MYB transcription factors (TFs) represent a conserved family of DNA-binding regulators involved in diverse cellular and physiological processes. MYB TFs are well-characterized in terrestrial plants, but their evolutionary history and functional diver...
The anaerobic digestion, AD, process presents a solution for sustainable waste management, greenhouse gas mitigation and energy production for growing population needs and requirements. Adopting a biorefinery approach that utilises different feedstoc...
Chlamydomonas reinhardtii is a well-established model system for basic research questions ranging from photosynthesis and organelle biogenesis, to the biology of cilia and basal bodies, to channelrhodopsins and photoreceptors. More recently, Chlamydo...
Many dinoflagellates of the genus Alexandrium are well known for being responsible for harmful algal blooms (HABs), producing potent toxins that cause damages to other marine organisms, aquaculture, fishery, tourism, as well as induce human intoxicat...
The pennate diatom Phaeodactylum tricornutum is a model organism able to synthesize industrially-relevant molecules. Commercial-scale cultivation currently requires large monocultures, prone to bio-contamination. However, little is known about the id...
Astaxanthin from Haematococcus pluvialis is commercially produced in a two-stage process, involving green vegetative (macrozooid) and red aplanospore stages. This approach has been scaled up to an industrial process but constraints limit its commerci...
Management of nutrient inputs and usage of nuisance biomass as feedstock for bioenergy may be the solution of coastal lagoons eutrophication. We studied the species composition, photosynthetic pigments (Chl-a and Chl-c) and performance (OJIP-kinetics...
The protein and polyunsaturated fatty acid (PUFA) enrichment of microalgae can improve their nutritional value for larvae of various reared organisms. Protein enrichment can be achieved by increasing nitrogen concentration and selecting nitrogen sour...
The increasing cultivation of microalgae in photobioreactors warrants efficient and non-invasive methods to quantify biomass density in real time. Nephelometric turbidity assessment, a method that measures light scatter by particles in suspension, wa...
The need to reduce costs associated with the production of microalgae biomass has encouraged the coupling of process with wastewater treatment. Emerging pollutants in municipal, industrial, and agricultural wastewaters, ranging from pharmaceuticals t...
Uneaten feed and feces are major sources of waste in aquaculture systems, which lead to the eutrophication of water bodies. This study proposes a multidisciplinary approach to the valorization of two types of aquaculture waste. The first component of...
The social amoeba Dictyostelium discoideum is a versatile biological model widely used in drug discovery and studying cellular stress responses. However, its application for cytotoxicity evaluation of natural products, particularly algal-derived comp...
In the present study, the recovery of valuable molecules of proven anti-inflammatory and antimicrobial activity of the acidophilic microalga Coccomyxa onubensis (C. onubensis) were evaluated using green technologies based on ultrasound-assisted extra...
Algae represent one of the most metabolically diverse and ecologically significant groups of photosynthetic organisms, contributing fundamentally to global biogeochemical cycles while offering major potential for biotechnology applications such as bi...
With the increase in biotechnological, environmental, and nutraceutical importance of algae, about 100 whole genomic sequences of algae have been published, and this figure is expected to double in the coming years. The phenotypic and ecological dive...
Photosynthetic microbes are gaining increasing attention as heterologous hosts for the light-driven, low-cost production of high-value recombinant proteins. Recent advances in the manipulation of unicellular algal genomes offer the opportunity to est...
Microalgae have emerged as a promising platform for production of carbon- and energy- rich molecules, notably starch and oil. Establishing an economically viable algal biotechnology sector requires a holistic understanding of algal photosynthesis, ph...
Nanomaterials (NMs) are becoming more commonly used in microalgal biotechnology to empower the production of algal biomass and valuable metabolites, such as lipids, proteins, and exopolysaccharides. It provides an effective and promising supplement t...
Nowadays, there is an interest in biomedical and nanobiotechnological studies, such as studies on carotenoids as antioxidants and studies on molecular markers for cardiovascular, endocrine, and oncological diseases. Moreover, interest in industrial p...
Algae are becoming a strategic source of fuels, food, feedstocks, and biologically active compounds. This potential has stimulated the development of innovative analytical methods focused on these microorganisms. Algal lipids are among the most promi...
High salinity is a challenging environmental stress for organisms to overcome. Unicellular photosynthetic microalgae are especially vulnerable as they have to grapple not only with ionic imbalance and osmotic stress but also with the generated reacti...
Microalgal lipids are essential for biofuel and dietary supplement production. Lipid engineering for higher production has been studied for years. However, due to the complexity of lipid metabolism, single-gene engineering gradually encounters bottle...
Microalgae are the richest source of natural carotenoids, which are valuable pigments with a high share of benefits. Often, carotenoid-producing algae inhabit specific biotopes with unfavorable or even extremal conditions. Such biotopes, including al...
Methicillin-resistant Staphylococcus aureus (MRSA), a multidrug-resistant pathogen, poses a significant threat to global healthcare. This review evaluates the potential of marine algal metabolites as novel antibacterial agents against MRSA. We explor...
Worldwide, algal biofuel research and development efforts have focused on increasing the competitiveness of algal biofuels by increasing the energy and financial return on investments, reducing water intensity and resource requirements, and increasin...
Terpenoids are enormous and different types of naturally occurring metabolites playing an important role in industrial applications. Cost-effective and sustainable production of terpenoids at commercial scale is the big challenge because of its low a...
Microalgae have been considered as one of the most promising biomass feedstocks for various industrial applications such as biofuels, animal/aquaculture feeds, food supplements, nutraceuticals, and pharmaceuticals. Several biotechnological challenges...
Natural medicines refer to products derived from nature that exhibit pharmacological properties [...]
Marine macroalgae (seaweeds) are important primary global producers, with a wide distribution in oceans around the world from polar to tropical regions. Most of these species are exposed to variable environmental conditions, such as abiotic (e.g., li...
Taxadiene, a diterpene hydrocarbon, is the first committed intermediate in the biosynthesis of paclitaxel, a crucial anticancer drug. Its efficient production remains a key bottleneck for heterologous paclitaxel production. Although chloroplasts prov...
Although extensive research has been conducted on algal polysaccharides worldwide, Mediterranean species remain comparatively understudied, despite the region’s rich biodiversity and the presence of several endemic taxa with promising biotechno...
The review summarizes the available knowledge on toxins and their producers from rather disparate algal assemblages of aeroterrestrial, airborne and other versatile extreme environments (hot springs, deserts, ice, snow, caves, etc.) and on phycotoxin...
Marine macroalgae represent a versatile and sustainable platform within blue biotechnology, offering structurally diverse polysaccharides that are making significant contributions to next-generation therapeutical applications. Algae are rich sources...
Haematococcus lacustris is a natural source of a valuable ketocarotenoid astaxanthin. Under autotrophic growth conditions, it exists in the form of a community with bacteria. The close coexistence of these microorganisms raises two questions: how bro...
Alternative splicing (AS) is a regulatory mechanism of post-transcriptional regulation that plays an important role in plant response to abiotic stresses. However, corresponding research involving the mechanism of AS in the nitrogen starvation respon...
Microalgae are promising microorganisms used to produce value-added products or to develop sustainable approaches for environmental remediation. The ATP-binding cassette proteins (ABCs) of Chlamydomonas reinhardtii have been characterized as indispen...
Eukaryotic green microalgae show considerable promise for the sustainable light-driven biosynthesis of high-value fine chemicals, especially terpenoids because of their fast and inexpensive phototrophic growth. Here, the novel isopentenol utilization...
Porous substrate bioreactors (PSBRs) are a new technology to grow microalgae immobilized in a dense culture and solve some problems linked to suspended cultivation. During recent years, this technology has been used in laboratory and pilot setups in...
Microalgae-based biodiesel is increasingly recognized as an alternative to crop-based biodiesel. In this study, 10 local strains of dinoflagellates collected from Hong Kong waters, including a monoculture and field sample of Scrippsiella sp. isolated...
Incorporating microalgae into integrated biotechnologies facilitates rational resource management. Cultivation of microalgae in various types of wastewater offers a number of advantages: safe disposal of liquid waste, restoration of water resources,...
Chlorella vulgaris is of great importance in numerous exploratory or industrial applications (e.g., medicals, food, and feed additives). Rapid quantification of algal biomass is crucial in photobioreactors for the optimization of nutrient management...
Municipal wastewater represents an underutilized secondary biomass resource rich in organic carbon and nutrients that can be valorized through biotechnological conversion. In this study, we developed an integrated multi-microbial biorefinery platform...
The regulatory role of some reactive oxygen species (ROS) and reactive nitrogen species (RNS), such as hydrogen peroxide or nitric oxide, has been demonstrated in some higher plants and algae. Their involvement in regulation of the organism, tissue a...
Algal lipidomics is a new field of research that is gaining increasing popularity. The use of high-performance liquid chromatography–mass spectrometry (HPLC-MS) has made it possible to accurately determine the structure of each lipid molecule i...
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