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Biosynthesis of Marine Bioactive Metabolites and Biomedical Applications

A Special Issue of Marine Drugs (ISSN 1660-3397) belonging to the section "Synthesis and Medicinal Chemistry of Marine Natural Products".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 53

Editor


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Guest Editor
College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China
Interests: microbial degradation of pollutants; resource utilization of marine microalgae and microorganisms, including the research and application of biologically active substances (DHA, astaxanthin); bioenergy (bioethanol, biodiesel, biogas fuel, biomicro fuel cells)
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Special Issue Information

Dear Colleagues,

Marine ecosystems harbor abundant and unique biological resources, which produce a large number of structurally diverse and biologically active secondary metabolites. These marine bioactive substances have outstanding advantages such as novel chemical structures, unique pharmacological activities and low toxic side effects, and have become crucial treasure resources for the development of new biomedical drugs, functional health products and clinical auxiliary therapies. In recent years, with the rapid development of synthetic biology, microbial engineering and marine biotechnology, in-depth exploration of the biosynthesis mechanism of marine bioactive substances, optimization of synthesis pathways, and efficient acquisition of high-value active metabolites have become hot research directions in marine biology and translational medicine.

This Special Issue focuses on the latest research progress in the biosynthesis of marine bioactive substances and their innovative medical applications. We warmly welcome both high-quality original research papers and comprehensive review articles. Original research submissions are encouraged to report novel findings regarding synthetic regulatory mechanisms, efficient biosynthesis strategies, heterologous expression systems, pharmacological functions, and preclinical therapeutic potential of marine bioactive compounds. Review papers are highly appreciated to provide systematic summaries, in-depth discussions, current challenges, and future prospects of this rapidly developing field, covering anti-tumor, anti-inflammatory, antioxidant, immunomodulatory, and antimicrobial applications. We also welcome studies on the optimization of biosynthetic processes, yield improvement strategies, and biomanufacturing technologies of marine active metabolites, so as to promote the basic research transformation and industrial application of marine biomedical resources.

The topics of interest include, but are not limited to, the following: biosynthesis and metabolic regulation of marine bioactive metabolites; synthetic biology modification and efficient synthesis of marine active substances; isolation, identification and functional verification of novel marine bioactive compounds; pharmacological mechanism research on marine active substances; preclinical research and translational medical application of marine bioactive substances; and biomanufacturing and process optimization of marine biomedical active products.

Dr. Xuewei Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine bioactive metabolites
  • microalgal bioactive compounds
  • biosynthesis
  • synthetic biology
  • biomedical application
  • pharmacological activity
  • metabolic regulation
  • anti-inflammatory activity
  • antitumor activity
  • marine drug discovery

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Published Papers

This special issue is now open for submission.
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